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    • 2. 发明申请
    • Methods for Treatment of Ophthalmic Disease of an External Ophthalmic Tissue
    • 治疗外眼科眼科疾病的方法
    • US20100150992A1
    • 2010-06-17
    • US12712459
    • 2010-02-25
    • Kohji KawaharaYasuhiko AramomiAkira OhtoriAkiharu Isowaki
    • Kohji KawaharaYasuhiko AramomiAkira OhtoriAkiharu Isowaki
    • A61K9/70A61P27/02A61K31/4535A61K31/196
    • A61K9/7053A61K9/0048A61K9/7076
    • A transdermal drug delivery system for treatment of ophthalmic diseases comprising a structure that a plaster layer containing a remedy for ophthalmic diseases is provided on a support, wherein the system is applied to a skin surface including a front surface of an eyelid to administer the remedy for ophthalmic diseases in the plaster layer to an ophthalmic topical tissue by percutaneous permeation substantially without being administered through a systemic blood flow. Use of the transdermal drug delivery system for treatment of ophthalmic diseases, comprising applying the transdermal drug delivery system to a skin surface including a front surface of an eyelid to transfer the remedy for ophthalmic diseases in the plaster layer to an ophthalmic topical tissue by percutaneous permeation substantially without being administered through a systemic blood flow, and a method for transferring the remedy for ophthalmic diseases to the ophthalmic topical tissue.
    • 一种用于治疗眼科疾病的透皮药物递送系统,包括在载体上设置含有用于眼科疾病补救剂的膏药层的结构,其中将该系统施用于包括眼睑前表面的皮肤表面, 石膏层中的眼科疾病通过经皮渗透到眼部局部组织,基本上不经由全身血流量施用。 使用透皮药物递送系统来治疗眼科疾病,包括将透皮药物递送系统施用于包括眼睑前表面的皮肤表面,以通过经皮渗透将膏药层中的眼科疾病的药物转移至眼用局部组织 基本上不经由全身血流量施用,以及用于将眼科疾病的药物转移到眼用局部组织的方法。
    • 3. 发明授权
    • Motion detection apparatus and motion detecting method
    • 运动检测装置和运动检测方法
    • US07813892B2
    • 2010-10-12
    • US11718340
    • 2005-11-01
    • Takashi SugawaraKohji KawaharaYuji Chotoku
    • Takashi SugawaraKohji KawaharaYuji Chotoku
    • G01C22/00
    • G08B13/1436G01H1/06G01H1/08G06F21/88
    • A motion detection apparatus includes an acceleration sensor which detects acceleration generated by motion of an electronic device; a motion detecting section including a statistical processing section which calculates the average value of data provided from the acceleration sensor, calculates the difference between the average value and the last value of the data obtained, and calculates a pseudo-variance value of the data from the calculated difference; a threshold comparing section which compares the pseudo-variance value calculated by the motion detecting section with a motion threshold to generate a signal value in response to determination that the pseudo-variance value has exceeded the motion threshold; a first buffer memory which sequentially stores signal values generated by the threshold comparing section at predetermined time intervals; and a signal generating section which includes means for adding up values in the first buffer memory, thereby appropriately associating with motion.
    • 运动检测装置包括加速度传感器,其检测由电子装置的运动产生的加速度; 运动检测部分,包括计算从加速度传感器提供的数据的平均值的统计处理部分,计算所获得的数据的平均值和最后值之间的差,并且计算来自所述加速度传感器的数据的伪方差值 计算差额 阈值比较部分,其将运动检测部分计算的伪方差值与运动阈值进行比较,以响应于伪方差值已经超过运动阈值的确定来生成信号值; 第一缓冲存储器,其以预定的时间间隔顺序地存储由阈值比较部分生成的信号值; 以及信号产生部分,其包括用于将第一缓冲存储器中的值相加的装置,从而适当地与运动相关联。
    • 5. 发明申请
    • Motion Detection Apparatus and Motion Detecting Method
    • 运动检测装置和运动检测方法
    • US20090006028A1
    • 2009-01-01
    • US11718340
    • 2005-11-01
    • Takashi SugawaraKohji KawaharaYuji Chotoku
    • Takashi SugawaraKohji KawaharaYuji Chotoku
    • G01P15/00
    • G08B13/1436G01H1/06G01H1/08G06F21/88
    • A motion detection apparatus includes an acceleration sensor which detects acceleration generated by motion of an electronic device; a motion detecting section including a statistical processing section which calculates the average value of data provided from the acceleration sensor, calculates the difference between the average value and the last value of the data obtained, and calculates a pseudo-variance value of the data from the calculated difference; a threshold comparing section which compares the pseudo-variance value calculated by the motion detecting section with a motion threshold to generate a signal value in response to determination that the pseudo-variance value has exceeded the motion threshold; a first buffer memory which sequentially stores signal values generated by the threshold comparing section at predetermined time intervals; and a signal generating section which includes means for adding up values in the first buffer memory, thereby appropriately associating acceleration with motion.
    • 运动检测装置包括加速度传感器,其检测由电子装置的运动产生的加速度; 运动检测部分,包括计算从加速度传感器提供的数据的平均值的统计处理部分,计算所获得的数据的平均值和最后值之间的差,并且计算来自所述加速度传感器的数据的伪方差值 计算差额 阈值比较部分,其将由运动检测部分计算的伪方差值与运动阈值进行比较,以响应于伪方差值已经超过运动阈值的确定而产生信号值; 第一缓冲存储器,其以预定的时间间隔顺序地存储由阈值比较部分生成的信号值; 以及信号产生部分,其包括用于将第一缓冲存储器中的值相加的装置,从而将加速度与运动适当地相关联。