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1. 发明申请

US20220229138A1 PROCESS OF ENHANCING NITROGEN VACANCY (NV) CENTER SPIN EXCITATION IN HYPERPOLARIZATION APPLICATION 有权
公开(公告)号：US20220229138A1
公开(公告)日：2022-07-21
申请号：US17609355
申请日：2019-10-10
申请人： MASTER DYNAMIC LIMITED , GOLDWAY TECHNOLOGY LIMITIED
发明人： Ka Wing CHENG , Kong CHAN , Chun Hong SHAM , Juan CHENG , Koon Chung HUI
IPC分类号： G01R33/56 , G01R33/28
摘要： A process for enhancing polarization of 13C for subsequence MRI imaging, the process comprising providing a suspension consisting of a first plurality of particulates having NV centers and a second plurality of particulates for providing internal reflection of light with wavelength for the excitement of NV centers and 13C; and applying light, magnetic field and microwave to said suspension, such that the NV centers are polarized and such that the electron spins of the VN centres are transferred to 13C atoms upon the Rabi frequency of the NV centres matching the Larmor frequency of 13C; wherein the particulates of the second plurality reflect and transmit the light through the suspension such that said light is distributed through said suspension.

2. 发明申请

US20220355416A1 METHOD OF MARKING A SOLID-STATE MATERIAL, MARKINGS FORMED FROM SUCH METHODS AND SOLID-STATE MATERIALS MARKED ACCORDING TO SUCH A METHOD 有权
公开(公告)号：US20220355416A1
公开(公告)日：2022-11-10
申请号：US17624325
申请日：2020-07-24
申请人： MASTER DYNAMIC LIMITED
发明人： Yau Chuen YIU , Ka Wing CHENG , Koon Chung HUI
IPC分类号： B23K26/359 , G06V20/80 , B23K26/0622 , B23K26/06 , B23K26/082 , B23K26/08
摘要： A process of forming a non-optically detectable authentication marking (210,320, 410,535) in a diamond (200,300). Authentication marking (210,320,410,535) is formed adjacent the outer surface of an article formed from a diamond material having intrinsic optical centers. Method includes the step of applying an image of predesigned authentication marking(210,320,410,535) to a region (201,310,530) of a diamond (200,300) at or adjacent the surface of the diamond (200,300) by way of a direct laser writing; wherein the fluorescence background of the diamond material from intrinsic optical center is suppressed by authentication marking(210,320, 410, 535) under fluorescent imaging, such that the non-optically detectable identifiable authentication marking (210,320,410,535) is viewable against the fluorescence background at the region (201,310,530) of the diamond (200,300) where the authentication marking (210,320,410,535) is applied.

3. 发明申请

US20220274291A1 METHOD OF MARKING A DIAMOND, MARKINGS FORMED FROM SUCH METHODS AND DIAMONDS MARKED ACCORDING TO SUCH METHOD 有权
公开(公告)号：US20220274291A1
公开(公告)日：2022-09-01
申请号：US17624332
申请日：2020-07-24
申请人： MASTER DYNAMIC LIMITED
发明人： Yau Chuen YIU , Ka Wing CHENG , Koon Chung HUI
IPC分类号： B28D5/04 , B42D25/435 , B42D25/324
摘要： A process of forming a non-optically detectable authentication marking (110), includes the step of: applying a marking at a surface of a diamond (200) using a focused ion beam (FIB) writing process so as to provide a non-optically detectable authentication marking (110) which is formed by alteration in the optical characteristics of a portion of the diamond material at the outer surface of the diamond to form a marked portion; wherein the marking is optically invisible, and wherein the marking is viewable by an imaging method which provides an observable contrast between the portion of the diamond having altered optical characteristics and the non-marked portion of the diamond. The marking process can assist in the prevention of the counterfeiting of precious articles, and be of assistance in the incident of theft. A marking, a diamond, a process of viewing a marking on a diamond are further disclosed.

