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1. 发明授权

US07279465B2 Use of amphiphilic nucleoside phosphonoformic acid derivatives for the treatment of viral infectious diseases 失效
标题翻译：使用两亲核苷磷酰甲酸衍生物治疗病毒性传染病
公开(公告)号：US07279465B2
公开(公告)日：2007-10-09
申请号：US11015209
申请日：2004-12-16
申请人： Klaus Hamprecht , Gerhard Jahn , Herbert Schott
发明人： Klaus Hamprecht , Gerhard Jahn , Herbert Schott
IPC分类号： A01N43/04 , A61K31/70 , C07H19/00 , C07H21/00
CPC分类号： A61K31/7072 , A61K31/047
摘要： The invention relates to a method for treating infectious diseases which are elicited by viruses which are pathogenic to humans comprising the step of administering an amphiphilic nucleoside-phosphonoformic acid derivative having an esterified or unesterified carboxyl group, preferably of a nucleoside-glycerol-(hydroxycarbonyl)-phosphonate, as an active compound.
摘要翻译：本发明涉及一种治疗感染性疾病的方法，所述感染性疾病是由对人体致病的病毒引起的，包括施用具有酯化或未酯化羧基的两亲核苷 - 膦酰甲酸衍生物的步骤，优选核苷 - 甘油 - （羟基羰基）膦酸酯，作为活性化合物。

2. 发明申请

US20060172997A1 Combinations of inhibitors of reverse transcriptase and inhibitors of virus-encoded DNA polymerase 审中-公开
标题翻译：逆转录酶抑制剂与病毒编码DNA聚合酶抑制剂的组合
公开(公告)号：US20060172997A1
公开(公告)日：2006-08-03
申请号：US11265825
申请日：2005-11-03
申请人： Klaus Hamprecht , Herbert Schott , Elfriede Mikeler , Gerhard Jahn
发明人： Klaus Hamprecht , Herbert Schott , Elfriede Mikeler , Gerhard Jahn
IPC分类号： A61K31/551 , A61K31/522 , A61K31/513
CPC分类号： A61K45/06
摘要： A method for treating viral diseases which are caused by DNA viruses is described comprising administering an effective amount of at least one inhibitor of reverse transcriptase (RTI) in combination with at least one inhibitor of viral DNA polymerase, wherein the at least one RTI and the at least one DNA polymerase inhibitor are present in the form of separate compounds.
摘要翻译：描述了用于治疗由DNA病毒引起的病毒性疾病的方法，其包括将有效量的至少一种逆转录酶（RTI）抑制剂与至少一种病毒DNA聚合酶抑制剂组合施用，其中所述至少一种RTI和至少一种DNA聚合酶抑制剂以分开的化合物的形式存在。

3. 发明申请

US20050187183A1 Use of amphiphilic nucleoside phosphonoformic acid derivatives for the treatment of viral infectious diseases 失效
标题翻译：使用两亲核苷磷酰甲酸衍生物治疗病毒性传染病
公开(公告)号：US20050187183A1
公开(公告)日：2005-08-25
申请号：US11015209
申请日：2004-12-16
申请人： Klaus Hamprecht , Gerhard Jahn , Herbert Schott
发明人： Klaus Hamprecht , Gerhard Jahn , Herbert Schott
IPC分类号： A61K31/047 , A61K31/7072 , A61P31/12
CPC分类号： A61K31/7072 , A61K31/047
摘要： The invention relates to a method for treating infectious diseases which are elicited by viruses which are pathogenic to humans comprising the step of administering an amphiphilic nucleoside-phosphonoformic acid derivative having an esterified or unesterified carboxyl group, preferably of a nucleoside-glycerol-(hydroxycarbonyl)-phosphonate, as an active compound.
摘要翻译：本发明涉及一种治疗感染性疾病的方法，所述感染性疾病是由对人体致病的病毒引起的，包括施用具有酯化或未酯化羧基的两亲核苷 - 膦酰甲酸衍生物的步骤，优选核苷 - 甘油 - （羟基羰基）膦酸酯，作为活性化合物。

4. 发明申请

US20100294141A1 METHOD AND DEVICE FOR THE TREATMENT OF MILK, ESPECIALLY BREAST MILK 审中-公开
标题翻译：用于治疗奶酪，特别是乳制品的方法和装置
公开(公告)号：US20100294141A1
公开(公告)日：2010-11-25
申请号：US12833875
申请日：2010-07-09
申请人： Gerhard Jahn , Christian P. Speer , Jens Maschmann , Klaus Hamprecht , Klaus Lauf
发明人： Gerhard Jahn , Christian P. Speer , Jens Maschmann , Klaus Hamprecht , Klaus Lauf
IPC分类号： A23C3/02 , A23C3/04
CPC分类号： A23C3/03 , A23C9/206
摘要： A device for treating milk contained in a container is disclosed. The device comprises at least one heat source that comprises an air bath, a device for setting the container in motion and exposing the container to the heat source for a defined period of time, and a cooling source for cooling the milk.
摘要翻译：公开了一种用于处理容纳在容器中的牛奶的装置。该装置包括至少一个包括空气浴的热源，用于设置容器运动并将容器暴露于热源一定时间的装置，以及用于冷却牛奶的冷却源。

