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1. 发明申请

US20140155351A1 PROCESS FOR THE PREPARATION OF PRASUGREL AND SEVERAL NOVEL CRYSTALLINE FORMS OF PRASUGREL HYDROCHLORIDE 有权
标题翻译：前体化合物的预处理和几种新型结晶形式的制备方法
公开(公告)号：US20140155351A1
公开(公告)日：2014-06-05
申请号：US14123109
申请日：2012-06-21
申请人： Lijun Li , Hailong Wang , Zhongqing Wang
发明人： Lijun Li , Hailong Wang , Zhongqing Wang
IPC分类号： C07F7/18 , C07D495/04
CPC分类号： C07F7/188 , C07D495/04 , C07F7/1804
摘要： Disclosed herein are a process or method for the preparation of prasugrel and several novel crystalline forms of prasugrel hydrochloride. The process comprises preparation of prasugrel by acetylation in solvents which have low boiling point and/or low toxicity, and the process not only avoids using solvents which have high boiling point and/or high toxicity such as toluene, acetonitrile and so on, but also resolves the problem about thermal instability of prasugrel, and the loss of prasugrel is reduced, as well as the yield is raised. The yield of prasugrel is higher than 85% and the purity is higher than 99.5%. The process can prepare prasugrel and its pharmaceutically acceptable salts. The novel crystalline forms of prasugrel hydrochloride are crystalline form H1, H2 and H3, and their performance in oral absorbability, activating metabolism and inhibiting platelet aggregation is excellent. They have a low toxicity and good thermal stability, and are applicable to the preparation of a drug for preventing or treating diseases caused by thrombosis or embolism.
摘要翻译：本文公开了制备普拉格雷和几种新型的普拉格雷盐酸盐结晶形式的方法或方法。该方法包括通过在低沸点和/或低毒性的溶剂中乙酰化制备普拉格雷，并且该方法不仅避免使用具有高沸点和/或高毒性的溶剂如甲苯，乙腈等，而且还可以解决普拉格雷热不稳定问题，降低普拉格雷的损失，提高产量。普拉格雷的产量高于85％，纯度高于99.5％。该方法可以制备普拉格雷及其药学上可接受的盐。普拉格雷盐酸盐的新型结晶形式是H1，H2和H3结晶，口服吸收性能，活化代谢和抑制血小板聚集性能优异。它们具有低毒性和良好的热稳定性，适用于预防或治疗由血栓形成或栓塞引起的疾病的药物的制备。

2. 发明授权

US08937053B2 Process for the preparation of prasugrel and several novel crystalline forms of prasugrel hydrochloride 有权
标题翻译：制备普拉格雷和几种新型的普拉格雷盐酸盐结晶形式的方法
公开(公告)号：US08937053B2
公开(公告)日：2015-01-20
申请号：US14123109
申请日：2012-06-21
申请人： Lijun Li , Hailong Wang , Zhongqing Wang
发明人： Lijun Li , Hailong Wang , Zhongqing Wang
IPC分类号： C07D491/02 , A61K31/695 , C07F7/18 , C07D495/04
CPC分类号： C07F7/188 , C07D495/04 , C07F7/1804
摘要： Disclosed herein are a process or method for the preparation of prasugrel and several novel crystalline forms of prasugrel hydrochloride. The process comprises preparation of prasugrel by acetylation in solvents which have low boiling point and/or low toxicity, and the process not only avoids using solvents which have high boiling point and/or high toxicity such as toluene, acetonitrile and so on, but also resolves the problem about thermal instability of prasugrel, and the loss of prasugrel is reduced, as well as the yield is raised. The yield of prasugrel is higher than 85% and the purity is higher than 99.5%. The process can prepare prasugrel and its pharmaceutically acceptable salts. The novel crystalline forms of prasugrel hydrochloride are crystalline form H1, H2 and H3, and their performance in oral absorbability, activating metabolism and inhibiting platelet aggregation is excellent. They have a low toxicity and good thermal stability, and are applicable to the preparation of a drug for preventing or treating diseases caused by thrombosis or embolism.
摘要翻译：本文公开了制备普拉格雷和几种新型的普拉格雷盐酸盐结晶形式的方法或方法。该方法包括通过在低沸点和/或低毒性的溶剂中乙酰化制备普拉格雷，并且该方法不仅避免使用具有高沸点和/或高毒性的溶剂如甲苯，乙腈等，而且还解决普拉格雷热不稳定问题，降低普拉格雷的损失，提高产量。普拉格雷的产量高于85％，纯度高于99.5％。该方法可以制备普拉格雷及其药学上可接受的盐。普拉格雷盐酸盐的新型结晶形式是H1，H2和H3结晶，口服吸收，活化代谢和抑制血小板聚集性能优良。它们具有低毒性和良好的热稳定性，适用于预防或治疗由血栓形成或栓塞引起的疾病的药物的制备。

