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1. 发明申请

US20050232923A1 Methods and compositions for treating MCP-1 related pathologies 审中-公开
标题翻译：用于治疗MCP-1相关病变的方法和组合物
公开(公告)号：US20050232923A1
公开(公告)日：2005-10-20
申请号：US10981936
申请日：2004-11-05
申请人： Li Yan , Marian Nakada , Anuk Das
发明人： Li Yan , Marian Nakada , Anuk Das
IPC分类号： A61K20060101 , A61K31/137 , A61K31/445 , A61K31/473 , A61K31/573 , A61K38/18 , A61K38/54 , A61K39/395 , A61K45/06 , C07K16/24
CPC分类号： A61K31/573 , A61K31/137 , A61K31/445 , A61K31/473 , A61K38/00 , A61K39/395 , A61K45/06 , A61K2039/505 , C07K16/24 , C07K2317/21 , C07K2317/73 , A61K2300/00
摘要： The present invention relates to methods for treating at least one MCP-1 related condition or pathology, including therapeutic compositions, methods and devices.
摘要翻译：本发明涉及用于治疗至少一种MCP-1相关病症或病理学的方法，包括治疗组合物，方法和装置。

2. 发明申请

US20050136451A1 Hypoxia responsive human CNGH 0002 genes and polypeptides 审中-公开
标题翻译：低氧反应性人CNGH 0002基因和多肽
公开(公告)号：US20050136451A1
公开(公告)日：2005-06-23
申请号：US10957503
申请日：2004-10-01
申请人： Li Yan , Chris Huang , Prabakaran Kesavan , Katherine Li , Marian Nakada
发明人： Li Yan , Chris Huang , Prabakaran Kesavan , Katherine Li , Marian Nakada
IPC分类号： C07H21/04 , C07K14/47 , C12N20060101 , C12N9/02 , C12Q1/68
CPC分类号： C07K14/47
摘要： The invention provides isolated nucleic acids encoding a variety of nucleic acids and proteins having diagnostic, preventive, therapeutic, and other uses. These nucleic acids and proteins are useful for diagnosis, prevention, and therapy of a number of human and other animal disorders. The invention also provides antisense nucleic acids molecules, expression vectors containing the nucleic acids molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acids molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided. The nucleic acids and polypeptides of the present invention are useful as modulating agents in regulating a variety of cellular processes.
摘要翻译：本发明提供编码具有诊断，预防，治疗和其它用途的各种核酸和蛋白质的分离的核酸。这些核酸和蛋白质可用于诊断，预防和治疗许多人类和其他动物疾病。本发明还提供了反义核酸分子，含有本发明的核酸分子的表达载体，已经引入了表达载体的宿主细胞，以及其中引入了本发明的核酸分子的非人转基因动物，或中断了本发明还进一步提供分离的多肽，融合多肽，抗原肽和抗体。还提供了利用本发明组合物的诊断，筛选和治疗方法。本发明的核酸和多肽可用作调节各种细胞过程的调节剂。

3. 发明申请

US20050214302A1 Use of emmprin antagonists for the treatment of diseases associated with excessive angiogenesis 审中-公开
标题翻译：使用emmprin拮抗剂治疗与过度血管生成相关的疾病
公开(公告)号：US20050214302A1
公开(公告)日：2005-09-29
申请号：US10808699
申请日：2004-03-25
申请人： Marian Nakada , Li Yan , Yi Tang
发明人： Marian Nakada , Li Yan , Yi Tang
IPC分类号： A61K39/395 , C07K16/28
CPC分类号： C07K16/2896 , A61K2039/505 , C07K2317/76
摘要： A method of using EMMPRIN antagonists to treat pathological processes associated with proliferative diseases, such as cancer, by specifically preventing or inhibiting the ability of new tissue to develop a blood supply. The invention more specifically relates to methods of treating such diseases by the use of EMMPRIN antagonists such as antibodies directed toward EMMPRIN, including specified portions or variants, specific for at least one EMMPRIN protein or fragment thereof, in an amount effective to inhibit angiogenesis.
摘要翻译：通过特异性预防或抑制新组织发展血液供应的能力，使用EMMPRIN拮抗剂治疗与增殖性疾病如癌症相关的病理过程的方法。本发明更具体地涉及通过使用有效抑制血管生成的量的EMMPRIN拮抗剂，例如针对EMMPRIN的抗体，包括对至少一种EMMPRIN蛋白或其片段特异性的特定部分或变体来治疗这些疾病的方法。

