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1. 发明申请

US20140311159A1 VARIABLE NOZZLE MECHANISM 审中-公开
标题翻译：可变的喷嘴机构
公开(公告)号：US20140311159A1
公开(公告)日：2014-10-23
申请号：US14358385
申请日：2012-11-06
申请人： Hiroaki Ikegami , Koichi Yonezawa , Tsuyoshi Uesugi , Manabu Ishikawa
发明人： Hiroaki Ikegami , Koichi Yonezawa , Tsuyoshi Uesugi , Manabu Ishikawa
IPC分类号： F02C7/00
CPC分类号： F02C7/00 , F01D17/165 , F05D2220/40 , F05D2230/642 , F05D2250/42
摘要： A variable nozzle mechanism applied to a turbocharger includes a pair of annular plates located between a scroll passage and a turbine chamber such that the plates are apart from each other in a direction along an axis; a coupling portion which couples the plates; a plurality of variable nozzles which are provided between the plates so as to open and close, and which change a flow speed of exhaust gas blown onto a turbine wheel when an opening degree of the variable nozzles is changed; and an urging portion which urges the plates in the direction along the axis to press one of the plates against a contacted object. The one of the plates includes a contact face which is in contact with the contacted object, and the contact face is located on an action line along which an urging force of the urging portion acts.
摘要翻译：应用于涡轮增压器的可变喷嘴机构包括位于涡旋通道和涡轮室之间的一对环形板，使得板沿着轴线的方向彼此分开; 连接板的联接部分; 多个可变喷嘴，其设置在所述板之间以打开和关闭，并且当所述可变喷嘴的开度改变时，改变吹送到涡轮机叶轮上的废气的流速; 以及沿着轴线的方向推动板的推压部分将板中的一个压靠在接触物体上。所述板之一包括与被接触物体接触的接触面，并且所述接触面位于所述推动部分的作用力作用的作用线上。

2. 发明授权

US07249454B2 Fuel injection control apparatus and fuel injection control method for internal combustion engine 失效
标题翻译：用于内燃机的燃料喷射控制装置和燃料喷射控制方法
公开(公告)号：US07249454B2
公开(公告)日：2007-07-31
申请号：US10985986
申请日：2004-11-12
申请人： Masaharu Ichise , Toshimi Kashiwagura , Shinichiro Nogawa , Koichi Yonezawa
发明人： Masaharu Ichise , Toshimi Kashiwagura , Shinichiro Nogawa , Koichi Yonezawa
IPC分类号： F01N3/00
CPC分类号： F02D41/0235 , F01N13/011 , F01N2430/00 , F01N2430/06 , F02B2075/125 , F02D41/3094 , F02D2041/0265 , F02D2200/0802 , F02M69/044 , F02M69/045 , F02M69/046 , Y02T10/123
摘要： An internal combustion engine includes an in-cylinder injection valve and an intake passage injection valve. A control apparatus of the engine determines whether a catalyst located in an exhaust passage is in an overtemperature condition. When the catalyst is determined to be in the overtemperature condition, the control apparatus controls the injection valves to increase the amount fuel supplied to the cylinder compared to a case where the catalyst is determined not to be in the overtemperature condition. The control apparatus sets a mode for causing the injection valves to increase the amount of supplied fuel according to an operational state of the engine. For example, in a case where the component is determined to be in the overtemperature condition when the engine is operating in a fuel injection mode in which fuel is injected at least from the in-cylinder injection valve, at least the intake passage injection valve performs fuel injection for increasing the supplied fuel. Therefore, the catalyst is reliably prevented from being overheated.
摘要翻译：内燃机包括缸内喷射阀和进气通道喷射阀。发动机的控制装置确定位于排气通道中的催化剂是否处于过热状态。当确定催化剂处于过热状态时，控制装置控制喷射阀以增加与催化剂不处于过热状态的情况相比，供给到气缸的燃料量。控制装置根据发动机的运转状态设定使喷射阀增加供油量的模式。例如，在发动机至少从缸内喷射阀喷射燃料的燃料喷射模式下进行运转的情况下，判定为处于过热状态的情况下，至少进气通路喷射阀进行用于增加供应燃料的燃料喷射。因此，可靠地防止催化剂过热。