3. 发明申请

US20100247111A1 OPTICAL RELAY SYSTEM AND METHOD 失效
标题翻译：光学继电器系统和方法
公开(公告)号：US20100247111A1
公开(公告)日：2010-09-30
申请号：US12815137
申请日：2010-06-14
申请人： Lijun Li , Qianjin Xiong
发明人： Lijun Li , Qianjin Xiong
IPC分类号： H04B10/00
CPC分类号： H04B10/299
摘要： An optical relay system is provided, which includes a first optical signal distribution device (101), a phase detection device (103), an amplitude regeneration device (102), and a phase regeneration and load device (104). An optical relay method is further provided, which includes the following steps. A received input signal is divided into two paths; phase information of one path of the input signal is extracted, and is converted to an amplitude modulated signal; an amplitude of the other path of the input signal is restored, so as to generate an amplitude regenerated signal; a phase is loaded on the amplitude regenerated signal by using the amplitude modulated signal, so as to generate a phase regenerated signal. The system and method eliminate a phase noise of the signal in a transmission process, improve a transmission performance of the signal, and realize a simple implementation method.
摘要翻译：提供一种光中继系统，其包括第一光信号分配装置（101），相位检测装置（103），振幅再生装置（102）和相位再生和装载装置（104）。还提供了一种光中继方法，其包括以下步骤。接收到的输入信号被分成两条路径; 提取输入信号的一个路径的相位信息，并将其转换为幅度调制信号; 输入信号的另一路径的幅度被恢复，以产生振幅再生信号; 通过使用幅度调制信号在幅度再生信号上加载相位，以产生相位再生信号。该系统和方法消除了传输过程中信号的相位噪声，提高了信号的传输性能，实现了一种简单的实现方法。

4. 发明授权

US08229298B2 Method and device for detecting dispersion, optical signal transmission system 有权
标题翻译：检测色散的方法和装置，光信号传输系统
公开(公告)号：US08229298B2
公开(公告)日：2012-07-24
申请号：US12269502
申请日：2008-11-12
申请人： Yue Liu , Lijun Li , Zhihui Tao , Wei Fu
发明人： Yue Liu , Lijun Li , Zhihui Tao , Wei Fu
IPC分类号： H04B10/08
CPC分类号： H04B10/07951
摘要： The present invention discloses a method for detecting dispersion, overcoming disadvantages of complex configuration and insensitivity to a tiny dispersion of the method and device for detecting dispersion in the prior art. The inventive method includes: obtaining a signal within a predetermined bandwidth range from an optical signal received; obtaining an operated value of power via an operation on the signal within the predetermined bandwidth range; and obtaining amount of system dispersion according to a corresponding relation between the operated value of power and the amount of system dispersion. A device for detecting dispersion is disclosed, including a photoelectric filter operational unit and a processing unit, where an output of the photoelectric filter operational unit is connected to an input of the processing unit. The device for detecting dispersion of the present invention is applicable to an adaptive dispersion compensation system. An optical signal transmission system is further disclosed.
摘要翻译：本发明公开了一种检测色散的方法，克服了现有技术中用于检测色散的方法和装置的微分散的复杂配置和不敏感的缺点。本发明的方法包括：从接收的光信号获得在预定带宽范围内的信号; 通过对所述预定带宽范围内的信号进行操作来获得功率的操作值; 并根据操作的功率值和系统色散量之间的对应关系获得系统色散量。公开了一种用于检测色散的装置，包括光电过滤器操作单元和处理单元，其中光电过滤器操作单元的输出连接到处理单元的输入。用于检测本发明的色散的装置可应用于自适应色散补偿系统。进一步公开了一种光信号传输系统。

5. 发明申请

US20050210110A1 Portable information terminal and computer software 审中-公开
标题翻译：便携式信息终端和计算机软件
公开(公告)号：US20050210110A1
公开(公告)日：2005-09-22
申请号：US10901055
申请日：2004-07-29
申请人： Lijun Li
发明人： Lijun Li
IPC分类号： G06F13/00 , G06F15/16 , H04B7/26 , H04L12/58 , H04L29/08 , H04M1/725 , H04M11/00 , H04Q7/34
CPC分类号： H04L67/18 , H04L51/38 , H04M1/72552 , H04M2250/10
摘要： A portable information terminal performs current position detection by detecting the current position of a user based on position information received from an artificial satellite and position information received from a base station; A position information URL indicative of the current position detected by the current position detection is acquired from a host computer; A processing of writing and editing mail is carried out; and the position information URL is inserted into the mail text being edited as position information, A plurality of tasks can be processed simultaneously; for example, the processing of the current position detection and the processing of the URL acquisition each consist of two or more tasks, and mail is written and edited in response to the operation of a user during the processing of these tasks.
摘要翻译：便携式信息终端根据从人造卫星接收的位置信息和从基站接收到的位置信息，检测用户的当前位置来执行当前位置检测; 从主机获取指示当前位置检测检测到的当前位置的位置信息URL; 执行写入和编辑邮件的处理; 并将位置信息URL插入被编辑的邮件文本中作为位置信息。可以同时处理多个任务; 例如，当前位置检测的处理和URL获取的处理各自包括两个或更多个任务，并且在处理这些任务期间响应于用户的操作来写入和编辑邮件。

