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1. 发明申请

US20080045965A1 Apparatus and Methods for Biopsy and Aspiration of Bone Marrow 有权
标题翻译：骨髓活检和吸入的装置和方法
公开(公告)号：US20080045965A1
公开(公告)日：2008-02-21
申请号：US11853678
申请日：2007-09-11
申请人： Larry Miller , David Bolleter , Robert Titkemeyer , Christopher Kilcoin , Matthew Harmon , Bradford Craig
发明人： Larry Miller , David Bolleter , Robert Titkemeyer , Christopher Kilcoin , Matthew Harmon , Bradford Craig
IPC分类号： A61B17/16
CPC分类号： A61B10/025 , A61B10/0283 , A61B46/00 , A61B46/10 , A61B46/23 , A61B50/30 , A61B50/33 , A61B2010/0208 , A61B2010/0258 , A61B2017/00734 , A61B2090/062 , Y10T408/94
摘要： Apparatus and methods are provided to remove biopsy specimens from a bone and/or associated bone marrow using a powered drive and an intraosseous (IO) needle set. The powered driver may rotate the IO needle set at an optimum speed to obtain a biopsy sample of bone and/or bone marrow. Apparatus and methods may also be provided for aspiration of bone marrow and/or stem cell transplant procedures. The apparatus may include a powered driver, a coupler assembly, a containment bag or sterile sleeve and various IO needles and IO needle sets with associated hubs and/or hub assemblies. Each IO needle set may include a cannula or catheter and an associated trocar stylet with respective tips operable to penetrate a bone and/or bone marrow with minimum trauma to a patient. Each hub assembly may be used to releasably dispose a respective stylet within an associated generally hollow cannula. Some coupler assemblies and/or hub assemblies may also be used with manual drivers.
摘要翻译：提供装置和方法以使用动力驱动器和骨内（IO）针组从骨骼和/或相关骨髓移除活检标本。动力驱动的驱动器可以以最佳速度旋转IO针，以获得骨和/或骨髓的活检样本。还可以提供用于抽吸骨髓和/或干细胞移植程序的装置和方法。该装置可以包括动力驱动器，联接器组件，容纳袋或无菌套筒以及具有相关联的毂和/或轮毂组件的各种IO针和IO针组。每个IO针组可以包括插管或导管和相关联的套管针管，其相应的尖端可操作以以对患者最小的创伤穿透骨和/或骨髓。每个轮毂组件可以用于将相应的管心针可释放地放置在相关联的大体上中空的套管内。一些联接器组件和/或轮毂组件也可以与手动驱动器一起使用。

2. 发明申请

US20080045860A1 Biopsy Devices and Related Methods 有权
标题翻译：活检装置及相关方法
公开(公告)号：US20080045860A1
公开(公告)日：2008-02-21
申请号：US11853685
申请日：2007-09-11
申请人： Larry Miller , David Bolleter , Robert Titkemeyer , Christopher Kilcoin , Bradford Craig
发明人： Larry Miller , David Bolleter , Robert Titkemeyer , Christopher Kilcoin , Bradford Craig
IPC分类号： A61B10/02
CPC分类号： A61B10/025 , A61B17/1637 , A61B17/32002 , A61B17/32053 , A61B46/00 , A61B46/10 , A61B46/23 , A61B50/30 , A61B50/33 , A61B2010/0258 , A61B2017/0046 , A61B2017/00477 , A61B2017/00734 , A61B2017/320064 , A61B2090/062
摘要： Apparatus and methods provided to remove biopsy specimens from bone and/or associated bone marrow. A powered driver may rotate a biopsy needle at an optimum speed to obtain the biopsy specimen. A thread or a groove may be disposed on interior portions of the biopsy needle. The thread or groove may engage a biopsy specimen and enhance removal of a bone marrow core from cancellous bone. Manufacturing procedures are provided for bonding a single helical thread with interior portions of the biopsy needle. The apparatus may also include a biopsy sample ejector and/or ejector funnel. A biopsy needle set may include a cannula and a trocar with respective tips having optimum configurations, dimensions and/or orientations relative to each other to optimize penetration of a bone and/or bone marrow with minimum patient trauma and enhanced reliability of obtaining a biopsy specimen.
摘要翻译：提供用于从骨和/或相关骨髓去除活检标本的装置和方法。动力驱动器可以以最佳速度旋转活检针以获得活检标本。螺纹或槽可以设置在活检针的内部。螺纹或凹槽可以接合活组织检查样本并增强从松质骨中去除骨髓核心。制造程序用于将单个螺旋螺纹与活检针的内部部分接合。该装置还可以包括活检样品喷射器和/或喷射器漏斗。活组织检查针组可以包括插管和套针针，针头具有相对于彼此的最佳构造，尺寸和/或取向的套管针，以便以最小的患者创伤和增强的获得活检标本的可靠性优化骨和/或骨髓的穿透。

