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1. 发明授权

US5212879A Method for manufacturing a disposable-retractable finger stick device 失效
标题翻译：一次性伸缩指棒装置的制造方法
公开(公告)号：US5212879A
公开(公告)日：1993-05-25
申请号：US868630
申请日：1992-04-14
申请人： Ladislau Biro , Robert F. Cusack , Michael D. Mintz
发明人： Ladislau Biro , Robert F. Cusack , Michael D. Mintz
IPC分类号： A61B5/15 , A61B17/32
CPC分类号： A61B17/32093 , A61B5/150022 , A61B5/150297 , A61B5/150442 , A61B5/15113 , A61B5/15128 , A61B5/15142 , A61B5/15144 , A61B5/15029 , Y10S29/029 , Y10T29/49845 , Y10T29/49861 , Y10T29/49876
摘要： A finger stick device for making a skin incision includes a blade pivot arm having a first end pivotally coupled to a housing and a second end having an upper sloped surface and a lower surface. A blade is affixed to the second end such that its cutting edge extends away from the lower surface. A resilient bias member when actuated traverses the upper surface and depresses the second end of the blade pivot arm, such that the blade exits the housing and incises the skin. The incising operation is complete upon the bias member traversing the sloped upper surface of the blade pivot arm. Also disclosed herein is a method for manufacturing the finger stick device, in which the bias member and blade pivot arm are molded as a monolithic unit. A blade is attached to the blade pivot arm, and the blade and monolithic unit are inserted into the housing. Further disclosed is an embodiment in which the housing is formed of two uniformly shaped halves, which when joined, provide an internal space for the monolithic unit. In this manner, the two halves are joined with the monolithic unit aligned therebetween so that the housing appears as an integral unit.
摘要翻译：用于制造皮肤切口的指棒装置包括刀片枢转臂，刀片枢转臂具有枢转地联接到壳体的第一端和具有上倾斜表面和下表面的第二端。叶片固定到第二端，使得其切割边缘远离下表面延伸。当致动的弹性偏压构件穿过上表面并压下刀片枢转臂的第二端，使得刀片离开外壳并切割皮肤。在偏置构件穿过叶片枢转臂的倾斜上表面时，切割操作完成。本文还公开了一种用于制造指棒装置的方法，其中偏压构件和叶片枢转臂被模制为单片单元。叶片连接到叶片枢转臂，并且叶片和整体单元插入壳体中。进一步公开的是其中壳体由两个均匀成形的半部形成的实施例，当连接时，壳体提供用于整体式单元的内部空间。以这种方式，两个半体与整体单元连接在一起，使得外壳看起来是一体的单元。

2. 发明授权

US5133730A Disposable-retractable finger stick device 失效
标题翻译：一次性伸缩手指棒装置
公开(公告)号：US5133730A
公开(公告)日：1992-07-28
申请号：US700592
申请日：1991-05-15
申请人： Ladislau Biro , Robert F. Cusack , Michael D. Mintz
发明人： Ladislau Biro , Robert F. Cusack , Michael D. Mintz
IPC分类号： A61B5/15 , A61B17/32
CPC分类号： A61B17/32093 , A61B5/150022 , A61B5/150297 , A61B5/150442 , A61B5/15113 , A61B5/15128 , A61B5/15142 , A61B5/15144 , A61B5/15029 , Y10S29/029 , Y10T29/49845 , Y10T29/49861 , Y10T29/49876
摘要： A finger stick device for making a skin incision includes a blade pivot arm having a first end pivotally coupled to a housing and a second end having an upper sloped surface and a lower surface. A blade is affixed to the second end such that its cutting edge extends away from the lower surface. A resilient bias member when actuated traverses the upper surface and depresses the second end of the blade pivot arm, such that the blade exits the housing and incises the skin. The incising operation is complete upon the bias member traversing the sloped upper surface of the blade pivot arm. Also disclosed herein is a method for manufacturing the finger stick device, in which the bias member and blade pivot arm are molded as a monolithic unit. A blade is attached to the blade pivot arm, and the blade and monolithic unit are inserted into the housing. Further disclosed is an embodiment in which the housing is formed of two uniformly shaped halves, which when joined, provide an internal space for the monolithic unit. In this manner, the two halves are joined with the monolithic unit aligned therebetween so that the housing appears as an integral unit.
摘要翻译：用于制造皮肤切口的指棒装置包括刀片枢转臂，刀片枢转臂具有枢转地联接到壳体的第一端和具有上倾斜表面和下表面的第二端。叶片固定到第二端，使得其切割边缘远离下表面延伸。当致动的弹性偏压构件穿过上表面并压下刀片枢转臂的第二端，使得刀片离开外壳并切割皮肤。在偏置构件穿过叶片枢转臂的倾斜上表面时，切割操作完成。本文还公开了一种用于制造指棒装置的方法，其中偏压构件和叶片枢转臂被模制为单片单元。叶片连接到叶片枢转臂，并且叶片和整体单元插入壳体中。进一步公开的是其中壳体由两个均匀成形的半部形成的实施例，当连接时，壳体提供用于整体式单元的内部空间。以这种方式，两个半体与整体单元连接在一起，使得外壳看起来是一体的单元。