3. 发明申请

US20050109020A1 Fuel injection control apparatus and fuel injection control method for internal combustion engine 失效
标题翻译：用于内燃机的燃料喷射控制装置和燃料喷射控制方法
公开(公告)号：US20050109020A1
公开(公告)日：2005-05-26
申请号：US10985962
申请日：2004-11-12
申请人： Masaharu Ichise , Toshimi Kashiwagura , Shinichiro Nogawa , Koichi Yonezawa
发明人： Masaharu Ichise , Toshimi Kashiwagura , Shinichiro Nogawa , Koichi Yonezawa
IPC分类号： F02D41/30 , F01N9/00 , F01N13/04 , F02B75/12 , F02D41/02 , F02D41/22 , F02M69/04
CPC分类号： F02D41/0235 , F01N13/011 , F01N2430/00 , F01N2430/06 , F02B2075/125 , F02D41/3094 , F02D2041/0265 , F02D2200/0802 , F02M69/044 , F02M69/045 , F02M69/046 , Y02T10/123
摘要： An internal combustion engine includes an in-cylinder injection valve and an intake passage injection valve. A control apparatus of the engine determines whether the temperature of a component located in the exhaust passage is higher than or equal to a predetermined temperature. When the temperature of the component is higher than or equal to the predetermined temperature, the control apparatus increases, without changing the total amount of fuel supplied to the cylinder, the ratio of a fuel injection amount of the intake passage injection valve to a fuel injection amount of the in-cylinder injection valve compared to a case where the temperature of the component is not higher than or equal to the predetermined temperature. Therefore, the catalyst is reliably prevented from being overheated, while preventing the fuel economy from deteriorating.
摘要翻译：内燃机包括缸内喷射阀和进气通道喷射阀。发动机的控制装置确定位于排气通道中的部件的温度是否高于或等于预定温度。当部件的温度高于或等于预定温度时，控制装置在不改变供给到气缸的燃料总量的情况下增加了进气通道喷射阀的燃料喷射量与燃料喷射的比率与组件的温度不高于或等于预定温度的情况相比，缸内喷射阀的量。因此，可以可靠地防止催化剂过热，同时防止燃料经济性恶化。

4. 发明授权

US06450147B2 Fuel pressure control apparatus of internal combustion engine 失效
标题翻译：内燃机燃油压力控制装置
公开(公告)号：US06450147B2
公开(公告)日：2002-09-17
申请号：US09814872
申请日：2001-03-23
申请人： Takayuki Demura , Hiroyuki Mizuno , Koichi Yonezawa
发明人： Takayuki Demura , Hiroyuki Mizuno , Koichi Yonezawa
IPC分类号： F02M3706
CPC分类号： F02D41/3845 , F02D41/1482 , F02D2041/1409 , F02D2041/1422 , F02D2250/31
摘要： A fuel pressure control apparatus and method controls a pressure of fuel that is delivered from a fuel pump to a fuel pipe in an internal combustion engine of a vehicle. A controller of the fuel pressure control apparatus calculates a controlled variable based on at least an integral term that is updated in accordance with a difference between an actual fuel pressure in the fuel pipe and a target value thereof; and controls an amount of the fuel delivered from the fuel pump in a feedback manner, using the controlled variable, so that the actual fuel pressure approaches the target value. During the control of the fuel pressure, the controller inhibits updating of the integral term to a value that results in an increase in the amount of the fuel delivered from the fuel pump, when the amount of the fuel delivered is approximate to or equal to a maximum value thereof.
摘要翻译：燃料压力控制装置和方法控制从燃料泵输送到车辆的内燃机中的燃料管的燃料的压力。燃料压力控制装置的控制器基于至少一个根据燃料管道中的实际燃料压力与其目标值之间的差异更新的积分项来计算控制变量; 并且使用所述受控变量来控制从所述燃料泵输送的燃料的量，以使得所述实际燃料压力接近所述目标值。在燃料压力的控制期间，当所输送的燃料量近似等于或等于一个时，控制器禁止将积分项更新为导致从燃料泵输送的燃料量增加的值最大值。