4. 发明申请

US20150101365A1 METHOD OF PROVIDING MARKINGS TO PRECIOUS STONES INCLUDING GEMSTONES AND DIAMONDS, AND MARKINGS AND MARKED PRECIOUS STONES MARKED ACCORDING TO SUCH A METHOD 审中-公开
标题翻译：向包括钻石和钻石在内的重要石碑提供标记的方法，以及根据这种方法标记的标记和标记的重要石碑
公开(公告)号：US20150101365A1
公开(公告)日：2015-04-16
申请号：US14286306
申请日：2014-05-23
申请人： Master Dynamic Limited
发明人： Koon Chung HUI , Wing Chi TANG , Ho CHING
IPC分类号： G09F3/00 , G01J1/08 , G02B5/18 , G09F23/00 , A44C17/00
CPC分类号： G09F3/00 , A44C17/00 , B23K26/0006 , B23K26/355 , B23K2103/50 , B41M5/24 , G01J1/08 , G01N21/87 , G02B5/1842 , G02B5/1857 , G02B5/1861 , G09F23/00
摘要： An identifiable mark on a portion of a polished facet of a surface of an article and being identifiable by an optical magnifying viewing device, said identifiable mark comprising a nano-structure formed by a two-dimensional or a three-dimensional lattice of a plurality of discrete nanometer sized recessed or protruded entities, wherein said entities are arranged within a predefined region of said polished facet in a predetermined arrangement in relation to each other and such that an outer interface surface between the facet of the article and air is formed and an inner interface surface between the facet of the article and air is formed. Said predetermined arrangement of said entities is non-uniform and non-periodic arrangement, and wherein said entities are sized and shaped so as to cause optical scattering upon reflection of incident light and the distance from the inner interface surface to the outer interface surface is greater than the amplitude of the non-marked portion of said polished face. Upon reflection of incident light having one or more predetermined wavelengths by said lattice at a predetermined angle of incidence to said lattice, interference due to scattering of light from said lattice is induced such that said reflected light has a variation in intensity providing one or more local maxima of one or more wavelengths. Said mark is identifiable by way of an optical magnifying viewing device inclined at a requisite viewing angle such that a local maxima is detected.
摘要翻译：在物品表面的抛光小面的一部分上的可识别的标记并且可由光学放大观察装置识别，所述可识别标记包括由多个或多个的二维或三维网格形成的纳米结构离散的纳米尺寸的凹入或突出的实体，其中所述实体以相对于彼此的预定布置布置在所述抛光小面的预定区域内，并且使得形成制品的小面与空气之间的外部界面表面，形成制品的小面与空气之间的界面。所述实体的所述预定布置是不均匀和非周期性布置，并且其中所述实体的尺寸和形状被设计成在入射光反射时引起光学散射，并且从内部界面表面到外部界面表面的距离更大比所述抛光面的未标记部分的幅度大。通过所述格子以预定的入射角对所述格子反射具有一个或多个预定波长的入射光，由于来自所述晶格的光的散射引起的干涉被引起，使得所述反射光具有提供一个或多个局部一个或多个波长的最大值。所述标记可通过以必要的视角倾斜的光学放大观察装置来识别，从而检测到局部最大值。

5. 发明申请

US20220031863A1 NANOPARTICLE DELIVERY SYSTEM 有权
公开(公告)号：US20220031863A1
公开(公告)日：2022-02-03
申请号：US17299568
申请日：2019-12-03
申请人： MASTER DYNAMIC LIMITED
发明人： Ka Wing CHENG , Koon Chung HUI , Ching Tom KONG
IPC分类号： A61K47/69 , A61K47/64
摘要： A conjugate (110) comprising a nanoparticle (210) for delivery of a drug to a treatment site in the body of a subject; a drug molecule (220) releasably linked to said nanoparticle (210), wherein said drug molecule (220) has a therapeutic effect at the treatment site in the body of the subject; and a disease targeting molecule (230) releasably linked to said nanoparticle (210); wherein upon said conjugate (110) being adjacent diseased tissue (240) of a subject, said disease targeting molecule (230) retains the conjugate (110) adjacent said diseased tissue (240); said drug molecule (220) is released from said nanoparticle (110) so as to provide a therapeutic effect to said diseased tissue (240); and said disease targeting molecule (230) is subsequently released from said nanoparticle (210) such that retention of the nanoparticle (210) is released, and such that the nanoparticle (210) is dispersible from said diseased tissue (240).

6. 发明申请

US20210268123A1 DRUG FORMULATION FOR DERMAL DISEASES 有权
公开(公告)号：US20210268123A1
公开(公告)日：2021-09-02
申请号：US17254685
申请日：2019-06-21
申请人： MASTER DYNAMIC LIMITED
发明人： Ka Wing CHENG , Wing Chi TANG , Koon Chung HUI
IPC分类号： A61K47/69 , A61K31/436 , A61K9/00 , A61K41/00
摘要： A conjugate comprising at least one calcineurin phosphatase inhibitor and a nanodiamond.

7. 发明申请

US20230137188A1 HYPERPOLARISATION DEVICE, SYSTEM AND PROCESS 有权
公开(公告)号：US20230137188A1
公开(公告)日：2023-05-04
申请号：US17802470
申请日：2021-02-26
申请人： MASTER DYNAMIC LIMITED
发明人： Yau Chuen YIU , Juan CHENG , Koon Chung HUI
IPC分类号： G01R33/56 , G01R33/28
摘要： A device(100a(i), 100a(ii), 100a(iii), 100a(iv), 200 for cis-tracing polarization of 12C isotope-based magnetic resource imaging contrast agents, comprising one or more diamond material structures(120(i), 120(ii), 120(iii), 120(iv), 210, 220) and one or more channels(105a(i), 105a (ii), 105a (iii), 105a (iv), 205) provided adjacent to the diamond material structures 120(i), 120(ii), 120(iii), 120(iv), 210, 220); the diamond material structures 120(i), 120(ii), 120(iii), 120(iv), 210, 220) provide a source of negatively charged nitrogen vacancy celles for polarization of a 13C iso-type-based magnetic measure imaging contrast agesi disguised in one or more channels(105a (i), 105a (ii), 105a (iii), 105a (iv), 205) and cis diamond material structure(120(i), 120(ii), 120(iii), 120(iv), 210, 220) provides a light guide for light for excitation of nitrogen vacancy celles for polarization of 13C isotope-based magnetic resource imaging contrast agent.