3. 发明授权

US5380665A Fluid sample collection and delivery system and methods particularly adapted for body fluid sampling 失效
标题翻译：流体样品收集和输送系统和方法特别适用于体液取样
公开(公告)号：US5380665A
公开(公告)日：1995-01-10
申请号：US009417
申请日：1993-01-27
申请人： Robert F. Cusack , Michael D. Mintz
发明人： Robert F. Cusack , Michael D. Mintz
IPC分类号： G01N35/08
CPC分类号： G01N35/08 , Y10T436/118339
摘要： There is disclosed apparatus for transporting a sample of body fluid such as blood from a first location to a remote test site location. The apparatus operates in conjunction with a fluid manifold module which has a first sample input port, a second washing fluid input port and a third input port for receiving air. There are tubes coupled to said first, second and third input ports which are coupled together and coupled to a sample output line which extends from the first location to the remote location. The manifold contains check valves with one valve for blood and one valve for washing fluid and a diaphragm pump for air. There are logic controls which selectively operate the valves and pump to allow the sample line to receive a sample separated by air barriers from washing fluid solution. In this manner, a predetermined volume of sample is transported from the first location to the remote test site location. At the test site location, the presence of sample is detected by detection sensors and the sample is directed to a test site. The remainder of materials such as the washing fluid and air are discharged at the remote location. The system includes flexible tubing and the fluids as present are pumped from the first location to the remote location by ways of a peristaltic pump or other pump in direct contact with the tubing.
摘要翻译：公开了一种用于将诸如血液的体液样本从第一位置运送到远程测试位置的装置。该装置与具有第一样品输入端口，第二洗涤流体输入端口和用于接收空气的第三输入端口的流体歧管模块一起操作。存在耦合到所述第一，第二和第三输入端口的管，其耦合在一起并耦合到从第一位置延伸到远程位置的采样输出线。歧管包含止回阀，带有一个用于血液的阀和一个用于洗涤液的阀和一个用于空气的隔膜泵。有逻辑控制器可以选择性地操作阀门和泵，以允许样品管线从洗涤液体溶液接收由空气屏障分离的样品。以这种方式，将预定体积的样品从第一位置运送到远程测试位置。在测试位置，检测传感器检测样品的存在，样品被引导到测试位置。剩余的诸如洗涤液和空气的材料在远程位置排出。该系统包括柔性管道，并且现有的流体通过与管道直接接触的蠕动泵或其它泵的方式从第一位置泵送到远程位置。

4. 发明授权

US5134079A Fluid sample collection and delivery system and methods particularly adapted for body fluid sampling 失效
标题翻译：流体样品采集和输送系统和特别适用于体液采样的方法
公开(公告)号：US5134079A
公开(公告)日：1992-07-28
申请号：US329340
申请日：1989-03-27
申请人： Robert F. Cusack , Michael D. Mintz
发明人： Robert F. Cusack , Michael D. Mintz
IPC分类号： G01N35/08
CPC分类号： G01N35/08 , Y10T436/117497 , Y10T436/118339
摘要： There is disclosed apparatus for transporting a sample of body fluid such as blood from a first location to a remote test site location. The apparatus operates in conjunction with a fluid manifold module which has a first sample input port, a second washing fluid input port and a third input port for receiving air. There are tubing means coupled to said first, second and third input ports which are coupled together and coupled to a sample output line which extends from the first location to the remote location. The manifold means contains check valves with one valve for blood and one valve for washing fluid and a diaphragm pump for air. There are logic means which selectively operate the valves and pump to allow the sample line to receive a sample separated by air barriers from washing fluid solution. In this manner, a predetermined volume of sample is transported from the first location to the remote test site location. At the test site location, the presence of sample is detected by detection means and the sample is directed to a test site. The remainder of materials such as the washing fluid and air are discharged at the remote location. The system includes flexible tubing and the fluids as present are pumped from the first locaiton to the remote location by means of a peristaltic pump or other pump in direct contact with the tubing.

