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    • 3. 发明授权
    • Polyester block copolymer and elastic yarn composed thereof
    • 聚酯嵌段共聚物和由其组成的弹性丝
    • US5384184A
    • 1995-01-24
    • US128314
    • 1993-09-28
    • Noritsugu SaikiToshitsugu MatsukiMasayuki Hayashi
    • Noritsugu SaikiToshitsugu MatsukiMasayuki Hayashi
    • C08G63/181C08G63/688C08G63/692D03D15/08D03D15/12
    • D03D15/08C08G63/181C08G63/6886C08G63/6926D03D15/12Y10T442/413
    • A polyester block copolymer having an inherent viscosity of at least 0.6, which comprises (A) 30 to 90% by weight of polyester segments comprising a benzenedicarboxylic acid as the main acid component and a diol having 5 to 12 carbon atoms between the hydroxyl groups as the main glycol component and (B) 70 to 10% by weight of polyester segments comprising an aromatic dicarboxylic acid as the main acid component and ethylene glycol, trimethylene glycol, tetramethylene glycol or 1,4-cyclohexane dimethanol as the main glycol component, wherein (i) when a polyester having an inherent viscosity of at least 0.6 is formed by polycondensation of the components constituting the polyester segments (A), the melting point of the obtained polyester is lower than 50.degree. C. or the obtained polyester is amorphous, and (ii) when a polyester having an inherent viscosity of at least 0.6 is formed by polycondensation of the components constituting the polyester segments (B), the melting point of the polyester is higher than 180.degree. C. This polyester block copolymer provides an elastic yarn having a high elastic recovery and a high heat resistance.
    • 具有至少0.6的特性粘度的聚酯嵌段共聚物,其包含(A)30至90重量%的包含苯二甲酸作为主要酸组分的聚酯链段和羟基之间具有5至12个碳原子的二醇作为 主要二元醇组分和(B)70至10重量%的包含芳族二羧酸作为主要酸组分的聚酯链段和乙二醇,三亚甲基二醇,1,4-丁二醇或1,4-环己烷二甲醇作为主要二醇组分,其中 (i)当通过构成聚酯链段(A)的组分的缩聚形成具有至少0.6的特性粘度的聚酯时,所得聚酯的熔点低于50℃,或所得聚酯是无定形的, 和(ii)当通过构成聚酯链段(B)的组分的缩聚形成特性粘度至少为0.6的聚酯时,聚合物的熔点 ster高于180℃。该聚酯嵌段共聚物提供了具有高弹性回复性和高耐热性的弹性纱线。
    • 8. 发明授权
    • Immobilization of biologically active substances with a polyphosphazene
carrier
    • 用聚磷腈载体固定生物活性物质
    • US5380658A
    • 1995-01-10
    • US121909
    • 1993-09-16
    • Toshitsugu MatsukiNoritsugu SaikiShingo Emi
    • Toshitsugu MatsukiNoritsugu SaikiShingo Emi
    • A61K47/48C08G79/02C12N11/06C07K17/00G01N33/549
    • A61K47/48223C08G79/025Y10S435/803Y10S435/815Y10S530/815Y10S530/816
    • A phosphazene polymer carrier is prepared that has functional groups capable of binding a biologically active substance such as an enzyme or antibody and groups which are non-reactive and hydrophilic. A bifunctional aldehyde is reacted with primary amino groups of a shaped phosphazene polymer to form side chains having aldehyde groups, an amino group-containing compound is reacted with a portion of the aldehyde groups to produce the groups that are non-reactive and hydrophilic, and aldehyde groups not reacted are capable of binding a biologically active substance. The phosphazene polymer may be crosslinked prior to reacting with the bifunctional aldehyde. In another embodiment, a protecting agent is reacted with a portion of the aldehyde groups to block the aldehyde groups, imino bonds are reduced, a compound having an amino group is reacted with aldehyde groups not blocked to form the groups which are non-reactive and hydrophilic, and the protecting agent is removed to provide aldehyde groups capable of binding a biologically active substance. The non-reactive and hydrophilic groups may also be formed by reacting primary amino groups with formaldehyde or by diazotizing primary amino groups of the polymer followed by hydrolysis to form hydroxyl groups. A biologically active substance immobilized on the polymer can be used to separate a substance that has affinity for the immobilized biologically active substance.
    • 制备具有能够结合生物活性物质如酶或抗体的官能团的磷腈聚合物载体和非反应性和亲水性的基团。 双官能醛与成形磷腈聚合物的伯氨基反应形成具有醛基的侧链,含氨基的化合物与一部分醛基反应产生非反应性和亲水性的基团,以及 未反应的醛基能够结合生物活性物质。 磷腈聚合物可以在与双官能醛反应之前进行交联。 在另一个实施方案中,保护剂与一部分醛基反应以阻断醛基,亚氨基键被还原,具有氨基的化合物与不被阻断的醛基反应形成非反应性基团, 亲水,并除去保护剂以提供能够结合生物活性物质的醛基。 非反应性和亲水性基团也可以通过使伯氨基与甲醛反应或通过重氮化聚合物的伯氨基然后进行水解形成羟基而形成。 固定在聚合物上的生物活性物质可用于分离对固定的生物活性物质具有亲和性的物质。