5. 发明授权

US09695780B2 Internal combustion engine 有权
公开(公告)号：US09695780B2
公开(公告)日：2017-07-04
申请号：US14365355
申请日：2012-03-05
申请人： Takahiro Sadamitsu , Atsushi Nakagaki , Osamu Maeda , Tomoyuki Isogai , Tatsuo Iida , Koichi Yonezawa
发明人： Takahiro Sadamitsu , Atsushi Nakagaki , Osamu Maeda , Tomoyuki Isogai , Tatsuo Iida , Koichi Yonezawa
IPC分类号： F02B47/08 , F02M25/07 , F02B39/00 , F01M13/02 , F01D17/10 , F02B37/16 , F02M25/08
CPC分类号： F02M26/09 , F01D17/105 , F01M13/022 , F01M2013/027 , F02B37/16 , F02B39/00 , F02M25/08 , F05D2220/40 , F05D2260/14 , F05D2260/606 , Y02T10/144
摘要： A second recirculation passage recirculates blow-by gas at an upstream section, which is upstream of an impeller of a turbocharger in an intake passage. A first passage branches and extends from a downstream section, which is downstream of the impeller in the intake passage. A second passage that forms part of the second recirculation passage connects the first passage and the upstream section to each other. A third passage, which is provided separately from the second passage, connects the first passage and the upstream section to each other. A change mechanism changes, in different manners, the flow rate of compressed gas recirculating to the upstream section through the second passage, and the flow rate of compressed gas recirculating to the upstream section through the third passage.

6. 发明申请

US20050235959A1 Apparatus and method for controlling fuel injection in internal combustion engine 失效
标题翻译：用于控制内燃机燃油喷射的装置和方法
公开(公告)号：US20050235959A1
公开(公告)日：2005-10-27
申请号：US11109826
申请日：2005-04-20
申请人： Shinji Sadakane , Koichi Yonezawa
发明人： Shinji Sadakane , Koichi Yonezawa
IPC分类号： F02N11/08 , F02B7/00 , F02B7/02 , F02B17/00 , F02B23/10 , F02B75/12 , F02D41/04 , F02D41/06 , F02D41/34 , F02D45/00 , F02M51/00 , F02M69/00 , F02M69/04
CPC分类号： F02D41/062 , F02B7/02 , F02B23/104 , F02B2075/125 , F02B2275/16 , F02D41/3094 , F02N19/00 , Y02T10/123
摘要： An internal combustion engine includes an in-cylinder injector for injecting fuel into a combustion chamber of the engine and an intake system injector for injecting fuel into an intake system connected to the combustion chamber. In a starting state of the engine, an electronic control unit (ECU) causes the in-cylinder injector to perform only the initial injection to the combustion chamber, and causes the intake system injector to perform fuel injections after the initial injection. As a result, favorable engine startability is ensured, and the emission of unburned components is suppressed in the engine starting state.
摘要翻译：内燃机包括用于将燃料喷射到发动机的燃烧室中的缸内喷射器和用于将燃料喷射到连接到燃烧室的进气系统中的进气系统喷射器。在发动机的起动状态下，电子控制单元（ECU）使缸内喷射器仅对燃烧室进行初始喷射，并使得进气系统喷射器在初始喷射后进行燃料喷射。结果，确保良好的发动机起动性，并且在发动机起动状态下抑制未燃烧部件的排出。

7. 发明授权

US08106190B2 2-aminobenzamide derivatives 有权
标题翻译： 2-氨基苯甲酰胺衍生物
公开(公告)号：US08106190B2
公开(公告)日：2012-01-31
申请号：US12094298
申请日：2006-11-29
申请人： Takahiro Kuramochi , Ryoji Hirabayashi , Yohei Koganemaru , Ryosuke Munakata , Koichi Yonezawa , Tetsuo Kiso
发明人： Takahiro Kuramochi , Ryoji Hirabayashi , Yohei Koganemaru , Ryosuke Munakata , Koichi Yonezawa , Tetsuo Kiso
IPC分类号： C07D265/30 , C07D265/36 , C07D405/04 , C07D413/00
CPC分类号： C07D295/135 , A61K31/167 , C07C37/18 , C07C237/40 , C07C2601/14 , C07C2602/10 , C07D207/09 , C07D207/14 , C07D209/34 , C07D209/48 , C07D209/96 , C07D211/58 , C07D213/38 , C07D213/74 , C07D213/80 , C07D215/227 , C07D215/38 , C07D217/02 , C07D265/36 , C07D277/64 , C07D279/16 , C07D295/13 , C07D295/185 , C07D307/14 , C07D307/22 , C07D309/14 , C07D319/12 , C07D319/18 , C07D321/10 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D405/14 , C07D413/04 , C07D413/12 , C07D417/12 , C07D453/02 , C07C39/27
摘要： To provide a novel and excellent agent for treating or preventing nociceptive pain, neuropathic pain, cancer pain, headache, bladder function disorder and the like, based on the inhibitory action on the capsaicin receptor VR1 activation.The present invention was accomplished by confirming that a benzamide derivative characterized by the possession of a benzene ring in which a single ring is condensed on the nitrogen atom of amido group and possession of a lower alkylamino or an amino group substituted with a ring group at the neighboring position of said amido group has a strong inhibitory action on VR1 activation and excellent pharmacological actions based on this and by finding that it can become an excellent agent for treating or preventing VR1-involved diseases such as nociceptive pain, neuropathic pain, cancer pain, headache, bladder function disorder and the like.
摘要翻译：基于对辣椒素受体VR1活化的抑制作用，提供用于治疗或预防伤害性疼痛，神经性疼痛，癌症疼痛，头痛，膀胱功能障碍等的新颖优异的药剂。本发明是通过确认苯甲酰胺衍生物，其特征在于具有苯环，其中单环在酰氨基的氮原子上缩合，并且具有低级烷基氨基或被环基取代的氨基所述酰胺基的相邻位置对VR1的活化具有强烈的抑制作用，并且基于此起到优异的药理作用，并且发现其可以成为治疗或预防VR1涉及的疾病如伤害性疼痛，神经性疼痛，癌症疼痛，头痛，膀胱功能障碍等。

