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1. 发明授权

US09256951B2 System for rapid and accurate quantitative assessment of traumatic brain injury 有权
标题翻译：快速准确地定量评估创伤性脑损伤的系统
公开(公告)号：US09256951B2
公开(公告)日：2016-02-09
申请号：US13514713
申请日：2010-11-17
申请人： Lyubomir Georgiev Zagorchev , Elizabeth Anne Morre , Matthew A. Garlinghouse , Robert M. Roth , Thomas W. McAllister , Dieter Geller , Jochen Peters , Juergen Weese , Yuechen Qian
发明人： Lyubomir Georgiev Zagorchev , Elizabeth Anne Morre , Matthew A. Garlinghouse , Robert M. Roth , Thomas W. McAllister , Reinhard Kneser , Dieter Geller , Jochen Peters , Juergen Weese , Yuechen Qian
IPC分类号： G06T7/00 , G06T17/30 , G06T19/20
CPC分类号： G06T7/0089 , G06T7/0012 , G06T7/149 , G06T2200/24 , G06T2207/10081 , G06T2207/30016
摘要： A system and method for automatic segmentation, performed by selecting a deformable model of an anatomical structure of interest imaged in a volumetric image, the deformable model formed of a plurality of polygons including vertices and edges, displaying the deformable model on a display, detecting a feature point of the anatomical structure of interest corresponding to each of the plurality of polygons and adapting the deformable model by moving each of the vertices toward the corresponding feature points until the deformable model morphs to a boundary of the anatomical structure of interest, forming a segmentation of the anatomical structure of interest.
摘要翻译：一种用于自动分割的系统和方法，通过选择在体积图像中成像的感兴趣的解剖结构的可变形模型来执行，所述可变形模型由包括顶点和边缘的多个多边形形成，在显示器上显示可变形模型，感兴趣的解剖结构的特征点对应于多个多边形中的每一个，并且通过将每个顶点朝向对应的特征点移动来适配可变形模型，直到可变形模型变形为感兴趣的解剖结构的边界，形成分割的感兴趣的解剖结构。

2. 发明申请

US20120327075A1 SYSTEM FOR RAPID AND ACCURATE QUANTITATIVE ASSESSMENT OF TRAUMATIC BRAIN INJURY 有权
标题翻译：快速和精确定量评估TRAUMATIC脑损伤系统
公开(公告)号：US20120327075A1
公开(公告)日：2012-12-27
申请号：US13514713
申请日：2010-11-17
申请人： Lyubomir Georgiev Zagorchev , Elizabeth Anne Morre , Matthew A. Garlinghouse , Robert M. Roth , Thomas W. McAllister , Reinhard Kneser , Dieter Geller , Jochen Peters , Juergen Weese , Yuechen Qian
发明人： Lyubomir Georgiev Zagorchev , Elizabeth Anne Morre , Matthew A. Garlinghouse , Robert M. Roth , Thomas W. McAllister , Reinhard Kneser , Dieter Geller , Jochen Peters , Juergen Weese , Yuechen Qian
IPC分类号： G06T7/00
CPC分类号： G06T7/0089 , G06T7/0012 , G06T7/149 , G06T2200/24 , G06T2207/10081 , G06T2207/30016
摘要： A system and method for automatic segmentation, performed by selecting a deformable model of an anatomical structure of interest imaged in a volumetric image, the deformable model formed of a plurality of polygons including vertices and edges, displaying the deformable model on a display, detecting a feature point of the anatomical structure of interest corresponding to each of the plurality of polygons and adapting the deformable model by moving each of the vertices toward the corresponding feature points until the deformable model morphs to a boundary of the anatomical structure of interest, forming a segmentation of the anatomical structure of interest.
摘要翻译：一种用于自动分割的系统和方法，通过选择在体积图像中成像的感兴趣的解剖结构的可变形模型来执行，所述可变形模型由包括顶点和边缘的多个多边形形成，在显示器上显示可变形模型，感兴趣的解剖结构的特征点对应于多个多边形中的每一个，并且通过将每个顶点朝向对应的特征点移动来适配可变形模型，直到可变形模型变形为感兴趣的解剖结构的边界，形成分割的感兴趣的解剖结构。