4. 发明申请

US20050008638A1 CNGH0005 polypeptides, antibodies, compositions, methods and uses 审中-公开
标题翻译： CNGH0005多肽，抗体，组合物，方法和用途
公开(公告)号：US20050008638A1
公开(公告)日：2005-01-13
申请号：US10603313
申请日：2003-06-25
申请人： Jin Lu , Li Yan , Chris Huang , Marian Nakada
发明人： Jin Lu , Li Yan , Chris Huang , Marian Nakada
IPC分类号： A61K38/00 , C07K14/47 , C12Q1/68 , A61K39/395 , C07H21/04 , C07K16/40 , C12N5/06 , C12N9/00 , C12P21/02
CPC分类号： C07K14/4748 , A61K38/00
摘要： The present invention relates to at least one novel CNGH0005 polypeptides, antibodies, including isolated nucleic acids that encode at least one CNGH0005 polypeptide or antibody, CNGH0005 vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
摘要翻译：本发明涉及至少一种新的CNGH0005多肽，抗体，包括编码至少一种CNGH0005多肽或抗体的分离的核酸，CNGH0005载体，宿主细胞，转基因动物或植物，及其制备和使用方法，包括治疗组合物，方法和设备。

5. 发明授权

US09012921B2 Light emitting devices having light coupling layers 有权
标题翻译：具有光耦合层的发光器件
公开(公告)号：US09012921B2
公开(公告)日：2015-04-21
申请号：US13249184
申请日：2011-09-29
申请人： Chao-Kun Lin , Li Yan , Chih-Wei Chuang
发明人： Chao-Kun Lin , Li Yan , Chih-Wei Chuang
IPC分类号： H01L33/32 , H01L33/22 , H01L33/00
CPC分类号： H01L33/0075 , H01L33/0025 , H01L33/0079 , H01L33/10 , H01L33/22 , H01L33/32 , H01L33/38 , H01L33/405 , H01L2924/00 , H01L2924/0002 , H01L2933/0016 , H01L2933/0058
摘要： A light emitting device comprises a first layer of an n-type semiconductor material, a second layer of a p-type semiconductor material, and an active layer between the first layer and the second layer. A light coupling layer is disposed adjacent to one of the first layer and the second layer. In some cases, the light coupling layer is formed by roughening a buffer layer of the light emitting device. The light emitting device includes an electrode in electrical communication with one of the first layer and the second layer through a portion of the light coupling layer.
摘要翻译：发光器件包括n型半导体材料的第一层，p型半导体材料的第二层和在第一层和第二层之间的有源层。光耦合层设置成与第一层和第二层中的一个相邻。在一些情况下，通过使发光器件的缓冲层粗糙化来形成光耦合层。发光器件包括通过光耦合层的一部分与第一层和第二层之一电连通的电极。