8. 发明申请

US20100168154A1 1-SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUND 有权
标题翻译： 1-取代的四氢喹啉化合物
公开(公告)号：US20100168154A1
公开(公告)日：2010-07-01
申请号：US12600503
申请日：2008-05-20
申请人： Jun-Ichi Shishikura , Makoto Inoue , Takashi Ogiyama , Koichi Yonezawa , Susumu Yamaki , Kazuhiro Yokoyama , Shuichirou Kakimoto , Hidetsugu Okada
发明人： Jun-Ichi Shishikura , Makoto Inoue , Takashi Ogiyama , Koichi Yonezawa , Susumu Yamaki , Kazuhiro Yokoyama , Shuichirou Kakimoto , Hidetsugu Okada
IPC分类号： A61K31/437 , C07D217/04 , C07D491/04 , A61K31/4725 , A61K31/472 , A61P25/00
CPC分类号： C07D217/04 , C07D217/14 , C07D217/16 , C07D221/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D405/06 , C07D491/06
摘要： Provided is a compound useful as an N-type Ca2+ channel blocker. As a result of intensive studies of compounds having an action of blocking N-type Ca2+ channels, the present inventors found that a tetrahydroisoquinoline compound of the present invention having a substituent at the 1-position has an action of blocking the N-type Ca2+ channels, an antinociceptive pain action, an antineuropathic pain action, an abdominal pain-inhibitory action and an opioid-induced constipation-improving action, and the present invention has been completed based on these findings. The compound of the present invention can be used as a pharmaceutical composition for preventing and/or treating various pains such as neuropathic pain and nociceptive pain, headaches such as migraine and cluster headache, central nervous system diseases such as anxiety, depression, epilepsy, cerebral stroke and restless legs syndrome, abdominal symptoms such as abdominal pain and abdominal distension, stool abnormalities such as diarrhea and constipation, digestive system diseases such as irritable bowel syndrome, urinary system diseases such as overactive bladder and interstitial cystitis, etc.
摘要翻译：提供可用作N型Ca2 +通道阻断剂的化合物。通过对具有阻塞N型Ca 2+通道作用的化合物的深入研究，本发明人发现在1位具有取代基的本发明的四氢异喹啉化合物具有阻断N型Ca 2+通道的作用抗痛知性疼痛作用，抗神经病性疼痛作用，腹痛抑制作用和阿片样物质诱导的便秘改善作用，并且基于这些发现完成了本发明。本发明的化合物可以用作预防和/或治疗诸如神经性疼痛和伤害性疼痛，头痛如偏头痛和丛集性头痛，中枢神经系统疾病如焦虑，抑郁，癫痫，脑的各种疼痛的药物组合物中风和不宁腿综合症，腹痛，腹胀等腹部症状，腹泻便秘等粪便异常，肠易激综合征等消化系统疾病，膀胱过多膀胱炎，间质性膀胱炎等泌尿系统疾病等。