3. 发明申请

US20100293505A1 ANATOMY-RELATED IMAGE-CONTEXT-DEPENDENT APPLICATIONS FOR EFFICIENT DIAGNOSIS 审中-公开
标题翻译：与解剖学相关的图像依赖性应用程序进行有效的诊断
公开(公告)号：US20100293505A1
公开(公告)日：2010-11-18
申请号：US12376999
申请日：2007-08-07
申请人： Gundolf Kiefer , Helko Lehmann , Dieter Geller , Hauke Schramm , Jochen Peters , Olivier Ecabert , Juergen Weese
发明人： Gundolf Kiefer , Helko Lehmann , Dieter Geller , Hauke Schramm , Jochen Peters , Olivier Ecabert , Juergen Weese
IPC分类号： G06F3/048
CPC分类号： G16H40/63
摘要： The invention relates to a system (100) for obtaining information relating to segmented volumetric medical image data, the system comprising: a display unit (110) for displaying a view of the segmented volumetric medical image data on a display; an indication unit (115) for indicating a location on the displayed view; a trigger unit (120) for triggering an event; an identification unit (125) for identifying a segmented anatomical structure comprised in the segmented volumetric medical image data based on the indicated location on the displayed view in response to the triggered event; and an execution unit (130) for executing an action associated with the identified segmented anatomical structure, thereby obtaining information relating to the segmented volumetric medical image data. The action executed by the execution unit (130) may be displaying a name of the segmented anatomical structure, a short description of the segmented anatomical structure, or a hint on a potential malformation or malfunction of the segmented anatomical structure. Thus, the system (100) allows obtaining valuable information relating to the volumetric medical image data viewed by a physician on the display, thereby assisting the physician in medical diagnosing.
摘要翻译：本发明涉及一种用于获取与分段体积医学图像数据相关的信息的系统（100），该系统包括：显示单元（110），用于在显示器上显示分割的体积医学图像数据的视图; 指示单元（115），用于指示所显示的视图上的位置; 触发单元（120），用于触发事件; 识别单元（125），用于响应于触发的事件，基于所显示的视图上的指示位置来识别包含在所述分段体积医学图像数据中的分段解剖结构; 以及执行单元（130），用于执行与所识别的分段解剖结构相关联的动作，从而获得与分割的体积医学图像数据相关的信息。由执行单元（130）执行的动作可以显示分割的解剖结构的名称，分割的解剖结构的简短描述，或对分割的解剖结构的潜在畸形或故障的提示。因此，系统（100）允许获得与医生在显示器上观看的体积医学图像数据相关的有价值的信息，从而辅助医师进行医学诊断。

4. 发明申请

US20120082354A1 ESTABLISHING A CONTOUR OF A STRUCTURE BASED ON IMAGE INFORMATION 审中-公开
标题翻译：建立基于图像信息的结构轮廓
公开(公告)号：US20120082354A1
公开(公告)日：2012-04-05
申请号：US13377401
申请日：2010-06-18
申请人： Jochen Peters , Olivier Ecabert , Carsten Meyer , Reinhard Kneser , Juergen Weese
发明人： Jochen Peters , Olivier Ecabert , Carsten Meyer , Reinhard Kneser , Juergen Weese
IPC分类号： G06K9/48 , G06K9/00
CPC分类号： G06T7/149 , G06T7/0012 , G06T7/12 , G06T7/60 , G06T7/97 , G06T2207/10072 , G06T2207/20116 , G06T2207/30004
摘要： A system for establishing a contour of a structure is disclosed. An initialization subsystem (1) is used for initializing an adaptive mesh representing an approximate contour of the structure, the structure being represented at least partly by a first image, and the structure being represented at least partly by a second image. A deforming subsystem (2) is used for deforming the adaptive mesh, based on feature information of the first image and feature information of the second image. The deforming subsystem comprises a force-establishing subsystem (3) for establishing a force acting on at least part of the adaptive mesh, in dependence on the feature information of the first image and the feature information of the second image. A transform-establishing subsystem (4) is used for establishing a coordinate transform reflecting a registration mismatch between the first image, the second image, and the adaptive mesh.
摘要翻译：公开了一种用于建立结构轮廓的系统。初始化子系统（1）用于初始化表示结构的近似轮廓的自适应网格，该结构至少部分地由第一图像表示，并且该结构至少部分地由第二图像表示。变形子系统（2）用于基于第一图像的特征信息和第二图像的特征信息来变形自适应网格。变形子系统包括根据第一图像的特征信息和第二图像的特征信息来建立作用在自适应网格的至少一部分上的力的力建立子系统（3）。变换建立子系统（4）用于建立反映第一图像，第二图像和自适应网格之间的配准失配的坐标变换。

