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1. 发明授权

US4883822A Agent for regulating the motional function of gastrointestinal tract 失效
标题翻译：调节胃肠道运动功能的药剂
公开(公告)号：US4883822A
公开(公告)日：1989-11-28
申请号：US248087
申请日：1988-09-23
申请人： Kohtaro Matsuo , Youichirou Ezaki , Akihiro Tobe , Satoshi Yamazaki , Kozue Enda , Mariko Kitsukawa
发明人： Kohtaro Matsuo , Youichirou Ezaki , Akihiro Tobe , Satoshi Yamazaki , Kozue Enda , Mariko Kitsukawa
IPC分类号： A61K31/12 , A61P1/00 , A61P1/14 , C07C49/675 , C07C49/755
CPC分类号： A61K31/12
摘要： An agent for regulating the motional function of the gastrointestinal tract, which contains as an active ingredient a 41-metyl-4,4a,9,10-tetrahydro-2(3H)-phenanthrenone derivative represented by the following formula I; ##STR1## wherein R.sup.1 represents a hydrogen atom, an alkyl group or an alkoxy group and R.sup.2 represents a hydrogen atom or an alkyl group.

2. 发明授权

US4977151A Ethanone oximes and pharmaceutical compositions thereof 失效
标题翻译：乙酮肟及其药物组合物
公开(公告)号：US4977151A
公开(公告)日：1990-12-11
申请号：US501591
申请日：1990-03-29
申请人： Shinichiro Fujimori , Satoshi Yamazaki , Mamoru Sugano , Makoto Kawamura , Kunihiro Ninomiya , Akihiro Tobe , Issei Nitta
发明人： Shinichiro Fujimori , Satoshi Yamazaki , Mamoru Sugano , Makoto Kawamura , Kunihiro Ninomiya , Akihiro Tobe , Issei Nitta
IPC分类号： C07D295/12 , A61K31/34 , A61K31/343 , A61K31/40 , A61K31/415 , A61K31/445 , A61K31/495 , A61K31/54 , A61K31/5415 , A61P1/04 , C07D233/61 , C07D279/18 , C07D279/30 , C07D295/125 , C07D307/91 , C07D333/76 , C07D339/08 , C07D521/00
CPC分类号： C07D307/91 , C07D231/12 , C07D233/56 , C07D249/08 , C07D279/30 , C07D295/125 , C07D333/76 , C07D339/08
摘要： Ethanone oximes represented by the following general formula: ##STR1## wherein R.sup.1 represents a cycloalkyl group, aryl group, aralkyl group, aryloxy group, aralkyloxy group, arylthio group or aryl sulfonyl group, those groups being optionally substituted with a substituent selected from an alkyl group having 1 to 3 carbon atoms, an alkoxy group having 1 to 3 carbon atoms and a halogen atom, piperidino group, piperazino group, 4-alkyl substituted piperazino group, imidazolyl group 4-alkyl substituted imidazolyl group or substituted amino group,R.sup.2 represents a hydrogen atom or an alkoxy group having 1 to 3 carbon atoms, andR.sup.3 represents a piperidino group, piperazino group or 4-alkyl substituted piperazino group, orR.sup.1 and R.sup.2 together with a phenyl group to which they are attached may form a phenothiazin-2-yl group, N-acetyl-phenothiazin-2-yl group, thianthren-2-yl group, dibenzothiophen-3-yl group, dibenzofuran-3-yl group or a group of the formula: ##STR2## wherein R.sup.4 represents a hydrogen atom or an alkyl group having 1 to 3 carbon atoms, or a pharmaceutically acceptable acid addition salts thereof are disclosed. They are a potent antiulcer agent.

3. 发明授权

US5556851A Cinnoline-3-carboxylic acid derivatives 失效
公开(公告)号：US5556851A
公开(公告)日：1996-09-17
申请号：US286220
申请日：1994-08-05
申请人： Akira Maruyama , Shigeru Ogawa , Satoshi Yamazaki , Akihiro Tobe
发明人： Akira Maruyama , Shigeru Ogawa , Satoshi Yamazaki , Akihiro Tobe
IPC分类号： A61K31/50 , A61P1/00 , A61P1/08 , A61P25/04 , A61P25/20 , C07D403/12 , C07D451/04 , C07D451/06 , C07D453/02 , C07D471/08 , C07D487/08 , A61K31/55
CPC分类号： C07D451/04 , C07D451/06 , C07D453/02
摘要： A novel cinnoline derivative having an antagonistic activity against serotonin 5-HT.sub.3 receptor, its pharmaceutically acceptable salts, its N-oxide derivatives or solvates thereof, and pharmaceutical formulations containing the same for the prevention and/or treatment of various disorders such as nausea and/or emesis caused by anticancer drugs or X-ray treatment, central nervous disorders such as anxiety and/or neuropathy, gastroenteric diseases such as indigestion, chronic gastritis, digestive ulcer, irritable bowel syndromes and the like, hemicrania, cluster headache, trigeminal neuralgia, arrhythmia and the like.