9. 发明授权

US07082926B2 Apparatus and method for controlling fuel injection in internal combustion engine 失效
标题翻译：用于控制内燃机燃油喷射的装置和方法
公开(公告)号：US07082926B2
公开(公告)日：2006-08-01
申请号：US11109826
申请日：2005-04-20
申请人： Shinji Sadakane , Koichi Yonezawa
发明人： Shinji Sadakane , Koichi Yonezawa
IPC分类号： F02B7/00 , F02B7/02
CPC分类号： F02D41/062 , F02B7/02 , F02B23/104 , F02B2075/125 , F02B2275/16 , F02D41/3094 , F02N19/00 , Y02T10/123
摘要： An internal combustion engine includes an in-cylinder injector for injecting fuel into a combustion chamber of the engine and an intake system injector for injecting fuel into an intake system connected to the combustion chamber. In a starting state of the engine, an electronic control unit (ECU) causes the in-cylinder injector to perform only the initial injection to the combustion chamber, and causes the intake system injector to perform fuel injections after the initial injection. As a result, favorable engine startability is ensured, and the emission of unburned components is suppressed in the engine starting state.
摘要翻译：内燃机包括用于将燃料喷射到发动机的燃烧室中的缸内喷射器和用于将燃料喷射到连接到燃烧室的进气系统中的进气系统喷射器。在发动机的起动状态下，电子控制单元（ECU）使缸内喷射器仅对燃烧室进行初始喷射，并使得进气系统喷射器在初始喷射后进行燃料喷射。结果，确保良好的发动机起动性，并且在发动机起动状态下抑制未燃烧部件的排出。

10. 发明授权

US08263607B2 1-substituted tetrahydroisoquinoline compound 有权
标题翻译： 1-取代的四氢异喹啉化合物
公开(公告)号：US08263607B2
公开(公告)日：2012-09-11
申请号：US12600503
申请日：2008-05-20
申请人： Jun-ichi Shishikura , Makoto Inoue , Takashi Ogiyama , Koichi Yonezawa , Susumu Yamaki , Kazuhiro Yokoyama , Shuichirou Kakimoto , Hidetsugu Okada
发明人： Jun-ichi Shishikura , Makoto Inoue , Takashi Ogiyama , Koichi Yonezawa , Susumu Yamaki , Kazuhiro Yokoyama , Shuichirou Kakimoto , Hidetsugu Okada
IPC分类号： C07D217/04 , C07D491/04 , A61K31/472
CPC分类号： C07D217/04 , C07D217/14 , C07D217/16 , C07D221/20 , C07D401/04 , C07D401/06 , C07D401/12 , C07D405/06 , C07D491/06
摘要： Provided is a compound useful as an N-type Ca2+ channel blocker. As a result of intensive studies of compounds having an action of blocking N-type Ca2+ channels, the present inventors found that a tetrahydroisoquinoline compound of the present invention having a substituent at the 1-position has an action of blocking the N-type Ca2+ channels, an antinociceptive pain action, an antineuropathic pain action, an abdominal pain-inhibitory action and an opioid-induced constipation-improving action, and the present invention has been completed based on these findings. The compound of the present invention can be used as a pharmaceutical composition for preventing and/or treating various pains such as neuropathic pain and nociceptive pain, headaches such as migraine and cluster headache, central nervous system diseases such as anxiety, depression, epilepsy, cerebral stroke and restless legs syndrome, abdominal symptoms such as abdominal pain and abdominal distension, stool abnormalities such as diarrhea and constipation, digestive system diseases such as irritable bowel syndrome, urinary system diseases such as overactive bladder and interstitial cystitis, etc.
摘要翻译：提供可用作N型Ca2 +通道阻断剂的化合物。通过对具有阻塞N型Ca 2+通道作用的化合物的深入研究，本发明人发现在1位具有取代基的本发明的四氢异喹啉化合物具有阻断N型Ca 2+通道的作用抗痛知性疼痛作用，抗神经病性疼痛作用，腹痛抑制作用和阿片样物质诱导的便秘改善作用，并且基于这些发现完成了本发明。本发明的化合物可以用作预防和/或治疗诸如神经性疼痛和伤害性疼痛，头痛如偏头痛和丛集性头痛，中枢神经系统疾病如焦虑，抑郁，癫痫，脑的各种疼痛的药物组合物中风和不宁腿综合症，腹痛，腹胀等腹部症状，腹泻便秘等粪便异常，肠易激综合征等消化系统疾病，膀胱过多膀胱炎，间质性膀胱炎等泌尿系统疾病等。

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