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1. 发明申请

US20070191489A1 Inorganic acid salts of sibutramine 失效
标题翻译：西布曲明的无机酸盐
公开(公告)号：US20070191489A1
公开(公告)日：2007-08-16
申请号：US10580136
申请日：2006-01-06
申请人： Dong Lim , Eun Yang , Jae Ko , Kwang Choi , Yong Youn , Hea Suh , Chang Kim
发明人： Dong Lim , Eun Yang , Jae Ko , Kwang Choi , Yong Youn , Hea Suh , Chang Kim
IPC分类号： A61K31/137
CPC分类号： C07C211/63 , C07C2601/04
摘要： Disclosed are novel inorganic acid salts of sibutramine, which have good physicochemical properties, and crystalline forms thereof. Also disclosed are pharmaceutical compositions comprising the compounds as effective ingredients, methods of preparing the compounds, and the use of the compounds.
摘要翻译：公开了具有良好物理化学性质的西布曲明的新型无机酸盐及其结晶形式。还公开了包含化合物作为有效成分的药物组合物，制备化合物的方法和化合物的用途。

2. 发明申请

US20070191482A1 Dicarboxylic acid salt of sibutramine 失效
标题翻译：西布曲明的二羧酸盐
公开(公告)号：US20070191482A1
公开(公告)日：2007-08-16
申请号：US10580132
申请日：2006-01-06
申请人： Kwang Choi , Yong Youn , Hea Suh , Dong Lim , Eun Yang , Jae Ko , Chang Kim
发明人： Kwang Choi , Yong Youn , Hea Suh , Dong Lim , Eun Yang , Jae Ko , Chang Kim
IPC分类号： A61K31/205 , C07C211/20
CPC分类号： C07C211/29 , C07C2601/04
摘要： Disclosed is a novel dicarboxylic acid salt of sibutramine, which has good physicochemical properties. Also disclosed are a method of preparing the compound and a pharmaceutical composition comprising the compound.
摘要翻译：公开了西布曲明的新型二羧酸盐，具有良好的物理化学性质。还公开了制备该化合物的方法和包含该化合物的药物组合物。

3. 发明申请

US20070122480A1 Sustained release formulations 审中-公开
标题翻译：缓释制剂
公开(公告)号：US20070122480A1
公开(公告)日：2007-05-31
申请号：US10574337
申请日：2004-09-25
申请人： Seong Cho , Jeong Ku , Dong Lim , Jun Cheon , Tae An , Jae Ko , Yong Youn , Choong Park , Hea Suh , Eun Yang , Eun Jeon , Chang Kim
发明人： Seong Cho , Jeong Ku , Dong Lim , Jun Cheon , Tae An , Jae Ko , Yong Youn , Choong Park , Hea Suh , Eun Yang , Eun Jeon , Chang Kim
IPC分类号： A61K9/24
CPC分类号： A61K9/209
摘要： Provided is a sustained-release formulation: (a) a sustained-release core including an active ingredient and a polymer having erosion and swelling property in mammalian intestinal secretions, (b) an enteric film coating layer coated on the sustained-release core, and (c) an active ingredient-containing film coating layer coated on the enteric film coating layer and including the active ingredient and hydrophilic polymer for film coating.
摘要翻译：提供一种缓释制剂：（a）包含活性成分的缓释核心和在哺乳动物肠分泌物中具有侵蚀和溶胀性质的聚合物，（b）涂覆在缓释核心上的肠溶薄膜包衣层，以及（c）涂覆在肠溶薄膜包衣层上的含活性成分的膜包衣层，并且包括活性成分和用于薄膜包衣的亲水性聚合物。

4. 发明申请

US20070134522A1 Method of activating vehicle fuel cell 有权
标题翻译：车辆燃料电池的启动方法
公开(公告)号：US20070134522A1
公开(公告)日：2007-06-14
申请号：US11603872
申请日：2006-11-22
申请人： Jae Ko , Hwan Shin , Young Kim , Sae Kim
发明人： Jae Ko , Hwan Shin , Young Kim , Sae Kim
IPC分类号： H01M8/04
CPC分类号： H01M8/04029 , H01M8/04126 , H01M8/04223 , H01M8/04302 , H01M2250/20 , Y02P70/56 , Y02T90/32
摘要： The method of activating a vehicle fuel cell for ensuring maximum performance, improves performance of a polymer electrolyte membrane fuel cell, reduces a hydrogen usage, and has stable performance after manufactured. The method includes: placing a fuel cell in an activation device so as to be activated; changing a humidification state of a humidifier which supplies vapor to the fuel cell and a state of a cooling water; supplying a reactant gas to the fuel cell and maintaining a no-load state; maintaining a load state while changing a flow rate of the vapor and gas supplied to the fuel cell; changing the sate of the fuel cell to the no-load state, and re-supplying the reactant gas to the fuel cell; and comparing data measured when the fuel cell operates in the no-load state and data measured when the fuel cell operates in the load state respectively with a reference value.
摘要翻译：为了确保最佳性能而激活车辆用燃料电池的方法，提高高分子电解质膜燃料电池的性能，降低氢的使用量，制造后的性能稳定。该方法包括：将燃料电池放置在激活装置中以便被激活; 改变向燃料电池供应蒸汽的加湿器的加湿状态和冷却水的状态; 向燃料电池供应反应气体并保持空载状态; 在改变供应到燃料电池的蒸汽和气体的流量的同时保持负载状态; 将燃料电池的状态改变为空载状态，并将反应气体再供给到燃料电池; 以及比较当在空载状态下燃料电池工作时测量的数据和当燃料电池在负载状态下分别以参考值工作时测量的数据。

5. 发明申请

US20050118254A1 Microemulsion preconcentrate 审中-公开
标题翻译：微乳液预浓缩
公开(公告)号：US20050118254A1
公开(公告)日：2005-06-02
申请号：US10500230
申请日：2002-12-26
申请人： Jae Choi , Eun Jeon , Jae Ko , Young Park , Myoung Baek , Su Yang , Eun Jeong
发明人： Jae Choi , Eun Jeon , Jae Ko , Young Park , Myoung Baek , Su Yang , Eun Jeong
IPC分类号： A61K47/44 , A61K20060101 , A61K9/08 , A61K9/10 , A61K9/107 , A61K9/48 , A61K38/00 , A61K47/14 , A61K38/13 , A61K31/195 , A61K31/56 , A61K31/704 , A61K31/7072
CPC分类号： A61K9/1075 , A61K9/4858
摘要： A microemulsion preconcentrate is provided, which comprises an active component, an oil, a surfactant, and a hydrophilic solvent selected from the group consisting of propylene glycol diacetate, propylene glycol monoacetate, and salts of the forgoing materials.
摘要翻译：提供了一种微乳液预浓缩物，其包含选自丙二醇二乙酸酯，丙二醇单乙酸酯和前述材料的盐的活性组分，油，表面活性剂和亲水性溶剂。

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