5. 发明授权

US5055099A Apparatus and method for utilizing autotransfusion systems and related equipment 失效
标题翻译：使用自动补偿系统和相关设备的装置和方法
公开(公告)号：US5055099A
公开(公告)日：1991-10-08
申请号：US340773
申请日：1989-04-20
申请人： Michael D. Mintz
发明人： Michael D. Mintz
IPC分类号： A61M1/02
CPC分类号： A61M1/02
摘要： There is disclosed an autotransfusion system which essentially is contained in a unitary housing section which enables a practitioner to utilize the system in a rapid and efficient manner. The housing section has integrally associated therewith a blood reservoir, which is a major component of an autotransfusion system. The housing has secured thereto a set of instructions which are adapted to be mounted on the arm of an IV pole and which, when positioned on the arm of the IV pole, specifies vertical distances necessary to perform autotransfusion during a blood collection or blood distribution mode. The housing section, as containing the reservoir, with the package and instruction component, is used as a yardstick to establish specified distances in order to control pressure as afforded by gravity. The entire unit lends itself to the rapid installation of an autotransfusion system while providing visual instructions which are integrally associated therewith to provide users with operational guidance that is thereby readily available during an operative procedure. The housing further permits pre-assembly and sterilization of the various components of an autotransfusion system.

6. 发明授权

US5154082A Microprocessor-controlled apparatus and method for detecting the coagulation of blood 失效
标题翻译：用于检测血液凝固的微处理器控制装置和方法
公开(公告)号：US5154082A
公开(公告)日：1992-10-13
申请号：US703288
申请日：1991-05-20
申请人： Michael D. Mintz
发明人： Michael D. Mintz
IPC分类号： G01N33/49
CPC分类号： G01N33/4905
摘要： Apparatus and method for detecting the coagulation of a sample of blood includes a ferromagnetic member, which is immersed in the blood sample and which is magnetically coupled to a reed switch, and an adjustable source of magnetic flux lines, which is also magnetically coupled to the reed switch. As the blood sample coagulates, the ferromagnetic member is displaced from the reed switch and, as a result, the magnetic field coupled to reed switch is reduced. When the ferromagnetic member reaches a predetermined displacement, the reed switch is open, which indicates that blood has coagulated. A microprocessor calibrates the reed switch by adjusting the density of the magnetic flux lines from the adjustable source such that the reed switch is open when the ferromagnetic member reaches the predetermined distance displacement.
摘要翻译：用于检测血液样本凝固的装置和方法包括铁磁部件，其浸入血液样品中并与磁簧耦合到舌簧开关，以及可调节的磁通量源，其也磁耦合到簧片开关当血液样本凝结时，铁磁构件从簧片开关移位，结果减少了与簧片开关耦合的磁场。当铁磁部件达到预定的位移时，簧片开关打开，这表明血液已凝结。微处理器通过调节来自可调节源的磁通线的密度来校准舌簧开关，使得当铁磁部件达到预定距离位移时，簧片开关打开。

7. 发明授权

US4867738A Apparatus and methods for utilizing autotransfusion systems and related equipment 失效
标题翻译：利用自体输血系统及相关设备的装置和方法
公开(公告)号：US4867738A
公开(公告)日：1989-09-19
申请号：US93050
申请日：1987-09-14
申请人： Michael D. Mintz
发明人： Michael D. Mintz
IPC分类号： A61M1/02
CPC分类号： A61M1/02
摘要： There is disclosed an autotransfusion system which essentially is contained in a unitary housing section which enables a practitioner to utilize the system in a rapid and efficient manner. The housing section has integrally associated therewith a blood reservoir, which is a major component of an autotransfusion system. The housing has secured thereto a set of instructions which are adapted to be mounted on the arm of an IV pole and which, when positioned on the arm of the IV pole, specifies vertical distances necessary to perform autotransfusion during a blood collection or blood distribution mode. The housing section, as containing the reservoir, with the package and instruction component, is used as a yardstick to establish specified distances in order to control pressure as afforded by gravity. The entire unit lends itself to the rapid installation of an autotransfusion system while providing visual instructions which are integrally associated therewith to provide users with operational guidance that is thereby readily available during an operative procedure. The housing further permits pre-assembly and sterilization of the various components of an autotransfusion system.
摘要翻译：公开了一种自动输血系统，其基本上包含在单一的住房部分中，其使得从业者能够以快速且有效的方式利用该系统。壳体部分与其一体地连接有作为自动输血系统的主要部件的血液储存器。外壳已经固定了一组指令，其适于安装在IV杆的臂上，并且当定位在IV杆的臂上时指定在采血或血液分配模式期间执行自体输血所需的垂直距离。使用包含储存器的壳体部分与包装和指导部件作为衡量指定距离的尺度，以便控制由重力提供的压力。整个单元适用于快速安装自动输血系统，同时提供与其整体相关联的视觉指令，以向用户提供由此在手术过程中容易获得的操作指导。外壳还允许自动输血系统的各种部件的预组装和灭菌。

