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    • 1. 发明授权
    • Method for early diagnosis of alzheimer'S disease using phototransistor
    • 使用光电晶体管早期诊断阿尔茨海默氏病的方法
    • US09023607B2
    • 2015-05-05
    • US13093152
    • 2011-04-25
    • Kwan-Su KimCheol-Joo ChaeJae-Min KangJeong-Dae SuhMyung-Ae ChungKi-Bong Song
    • Kwan-Su KimCheol-Joo ChaeJae-Min KangJeong-Dae SuhMyung-Ae ChungKi-Bong Song
    • C12Q1/00B82Y15/00G01N33/68
    • B82Y15/00G01N33/6896G01N2800/2821
    • A method for diagnosing Alzheimer's disease by detecting the presence of beta-amyloid in cells using a phototransistor device. Cells that potentially contain beta-amyloid are provided and labeled with a multi-protein that selectively binds to beta-amyloid if present and that includes streptavidin, biotin and polyethylene glycol connected in sequence with the streptavidin being bound to a magnetic bead and the polyethylene glycol being bound to the beta-amyloid, to provide labeled cells. A phototransistor device including a channel layer is provided and a difference in photocurrent determined corresponding to incident light measured before and after selectively fixing the labeled cells on a surface of the channel layer by applying an external magnetic field effective to attract the magnetic bead to the phototransistor device through a permanent magnet positioned below the channel. Any difference between the first and second photocurrents indicates the presence of, and optionally amount of, labeled beta-amyloid in the cells.
    • 一种通过使用光电晶体管装置检测细胞中β-淀粉样蛋白的存在来诊断阿尔茨海默病的方法。 提供可能含有β-淀粉样蛋白的细胞并用选择性结合β-淀粉样蛋白(如果存在)的多蛋白标记,并且包括与链霉抗生物素蛋白结合到磁珠上的序列连接的链霉抗生物素蛋白,生物素和聚乙二醇,并且聚乙二醇 结合β-淀粉样蛋白,以提供标记细胞。 提供了包括沟道层的光电晶体管装置,并且通过施加有效吸引磁珠到光电晶体管的外部磁场选择性地将标记的单元选择性地固定在通道层的表面之前和之后测量的入射光确定的光电流差异 设备通过位于通道下方的永磁体。 第一和第二光电流之间的任何差异表明在细胞中存在和任选量的标记的β-淀粉样蛋白。
    • 8. 发明授权
    • Method for manufacturing a superconductor-insulator-superconductor
Josephson tunnel junction
    • 制造超导体 - 绝缘体 - 超导体约瑟夫逊隧道结的方法
    • US5750474A
    • 1998-05-12
    • US708499
    • 1996-09-05
    • Gun-Yong SungJeong-Dae Suh
    • Gun-Yong SungJeong-Dae Suh
    • H01L39/22H01L39/24
    • H01L39/223H01L39/2496Y10S505/702Y10S505/728
    • A superconductor-insulator-superconductor Josephson tunnel junction, comprising: a single crystalline substrate having a perovskite crystal structure; a template layer formed of a b-axis oriented PBCO thin film on the substrate; and a trilayer structure consisting of a lower electrode, a barrier layer and an upper electrode, which serve as a superconductor, an insulator and a superconductor, respectively, the lower electrode and the upper electrode each being formed of an a-axis oriented YBCO superconducting thin film and having an oblique junction edge at an angle of 30.degree. to 70.degree., the barrier layer being formed of an insulating thin film between the two superconducting electrodes, can be operated at a low power with an exceptional speed in calculation and data processing.