5. 发明申请

US20080304744A1 Method for Facilitating Post-Processing of Images Using Deformable Meshes 有权
标题翻译：使用可变形网格促进图像后处理的方法
公开(公告)号：US20080304744A1
公开(公告)日：2008-12-11
申请号：US12097855
申请日：2006-12-14
申请人： Jochen Peters , Olivier Ecabert , Juergen Weese , Christian Lorenz , Jens Von Berg
发明人： Jochen Peters , Olivier Ecabert , Juergen Weese , Christian Lorenz , Jens Von Berg
IPC分类号： G06T5/00
CPC分类号： G06T9/001 , G06T7/12 , G06T7/149 , G06T2207/10081 , G06T2207/20081 , G06T2207/30101
摘要： Method and system for facilitating post-processing of images using deformable meshes in which a deformable mesh model of an object such as an organ is extended by attaching information thereon in order to simplify and/or facilitate a desired post-processing task so that the post-processing task effected when the mesh is applied to the same object in an additional image can expeditiously use this information. The information may be attached to the mesh after its creation, for example, upon segmentation of the same object in some training image. The post-processing task can therefore be performed automatically without user interaction upon segmentation of the object in the additional image. Information is encoded on the mesh by enumerating a list of triangles or vertices of the mesh which have to be considered in the subsequent, post-processing task and by optionally providing additional parameters defining the precise post-processing algorithm(s) to be used.
摘要翻译：使用可变形网格促进图像后处理的方法和系统，其中通过在其上附加信息来扩展诸如器官的对象的可变形网格模型，以简化和/或促进期望的后处理任务，使得该帖子当将网格应用于附加图像中的同一对象时，处理任务即可快速使用此信息。信息可以在其创建之后附加到网格上，例如，在一些训练图像中对相同对象进行分割时。因此，在附加图像中的对象的分割之后，可以自动执行后处理任务，而无需用户交互。通过枚举在后续的后处理任务中必须考虑的网格的三角形或顶点列表以及可选地提供定义要使用的精确后处理算法的附加参数，将信息编码在网格上。

6. 发明授权

US08260586B2 Method of and a system for adapting a geometric model using multiple partial transformations 有权
标题翻译：使用多个部分变换来适应几何模型的方法和系统
公开(公告)号：US08260586B2
公开(公告)日：2012-09-04
申请号：US12067841
申请日：2006-09-20
申请人： Olivier Ecabert , Jochen Peters , Juergen Weese
发明人： Olivier Ecabert , Jochen Peters , Juergen Weese
IPC分类号： G06F7/60 , G06F17/10
CPC分类号： G06T7/149 , G06T7/12 , G06T2207/10072 , G06T2207/30048
摘要： The invention relates to a method (100) of adapting a geometric model to an image data comprising determining a first partial transformation for mapping a first part of the geometric model into the image data and a second partial transformation for mapping a second part of the geometric model into the image data. By determining the first partial transformation of the first part of the geometric model and the second partial transformation of the second part of the geometric model, the geometric model can assume more shapes and therefore can be more accurately adapted to an object comprised in the image data.
摘要翻译：本发明涉及一种将几何模型适应于图像数据的方法（100），包括确定用于将几何模型的第一部分映射到图像数据中的第一部分变换，以及用于映射几何的第二部分的第二部分变换模型进入图像数据。通过确定几何模型的第一部分的第一部分变换和几何模型的第二部分的第二部分变换，几何模型可以呈现更多的形状，因此可以更准确地适应包含在图像数据中的对象。

7. 发明申请

US20100135543A1 MEDICAL IMAGE VIEWING PROTOCOLS 有权
标题翻译：医学图像查看协议
公开(公告)号：US20100135543A1
公开(公告)日：2010-06-03
申请号：US11815452
申请日：2006-02-07
申请人： Juergen Weese , Eric Thelen , Gundolf Kiefer , Helko Lehmann , Ali Majidi , Jochen Peters
发明人： Juergen Weese , Eric Thelen , Gundolf Kiefer , Helko Lehmann , Ali Majidi , Jochen Peters
IPC分类号： G06K9/62
CPC分类号： G06T11/001
摘要： A method, computer program and device for creating a viewing protocol for medical images is described. At least a first site of interest is identified in a medical imaging data set captured from the patient. Patient record data or computer assisted detection information can be used to identify the site of interest, which may be a potential lesion. A viewing protocol for displaying medical images to a user is planned. The viewing protocol includes a viewing path along which an image of the site of interest will be displayed. The viewing protocol also includes a trigger associated with the site of interest. When the trigger event is encountered the dynamic mode of image display is reconfigured to dynamically highlight the site of interest. The viewing protocol can then be used to control the display of images so as to provide, for example, a virtual endoscope.
摘要翻译：描述了一种用于创建用于医学图像的观看协议的方法，计算机程序和设备。在从患者获取的医学成像数据集中识别至少第一感兴趣的位置。患者记录数据或计算机辅助检测信息可用于识别感兴趣的位点，这可能是潜在的病变。计划用于向用户显示医学图像的观看协议。观看协议包括观看路径，通过该观看路径将显示感兴趣的场所的图像。查看协议还包括与感兴趣的站点相关联的触发器。当遇到触发事件时，重新配置图像显示的动态模式以动态突出显示感兴趣的站点。然后可以使用观看协议来控制图像的显示，以便提供例如虚拟内窥镜。

