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1. 发明申请

US20050277205A1 Multicomponent magnetic nanorods for biomolecular separations 审中-公开
标题翻译：用于生物分子分离的多组分磁性纳米棒
公开(公告)号：US20050277205A1
公开(公告)日：2005-12-15
申请号：US11062983
申请日：2005-02-22
申请人： Ki-Bum Lee , Sungho Park , Chad Mirkin , Byung-Keun Oh
发明人： Ki-Bum Lee , Sungho Park , Chad Mirkin , Byung-Keun Oh
IPC分类号： C12Q1/68 , G01N33/531 , G01N33/553
CPC分类号： G01N33/531 , B82Y5/00
摘要： The present invention relates to methods and compositions for separation of proteins. In particular, the present invention provides multicomponent nanorods for biomolecular separations of proteins.
摘要翻译：本发明涉及分离蛋白质的方法和组合物。特别地，本发明提供了用于蛋白质的生物分子分离的多组分纳米棒。

2. 发明申请

US20060040286A1 Bio-barcode based detection of target analytes 审中-公开
标题翻译：基于生物条形码的目标分析物检测
公开(公告)号：US20060040286A1
公开(公告)日：2006-02-23
申请号：US11127808
申请日：2005-05-12
申请人： Chad Mirkin , Jwa-Min Nam , Byung-Keun Oh , C. Shad Thaxton , Dimitra Georganopoulou
发明人： Chad Mirkin , Jwa-Min Nam , Byung-Keun Oh , C. Shad Thaxton , Dimitra Georganopoulou
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6816 , G01N33/54333 , C12Q2565/501 , C12Q2565/113 , C12Q2563/179 , C12Q2563/143 , C12Q2563/149 , C12Q2563/155
摘要： The present invention relates to screening methods, compositions, and kits for detecting for the presence or absence of one or more target analytes, e.g. biomolecules, in a sample. In particular, the present invention relates to a method that utilizes reporter oligonucleotides as biochemical barcodes for detecting multiple protein structures or other target analytes in a solution.
摘要翻译：本发明涉及用于检测一种或多种目标分析物的存在或不存在的筛选方法，组合物和试剂盒，例如，生物分子。特别地，本发明涉及利用报告寡核苷酸作为检测多种蛋白质结构或溶液中其它目标分析物的生化条形码的方法。

3. 发明申请

US20100270543A1 Biomolecule-Based Electronic Device 有权
标题翻译：基于生物分子的电子设备
公开(公告)号：US20100270543A1
公开(公告)日：2010-10-28
申请号：US12809646
申请日：2008-04-17
申请人： Jeong-Woo Choi , Jun-Hong Min , Byung-Keun Oh , Hyun-Hee Kim , Young-Jun Kim
发明人： Jeong-Woo Choi , Jun-Hong Min , Byung-Keun Oh , Hyun-Hee Kim , Young-Jun Kim
IPC分类号： H01L51/30
CPC分类号： G11C13/0014 , B82Y10/00 , G11C13/0009 , G11C13/0019 , H01L51/0093 , H01L51/0591
摘要： The present invention relates to a biomolecule-based electronic device in which the biomolecule with redox potential is directly immobilized on the substrate. The present invention enables to excellently exhibit the capability of a protein-based bio-memory device in which it is preferable to use the substrate on which cysteine-introduced recombinant proteins are effectively immobilized and a self-assembled layer (SAM) is fabricated. It becomes realized that a redox potential is regulated using intrinsic redox potential of the protein dependent on applied voltage. The present invention provides a novel operating method in which three potentials are applied throughout four steps. The present invention has some advantages of fabricating a protein layer in a convenient manner and inducing electron transfer by fundamental electrochemical or electronic operation. The method of this invention is considered as a new concept in the senses that intrinsic electron transfer mechanisms induced by natural-occurring biomolecules are used to develop an information storage device.
摘要翻译：本发明涉及一种基于生物分子的电子器件，其中具有氧化还原电位的生物分子直接固定在基底上。本发明能够优异地表现出蛋白质生物记忆装置的能力，其中优选使用其上有效固定半胱氨酸导入的重组蛋白质的底物和制造自组装层（SAM）。实现使用依赖于施加电压的蛋白质的固有氧化还原电位来调节氧化还原电位。本发明提供一种新的操作方法，其中三个电位通过四个步骤施加。本发明具有以方便的方式制造蛋白质层并通过基本电化学或电子操作诱导电子转移的一些优点。本发明的方法被认为是用天然存在的生物分子诱导的固有电子传递机制来开发信息存储装置的感觉的新概念。

4. 发明授权

US08692233B2 Biomolecule-based electronic device 有权
标题翻译：基于生物分子的电子设备
公开(公告)号：US08692233B2
公开(公告)日：2014-04-08
申请号：US12809646
申请日：2008-04-17
申请人： Jeong-Woo Choi , Jun-Hong Min , Byung-Keun Oh , Hyun-Hee Kim , Young-Jun Kim
发明人： Jeong-Woo Choi , Jun-Hong Min , Byung-Keun Oh , Hyun-Hee Kim , Young-Jun Kim
IPC分类号： H01L29/08 , H01L35/24 , H01L51/00
CPC分类号： G11C13/0014 , B82Y10/00 , G11C13/0009 , G11C13/0019 , H01L51/0093 , H01L51/0591
摘要： The present invention relates to a biomolecule-based electronic device in which the biomolecule with redox potential is directly immobilized on the substrate. The present invention enables to excellently exhibit the capability of a protein-based bio-memory device in which it is preferable to use the substrate on which cysteine-introduced recombinant proteins are effectively immobilized and a self-assembled layer (SAM) is fabricated. It becomes realized that a redox potential is regulated using intrinsic redox potential of the protein dependent on applied voltage. The present invention provides a novel operating method in which three potentials are applied throughout four steps. The present invention has some advantages of fabricating a protein layer in a convenient manner and inducing electron transfer by fundamental electrochemical or electronic operation. The method of this invention is considered as a new concept in the senses that intrinsic electron transfer mechanisms induced by natural-occurring biomolecules are used to develop an information storage device.
摘要翻译：本发明涉及一种基于生物分子的电子器件，其中具有氧化还原电位的生物分子直接固定在基底上。本发明能够优异地表现出蛋白质生物记忆装置的能力，其中优选使用其上有效固定半胱氨酸导入的重组蛋白质的底物和制造自组装层（SAM）。实现使用依赖于施加电压的蛋白质的固有氧化还原电位来调节氧化还原电位。本发明提供一种新的操作方法，其中三个电位通过四个步骤施加。本发明具有以方便的方式制造蛋白质层并通过基本电化学或电子操作诱导电子转移的一些优点。本发明的方法被认为是用天然存在的生物分子诱导的固有电子传递机制来开发信息存储装置的感觉的新概念。

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