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1. 发明授权

US06672172B2 Triggered flow measurement 有权
标题翻译：触发流量测量
公开(公告)号：US06672172B2
公开(公告)日：2004-01-06
申请号：US09771703
申请日：2001-01-30
申请人： Sauli Tulkki , Leif Smith
发明人： Sauli Tulkki , Leif Smith
IPC分类号： G01P518
CPC分类号： A61B5/028
摘要： When a bolus dose of cold saline is injected into a catheter where a wire, carrying a sensor unit and electrical leads for signal transmission, is located, the lead resistance is affected by the cold saline thereby altering the resistivity. However, by countering this effect and measuring the change needed to affect this countermeasure, a resistance variation curve can be generated. An accurate starting point for the determination of a transit time can be derived from the curve. Using conventional flow measurement calculations with the accurate starting point yields a better understanding of the flow profile in an artery based on the transit time.
摘要翻译：当将大剂量的冷盐水注射到导管中时，导管中携带传感器单元和电气引线用于信号传导，导线电阻受冷盐水影响，从而改变电阻率。然而，通过抵消这种影响并测量影响该对策所需的变化，可以产生电阻变化曲线。可以从曲线导出确定通行时间的准确起点。使用具有准确起点的常规流量测量计算可以更好地了解基于运输时间的动脉中的流动特征。

2. 发明申请

US20070220986A1 Pressure sensor 有权
标题翻译：压力传感器
公开(公告)号：US20070220986A1
公开(公告)日：2007-09-27
申请号：US11384817
申请日：2006-03-21
申请人： Leif Smith , Sauli Tulkki
发明人： Leif Smith , Sauli Tulkki
IPC分类号： G01L9/06
CPC分类号： G01L9/0025 , B60C23/0408 , G01L9/008
摘要： A sensor and insertion assembly 2 is used for intravascular measurement of pressure in a living body. The assembly includes a sensor chip 6 having a substrate body 8 with a recess covered by a pressure sensitive film 10 thereby forming a cavity 12. A piezoelectric element, preferably in the form of a piezoelectric film 14, is arranged in connection with the pressure sensitive film, and energy is applied to the piezoelectric element such that acoustic waves are generated in the element. The piezoelectric element is arranged to generate an output signal, representing the pressure at the film, in dependence on the measured properties of the acoustic waves related to the deflection of the pressure sensitive film.
摘要翻译：传感器和插入组件2用于血管内测量活体内的压力。组件包括传感器芯片6，传感器芯片6具有衬底本体8，衬底本体8具有被压敏薄膜10覆盖的凹部，从而形成空腔12.压电元件优选为压电薄膜14，与压力敏感膜和能量被施加到压电元件，使得在该元件中产生声波。压电元件被布置成根据与压敏膜的偏转相关的声波的测量特性，产生表示膜上的压力的输出信号。

3. 发明授权

US07331236B2 Pressure sensor 有权
标题翻译：压力传感器
公开(公告)号：US07331236B2
公开(公告)日：2008-02-19
申请号：US11384817
申请日：2006-03-21
申请人： Leif Smith , Sauli Tulkki
发明人： Leif Smith , Sauli Tulkki
IPC分类号： G01L7/00
CPC分类号： G01L9/0025 , B60C23/0408 , G01L9/008
摘要： A sensor and insertion assembly 2 is used for intravascular measurement of pressure in a living body. The assembly includes, a sensor chip 6 having a substrate body 8 with a recess covered by a pressure sensitive film 10 thereby forming a cavity 12. A piezoelectric element, preferably in the form of a piezoelectric film 14, is arranged in connection with the pressure sensitive film, and energy is applied to the piezoelectric element such that acoustic waves are generated in the element. The piezoelectric element is arranged to generate an output signal, representing the pressure at the film, in dependence on the measured properties of the acoustic waves related to the deflection of the pressure sensitive film.
摘要翻译：传感器和插入组件2用于血管内测量活体内的压力。组件包括传感器芯片6，传感器芯片6具有衬底本体8，衬底本体8具有由压敏膜10覆盖的凹部，从而形成空腔12。优选以压电膜14的形式的压电元件与压敏膜连接设置，并且能量被施加到压电元件，使得在该元件中产生声波。压电元件被布置成根据与压敏膜的偏转相关的声波的测量特性，产生表示膜上的压力的输出信号。