3. 发明申请

US20070270775A1 Intraosseous Device And Methods For Accessing Bone Marrow In The Sternum And Other Target Areas 有权
标题翻译：胸骨和其他目标区域内骨髓切除装置及方法
公开(公告)号：US20070270775A1
公开(公告)日：2007-11-22
申请号：US11620927
申请日：2007-01-08
申请人： Larry J. Miller , Robert Titkemeyer , David Bolleter , Ruben Trevino , Matthew Harmon , Christopher Kilcoin
发明人： Larry J. Miller , Robert Titkemeyer , David Bolleter , Ruben Trevino , Matthew Harmon , Christopher Kilcoin
IPC分类号： A61M5/00
CPC分类号： A61B10/025 , A61B2010/0258 , A61M5/46
摘要： Apparatus and methods are provided to access bone marrow at various target areas. Such apparatus may include an intraosseous device operable to penetrate bone at a selected target area and a depth limiter operable to control depth of penetration of the intraosseous device into bone and associated bone marrow. A manual driver and a guide may be included to optimize optimum insertion of the intraosseous device at a selected insertion site on a sternum.
摘要翻译：提供了设备和方法来访问各种目标区域的骨髓。这样的装置可以包括可操作以在选定的目标区域穿透骨骼的骨内装置和可操作以控制骨内装置进入骨骼和相关骨髓的深度的深度限制器。可以包括手动驱动器和引导件以优化在胸骨上所选择的插入位置处的骨内装置的最佳插入。

4. 发明申请

US20080045857A1 Bone Marrow Aspiration Devices and Related Methods 有权
标题翻译：骨髓抽吸装置及相关方法
公开(公告)号：US20080045857A1
公开(公告)日：2008-02-21
申请号：US11853691
申请日：2007-09-11
申请人： Larry Miller , David Bolleter , Robert Titkemeyer , Christopher Kilcoin
发明人： Larry Miller , David Bolleter , Robert Titkemeyer , Christopher Kilcoin
IPC分类号： A61B10/02
CPC分类号： A61B10/025 , A61B17/32002 , A61B17/32053 , A61B46/00 , A61B46/10 , A61B46/23 , A61B50/30 , A61B50/33 , A61B2010/0258 , A61B2017/00477 , A61B2017/00734 , A61B2017/320064 , A61B2090/062
摘要： Various devices and methods may be provided to aspirate bone marrow from an associated bone using a powered drive and an aspiration needle or aspiration needle set. Such aspiration devices and methods may also be used in association with stem cell transplant procedures. The aspiration devices may include a coupler assembly, a containment bag or sterile sleeve, an ejector and/or an ejector funnel. An aspiration needle set may include a cannula and trocar with respective tips having optimum configurations, dimensions and/or orientations relative to each other to optimize penetration of a bone and/or bone marrow with minimum trauma to a patient. Exterior portions of some cannulas may include markings to indicate depth of penetration into associated bone marrow. Some cannulas may include one or more side ports for use during aspiration of bone marrow.
摘要翻译：可以提供各种装置和方法以使用动力驱动器和抽吸针或抽吸针组从相关骨吸出骨髓。这种抽吸装置和方法也可以与干细胞移植程序结合使用。抽吸装置可以包括联接器组件，容纳袋或无菌套管，喷射器和/或喷射器漏斗。抽吸针组可以包括插管和套管针，其具有相对于彼此具有最佳构造，尺寸和/或取向的相应尖端，以优化对患者的最小创伤的骨和/或骨髓的穿透。一些插管的外部部分可以包括指示穿透相关骨髓的深度的标记。一些插管可以包括用于在骨髓吸入期间使用的一个或多个侧端口。