6. 发明授权

US11535423B1 Storage box and storage rack 有权
公开(公告)号：US11535423B1
公开(公告)日：2022-12-27
申请号：US17523921
申请日：2021-11-11
申请人： Lijun Li
发明人： Lijun Li
IPC分类号： B65D21/02 , B62B3/00
摘要： The present disclosure provides a storage box, including a bottom, a first side wall, a second side wall, a third side wall and a fourth side wall. The first side wall, the second side wall, the third side wall and the fourth side wall sequentially surround the bottom. The first side wall is parallel to the third side wall, the second side wall is parallel to the fourth side wall, the first side wall is perpendicular to the second side wall, a first notch is disposed on the first side wall, a second notch is disposed on the second side wall, a width of the first notch is larger than or equal to a thickness of the second side wall, a width of the second notch is larger than or equal to a thickness of the first side wall.

7. 发明授权

US08229299B2 Method and device for detecting dispersion, optical signal transmission system 有权
公开(公告)号：US08229299B2
公开(公告)日：2012-07-24
申请号：US13253744
申请日：2011-10-05
申请人： Yue Liu , Lijun Li , Zhihui Tao , Wei Fu
发明人： Yue Liu , Lijun Li , Zhihui Tao , Wei Fu
IPC分类号： H04B10/08
CPC分类号： H04B10/07951
摘要： The present invention discloses a method for detecting dispersion, overcoming disadvantages of complex configuration and insensitivity to a tiny dispersion of the method and device for detecting dispersion in the prior art. The inventive method includes: obtaining a signal within a predetermined bandwidth range from an optical signal received; obtaining an operated value of power via an operation on the signal within the predetermined bandwidth range; and obtaining amount of system dispersion according to a corresponding relation between the operated value of power and the amount of system dispersion. A device for detecting dispersion is disclosed, including a photoelectric filter operational unit and a processing unit, where an output of the photoelectric filter operational unit is connected to an input of the processing unit. The device for detecting dispersion of the present invention is applicable to an adaptive dispersion compensation system. An optical signal transmission system is further disclosed.

8. 发明授权

US08538274B2 Optical relay system and method 失效
标题翻译：光中继系统及方法
公开(公告)号：US08538274B2
公开(公告)日：2013-09-17
申请号：US12815137
申请日：2010-06-14
申请人： Lijun Li , Qianjin Xiong
发明人： Lijun Li , Qianjin Xiong
IPC分类号： H04B10/02
CPC分类号： H04B10/299
摘要： An optical relay system is provided, which includes a first optical signal distribution device (101), a phase detection device (103), an amplitude regeneration device (102), and a phase regeneration and load device (104). An optical relay method is further provided, which includes the following steps. A received input signal is divided into two paths; phase information of one path of the input signal is extracted, and is converted to an amplitude modulated signal; an amplitude of the other path of the input signal is restored, so as to generate an amplitude regenerated signal; a phase is loaded on the amplitude regenerated signal by using the amplitude modulated signal, so as to generate a phase regenerated signal. The system and method eliminate a phase noise of the signal in a transmission process, improve a transmission performance of the signal, and realize a simple implementation method.
摘要翻译：提供一种光中继系统，其包括第一光信号分配装置（101），相位检测装置（103），振幅再生装置（102）和相位再生和装载装置（104）。还提供了一种光中继方法，其包括以下步骤。接收到的输入信号被分成两条路径; 提取输入信号的一个路径的相位信息，并将其转换为幅度调制信号; 输入信号的另一路径的幅度被恢复，以产生振幅再生信号; 通过使用幅度调制信号在幅度再生信号上加载相位，以产生相位再生信号。该系统和方法消除了传输过程中信号的相位噪声，提高了信号的传输性能，实现了一种简单的实现方法。

9. 发明公开

US20230309693A1 STORAGE RACK 审中-公开
公开(公告)号：US20230309693A1
公开(公告)日：2023-10-05
申请号：US17719399
申请日：2022-04-13
申请人： LIJUN LI
发明人： Lijun Li , FENGYU ZHOU
IPC分类号： A47B88/40 , A47B88/90
CPC分类号： A47B88/402 , A47B88/90
摘要： A storage rack includes a bottom storage box, a top storage box, a bottom sliding seat, a top sliding seat, and support rods. The bottom sliding seat and the top sliding seat include mounting holes. Each of the mounting holes is configured to mount one end of a corresponding support rod. The bottom sliding seat and the top sliding seat are detachably connected with the support rods. The bottom storage box is slidable on the bottom sliding seat and is removable from the bottom sliding seat. The top storage box is slidable on the top sliding seat and is removable from the top sliding seat. The top storage box has a first storage space. The bottom storage box is receivable in the first storage space of the top storage box.

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