4. 发明申请

US20070255145A1 Sensor and guide wire assembly 审中-公开
标题翻译：传感器和导丝组件
公开(公告)号：US20070255145A1
公开(公告)日：2007-11-01
申请号：US11413122
申请日：2006-04-28
申请人： Leif Smith , Par Malmborg , Erik During
发明人： Leif Smith , Par Malmborg , Erik During
IPC分类号： A61B5/02
CPC分类号： A61B5/0215 , A61B5/6851 , A61M25/09
摘要： A sensor and guide wire assembly (21; 41) for intravascular measurements of a physiological variable in a living body, comprises a sensor element (22; 42) and a sensor guide wire (23; 43) comprising a core wire (28; 48) and at least one signal transmitting cable (31; 51) connected to the sensor element, wherein a polymer layer (27; 47) is provided which encloses a portion of the core wire and the at least one signal transmitting cable.
摘要翻译：一种传感器和导丝组件（21; 41），用于血管内测量活体中的生理变量，包括传感器元件（22; 42）和传感器导丝（23; 43），其包括芯线（28; 48 ）和连接到传感器元件的至少一个信号传输电缆（31; 51），其中提供聚合物层（27; 47），其包围芯线的一部分和至少一个信号传输电缆。

5. 发明授权

US07998089B2 Method of making a guide wire based assembly and reusing an energy source 有权
标题翻译：制造基于导丝的组件和重新使用能量源的方法
公开(公告)号：US07998089B2
公开(公告)日：2011-08-16
申请号：US11937123
申请日：2007-11-08
申请人： Leif Smith
发明人： Leif Smith
IPC分类号： A61B5/00 , A61B5/02 , A61M25/00
CPC分类号： A61B5/0215 , A61B5/0002 , A61B5/6851 , A61B2560/0214 , A61B2560/0443 , A61B2562/225 , A61M25/09 , H01R13/622 , H01R13/6683 , H01R13/6691 , H01R24/66 , H01R24/76 , H01R2103/00
摘要： A transmitter unit with a detachable energy source is provided for a sensor guidewire. The transmitter unit is adapted to be connected to a proximal end of a sensor guidewire provided, at its distal end, with a sensor to measure a physiological parameter inside a patient. In some embodiments, the transmitter unit is adapted to wirelessly communicate by a communication signal with a communication unit, arranged in connection with an external device, in order to transfer measured physiological data to the external device. The detachable energy source can be a battery pack provided with connecting electrical connecting surfaces. Preferably, the connection is protected from penetrating fluids by a protective seal.
摘要翻译：为传感器导丝提供具有可拆卸能量源的发射器单元。发射器单元适于连接到传感器导丝的近端，传感器导丝在其远端处设置有用于测量患者体内生理参数的传感器。在一些实施例中，发射机单元适于通过通信信号与通信单元进行无线通信，该通信单元与外部设备结合地布置，以将测量的生理数据传送到外部设备。可拆卸能源可以是具有连接电连接表面的电池组。优选地，通过保护性密封来保护连接不渗透流体。