5. 发明申请

US20060159817A1 Method and device for the treatment of milk, especially breast milk 有权
标题翻译：用于治疗牛奶，特别是母乳的方法和装置
公开(公告)号：US20060159817A1
公开(公告)日：2006-07-20
申请号：US11303866
申请日：2005-12-16
申请人： Gerhard Jahn , Christian Speer , Jens Maschmann , Klaus Hamprecht , Klaus Lauf
发明人： Gerhard Jahn , Christian Speer , Jens Maschmann , Klaus Hamprecht , Klaus Lauf
IPC分类号： C12C7/28
CPC分类号： A23C3/03 , A23C9/206
摘要： A method for treating milk, wherein milk is short-term heated in a container. At least during the heating, the container is set in motion in such a way that a milk film forms on the inner wall of the container. A device for carrying out the method is likewise described (FIG. 1).
摘要翻译：一种用于处理牛奶的方法，其中在容器中短期加热牛奶。至少在加热期间，将容器设置成运动，使得在容器的内壁上形成乳胶膜。同样描述了用于执行该方法的装置（图1）。

6. 发明授权

US07754259B2 Method and device for the treatment of milk, especially breast milk 有权
标题翻译：用于治疗牛奶，特别是母乳的方法和装置
公开(公告)号：US07754259B2
公开(公告)日：2010-07-13
申请号：US11303866
申请日：2005-12-16
申请人： Gerhard Jahn , Christian P. Speer , Jens Maschmann , Klaus Hamprecht , Klaus Lauf
发明人： Gerhard Jahn , Christian P. Speer , Jens Maschmann , Klaus Hamprecht , Klaus Lauf
IPC分类号： A23C3/03
CPC分类号： A23C3/03 , A23C9/206
摘要： A method for treating milk, wherein milk is short-term heated in a container. At least during the heating, the container is set in motion in such a way that a milk film forms on the inner wall of the container. A device for carrying out the method is likewise described (FIG. 1).
摘要翻译：一种用于处理牛奶的方法，其中在容器中短期加热牛奶。至少在加热期间，将容器设置成运动，使得在容器的内壁上形成乳胶膜。同样描述了用于执行该方法的装置（图1）。

7. 发明授权

US4129914A Automatic loading tray 失效
标题翻译：自动装载托盘
公开(公告)号：US4129914A
公开(公告)日：1978-12-19
申请号：US748928
申请日：1976-12-09
申请人： Gerhard Jahn
发明人： Gerhard Jahn
IPC分类号： B42C7/00 , B42C15/00
CPC分类号： B42C7/00 , Y10T29/53974
摘要： An improved automatic loading tray comprising a frame having lateral side rails and a pair of longitudinal cross-bar arrangements spaced from each other and secured to the lateral side rails for reciprocal movement therealong, each cross-bar arrangement including two laterally spaced substantially parallel bars, an inner and outer bar, said inner bar nearer said other cross-bar arrangement than said outer bar, and means to limit maximum separation between said two spaced bars, rotatable spacer means for positioning between said spaced bars, said rotatable means being of substantially uniform non-circular or non-square cross-section looking downwardly thereon for causing the bars to abut said means to limit their maximum separation when said rotatable means is positioned between said bars in a first position and for causing said bar to loosely seat between said means to limit maximum separation when said rotatable means is in a second position, and means to rotate said rotatable spacer means.
摘要翻译：一种改进的自动装载托盘，其包括具有侧向侧轨道的框架和彼此隔开并且固定到横向侧轨道的一对纵向横杆装置，用于在其上往复运动，每个横杆装置包括两个横向间隔开的大致平行的杆，内杆和外杆，所述内杆比所述外杆更靠近所述另一横杆布置，以及用于限制所述两个间隔杆之间的最大间隔的装置，用于定位在所述间隔杆之间的可旋转间隔装置，所述可旋转装置基本均匀非圆形或非正方形的横截面向下看，当所述可旋转装置位于所述杆之间处于第一位置时，使所述杆邻接所述装置以限制其最大间隔，并且使所述杆松动地位于所述装置以限制当所述可旋转装置处于第二位置时的最大间隔，以及用于旋转所述可旋转间隔件的装置手段。