    • 超导体 - 绝缘体 - 超导体约瑟夫逊隧道结,包括:具有钙钛矿晶体结构的单晶衬底; 在基板上由b轴取向的PBCO薄膜形成的模板层; 以及分别由用作超导体,绝缘体和超导体的下电极,阻挡层和上电极组成的三层结构,所述下电极和上电极各自由a轴取向的YBCO超导体 薄膜,并且在30°至70°的角度具有倾斜的接合边缘,阻挡层由两个超导电极之间的绝缘薄膜形成,可以在计算和数据处理中以非常高的速度以低功率运行 。
    • 9. 发明授权
    • Superconductor-insulator-superconductor Josephson tunnel junction and
method therefor
    • 超导体 - 绝缘体 - 超导体约瑟夫逊隧道结及其方法
    • US5801393A
    • 1998-09-01
    • US840070
    • 1997-04-24
    • Gun-Yong SungJeong-Dae Suh
    • Gun-Yong SungJeong-Dae Suh
    • H01L39/22H01L39/24H01L29/06
    • H01L39/223H01L39/2496Y10S505/702Y10S505/728
    • A superconductor-insulator-superconductor Josephson tunnel junction, comprising: a single crystalline substrate having a perovskite crystal structure; a template layer formed of a b-axis oriented PBCO thin film on the substrate; and a trilayer structure consisting of a lower electrode, a barrier layer and an upper electrode, which serve as a superconductor, an insulator and a superconductor, respectively, the lower electrode and the upper electrode each being formed of an a-axis oriented YBCO superconducting thin film and having an oblique junction edge at an angle of 30.degree. to 70.degree., the barrier layer being formed of an insulating thin film between the two superconducting electrodes, can be operated at a low power with an exceptional speed in calculation and data processing.
    • 超导体 - 绝缘体 - 超导体约瑟夫逊隧道结,包括:具有钙钛矿晶体结构的单晶衬底; 在基板上由b轴取向的PBCO薄膜形成的模板层; 以及分别由用作超导体,绝缘体和超导体的下电极,阻挡层和上电极组成的三层结构,所述下电极和上电极各自由a轴取向的YBCO超导体 薄膜,并且在30°至70°的角度具有倾斜的接合边缘,阻挡层由两个超导电极之间的绝缘薄膜形成,可以在计算和数据处理中以非常高的速度以低功率运行 。
    • 10. 发明授权
    • Method for making a superconducting field-effect device with grain
boundary channel
    • 制造具有晶界通道的超导场效应装置的方法
    • US5846846A
    • 1998-12-08
    • US560962
    • 1995-11-20
    • Jeong-Dae SuhGun-Yong Sung
    • Jeong-Dae SuhGun-Yong Sung
    • H01L39/00H01L29/78H01L39/22H01L39/24H01L21/00
    • H01L39/2496H01L39/228
    • Disclosed is a method for making a superconducting field-effect device with a grain boundary channel, the method comprising the steps of depositing a first superconducting thin film on a substrate; patterning the first superconducting thin film to form a patterned superconducting thin film having an opening; depositing a template layer thereon; selectively etching back the template layer to form a patterned template layer; growing a second superconducting thin film to form a grain boundary therebetween; depositing an insulating layer on the second superconducting thin film to protect the second superconducting thin film from degrading in property in the air; selectively etching back the insulating layer to form a patterned insulating layer; forming a gate insulating layer on the patterned insulating layer; and coating metal electrodes thereon, source/drain being formed respectively on the etched portions, and a gate electrode being formed on the deposited portion of the gate insulating layer directly above the grain boundary. In the superconducting FET manufactured thus, since a gate electrode is formed directly above a grain boundary, current flowing between source and drain can be controlled by a voltage applied through an gate insulating layer. Also, since the grain boundary serving as a channel can be formed in a cheaper oxide crystal substrate by variation in a growing temperature of thin film without using an expensive by-crystal substrate, a high-temperature superconducting FET can be economically fabricated.
    • 公开了一种制造具有晶界通道的超导场效应器件的方法,该方法包括以下步骤:在衬底上沉积第一超导薄膜; 图案化第一超导薄膜以形成具有开口的图案化超导薄膜; 在其上沉积模板层; 选择性地蚀刻模板层以形成图案化的模板层; 生长第二超导薄膜以在其间形成晶界; 在所述第二超导薄膜上沉积绝缘层以保护所述第二超导薄膜不会降低空气中的性能; 选择性地蚀刻回绝缘层以形成图案化的绝缘层; 在所述图案化绝缘层上形成栅极绝缘层; 并在其上涂覆金属电极,分别在蚀刻部分上形成源极/漏极,以及形成在晶界正上方的栅极绝缘层的沉积部分上的栅电极。 在这样制造的超导FET中,由于栅电极直接形成在晶界之上,所以可以通过栅极绝缘层施加的电压来控制在源极和漏极之间流动的电流。 此外,由于可以通过在不使用昂贵的晶体基板的情况下通过薄膜的生长温度的变化而在较便宜的氧化物晶体基板中形成作为沟道的晶界,因此可以经济地制造高温超导FET。