6. 发明申请

US20100318000A1 SENSOR GUIDE WIRE 审中-公开
标题翻译：传感器指导线
公开(公告)号：US20100318000A1
公开(公告)日：2010-12-16
申请号：US12739323
申请日：2008-10-24
申请人： Pär Von Malmborg , Leif Smith
发明人： Pär Von Malmborg , Leif Smith
IPC分类号： A61M25/09
CPC分类号： A61M25/09 , A61B5/0215 , A61B5/6851 , A61B2562/028 , A61B2562/222
摘要： The present invention relates to a sensor guide wire for intravascular measurements of physiological variables in a living body, having a proximal shaft region, a flexible region and a distal sensor region. The sensor guide wire comprises, a sensor element provided in the sensor region, for measuring the physiological variable and to generate a sensor signal in response to said variable, a signal transmitting micro cable connected to the sensor element, and running along the sensor guide wire to the shaft region. The guide wire consists of, at least along the length of the flexible region, a guide wire tube that encloses the signal transmitting micro cable.
摘要翻译：本发明涉及一种用于生物体内生理变量血管内测量的传感器导丝，其具有近端轴区域，柔性区域和远端传感器区域。传感器引导线包括设置在传感器区域中的传感器元件，用于测量生理变量并响应于所述变量产生传感器信号，连接到传感器元件的信号传输微型电缆，并沿着传感器导丝到轴区域。引导线至少沿柔性区域的长度由包围信号传输微电缆的导丝管组成。

7. 发明申请

US20090082678A1 Pressure wire assembly 有权
标题翻译：压线组件
公开(公告)号：US20090082678A1
公开(公告)日：2009-03-26
申请号：US11902805
申请日：2007-09-25
申请人： Leif Smith
发明人： Leif Smith
IPC分类号： A61B5/0215
CPC分类号： A61B5/0215 , A61B5/6851
摘要： Pressure sensor wire assembly for measuring pressure inside a body of a patient, the assembly comprises a pressure sensor element for measuring pressure and to generate a pressure sensor signal in response of said pressure, and a pressure sensor wire having said pressure sensor element at its distal portion, and adapted to be inserted into the body in order to position the sensor element within the body. In addition is arranged a sensor signal adapting circuitry, being an integrated part of said assembly, wherein the pressure sensor signal is applied to the adapting circuitry that is adapted to automatically generate an output pressure signal, related to the sensor signal, in a standardized format such that the measured pressure is retrievable by an external physiology monitor. The assembly further comprises an external pressure sensor arranged at the assembly to measure the pressure outside the patient's body and to generate external pressure values in dependence thereto, the external pressure values are applied to a pressure compensation means, in the assembly, adapted to generate a compensation value reflecting the external pressure variation during a measurement procedure, wherein the output pressure signal is compensated by said compensation value prior to the output pressure signal being applied to the external physiology monitor.
摘要翻译：用于测量患者体内的压力的压力传感器线组件，所述组件包括用于测量压力并响应于所述压力产生压力传感器信号的压力传感器元件，以及在其远端具有所述压力传感器元件的压力传感器线并且适于插入到身体中以便将传感器元件定位在身体内。另外布置有作为所述组件的集成部分的传感器信号适配电路，其中压力传感器信号被施加到适配电路，其适于以标准化格式自动产生与传感器信号相关的输出压力信号使得测量的压力可通过外部生理学监测器检索。组件还包括布置在组件处的外部压力传感器，用于测量患者身体外部的压力并根据其产生外部压力值，外部压力值被施加到组件中的压力补偿装置，适于产生反映在测量过程期间的外部压力变化的补偿值，其中在将输出压力信号施加到外部生理学监视器之前，输出压力信号由所述补偿值补偿。

