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    • 5. 发明申请
    • Pupilary Screening Method and System
    • 学生筛选方法与系统
    • US20090174865A1
    • 2009-07-09
    • US12210185
    • 2008-09-13
    • Claudio PriviteraKamran Siminou
    • Claudio PriviteraKamran Siminou
    • A61B3/11
    • A61B3/112A61B3/0025A61B3/0083A61B3/113A61B3/14A61B3/145A61B5/4011A61B5/7203A61B2560/0425
    • A method of screening a pupil of a subject to determine whether the pupil reflex resembles a canonical pupil reflex is disclosed. The method comprises the steps of stimulating the pupil with a stimulus source. The method further includes the steps of using a pupilometer to track the pupil's constriction response over a duration of time, wherein the step of tracking the pupil constriction response begins substantially simultaneously with or immediately subsequent to time 0 and lasts for a period of time y, and using the pupilometer to collect a plurality of data points in which each data point corresponds with a diameter of the pupil at a specific time within the time duration y. The method further includes the step of generating a pupil data profile by compiling the data points and determining whether one or more conditions arc met. wherein the one or more conditions comprises the following: (a) more than two data points exist representing the same pupil diameter at three or more separate times during duration y; (b) a first phase of the pupilary reflex response exists, wherein said first phase is characterized by a period of non-constriction immediately subsequent to time 0, said first phase having a duration of less than about 100 msec or greater than about 1000 msec; (c) if two data points exist representing the same pupil diameter at two separate times y1 and y2 during duration y, then the duration of time between y1 and y2 is less than about 100 msec: or during the first phase of the pupilary reflex, the diameter of the pupil increases before it decreases. Existence of one of said conditions indicates that the pupil reflex does not resemble a canonical reflex.
    • 公开了一种筛选受试者的瞳孔以确定瞳孔反射是否类似于典型瞳孔反射的方法。 该方法包括用刺激源刺激瞳孔的步骤。 该方法还包括以下步骤:使用瞳孔仪在一段时间内跟踪瞳孔的收缩反应,其中跟踪瞳孔收缩反应的步骤基本上与时间0同时或紧随时刻0开始并持续一段时间y, 并且使用瞳孔仪来收集在该持续时间y内的特定时刻每个数据点与瞳孔的直径对应的多个数据点。 该方法还包括通过编译数据点并确定是否满足一个或多个条件来生成瞳孔数据简档的步骤。 其中所述一个或多个条件包括以下内容:(a)在持续时间y期间在三个或更多个分开的时间存在多于两个表示相同瞳孔直径的数据点; (b)存在瞳孔反射响应的第一阶段,其中所述第一阶段的特征在于在时间0之后的非收缩期,所述第一阶段具有小于约100毫秒或大于约1000毫秒的持续时间 ; (c)如果在持续时间y期间在两个分开的时间y1和y2处存在两个数据点,表示相同的瞳孔直径,则y1和y2之间的持续时间小于约100毫秒:或者在瞳孔反射的第一阶段期间, 瞳孔的直径在减小之前增加。 存在所述条件之一表明瞳孔反射不像典型的反射。
    • 7. 发明授权
    • Pupilary screening method and system
    • 学生筛选方法和系统
    • US08393734B2
    • 2013-03-12
    • US12210185
    • 2008-09-13
    • Claudio PriviteraKamran Siminou
    • Claudio PriviteraKamran Siminou
    • A61B3/08A61B3/00A61B3/10
    • A61B3/112A61B3/0025A61B3/0083A61B3/113A61B3/14A61B3/145A61B5/4011A61B5/7203A61B2560/0425
    • A method of screening a pupil of a subject to determine whether the pupil reflex resembles a canonical pupil reflex is disclosed. The method comprises the steps of stimulating the pupil with a stimulus source. The method further includes the steps of using a pupilometer to track the pupil's constriction response over a duration of time, wherein the step of tracking the pupil constriction response begins substantially simultaneously with or immediately subsequent to time 0 and lasts for a period of time y, and using the pupilometer to collect a plurality of data points in which each data point corresponds with a diameter of the pupil at a specific time within the time duration y. The method further includes the step of generating a pupil data profile by compiling the data points and determining whether one or more conditions arc met. wherein the one or more conditions comprises the following: (a) more than two data points exist representing the same pupil diameter at three or more separate times during duration y; (b) a first phase of the pupilary reflex response exists, wherein said first phase is characterized by a period of non-constriction immediately subsequent to time 0, said first phase having a duration of less than about 100 msec or greater than about 1000 msec; (c) if two data points exist representing the same pupil diameter at two separate times y1 and y2 during duration y, then the duration of time between y1 and y2 is less than about 100 msec; or during the first phase of the pupilary reflex, the diameter of the pupil increases before it decreases. Existence of one of said conditions indicates that the pupil reflex does not resemble a canonical reflex.
    • 公开了一种筛选受试者的瞳孔以确定瞳孔反射是否类似于典型瞳孔反射的方法。 该方法包括用刺激源刺激瞳孔的步骤。 该方法还包括以下步骤:使用瞳孔仪在一段时间内跟踪瞳孔的收缩反应,其中跟踪瞳孔收缩反应的步骤基本上与时间0同时或紧随时刻0开始并持续一段时间y, 并且使用瞳孔仪来收集在该持续时间y内的特定时刻每个数据点与瞳孔的直径对应的多个数据点。 该方法还包括通过编译数据点并确定是否满足一个或多个条件来生成瞳孔数据简档的步骤。 其中所述一个或多个条件包括以下内容:(a)在持续时间y期间在三个或更多个分开的时间存在多于两个表示相同瞳孔直径的数据点; (b)存在瞳孔反射响应的第一阶段,其中所述第一阶段的特征在于在时间0之后的非收缩期,所述第一阶段具有小于约100毫秒或大于约1000毫秒的持续时间 ; (c)如果在持续时间y期间在两个分开的时间y1和y2处存在两个数据点,表示相同的瞳孔直径,则y1和y2之间的持续时间小于约100毫秒; 或在瞳孔反射的第一阶段期间,瞳孔的直径在减小之前增加。 存在所述条件之一表明瞳孔反射不像典型的反射。