4. 发明授权

US4933344A Ethanone oximes and pharmaceutical compositions thereof 失效
公开(公告)号：US4933344A
公开(公告)日：1990-06-12
申请号：US239169
申请日：1988-08-31
申请人： Shinichiro Fujimori , Satoshi Yamazaki , Mamoru Sugano , Makoto Kawamura , Kunihiro Ninomiya , Akihiro Tobe , Issei Nitta
发明人： Shinichiro Fujimori , Satoshi Yamazaki , Mamoru Sugano , Makoto Kawamura , Kunihiro Ninomiya , Akihiro Tobe , Issei Nitta
IPC分类号： C07D295/12 , A61K31/34 , A61K31/343 , A61K31/40 , A61K31/415 , A61K31/445 , A61K31/495 , A61K31/54 , A61K31/5415 , A61P1/04 , C07D233/61 , C07D279/18 , C07D279/30 , C07D295/125 , C07D307/91 , C07D333/76 , C07D339/08 , C07D521/00
CPC分类号： C07D307/91 , C07D231/12 , C07D233/56 , C07D249/08 , C07D279/30 , C07D295/125 , C07D333/76 , C07D339/08
摘要： Ethanone oximes represented by the following general formula: ##STR1## wherein R.sup.1 represents a cycloalkyl group, aryl group, aralkyl group, aryloxy group, aralkyloxy group, arylthio group or aryl sulfonyl group, those groups being optionally substituted with a substituent selected from an alkyl group having 1 to 3 carbon atoms, an alkoxy group having 1 to 3 carbon atoms and a halogen atom, piperidino group, piperazino group, 4-alkyl substituted piparazino group, imidazolyl group, 4-alkyl substituted imidazolyl group or substituted amino group,R.sup.2 represents a hydrogen atom or an alkoxy group having 1 to 3 carbon atoms, andR.sup.3 represents a piperidino group, piperazino group or 4-alkyl substituted piperazino group, orR.sup.1 and R.sup.2 together with a phenyl group to which they are attached may form a phenothiazin-2-yl group, N-acetyl-phenothiazin-2-yl group, thianthren-2-yl group, dibenzothiophen-3-yl group, dibenzofuran-3-yl group or a group of the formula: ##STR2## wherein R.sup.4 represents a hydrogen atom or an alkyl group having 1 to 3 carbon atoms, or a pharmaceutically acceptable acid addition salts thereof are disclosed. They are a potent antiulcer agent.

5. 发明授权

US5352685A Thieno[3,2-b]pyridine derivatives 失效
标题翻译：噻吩并[3,2-b]吡啶衍生物
公开(公告)号：US5352685A
公开(公告)日：1994-10-04
申请号：US29551
申请日：1993-03-11
申请人： Akira Maruyama , Shigeru Ogawa , Satoshi Yamazaki , Akihiro Tobe
发明人： Akira Maruyama , Shigeru Ogawa , Satoshi Yamazaki , Akihiro Tobe
IPC分类号： A61K31/435 , A61P1/00 , A61P1/08 , A61P9/00 , A61P25/04 , A61P25/20 , C07D495/04 , C07D519/00
CPC分类号： C07D519/00
摘要： The thieno[3.2-b]pyridine derivative of the present invention promote the gastric emptying in male ddy mice and the gastric contraction in dogs sutured with a strain-gauge transducer. It is believed that the derivatives have the action to enhance gastric motor action and gastric emptying. Therefore, the compound of the present invention are effective for the prevention and therapeutical treatment of the symptoms caused by gastric hypanakinesis, such as heartburn, abdominal distension feeling, anorexia, unpleasant feeling on upper abdomen, abdominalgia, nausea, vomiting, etc. caused by the underlying diseases such as acute and chronic gastritis, stomach and duodenum ulcer, gastroneurosis, gastroptosis, etc. The present invention also encompasses a pharmaceutical composition containing as the effective ingredient a compound of the present invention, and a method for producing the same.
摘要翻译：本发明的噻吩并[3,2-b]吡啶衍生物促进雄性ddy小鼠胃排空，并用应变计换能器缝合狗的胃收缩。据信这些衍生物具有增强胃运动作用和胃排空的作用。因此，本发明的化合物可有效预防和治疗由胃灼热引起的症状，例如胃灼热，腹胀，厌食，上腹部不适感，腹痛，恶心，呕吐等引起的症状。基础疾病如急性和慢性胃炎，胃和十二指肠溃疡，胃肠炎，胃食管狭窄等。本发明还包括含有本发明化合物作为有效成分的药物组合物及其制备方法。