8. 发明申请

US20080319328A1 FEMORAL COMPRESSION DEVICE 有权
标题翻译：有限元压缩装置
公开(公告)号：US20080319328A1
公开(公告)日：2008-12-25
申请号：US11767179
申请日：2007-06-22
申请人： Dan AKERFELDT , Leif Smith , Marie Lindstrom , Tobias Adenmark
发明人： Dan AKERFELDT , Leif Smith , Marie Lindstrom , Tobias Adenmark
IPC分类号： A61B5/0225
CPC分类号： A61B17/135 , A61B2017/00115 , A61B2017/00123
摘要： A femoral compression device (1) for compressive bearing against the femoral artery of a patient, comprising a base plate (2), an inflatable air cushion (4), and an electronic manometer (8) connected to the inflatable air cushion for measurement of the current pressure difference between the pressure prevailing inside the inflatable air cushion and the ambient air pressure. The femoral compression device can further comprise a mechanical device (11; 46) which prevents an air opening leading to the inflatable air cushion from being closed before the manometer is zeroed. In another embodiment, an electronic manometer is provided such that a current characteristic of an electric signal representing the current pressure difference can be compared with a corresponding characteristic which was obtained at zero pressure difference and which was stored in the electronic manometer, wherein the manometer cannot be zeroed as long as the current characteristic deviates more than a predetermined amount from the stored characteristic.
摘要翻译：一种用于抵抗患者股动脉的压缩轴承的股骨压缩装置（1），包括基板（2），可充气气垫（4）和连接到可充气气垫的电子压力计（8），用于测量充气气垫内的压力与周围空气压力之间的当前压力差。股骨压缩装置还可以包括机械装置（11; 46），该机械装置防止在压力计归零之前通向可充气气垫的空气开口被关闭。在另一个实施例中，提供电子压力计，使得可以将表示当前压力差的电信号的电流特性与在零压差下获得并且存储在电子压力计中的相应特性进行比较，其中压力计不能只要电流特性从存储的特性偏离超过预定量就被归零。

9. 发明申请

US20060207335A1 Sensor and guide wire assembly 有权
标题翻译：传感器和导丝组件
公开(公告)号：US20060207335A1
公开(公告)日：2006-09-21
申请号：US11359761
申请日：2006-02-23
申请人： Lars Tenerz , Leif Smith
发明人： Lars Tenerz , Leif Smith
IPC分类号： G01L9/00
CPC分类号： A61M25/09 , A61B5/0215 , A61B5/6851 , A61M2025/0166 , A61M2025/09083 , G01L9/0022 , G01L9/06 , G01L19/142 , G01L19/147 , H01L2224/48091 , H01L2224/48137 , H01L2924/00014
摘要： The invention relates to a sensor (23) adapted for a sensor and guide wire assembly for intravascular measurements in a living body, wherein the sensor (23) comprises a pressure sensitive part (24) and an electronic part (25), said pressure sensitive part (24) comprising a first chip (26) provided with at least one pressure sensitive device (27) and at least one piezoelectric element (35), and said electronic part (25) comprising a second chip (28) provided with at least one electric circuit, and wherein said pressure sensitive part (24) and electronic part (25) are spatially separated from each other and are electrically connected with at least one electrical lead (29).
摘要翻译：本发明涉及一种适用于生物体内用于血管内测量的传感器和导丝组件的传感器（23），其中传感器（23）包括压敏部件（24）和电子部件（25），所述压敏包括设置有至少一个压敏装置（27）和至少一个压电元件（35）的第一芯片（26）的部分（24），并且所述电子部件（25）包括至少设置有第二芯片一个电路，并且其中所述压敏部件（24）和电子部件（25）在空间上彼此分离并且与至少一个电引线（29）电连接。

10. 发明授权

US06477233B1 Miniature x-ray source 失效
标题翻译：微型x射线源
公开(公告)号：US06477233B1
公开(公告)日：2002-11-05
申请号：US09585283
申请日：2000-06-02
申请人： Carolina Ribbing , Pelle Rangsten , Lars Tenerz , Leif Smith , Klas Hjort
发明人： Carolina Ribbing , Pelle Rangsten , Lars Tenerz , Leif Smith , Klas Hjort
IPC分类号： H01J3506
CPC分类号： A61N5/1001 , A61N5/1007 , A61N2005/1008 , H01J35/08 , H01J35/32 , H01J2201/304 , H01J2235/087
摘要： An X-ray source includes a first support member and a second support member joined together so as to form a cavity between them and such that they are electrically insulated from each other. A cathode and an anode are located inside the cavity and opposite each other. The cathode is suitably made of diamond or diamond like material, and includes at least one pointed element.
摘要翻译： X射线源包括第一支撑构件和第二支撑构件，所述第一支撑构件和第二支撑构件连接在一起，以在它们之间形成空腔，并且使得它们彼此电绝缘。阴极和阳极位于腔内并且彼此相对。阴极适当地由金刚石或类金刚石材料制成，并且包括至少一个尖锐的元件。

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