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1. 发明申请

US20110212514A1 METHOD AND APPARATUS FOR DISRUPTING CELLS AND AMPLIFYING NUCLEIC ACIDS USING GOLD NANORODS 有权
标题翻译：破坏细胞的方法和装置，使用金纳多糖放大核酸
公开(公告)号：US20110212514A1
公开(公告)日：2011-09-01
申请号：US13107677
申请日：2011-05-13
申请人： Kwang Ho CHEONG , Dong-kee YI , Jeong-gun LEE , Jong-myeon PARK
发明人： Kwang Ho CHEONG , Dong-kee YI , Jeong-gun LEE , Jong-myeon PARK
IPC分类号： C12M1/00 , C12M1/02 , C12M1/42
CPC分类号： C12N1/066 , C12M47/06 , C12N13/00 , C12P19/34
摘要： Provided is a method of disrupting cells comprising adding gold nanorods to a solution containing cells and irradiating the gold nanorods with a laser to disrupt the cells. A method and an apparatus for continuously disrupting cells and amplifying nucleic acids in a single microchamber are also provided, wherein the method comprises introducing a solution containing cells and gold nanorods into a microchamber, irradiating a laser onto the gold nanorods to disrupt the cells, and amplifying a nucleic acid from the disrupted cells in the microchamber.
摘要翻译：提供一种破坏细胞的方法，包括向含有细胞的溶液中加入金纳米棒并用激光照射金纳米棒以破坏细胞。还提供了用于在单个微室中连续破坏细胞和扩增核酸的方法和装置，其中所述方法包括将含有细胞和金纳米棒的溶液引入微室中，将激光照射到金纳米棒上以破坏细胞，以及在微室中从破碎的细胞中扩增核酸。

2. 发明申请

US20080171366A1 METHOD AND APPARATUS FOR DISRUPTING CELLS AND AMPLIFYING NUCLEIC ACIDS USING GOLD NANORODS 有权
标题翻译：破坏细胞的方法和装置，使用金纳多糖放大核酸
公开(公告)号：US20080171366A1
公开(公告)日：2008-07-17
申请号：US11838550
申请日：2007-08-14
申请人： Kwang Ho CHEONG , Dong-kee YI , Jeong-gun LEE , Jong-myeon PARK
发明人： Kwang Ho CHEONG , Dong-kee YI , Jeong-gun LEE , Jong-myeon PARK
IPC分类号： C12N13/00 , C12P19/34 , C12M1/00
CPC分类号： C12N1/066 , C12M47/06 , C12N13/00 , C12P19/34
摘要： Provided is a method of disrupting cells comprising adding gold nanorods to a solution containing cells and irradiating the gold nanorods with a laser to disrupt the cells. A method and an apparatus for continuously disrupting cells and amplifying nucleic acids in a single microchamber are also provided, wherein the method comprises introducing a solution containing cells and gold nanorods into a microchamber, irradiating a laser onto the gold nanorods to disrupt the cells, and amplifying a nucleic acid from the disrupted cells in the microchamber.
摘要翻译：提供一种破坏细胞的方法，包括向含有细胞的溶液中加入金纳米棒并用激光照射金纳米棒以破坏细胞。还提供了用于在单个微室中连续破坏细胞和扩增核酸的方法和装置，其中所述方法包括将含有细胞和金纳米棒的溶液引入微室中，将激光照射到金纳米棒上以破坏细胞，以及在微室中从破碎的细胞中扩增核酸。