6. 发明授权

US08477685B2 Enhanced mobility management at a mobile access gateway 有权
标题翻译：移动接入网关增强移动性管理
公开(公告)号：US08477685B2
公开(公告)日：2013-07-02
申请号：US12512594
申请日：2009-07-30
申请人： Li Yan
发明人： Li Yan
IPC分类号： H04W4/00 , H04W36/00 , H04J3/06 , H04L12/56
CPC分类号： H04L65/105 , H04L65/80 , H04L2212/00 , H04W8/082 , H04W80/045 , H04W80/10
摘要： A method is disclosed that enables the transmission of media and signaling packets in a Proxy Mobile Internet Protocol-based (PMIP-based) network. A mobile access gateway is enhanced to differentiate between different types of packet traffic and to act as a Session Initiation Protocol (SIP) proxy on behalf of a mobile node. For example, the gateway is able to handle quality-of-service-sensitive (QoS-sensitive) traffic such as voice or video media packets differently from QoS-insensitive traffic such as SIP signaling packets. In the case of traffic packets that are not QoS-sensitive, the gateway engages standard PMIPv6 procedure. In the case of traffic packets that are in fact QoS-sensitive, the gateway acts as a SIP proxy for each mobile node attached to it, thereby avoiding tunneling of the packets between the gateway and the mobile node's local mobility anchor, and thereby reducing the amount of delay that affects the packets.
摘要翻译：公开了一种能够在基于代理移动因特网协议（基于PMIP）的网络中传输媒体和信令分组的方法。移动接入网关被增强以区分不同类型的分组业务，并且代表移动节点充当会话发起协议（SIP）代理。例如，网关能够处理诸如语音或视频媒体分组的服务质量敏感（QoS敏感）流量，不同于不敏感的业务，例如SIP信令分组。在不敏感的流量报文的情况下，网关采用标准的PMIPv6过程。在事实上对QoS敏感的业务分组的情况下，网关充当连接到其的每个移动节点的SIP代理，从而避免在网关与移动节点的本地移动锚之间的分组隧穿，从而减少影响数据包的延迟量。

7. 发明授权

US08407568B2 Method and system for a soft-output Nordstrom-Robinson decoder 有权
标题翻译：软输出Nordstrom-Robinson解码器的方法和系统
公开(公告)号：US08407568B2
公开(公告)日：2013-03-26
申请号：US12551102
申请日：2009-08-31
申请人： Zvi Bernstein , Mike Grimwood , Li Yan
发明人： Zvi Bernstein , Mike Grimwood , Li Yan
IPC分类号： H03M13/45
CPC分类号： H04L25/067 , H04L27/38
摘要： Aspects of a method and system for a method and system for a soft output Nordstrom-Robinson (NR) decoder may include one or more processors and/or circuits that are operable to more efficiently compute cross correlation values for a received soft output word based on a NR codebook in comparison to brute force computation approaches. Log likelihood ratios may be computed for each information bit corresponding to the received soft output word by determining corresponding maximum cross correlation values.
摘要翻译：用于软输出Nordstrom-Robinson（NR）解码器的方法和系统的方法和系统的方面可以包括一个或多个处理器和/或电路，其可操作以更有效地计算所接收的软输出字的互相关值，基于与暴力计算方法相比，NR码本。可以通过确定对应的最大互相关值来计算对应于所接收的软输出字的每个信息位的对数似然比。

8. 发明申请

US20120005143A1 Model and algorithm for automated item generator of the graphic intelligence test 审中-公开
标题翻译：图形智能测试自动化项目生成器的模型和算法
公开(公告)号：US20120005143A1
公开(公告)日：2012-01-05
申请号：US12927852
申请日：2010-11-29
申请人： JinShuo Liu , Li Yan , Juan Deng , Junxing Yang , Yang yang Lu , Yu Long Zhang , Xin Chen
发明人： JinShuo Liu , Li Yan , Juan Deng , Junxing Yang , Yang yang Lu , Yu Long Zhang , Xin Chen
IPC分类号： G06N5/02
CPC分类号： G09B7/02
摘要： A model for automated item generator of the graphic intelligence test solves the tremendous time consuming problem for manually devising the graph intelligence item. At the same time, the invention can automated generate more complicated, more transformations and better layout graph for intelligence test, which are hard to predict. The model utilizes the 12 branch tree as the expressing pattern of matrix graph item, and 8 branch trees as the expressing pattern of series graph item. The automated generating item methods have been presented, and the difficulty of the item has also been validated with the similarity of the optional answers and difficulties of the rules and complexity of the sub-graph. The best feature of the model is that a big amount of the graph item for intelligence test can be generated at one time by the computer, instead of manually devising the matrix graph or series graph for intelligence test. With the model, the online intelligence test platform can update the test database automatically, thus the intelligence and the ability of the examinee can be evaluated breaking through the barrier of the language, culture and education background.
摘要翻译：图形智能测试的自动化项目生成器的模型解决了手动设计图形智能项目的巨大耗时问题。同时，本发明可以自动生成更复杂，更多的转换和更好的智能测试布局图，难以预测。该模型利用12个分支树作为矩阵图项的表达模式，8个分支树作为系列图项的表达模式。已经提出了自动生成项目方法，并且项目的难度也经过了可选答案的相似性和规则的难度和子图的复杂性的验证。该模型的最大特点是可以通过计算机一次生成大量用于智能测试的图形项目，而不是手动设计用于智能测试的矩阵图或系列图。通过该模型，在线智能测试平台可以自动更新测试数据库，从而通过语言，文化和教育背景的障碍来评估学生的智力和能力。

