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1. 发明授权

US07821264B2 System and method for MR imaging in inhomogeneous magnetic fields 有权
标题翻译：非均匀磁场中MR成像的系统和方法
公开(公告)号：US07821264B2
公开(公告)日：2010-10-26
申请号：US12016331
申请日：2008-01-18
申请人： Kevin M. Koch , Kevin F. King , Reed F. Busse
发明人： Kevin M. Koch , Kevin F. King , Reed F. Busse
IPC分类号： G01V3/00
CPC分类号： G01R33/243 , G01R33/4822 , G01R33/5608 , G01R33/56563
摘要： An apparatus and method for MR imaging in inhomogeneous magnetic fields includes acquisition of a plurality of three-dimensional (3D) MR data sets, each data set having a central transmit frequency and a central receive frequency set to a frequency offset that is distinct for each 3D MR data set. A composite image is generated based on the plurality of 3D MR data sets.
摘要翻译：用于不均匀磁场中的MR成像的装置和方法包括获取多个三维（MR）MR数据集，每个数据集具有中心发射频率和中心接收频率，该频率偏移设定为每个 3D MR数据集。基于多个3D MR数据集生成合成图像。

2. 发明申请

US20090184711A1 SYSTEM AND METHOD FOR MR IMAGING IN INHOMOGENEOUS MAGNETIC FIELDS 有权
标题翻译：非均匀磁场中MR成像的系统和方法
公开(公告)号：US20090184711A1
公开(公告)日：2009-07-23
申请号：US12016331
申请日：2008-01-18
申请人： Kevin M, Koch , Kevin F. King , Reed F. Busse
发明人： Kevin M, Koch , Kevin F. King , Reed F. Busse
IPC分类号： G01R33/54
CPC分类号： G01R33/243 , G01R33/4822 , G01R33/5608 , G01R33/56563
摘要： An apparatus and method for MR imaging in inhomogeneous magnetic fields includes acquisition of a plurality of three-dimensional (3D) MR data sets, each data set having a central transmit frequency and a central receive frequency set to a frequency offset that is distinct for each 3D MR data set. A composite image is generated based on the plurality of 3D MR data sets.
摘要翻译：用于不均匀磁场中的MR成像的装置和方法包括获取多个三维（MR）MR数据集，每个数据集具有中心发射频率和中心接收频率，该频率偏移设定为每个 3D MR数据集。基于多个3D MR数据集生成合成图像。

3. 发明授权

US08228060B2 Method and apparatus for generating a flip angle schedule for a spin echo train pulse sequence 有权
标题翻译：用于产生自旋回波串脉冲序列的翻转调度表的方法和装置
公开(公告)号：US08228060B2
公开(公告)日：2012-07-24
申请号：US11767903
申请日：2007-06-25
申请人： Reed F. Busse
发明人： Reed F. Busse
IPC分类号： G01V3/00
CPC分类号： A61B5/055 , G01R33/5615 , G01R33/5617 , G01R33/5618
摘要： A method for calculating a flip angle schedule for a train of refocusing radio frequency (RF) pulses with reduced flip angles allows control of RF power deposition and use of a longer echo train. A target signal is defined for each echo in the echo train, and flip angles are then calculated from the target signals. The target signal schedule includes two phases. In the first phase, the target signals drop asymptotically to efficiently establish a pseudo-steady state at a pre-defined minimum signal level, Smin. In the second phase, the target signal is increased monotonically for the remainder of the train to a pre-defined maximum signal level, Smax. By increasing the target signal, the effect of relaxation may be reduced, decreasing blurring and ringing artifacts. Flip angles are then calculated from the target signal schedule, using a simplified method that requires no information about the tissues' relaxation properties.
摘要翻译：用于计算具有减小的翻转角度的重新聚焦射频（RF）脉冲串的翻转角度调度的方法允许控制RF功率沉积和使用更长的回波串。对于回波列中的每个回波定义目标信号，然后从目标信号计算翻转角。目标信号调度包括两个阶段。在第一阶段，目标信号渐近地下降以在预定义的最小信号电平Smin下有效地建立伪稳态。在第二阶段，对于列车的其余部分，目标信号单调增加到预定义的最大信号电平Smax。通过增加目标信号，可以减轻松弛的影响，减少模糊和振铃伪像。然后使用不需要有关组织松弛性质的信息的简化方法，从目标信号调度计算翻转角度。