3. 发明申请

US20110104176A1 ANTIBODY SPECIFICALLY BINDING TO C-MET AND USE THEREOF 有权
标题翻译：抗体特异性地与C-MET结合并使用
公开(公告)号：US20110104176A1
公开(公告)日：2011-05-05
申请号：US12907604
申请日：2010-10-19
申请人： Kwang Ho CHEONG , Sang-hyun PAEK
发明人： Kwang Ho CHEONG , Sang-hyun PAEK
IPC分类号： A61K39/395 , C12N5/12 , C07K16/28 , C07H21/04 , C12N15/63 , C12N5/00 , A61P35/00 , A61P25/28 , A61P17/06 , A61P19/02 , A61P9/10 , C12P21/04 , G01N33/53
CPC分类号： C07K16/2863 , A61K2039/505 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/92
摘要： Antibodies specifically binding to c-Met protein, hybridoma cell lines, and compositions comprising the antibodies are disclosed herein. Methods of making and using the antibodies and compositions are also disclosed.
摘要翻译：本文公开了与c-Met蛋白，杂交瘤细胞系以及包含抗体的组合特异性结合的抗体。还公开了制备和使用抗体和组合物的方法。

4. 发明申请

US20130089556A1 ANTI C-MET HUMANIZED ANTIBODY AND USES THEREOF 有权
标题翻译：抗C-MET人类抗体及其用途
公开(公告)号：US20130089556A1
公开(公告)日：2013-04-11
申请号：US13589789
申请日：2012-08-20
申请人： Kwang Ho CHEONG , Seunghyun LEE , Geun Woong KIM , Kyung-Ah KIM , Young Mi OH , Saet Byoul LEE , Soo-yeon JUNG , Yunju JEONG , Young Kue HAN
发明人： Kwang Ho CHEONG , Seunghyun LEE , Geun Woong KIM , Kyung-Ah KIM , Young Mi OH , Saet Byoul LEE , Soo-yeon JUNG , Yunju JEONG , Young Kue HAN
IPC分类号： A61K39/395 , A61P35/00 , A61P35/02 , C07K16/32
CPC分类号： A61K39/39558 , A61K2039/505 , C07K16/2863 , C07K2317/24 , C07K2317/53 , C07K2317/565 , C07K2317/73 , C07K2317/75 , C07K2317/92
摘要： An anti c-Met antibody, a composition comprising the antibody, and a method for preventing or treating cancer by administering the composition is provided.
摘要翻译：提供了抗c-Met抗体，包含该抗体的组合物，以及通过施用该组合物预防或治疗癌症的方法。

5. 发明申请

US20070249041A1 CELL CO-CULTURE APPARATUS FOR RESEARCHING CELL INTERACTION AND METHOD THEREOF 有权
标题翻译：用于研究细胞相互作用的细胞共培养装置及其方法
公开(公告)号：US20070249041A1
公开(公告)日：2007-10-25
申请号：US11626523
申请日：2007-01-24
申请人： Kwang Ho CHEONG , Chin-sung PARK
发明人： Kwang Ho CHEONG , Chin-sung PARK
IPC分类号： C12M3/00
CPC分类号： C12M23/12 , C12M23/44 , C12M35/08 , C12M47/04
摘要： A cell co-culture apparatus and a method of co-culturing and isolating cells using the cell co-culture apparatus to research interactions between cells by direct contact between the cells are provided. The cell co-culture apparatus includes a first substrate including a substrate portion and a plurality of projections provided on a surface of the substrate portion, each of the projections having a top surface for culturing cells, a second substrate including a same number of first channels as a number of the projections such that the channels fit with the projections and substrate surfaces formed between the first channels, and a third substrate including a plurality of second channels corresponding with the top surfaces and a plurality of third channels corresponding with the substrate surfaces.
摘要翻译：提供了一种细胞共培养装置和使用细胞共培养装置共培养和分离细胞的方法，以通过细胞之间的直接接触来研究细胞之间的相互作用。细胞共培养装置包括：第一基板，包括基板部分和设置在基板部分的表面上的多个突起，每个突起具有用于培养单元的顶表面;第二基板，包括相同数量的第一通道作为多个突起，使得通道与形成在第一通道之间的突起和基板表面配合，以及包括与顶表面相对应的多个第二通道的第三基板和对应于基板表面的多个第三通道。

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