9. 发明授权

US5629736A Coded domain picture composition for multimedia communications systems 失效
标题翻译：用于多媒体通信系统的编码域图像组合
公开(公告)号：US5629736A
公开(公告)日：1997-05-13
申请号：US332985
申请日：1994-11-01
申请人： Barin G. Haskell , Li Yan
发明人： Barin G. Haskell , Li Yan
IPC分类号： H04N7/08 , H04N7/081 , H04N7/15 , H04N7/26 , H04N7/30 , H04N7/50 , H04N21/2365 , H04N21/434 , H04N7/12 , H04N11/02
CPC分类号： H04N21/2365 , H04N19/115 , H04N19/124 , H04N19/152 , H04N19/159 , H04N19/176 , H04N19/18 , H04N19/184 , H04N19/40 , H04N19/48 , H04N19/61 , H04N19/90 , H04N21/4347 , H04N7/152 , H04N19/146
摘要： Video composition techniques are disclosed for processing video information from a plurality of sources to provide a video image having a plurality of rectangular regions. Each rectangular region displays video information from a specific one of the plurality of video sources. The video information from each video source is in the form of an incoming digital bit stream. The digital bit stream from a first video source has a first bit rate, and the digital bit stream from a second video source has a second bit rate where the first bit rate may or may not be equal to the second bit rate. The incoming digital bit streams are fed to a rate matching circuit which converts all incoming digital bit streams to a common bit rate. The output of the rate matching circuit is fed to a synchronization arid multiplexer circuit which places video information from specific digital bit streams into corresponding rectangular regions of a composite video image.
摘要翻译：公开了用于处理来自多个源的视频信息以提供具有多个矩形区域的视频图像的视频合成技术。每个矩形区域显示来自多个视频源中的特定一个的视频信息。来自每个视频源的视频信息是输入数字比特流的形式。来自第一视频源的数字比特流具有第一比特率，并且来自第二视频源的数字比特流具有第二比特率，其中第一比特率可以或可以不等于第二比特率。输入的数字比特流被馈送到速率匹配电路，其将所有输入的数字比特流转换成公共比特率。速率匹配电路的输出被馈送到同步和多路复用器电路，其将来自特定数字比特流的视频信息放入到复合视频图像的相应矩形区域中。

10. 发明授权

US08664679B2 Light emitting devices having light coupling layers with recessed electrodes 有权
标题翻译：具有具有凹陷电极的光耦合层的发光器件
公开(公告)号：US08664679B2
公开(公告)日：2014-03-04
申请号：US13249196
申请日：2011-09-29
申请人： Li Yan , Chao-Kun Lin , Chih-Wei Chuang
发明人： Li Yan , Chao-Kun Lin , Chih-Wei Chuang
IPC分类号： H01L33/58
CPC分类号： H01L33/30 , H01L33/10 , H01L33/22 , H01L33/32 , H01L33/382 , H01L33/58 , H01L2924/0002 , H01L2924/00
摘要： A light emitting device comprises a first layer of an n-type semiconductor material, a second layer of a p-type semiconductor material, and an active layer between the first layer and the second layer. A light coupling structure is disposed adjacent to one of the first layer and the second layer. In some cases, the light coupling structure is disposed adjacent to the first layer. An orifice formed in the light coupling structure extends to the first layer. An electrode formed in the orifice is in electrical communication with the first layer.
摘要翻译：发光器件包括n型半导体材料的第一层，p型半导体材料的第二层和在第一层和第二层之间的有源层。光耦合结构设置成与第一层和第二层之一相邻。在一些情况下，光耦合结构设置成与第一层相邻。形成在光耦合结构中的孔口延伸到第一层。形成在孔中的电极与第一层电连通。

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