8. 发明授权

US5849522A Enhancer for eukaryotic expression systems 失效
标题翻译：增强子用于真核表达系统
公开(公告)号：US5849522A
公开(公告)日：1998-12-15
申请号：US467143
申请日：1995-06-06
申请人： Bernhard Fleckenstein , Walter Schaffner , Frank Weber , Karoline Dorsch-Hasler , Gerhard Jahn , Michael Boshart
发明人： Bernhard Fleckenstein , Walter Schaffner , Frank Weber , Karoline Dorsch-Hasler , Gerhard Jahn , Michael Boshart
IPC分类号： C12N15/09 , C12N15/00 , C12N15/85 , C12P21/02 , C07H21/04 , C12N15/11 , C12N15/67
CPC分类号： C12N15/85 , C12N2800/60
摘要： An enhancer has been located in the upstream region of the major immediate early gene of human cytomegalovirus and has been isolated, which enhancer is more active than that from SV40 and has a wide host cell spectrum. Hence, it is suitable for eukaryotic expression systems wherein it can be incorporated upstream or downstream of the structural gene or of the regulation region.
摘要翻译：增强子已经位于人巨细胞病毒的主要即时早期基因的上游区域，并且已被分离，其增强剂比来自SV40的活性更强，并且具有广泛的宿主细胞谱。因此，它适合于其可以结合到结构基因或调节区的上游或下游的真核表达系统。

9. 发明授权

US5656475A Use of lymphocytes transformed with herpesvirus saimiri in a process for replicating viruses of the HIV type which cause immune deficiency 失效
标题翻译：使用疱疹病毒simiri转化的淋巴细胞在复制HIV型病毒的过程中引起免疫缺陷
公开(公告)号：US5656475A
公开(公告)日：1997-08-12
申请号：US208299
申请日：1994-03-10
申请人： Sigrid Nick , Helmut Fickenscher , Brigitte Biesinger-Zwosta , Gerhard Jahn , Bernhard Fleckenstein
发明人： Sigrid Nick , Helmut Fickenscher , Brigitte Biesinger-Zwosta , Gerhard Jahn , Bernhard Fleckenstein
IPC分类号： C12N5/10 , C12N7/00 , C12N7/02 , C12N15/09 , C12R1/91 , C12R1/92 , C12Q1/70
CPC分类号： C12N7/00 , C12N2710/16611
摘要： A process is disclosed for replicating viruses of the HIV type which cause immune deficiency, in which process lymphocytes are employed which have been transformed with herpesvirus saimiri.
摘要翻译：公开了一种用于复制引起免疫缺陷的HIV型病毒的方法，其中使用已经用疱疹病毒saimiri转化的淋巴细胞。

10. 发明授权

US4192620A Loose leaf binder 失效
标题翻译：松散的叶片粘合剂
公开(公告)号：US4192620A
公开(公告)日：1980-03-11
申请号：US4811
申请日：1979-01-19
申请人： Gerhard Jahn
发明人： Gerhard Jahn
IPC分类号： B42C7/00 , B42F13/10 , B42F3/04
CPC分类号： B42C7/002 , B42F13/10
摘要： An improved binder, of one step construction manufactured from a single sheet of material comprising front and back covers, a backing disposed therebetween joining the covers and forming a continuation of the plane of the adjacent covers a plurality of fastening means, each fastening means formed integrally from one portion of one of said covers and forming a continuation of the plane of said cover at the juncture of the fastening means and the cover thereby presenting a cut-out portion in the cover corresponding to the shape of the fastening means when a part of the fastening means is lifted from the plane of the binder cover, each of said fastening means comprising a strap and tab, the strap forming a continuation of the plane of the cover at one end, the tab being disposed at the other end of the strap and forming a continuation of the plane thereof and of a width at the juncture with the strap to define therewith at least one locking shoulder, a plurality of slots disposed in said binder, one slot for each fastening means, through which slot each fastening means is inserted for positioning exterior of the binder cover, for insertion through the cut-out portion in the cover to be positioned within the interior of the binder and be locked and secured therein by at least one locking shoulder of said tab engaging cover portions on either side of the cut-away portion.
摘要翻译：一种改进的粘合剂，由包括前盖和后盖的单片材料制成的一步构造，其间设置在其间的背衬，其接合所述盖并且形成相邻盖的平面的延续部，多个紧固装置，每个紧固装置一体地形成从所述盖中的一个的一部分形成所述盖的平面在所述紧固装置和所述盖的接合处的延续部，从而在所述盖的对应于所述紧固装置的形状的一部分上形成切口部分所述紧固装置从所述装订机盖的平面提升，每个所述紧固装置包括带和突片，所述带在一端形成所述盖的平面的延续，所述突片设置在所述带的另一端并且形成其平面的延续并且在与该带的接合部处具有宽度以限定其至少一个锁定肩部，多个狭槽设置在所述粘合剂，每个紧固装置的一个槽，每个紧固装置通过该槽插入用于定位活页夹盖的外部，用于插入通过盖中的切口部分以定位在粘合剂的内部并被锁定和固定其中所述突片的至少一个锁定肩部接合在切除部分的任一侧的盖部分。

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