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1. 发明申请

US20080058276A1 ALZHEIMER'S DISEASE THERAPEUTICS BASED ON PIN-1 CATALYZED CONFORMATIONAL CHANGES IN PHOSPHORYLATED AMYLOID PRECURSOR PROTEIN 审中-公开
标题翻译： ALZHEIMER的疾病治疗基于PIN-1催化的合成氨基酸前体蛋白的一致性变化
公开(公告)号：US20080058276A1
公开(公告)日：2008-03-06
申请号：US11623672
申请日：2007-01-16
申请人： Kun LU , Linda NICHOLSON , Lucia PASTORINO , Xiao ZHOU , Soumya DE
发明人： Kun LU , Linda NICHOLSON , Lucia PASTORINO , Xiao ZHOU , Soumya DE
IPC分类号： A61K31/70 , A61P25/28 , C12N5/06 , C12Q1/02 , G01N33/00
CPC分类号： A61K31/70 , G01N33/6896 , G01N2800/2821
摘要： The present invention is directed to inhibiting amyloidogenic processing of amyloid precursor protein, and/or inhibiting production of amyloid beta peptides. These methods can involve accelerating cis/trans isomerization of amyloid precursor protein at a phosphorylated serine/threonine-proline motif and/or contacting a cell with a compound that mimics the cis conformation of a phosphorylated serine/threonine-proline motif of an amyloid precursor protein. The present invention also relates to treating and/or preventing in a subject a degenerative neurological disease characterized by amyloidogenic processing of amyloid precursor protein and/or overproduction of amyloid beta peptide. This method involves administering an agent that accelerates cis/trans isomerization of amyloid precursor protein at a phosphorylated serine/threonine-proline motif and/or inhibits production of amyloid β peptides. Methods of screening for therapeutic agents effective in treating and/or preventing such diseases, methods of screening for biological molecules involved in the amyloidogenic pathway, and compounds that mimic the cis conformation of a phosphorylated serine/threonine-proline motif of an amyloid precursor protein are also disclosed.
摘要翻译：本发明涉及抑制淀粉样蛋白前体蛋白的淀粉样蛋白形成加工和/或抑制淀粉样蛋白β肽的产生。这些方法可以涉及在磷酸化丝氨酸/苏氨酸 - 脯氨酸基序上加速淀粉样蛋白前体蛋白的顺式/反式异构化和/或使细胞与模拟淀粉样蛋白前体蛋白的磷酸化丝氨酸/苏氨酸 - 脯氨酸基序的顺式构象的化合物接触。本发明还涉及在受试者中治疗和/或预防退行性神经疾病，其特征在于淀粉样蛋白前体蛋白的淀粉样蛋白生成加工和/或淀粉样蛋白β肽的过量产生。该方法包括施用在磷酸化丝氨酸/苏氨酸 - 脯氨酸基序上加速淀粉样蛋白前体蛋白的顺式/反式异构化的试剂和/或抑制淀粉状蛋白β肽的产生。筛选有效治疗和/或预防此类疾病的治疗剂的方法，筛选参与淀粉样蛋白生成途径的生物分子的方法，以及模拟淀粉样蛋白前体蛋白的磷酸化丝氨酸/苏氨酸 - 脯氨酸基序的顺式构象的化合物是：也披露。

2. 发明申请

US20100328539A1 METHOD AND APPARATUS FOR MEMORY REUSE IN IMAGE PROCESSING 审中-公开
标题翻译：图像处理中存储器重用的方法和装置
公开(公告)号：US20100328539A1
公开(公告)日：2010-12-30
申请号：US12493931
申请日：2009-06-29
申请人： Yan HUO , Lu WANG , Ka Man CHENG , Xiao ZHOU
发明人： Yan HUO , Lu WANG , Ka Man CHENG , Xiao ZHOU
IPC分类号： H04N5/00
CPC分类号： H04N19/433
摘要： This invention relates to a method of reusing data in memory for motion estimation. Only additional data is required to prepare reference block so as to reduce the data transfer to the memory. The additional data will be arranged with the existing data in the memory to provide the reference block. Then the data in the memory is read in a specific way to retrieve the reference block. Using this invention, the bandwidth requirement and internal memory can be greatly reduced without any additional logic operation.
摘要翻译：本发明涉及一种在存储器中重用数据进行运动估计的方法。仅需要额外的数据来准备参考块，以便减少到存储器的数据传输。附加数据将与存储器中的现有数据一起布置以提供参考块。然后以特定方式读取存储器中的数据以检索参考块。使用本发明，可以大大减少带宽需求和内部存储器，而无需任何额外的逻辑操作。

3. 发明申请

US20090161596A1 METHOD AND SYSTEM FOR TRANSMITTING MULTIMEDIA BROADCAST/MULTICAST SERVICE 审中-公开
标题翻译：用于发送多媒体广播/多媒体服务的方法和系统
公开(公告)号：US20090161596A1
公开(公告)日：2009-06-25
申请号：US12394895
申请日：2009-02-27
申请人： Junwei WANG , Xiao ZHOU
发明人： Junwei WANG , Xiao ZHOU
IPC分类号： H04H20/71
CPC分类号： H04L12/189 , H04L12/1863 , H04W72/005
摘要： A method for transmitting multimedia broadcast/multicast service includes: checking whether packet loss occurs during a transmission process of the multimedia broadcast/multicast service; and notifying, upon checking a packet loss, a physical layer not to transmit any data over a time and frequency resource used for transmitting the lost packet. A system for transmitting multimedia broadcast/multicast service is also provided. The method and system realizes checking and handling the packet loss during transmission process of MBMS service in time, effectively prevents errors from spreading, guarantees that terminals can receive MBMS service data correctly and further ensures smooth radio combining in the physical layer.
摘要翻译：一种用于发送多媒体广播/组播业务的方法，包括：检查在多媒体广播/组播业务的传输过程中是否发生分组丢失; 并且在检查分组丢失时通知不在用于传输丢失分组的时间和频率资源上传输任何数据的物理层。还提供了一种用于传输多媒体广播/组播服务的系统。该方法和系统及时实现了MBMS业务传输过程中的丢包检测和处理，有效防止了扩频误差，保证了终端可以正确接收MBMS业务数据，进一步保证了物理层的无线组合。

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