6. 发明授权

US5391549A Cinnoline-3-carboxylic acid derivatives 失效
标题翻译：噌啉-3-羧酸衍生物
公开(公告)号：US5391549A
公开(公告)日：1995-02-21
申请号：US29431
申请日：1993-03-10
申请人： Akira Maruyama , Shigeru Ogawa , Satoshi Yamazaki , Akihiro Tobe
发明人： Akira Maruyama , Shigeru Ogawa , Satoshi Yamazaki , Akihiro Tobe
IPC分类号： A61K31/50 , A61P1/00 , A61P1/08 , A61P25/04 , A61P25/20 , C07D403/12 , C07D451/04 , C07D451/06 , C07D453/02 , C07D471/08 , C07D487/08 , A61K31/55 , C07D237/28 , C07D401/12
CPC分类号： C07D451/04 , C07D451/06 , C07D453/02
摘要： A novel cinnoline derivative having an antagonistic activity against serotonin 5-HT.sub.3 receptor, its pharmaceutically acceptable salts, its N-oxide derivatives or solvates thereof, and pharmaceutical formulations containing the same for the prevention and/or treatment of various disorders such as nausea and/or emesis caused by anticancer drugs or X-ray treatment, central nervous disorders such as anxiety and/or neuropathy, gastroenteric diseases such as indigestion, chronic gastritis, digestive ulcer, irritable bowel syndromes and the like, hemicrania, cluster headache, trigeminal neuralgia, arrhythmia and the like.
摘要翻译：对5-羟色胺5-HT 3受体具有拮抗活性的新颖的噌啉衍生物，其药学上可接受的盐，其N-氧化物衍生物或溶剂合物，以及含有其的预防和/或治疗各种疾病如恶心和/ 或由抗癌药物或X线治疗引起的呕吐，焦虑和/或神经病变等中枢神经障碍，消化不良，慢性胃炎，消化性溃疡，肠易激综合征等胃肠疾病，血红素，丛集性头痛，三叉神经痛，心律失常等。

7. 发明授权

US09456980B2 Latanoprost-containing aqueous pharmaceutical composition 有权
标题翻译：含拉坦前列素的水性药物组合物
公开(公告)号：US09456980B2
公开(公告)日：2016-10-04
申请号：US12674962
申请日：2008-08-29
申请人： Kohei Yoda , Satoshi Yamazaki , Emi Kawaguchi
发明人： Kohei Yoda , Satoshi Yamazaki , Emi Kawaguchi
IPC分类号： A61K9/00 , A61K31/5575 , A61K31/215 , A61K31/557 , A61K47/14 , A61K47/26 , A61K47/44
CPC分类号： A61K9/0048 , A61K31/215 , A61K31/557 , A61K31/5575 , A61K47/14 , A61K47/26 , A61K47/44
摘要： The invention provides a latanoprost-containing aqueous pharmaceutical composition filled in a filter-equipped container, with the adsorption of latanoprost by the filter being prevented. In the latanoprost-containing aqueous pharmaceutical composition filled in the filter-equipped container, a nonionic surfactant is contained in the composition and the filter is made from at least one material selected from the group consisting of polyether sulfone, polyvinylidene fluoride, polycarbonate, and polytetrafluoroethylene.
摘要翻译：本发明提供一种填充在装有过滤器的容器中的含有拉坦前列素的水性药物组合物，其中通过过滤器吸收拉坦前列素。在装有过滤器的容器中的含有拉坦前列素的水性药物组合物中，组合物中含有非离子表面活性剂，过滤器由选自聚醚砜，聚偏二氟乙烯，聚碳酸酯，聚四氟乙烯。