8. 发明申请

US20090115796A1 PRIORI INFORMATION ENCODING FOR MANUAL ADAPTATION OF GEOMETRIC MODELS 审中-公开
标题翻译：用于手写适应几何模型的优先信息
公开(公告)号：US20090115796A1
公开(公告)日：2009-05-07
申请号：US12067840
申请日：2006-09-20
申请人： Juergen Weese , Olivier Ecabert , Jochen Peters
发明人： Juergen Weese , Olivier Ecabert , Jochen Peters
IPC分类号： G09G5/00
CPC分类号： G06T19/20 , G06T7/12 , G06T7/149 , G06T2207/10072 , G06T2207/20092 , G06T2207/30004 , G06T2219/2021
摘要： The invention relates to the adaptation method (200) of adapting a geometric model to an image data comprising a region selection step (230) for selecting a region of the geometric model and a manual adaptation step (235) for manually adapting the geometric model to the image data using a set of characteristics of the region comprised in the geometric model. Using a region-specific characteristic from the set of characteristics of the selected region, such as a region-specific parameter determining the deformation range, for manually adapting the geometric model to the image data, requires relatively fewer user interactions.
摘要翻译：本发明涉及将几何模型适应于包括用于选择几何模型的区域的区域选择步骤（230）的图形数据的适配方法（200）和用于手动调整几何模型的手动适应步骤（235）该图像数据使用包含在几何模型中的区域的一组特征。使用来自所选区域的特征的区域特定特征，例如用于手动将几何模型适配到图像数据的诸如确定变形范围的区域特定参数需要相对较少的用户交互。

9. 发明申请

US20090037154A1 Method Of And A System For Adapting A Geometric Model Using Multiple Partial Transformations 有权
标题翻译：用于使用多个部分变换来适应几何模型的系统的方法和系统
公开(公告)号：US20090037154A1
公开(公告)日：2009-02-05
申请号：US12067841
申请日：2006-09-20
申请人： Olivier Ecabert , Jochen Peters , Juergen Weese
发明人： Olivier Ecabert , Jochen Peters , Juergen Weese
IPC分类号： G06F17/10
CPC分类号： G06T7/149 , G06T7/12 , G06T2207/10072 , G06T2207/30048
摘要： The invention relates to a method (100) of adapting a geometric model to an image data comprising determining a first partial transformation for mapping a first part of the geometric model into the image data and a second partial transformation for mapping a second part of the geometric model into the image data. By determining the first partial transformation of the first part of the geometric model and the second partial transformation of the second part of the geometric model, the geometric model can assume more shapes and therefore can be more accurately adapted to an object comprised in the image data.
摘要翻译：本发明涉及一种将几何模型适应于图像数据的方法（100），包括确定用于将几何模型的第一部分映射到图像数据中的第一部分变换，以及用于映射几何的第二部分的第二部分变换模型进入图像数据。通过确定几何模型的第一部分的第一部分变换和几何模型的第二部分的第二部分变换，几何模型可以呈现更多的形状，因此可以更准确地适应包含在图像数据中的对象。

10. 发明授权

US08995777B2 Image registration apparatus 有权
标题翻译：图像配准装置
公开(公告)号：US08995777B2
公开(公告)日：2015-03-31
申请号：US13990530
申请日：2011-11-24
申请人： Jochen Peters , Juergen Weese , Helko Lehmann
发明人： Jochen Peters , Juergen Weese , Helko Lehmann
IPC分类号： G06K9/62 , G06T7/00
CPC分类号： G06T7/0046 , G06T7/344 , G06T7/75 , G06T2207/10072 , G06T2207/20016 , G06T2207/30048
摘要： The invention relates to an image registration apparatus for registering a first image and a second image with respect to each other. A model, which has a fixed topology, is adapted to the first image for generating a first adapted model and to the second image for generating a second adapted model, and corresponding image elements (40, 48, 49; 50, 58, 9) are determined in the first image and in the second image based on spatial positions of first image elements in the first image with respect to the first adapted model and spatial positions of second image elements in the second image with respect to the second adapted model. Since the model has a fixed topology, corresponding image elements can relatively reliably be found based on the adapted models, even if the first and second images show objects having complex properties like a heart, thereby improving the registration quality.
摘要翻译：本发明涉及一种用于相对于彼此登记第一图像和第二图像的图像配准装置。具有固定拓扑的模型适于产生第一适应模型的第一图像和用于产生第二适应模型的第二图像，以及对应的图像元素（40,48,49; 50,58,9）基于第一图像中的第一图像元素相对于第一适应模型的空间位置和第二图像中的第二图像元素相对于第二适应模型的空间位置，在第一图像和第二图像中确定。由于该模型具有固定的拓扑结构，所以即使第一和第二图像显示具有如心脏等复杂属性的对象，因此可以相对可靠地找到相应的图像元素，从而提高注册质量。

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