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1. 发明申请

US20130344619A1 GLUCOSE SENSOR 审中-公开
标题翻译：葡萄糖传感器
公开(公告)号：US20130344619A1
公开(公告)日：2013-12-26
申请号：US13686760
申请日：2012-11-27
申请人： LIGHTSHIP MEDICAL LIMITED
发明人： Barry Colin Crane , William Paterson , Nicholas Paul Barwell , Peter Edgley
IPC分类号： G01N33/66 , A61B5/1459 , A61B5/1473 , A61B5/145
CPC分类号： G01N33/66 , A61B5/14532 , A61B5/1459 , A61B5/1473 , G01N21/6408 , G01N21/6428 , G01N21/7703 , G01N27/3271 , G01N2021/6432 , G01N2021/6434 , G01N2021/6441 , G01N2021/6484 , G01N2021/772 , G01N2021/773 , G01N2021/7786 , G01N2021/7793
摘要： A method of quantifying the amount of glucose in a sample is provided herein that may further comprise an interferent such as mannitol. At least two measurements are obtained using measurement methods that differ in their sensitivity to the amount of interferent in the sample, thus enabling the results to be compared to determine whether any interferent is present in the sample. A glucose sensor for carrying out a method described herein is also provided
摘要翻译：本文提供了定量样品中葡萄糖量的方法，其可以进一步包含诸如甘露醇之类的干扰物。使用测量方法获得至少两个测量值，这些测量方法的灵敏度与样品中干扰物的数量不同，从而使结果能够比较，以确定样品中是否存在任何干扰物。还提供了用于执行本文所述的方法的葡萄糖传感器

2. 发明授权

US08607612B2 Sensor calibration 有权
标题翻译：传感器校准
公开(公告)号：US08607612B2
公开(公告)日：2013-12-17
申请号：US13686484
申请日：2012-11-27
申请人： Lightship Medical Limited
发明人： Nicholas Paul Barwell , Peter Edgley , Alasdair Allan Mackenzie , William Paterson , Barry Colin Crane
IPC分类号： G01K15/00 , G01N33/66 , G01N33/543
CPC分类号： G01K15/005 , G01N33/5438 , G01N33/582 , G01N33/66
摘要： A method of calibrating a reversible-binding sensor for detecting an analyte includes: (i) varying the temperature of a first calibration solution from a first temperature (T1) to a second temperature (T2) while the first calibration solution is in contact with a sensing region of the sensor; (ii) determining the sensor output for the first calibration solution as a function of temperature; (iii) varying the temperature of a second calibration solution from a third temperature (T3) to a fourth temperature (T4) while the second calibration solution is in contact with the sensing region, the second calibration solution having a concentration of analyte which is different from that of the first calibration solution; (iv) determining the sensor output for the second calibration solution as a function of temperature; and (v) using the determined sensor output from steps (ii) and (iv) to calibrate the sensor.
摘要翻译：校准用于检测分析物的可逆结合传感器的方法包括：（i）将第一校准溶液的温度从第一温度（T1）改变到第二温度（T2），同时第一校准溶液与传感器的感测区域; （ii）确定作为温度的函数的第一校准溶液的传感器输出; （iii）当第二校准溶液与感测区域接触时，将第二校准溶液的温度从第三温度（T3）变化到第四温度（T4），第二校准溶液具有不同的分析物浓度从第一个校准溶液的; （iv）确定作为温度的函数的第二校准溶液的传感器输出; 和（v）使用来自步骤（ii）和（iv）的确定的传感器输出来校准传感器。

3. 发明申请

US20180306802A1 GLUCOSE SENSOR 审中-公开
公开(公告)号：US20180306802A1
公开(公告)日：2018-10-25
申请号：US15881489
申请日：2018-01-26
申请人： Lightship Medical Limited
发明人： Barry Colin Crane , William Paterson , Nicholas Paul Barwell , Peter Edgley
IPC分类号： G01N33/66 , A61B5/1459 , A61B5/1473 , A61B5/145 , G01N21/64 , G01N21/77 , G01N27/327
CPC分类号： G01N33/66 , A61B5/14532 , A61B5/1459 , A61B5/1473 , G01N21/6408 , G01N21/6428 , G01N21/7703 , G01N27/3271 , G01N2021/6432 , G01N2021/6434 , G01N2021/6441 , G01N2021/6484 , G01N2021/772 , G01N2021/773 , G01N2021/7786 , G01N2021/7793
摘要： A method of quantifying the amount of glucose in a sample is provided herein that may further comprise an interferent such as mannitol. At least two measurements are obtained using measurement methods that differ in their sensitivity to the amount of interferent in the sample, thus enabling the results to be compared to determine whether any interferent is present in the sample. A glucose sensor for carrying out a method described herein is also provided

4. 发明申请

US20130083820A1 Sensor Calibration 有权
标题翻译：传感器校准
公开(公告)号：US20130083820A1
公开(公告)日：2013-04-04
申请号：US13686484
申请日：2012-11-27
申请人： Lightship Medical Limited
发明人： Nicholas Paul Barwell , Peter Edgley , Alasdair Allan Mackenzie , William Paterson , Barry Colin Crane
IPC分类号： G01K15/00
CPC分类号： G01K15/005 , G01N33/5438 , G01N33/582 , G01N33/66
摘要： A method of calibrating a reversible-binding sensor for detecting an analyte includes: (i) varying the temperature of a first calibration solution from a first temperature (T1) to a second temperature (T2) while the first calibration solution is in contact with a sensing region of the sensor; (ii) determining the sensor output for the first calibration solution as a function of temperature; (iii) varying the temperature of a second calibration solution from a third temperature (T3) to a fourth temperature (T4) while the second calibration solution is in contact with the sensing region, the second calibration solution having a concentration of analyte which is different from that of the first calibration solution; (iv) determining the sensor output for the second calibration solution as a function of temperature; and (v) using the determined sensor output from steps (ii) and (iv) to calibrate the sensor.
摘要翻译：校准用于检测分析物的可逆结合传感器的方法包括：（i）将第一校准溶液的温度从第一温度（T1）改变到第二温度（T2），同时第一校准溶液与传感器的感测区域; （ii）确定作为温度的函数的第一校准溶液的传感器输出; （iii）在第二校准溶液与感测区域接触的同时将第二校准溶液的温度从第三温度（T3）变化到第四温度（T4），第二校准溶液具有不同的分析物浓度从第一个校准溶液的; （iv）确定作为温度的函数的第二校准溶液的传感器输出; 和（v）使用来自步骤（ii）和（iv）的确定的传感器输出来校准传感器。

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