5. 发明申请

US20080045861A1 Medical Procedures Trays And Related Methods 有权
标题翻译：医疗过程托盘及相关方法
公开(公告)号：US20080045861A1
公开(公告)日：2008-02-21
申请号：US11853701
申请日：2007-09-11
申请人： Larry Miller , David Bolleter , Robert Titkemeyer , Matthew Harmon
发明人： Larry Miller , David Bolleter , Robert Titkemeyer , Matthew Harmon
IPC分类号： A61B10/00
CPC分类号： A61B10/025 , A61B46/00 , A61B46/10 , A61B46/23 , A61B50/30 , A61B50/33 , A61B90/40 , A61B2010/0258 , A61B2017/0046 , A61B2017/00734 , A61B2090/062 , Y10T29/49826
摘要： Medical procedure trays and related methods are provided to accommodate joining a first non-sterile medical device with a second sterile medical device and maintaining required sterilization of the second sterile medical device to perform an associated medical procedure. One example of such medical procedures includes biopsy of a bone and/or associated bone marrow using a non-sterile powered drive and a sterile biopsy needle or biopsy needle set. Medical procedure trays and related methods may also be provided for use during aspiration of bone marrow and/or stem cell transplant procedures. Each medical procedure tray may include a containment bag or sterile sleeve. A coupler assembly, one or more sharps protectors, a biopsy sample ejector and/or associated ejector funnel may also be included. Some medical procedure trays may allow engaging a non-sterile powered driver with one end of a coupler assembly and sealing the non-sterile powered driver in a sterile sleeve or containment bag without compromising sterility of other components in the medical procedure tray.
摘要翻译：提供医疗装置托盘和相关方法以适应将第一非无菌医疗装置与第二无菌医疗装置接合并维持第二无菌医疗装置的必要的灭菌以执行相关联的医疗程序。这种医疗程序的一个例子包括使用非无菌驱动的驱动器和无菌活检针或活检针组对骨骼和/或相关骨髓的活组织检查。也可以提供医疗过程托盘和相关方法用于在骨髓和/或干细胞移植程序的抽吸期间使用。每个医疗处理托盘可以包括容纳袋或无菌套管。还可以包括耦合器组件，一个或多个锐利保护器，活检样品喷射器和/或相关联的喷射器漏斗。一些医疗步骤托盘可以允许将非无菌驱动的驱动器与联接器组件的一端接合并且将无菌驱动的驱动器密封在无菌套管或容纳袋中，而不会影响医疗过程托盘中的其它部件的无菌性。

6. 发明申请

US20070084742A1 Vascular Access Kits and Methods 有权
标题翻译：血管通路试剂盒和方法
公开(公告)号：US20070084742A1
公开(公告)日：2007-04-19
申请号：US11380340
申请日：2006-04-26
申请人： Larry Miller , David Bolleter , Robert Titkemeyer , Charles Schwimmer
发明人： Larry Miller , David Bolleter , Robert Titkemeyer , Charles Schwimmer
IPC分类号： A61B19/02
CPC分类号： A61B17/3472 , A61B50/20 , A61B50/31 , A61B2017/3492 , A61M5/158 , A61M2005/1581 , A61M2005/1585 , A61M2210/02
摘要： Kits carrying various components and devices are provided for use in obtaining access to a patient's vascular system. Various methods and procedures may be used to treat both emergency and more routine conditions using the contents of such kits. For example, such kits may contain various types of intraosseous (IO) devices including, but not limited to, drivers, penetrator assemblies, IO needles and other related components. Intravenous (IV) devices such as syringes, needles, IV bags, tubing and other related components for use in obtaining access to portions of a patient's vascular system may be included. Various types of connectors for communicating fluids with and/or monitoring a patient's vascular system may be provided. Such kits may contain medications, drugs and fluids used to treat a wide variety of both acute and chronic diseases and conditions.
摘要翻译：提供携带各种组件和装置的套件用于获得对患者血管系统的访问。可以使用各种方法和程序来使用这种试剂盒的内容来治疗紧急和更常规的病症。例如，这样的套件可以包含各种类型的骨内（IO）装置，包括但不限于驱动器，穿透器组件，IO针和其它相关部件。可以包括静脉内（IV）装置，例如注射器，针，IV袋，管和用于获得对患者血管系统的部分的通路的其它相关组件。可以提供用于与患者血管系统进行通信和/或监视患者血管系统的各种类型的连接器。这些试剂盒可能含有用于治疗各种急性和慢性疾病和病症的药物，药物和液体。

7. 发明申请

US20050261693A1 Apparatus and method to inject fluids into bone marrow and other target sites 有权
标题翻译：将流体注入骨髓和其他靶位置的装置和方法
公开(公告)号：US20050261693A1
公开(公告)日：2005-11-24
申请号：US11190331
申请日：2005-07-27
申请人： Larry Miller , David Bolleter , Charles Schwimmer , Robert Wilk
发明人： Larry Miller , David Bolleter , Charles Schwimmer , Robert Wilk
IPC分类号： A61B17/00 , A61B17/32 , A61B17/34 , A61B19/00 , A61M5/31 , A61M5/315 , A61M5/34
CPC分类号： A61M5/1454 , A61B17/32002 , A61B17/32053 , A61B17/3403 , A61B17/3472 , A61B17/3476 , A61B90/11 , A61B2017/3413 , A61B2090/034 , A61M5/158 , A61M5/2033 , A61M5/24 , A61M5/31511 , A61M5/3291 , A61M5/34 , A61M2005/1581 , A61M2005/1585 , A61M2005/3103 , A61M2005/3289 , A61M2210/02
摘要： Apparatus for delivering a quantity of fluid to bone marrow of a bone or providing access to remove fluids from a target site is provided. The apparatus may include a driver, a plunger operating and cartridge assembly mechanism, a cartridge assembly having a fluid reservoir and a bone penetrating needle.
摘要翻译：提供了用于将一定量的流体输送到骨的骨髓或提供从目标部位去除流体的通道的装置。该装置可以包括驱动器，柱塞操作和盒组件机构，具有流体储存器和骨穿透针的盒组件。

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