8. 发明授权

US4671939A Apparatus for analyzing the influence of additive reagents upon the coagulation of blood and related methods 失效
标题翻译：用于分析添加剂对凝血凝血的影响的装置及相关方法
公开(公告)号：US4671939A
公开(公告)日：1987-06-09
申请号：US751325
申请日：1985-07-02
申请人： Michael D. Mintz
发明人： Michael D. Mintz
IPC分类号： G01N33/86
CPC分类号： G01N33/86
摘要： There is shown a cartridge assembly which is used to analyze the coagulation of blood when subjected to an additive reagent. A base plate is divided into two sections as a right and left section by means of a longitudinal groove. Located on the right side of the groove is a plurality of first cylindrical chambers. Located on the left side of the groove is a second plurality of cylindrical chambers. The chambers on the right side of the groove have a top depression with sloping sidewalls which are adapted to receive extending tapered flanges associated with the chambers on the left side of the groove. In this manner upon folding or pivoting the cartridge about the groove, the chambers on the left and right side coact with one another. In operation the chambers on the left side of the groove receive a blood sample while the chambers on the right side of the groove receive a suitable reagent. When the apparatus is closed, the chambers communicate one with the other and a support shelf is formed between the chambers. The assembly can be agitated in order to provide a coagulation test.
摘要翻译：示出了当进行添加剂试剂时用于分析血液凝固的盒组件。基板通过纵向槽分为左右两部分。位于凹槽右侧的是多个第一圆柱形腔室。位于槽的左侧的是第二多个圆柱形腔室。凹槽右侧的腔室具有倾斜侧壁的顶部凹陷，其适于接纳与凹槽左侧的腔室相关联的延伸锥形凸缘。以这种方式，当围绕凹槽折叠或枢转盒时，左侧和右侧的腔室彼此共同作用。在操作中，槽的左侧的腔室接收血液样本，而槽的右侧的腔室接收合适的试剂。当设备关闭时，室与另一个连通，并且在室之间形成支撑架。可以搅拌组件以提供凝结试验。

9. 发明授权

US4551308A Apparatus for analyzing the influence of additive reagents upon the coagulation of blood and related methods 失效
标题翻译：用于分析添加剂对凝血凝血的影响的装置及相关方法
公开(公告)号：US4551308A
公开(公告)日：1985-11-05
申请号：US549070
申请日：1983-12-23
申请人： Michael D. Mintz
发明人： Michael D. Mintz
IPC分类号： G01N33/86 , G01N21/03 , G01N21/75
CPC分类号： G01N33/86
摘要： A sample of blood is divided into a plurality of isolated test chambers. The blood is mixed with additive reagent having previously been measured into each test chamber. A clot detector and analyzer system determines the time required for the blood-reagent mixture in each chamber to form a clot. In a first mode of analyzer system operation there is recorded the time required for a selected number of clots to be detected. A second mode of operation identifies those chambers in which clots have been detected within a specified time interval.
摘要翻译：将血液样本分成多个分离的测试室。将血液与先前已经测量到每个测试室中的添加剂混合。凝块检测器和分析仪系统确定每个室中的血液试剂混合物形成凝块所需的时间。在分析仪系统操作的第一模式中，记录了所选择的凝块数量被检测所需的时间。第二种操作模式识别在指定的时间间隔内检测到血块的那些腔室。

10. 发明授权

US4443408A Apparatus for analyzing the influence of additive reagents upon the coagulation of blood 失效
标题翻译：用于分析添加剂对血液凝结的影响的装置
公开(公告)号：US4443408A
公开(公告)日：1984-04-17
申请号：US281661
申请日：1981-07-09
申请人： Michael D. Mintz
发明人： Michael D. Mintz
IPC分类号： G01N33/86
CPC分类号： G01N33/86
摘要： A sample of blood is divided into a plurality of isolated test chambers. The blood is mixed with additive reagent having previously been measured into each test chamber. A clot detector and analyzer system determines the time required for the blood-reagent mixture in each chamber to form a clot. In a first mode of analyzer system operation there is recorded the time required for a selected number of clots to be detected. A second mode of operation identifies those chambers in which clots have been detected within a specified time interval.
摘要翻译：将血液样本分成多个分离的测试室。将血液与先前已经测量到每个测试室中的添加剂混合。凝块检测器和分析仪系统确定每个室中的血液试剂混合物形成凝块所需的时间。在分析仪系统操作的第一模式中，记录了所选择的凝块数量被检测所需的时间。第二种操作模式识别在指定的时间间隔内检测到血块的那些腔室。

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