8. 发明申请

US20210267854A1 SKIN HYDRATION COMPOSITION 有权
公开(公告)号：US20210267854A1
公开(公告)日：2021-09-02
申请号：US17253339
申请日：2019-06-21
申请人： MASTER DYNAMIC LIMITED
发明人： Ka Wing CHENG , Wng Chi TANG , Koon Chung HUI
IPC分类号： A61K8/02 , A61K8/19 , A61Q19/00 , A61K8/86 , A61K45/06
摘要： A topically administrable moisturising composition for moisturising the skin of a subject, said moisturising composition comprising (i) a plurality of conjugates wherein each conjugate is comprised of a nanodiamond and a plurality of water molecules, and (ii) a carrier media for topical administration.

9. 发明申请

US20210172953A1 CANCER CELL DETECTION AND IMAGING SYSTEM, PROCESS AND PRODUCT 有权
公开(公告)号：US20210172953A1
公开(公告)日：2021-06-10
申请号：US17254736
申请日：2019-06-21
申请人： MASTER DYNAMIC LIMITED
发明人： Ka Wing CHENG , Koon Chung HUI , Ching Tom KONG
IPC分类号： G01N33/574 , G01N21/64 , G01N33/58
摘要： A method of distinguishing cancerous cells and healthy cells of a subject from each other comprises the steps: (i) contacting a region of tissue of a subject suspected of including at least some cancer cells with a plurality of nanodiamonds, wherein the plurality of nanodiamonds comprise a first plurality of conjugates, wherein the conjugates of the first plurality of conjugates consist of first nanodiamonds and one or more cancer cell targeting agents, wherein the first nanodiamonds have a first type of colour center, and a second plurality of conjugates, wherein the conjugates of the second plurality of conjugates consist of second nanodiamonds and one or more healthy cell targeting agents, wherein the second nanodiamonds have a second type of colour center; and (ii) applying light of a first wavelength so as to excite the first type of colour center and applying light of a second wavelength so as to excite the second type of colour center, wherein upon contacting the region of tissue with the plurality of nanodiamonds, cancer cells are adhered to the first plurality of conjugates, and healthy cells are adhered to the second plurality of conjugates; wherein upon applying light to the region of tissue, the colour centers of the nanodiamonds of the first plurality of conjugates adhered to cancer cells emit fluorescence at a first wavelength, and the colour centers of the nanodiamonds of the second plurality of conjugates adhered to healthy cells emit fluorescence at a second wavelength; and wherein the colour contrast between the two wavelengths and the positions of respective conjugates delineate the area of cancer cells and the area of healthy cells from each other.

10. 发明申请

US20140356577A1 METHOD OF MARKING MATERIAL AND SYSTEM THEREFORE, AND MATERIAL MARKED ACCORDING TO SAME METHOD 有权
标题翻译：标记材料及其系统的方法，以及根据相同方法标记的材料
公开(公告)号：US20140356577A1
公开(公告)日：2014-12-04
申请号：US14290369
申请日：2014-05-29
申请人： Master Dynamic Limited
发明人： Koon Chung HUI , Ho CHING , Ching Tom KONG
IPC分类号： B01J19/08
CPC分类号： B01J19/081 , B41M3/14 , C30B29/04 , C30B29/16 , C30B29/20 , C30B29/34 , C30B33/04 , H01J37/00 , H01J37/3178 , Y10T428/24355
摘要： A method of forming one or more protrusions on an outer surface of a polished face of a solid state material, said method including the step of applying focused inert gas ion beam local irradiation towards an outer surface of a polished facet of a solid state material in a way of protruding top surface material; wherein irradiated focused inert gas ions from said focused inert gas ion bean penetrate the outer surface of said polished facet of said solid state material; and wherein irradiated focused inert gas ions cause expansive strain within the solid state crystal lattice of the solid state material below said outer surface at a pressure so as to induce expansion of solid state crystal lattice, and form a protrusion on the outer surface of the polished face of said solid state material.
摘要翻译：一种在固体材料的抛光面的外表面上形成一个或多个突起的方法，所述方法包括以下步骤：将聚焦的惰性气体离子束局部照射施加到固态材料的抛光小面的外表面上突出表面材料的方式; 其中来自所述聚焦的惰性气体离子束的照射聚焦的惰性气体离子穿透所述固态材料的所述抛光面的外表面; 并且其中照射聚焦的惰性气体离子在压力下在所述外表面下方的固态材料的固态晶格内引起膨胀应变，以引起固态晶格的膨胀，并在抛光的外表面上形成突起所述固态材料的表面。

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