8. 发明授权

US08749831B2 Printing system and data transfer method 有权
标题翻译：打印系统和数据传输方式
公开(公告)号：US08749831B2
公开(公告)日：2014-06-10
申请号：US13647808
申请日：2012-10-09
申请人： Satoshi Yamazaki , Shinichi Arazaki , Kohei Utsunomiya
发明人： Satoshi Yamazaki , Shinichi Arazaki , Kohei Utsunomiya
IPC分类号： G06F3/12
CPC分类号： H04N1/33323 , G06F3/1212 , G06F3/1236 , G06F3/1244 , G06F3/1285 , G06F3/1292 , H04N1/00233 , H04N1/33361 , H04N2201/0044 , H04N2201/0082 , H04N2201/33357 , H04N2201/33378
摘要： A printing system provided with a printer and a host computer which transfers image data to the printer includes a data transfer unit configured to transfer the image data as image data of a first data format in the case where a connection between the printer and the host computer is first connection means, and transfer the image data as image data of a second data format in the case where a connection between the printer and the host computer is second connection means, wherein the second connection means has less data communication amount per unit time than the first connection means, and when given image data is transferred, image data of the second data format, corresponding to the given image data, has less data amount than image data of the first data format, corresponding to the given image data.
摘要翻译：具有将图像数据传送到打印机的打印机和主计算机的打印系统包括数据传送单元，其被配置为在打印机和主计算机之间的连接的情况下将图像数据作为第一数据格式的图像数据传送是第一连接装置，并且在打印机和主机之间的连接是第二连接装置的情况下，将图像数据作为第二数据格式的图像数据传送，其中第二连接装置具有比每单位时间少的数据通信量第一连接装置，并且当传送给定图像数据时，对应于给定图像数据的第二数据格式的图像数据具有比对应于给定图像数据的第一数据格式的图像数据更少的数据量。

9. 发明授权

US08039423B2 Lubricant composition, speed reduction gear using the lubricant composition, and electric power steering apparatus using the speed reduction gear 有权
标题翻译：使用润滑剂组合物的润滑剂组合物，减速装置以及使用减速装置的电动助力转向装置
公开(公告)号：US08039423B2
公开(公告)日：2011-10-18
申请号：US10593820
申请日：2005-03-23
申请人： Kouji Kitahata , Fumiaki Kasahara , Yoshimasa Shirai , Takashi Okaniwa , Satoshi Yamazaki
发明人： Kouji Kitahata , Fumiaki Kasahara , Yoshimasa Shirai , Takashi Okaniwa , Satoshi Yamazaki
IPC分类号： C10M135/10 , C10M149/00
CPC分类号： C10M169/06 , C10M2201/05 , C10M2201/0626 , C10M2201/0876 , C10M2205/0206 , C10M2207/1265 , C10M2215/1026 , C10M2217/045 , C10M2219/0445 , C10M2219/0466 , C10N2220/022 , C10N2220/08 , C10N2220/082 , C10N2230/06 , C10N2230/76 , C10N2240/04 , C10N2250/10 , F16H1/16 , F16H57/0006 , F16H57/0498 , Y10T74/19991
摘要： Disclosed are a lubricant composition including a lubricating base oil, fine particles and a calcium sulfonate-based thickener, a speed reduction gear filled with the lubricant composition, and an electric power steering apparatus including the speed reduction gear. The invention reduces operating noise of the speed reduction gear, regardless of the amount of backlash that occurs on combining a small gear and a large gear and without a more complicated structure for the speed reduction gear, by action of the fine particles. Further, separation of oil is prevented, by action of the calcium sulfonate-based thickener of the lubricant composition, so that electric power steering apparatus noise within the inside of a car is reduced at a low cost.
摘要翻译：公开了一种润滑剂组合物，其包含润滑基础油，细颗粒和基于磺酸钙的增稠剂，填充有润滑剂组合物的减速齿轮以及包括减速齿轮的电动助力转向装置。无论细小颗粒的作用如何，通过组合小齿轮和大齿轮以及减速齿轮结构不复杂的结构，都能够减轻减速装置的运转噪音。此外，通过润滑剂组合物的磺酸钙系增稠剂的作用，可以防止油分离，从而以低成本降低了汽车内部的电动助力转向装置的噪音。

10. 发明授权

US07835085B2 Lens barrel and method of operation of lens barrel 有权
标题翻译：镜筒和镜筒操作方法
公开(公告)号：US07835085B2
公开(公告)日：2010-11-16
申请号：US11588275
申请日：2006-10-27
申请人： Satoshi Yamazaki
发明人： Satoshi Yamazaki
IPC分类号： G02B15/14
CPC分类号： G02B7/10 , G02B15/14
摘要： A lens barrel having a first moving barrel, second moving barrel, and a third moving barrel. The first moving barrel has first cam grooves configured corresponding to a focusing operation and holds an optical system used in a focusing operation. The second moving barrel has second cam grooves and is provided in relation to the first moving barrel. The third moving barrel has third cam grooves configured corresponding to a zoom operation and can move relative to a fixed barrel. The second cam grooves correct a position of said optical system corresponding to a drive operation of the third cam grooves.
摘要翻译：镜筒具有第一移动镜筒，第二移动镜筒和第三移动镜筒。第一移动筒具有对应于聚焦操作配置的第一凸轮槽，并且保持用于聚焦操作的光学系统。第二移动筒具有第二凸轮槽，并且相对于第一移动筒设置。第三移动筒具有对应于变焦操作构造的第三凸轮槽，并且可相对于固定筒移动。第二凸轮槽对应于第三凸轮槽的驱动操作校正所述光学系统的位置。

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