4. 发明申请

US20080319301A1 METHOD AND APPARATUS FOR GENERATING A FLIP ANGLE SCHEDULE FOR A SPIN ECHO TRAIN PULSE SEQUENCE 有权
标题翻译：用于产生旋转ECHO脉冲序列的翻转角度表的方法和装置
公开(公告)号：US20080319301A1
公开(公告)日：2008-12-25
申请号：US11767903
申请日：2007-06-25
申请人： Reed F. Busse
发明人： Reed F. Busse
IPC分类号： A61B5/055
CPC分类号： A61B5/055 , G01R33/5615 , G01R33/5617 , G01R33/5618
摘要： A method for calculating a flip angle schedule for a train of refocusing radio frequency (RF) pulses with reduced flip angles allows control of RF power deposition and use of a longer echo train. A target signal is defined for each echo in the echo train, and flip angles are then calculated from the target signals. The target signal schedule includes two phases. In the first phase, the target signals drop asymptotically to efficiently establish a pseudo-steady state at a pre-defined minimum signal level, Smin. In the second phase, the target signal is increased monotonically for the remainder of the train to a pre-defined maximum signal level, Smax. By increasing the target signal, the effect of relaxation may be reduced, decreasing blurring and ringing artifacts. Flip angles are then calculated from the target signal schedule, using a simplified method that requires no information about the tissues' relaxation properties.
摘要翻译：用于计算具有减小的翻转角度的一系列重新聚焦射频（RF）脉冲的翻转角度计划的方法允许控制RF功率沉积和使用更长的回波串。对于回波列中的每个回波定义目标信号，然后从目标信号计算翻转角。目标信号调度包括两个阶段。在第一阶段，目标信号渐近地下降以在预定义的最小信号电平Smin下有效地建立伪稳态。在第二阶段，对于列车的其余部分，目标信号单调增加到预定义的最大信号电平Smax。通过增加目标信号，可以减轻松弛的影响，减少模糊和振铃伪像。然后使用不需要有关组织松弛性质的信息的简化方法，从目标信号调度计算翻转角度。

5. 发明授权

US06956374B2 Method and apparatus to reduce RF power in high field MR imaging incorporating multi-phase RF pulse flip angles 有权
公开(公告)号：US06956374B2
公开(公告)日：2005-10-18
申请号：US10612596
申请日：2003-07-02
申请人： Reed F. Busse
发明人： Reed F. Busse
IPC分类号： G01R33/48 , A61B5/055 , G01R33/561 , G01V3/00
CPC分类号： G01R33/5613
摘要： A technique is set forth that is designed to reduce RF induced power in high field MR imaging that includes application of an initial contrast preserving phase of RF pulses. These initial RF pulses are designed to have a constant, relatively high flip angle over the initial contrast preserving phase. Following an effective TE, a ramp down phase is applied that has a limited number of RF pulses with a flip angle that is less than the flip angle of those in the initial contrast preserving phase. Further, the RF pulses in the ramp down phase have a flip angle that is decreased over the ramp down phase. This technique provides improved resolution and steady contrast and SNR, while significantly reducing induced RF power.

6. 发明授权

US08120360B2 System and method of angular elliptic centric view ordering for 3D MR acquisitions 有权
标题翻译：用于3D MR采集的角椭圆中心视图排序的系统和方法
公开(公告)号：US08120360B2
公开(公告)日：2012-02-21
申请号：US12568355
申请日：2009-09-28
申请人： Manojkumar Saranathan , Ersin Bayram , Dan W. Rettmann , Reed F. Busse
发明人： Manojkumar Saranathan , Ersin Bayram , Dan W. Rettmann , Reed F. Busse
IPC分类号： G01V3/00
CPC分类号： G01R33/56518 , G01R33/4818 , G01R33/4822 , G01R33/4824
摘要： A method of magnetic resonance (MR) imaging includes segmenting a ky-kz plane comprising a plurality of encoding points into a plurality of annular segments. For each annular segment, a view ordering is defined based on a polar angle associated with each encoding point contained within the annular segment. MR data is acquired for the plurality of encoding points based on the view ordering for each annular segment and at least one MR image is generated using the acquired MR data.
摘要翻译：磁共振（MR）成像方法包括将包含多个编码点的ky-kz平面分割成多个环形段。对于每个环形段，视图排序基于与包含在环形段内的每个编码点相关联的极角来定义。基于每个环形段的视图顺序为多个编码点获取MR数据，并且使用获取的MR数据生成至少一个MR图像。

7. 发明授权

US06462545B1 Preparation sequence for gradient echo MRI acquisition 有权
标题翻译：梯度回波MRI采集准备顺序
公开(公告)号：US06462545B1
公开(公告)日：2002-10-08
申请号：US09717179
申请日：2000-11-20
申请人： Reed F. Busse , Stephen J. Riederer
发明人： Reed F. Busse , Stephen J. Riederer
IPC分类号： G01V300
CPC分类号： G01R33/5613
摘要： An image acquisition using a spoiled, gradient-recalled echo imaging pulse sequence is preceded by a magnetization preparation sequence which rapidly drives longitudinal magnetization to the steady-state equilibrium level established by the imaging pulse sequence. The preparation sequence includes an RF saturation pulse followed by a recovery period (Trec) whose length is determined by the scan parameters of the imaging pulse sequence.
摘要翻译：使用损坏的梯度回波成像脉冲序列的图像采集之前是磁化准备序列，其快速地将纵向磁化驱动到由成像脉冲序列建立的稳态平衡电平。制备序列包括RF饱和脉冲，随后是恢复期（Trec），其长度由成像脉冲序列的扫描参数确定。

8. 发明授权

US08760161B2 System and method for enhanced contrast MR imaging 有权
标题翻译：用于增强对比度MR成像的系统和方法
公开(公告)号：US08760161B2
公开(公告)日：2014-06-24
申请号：US13031354
申请日：2011-02-21
申请人： Raman Krishnan Subramanian , Reed F. Busse
发明人： Raman Krishnan Subramanian , Reed F. Busse
IPC分类号： G01V3/00
CPC分类号： G01R33/5617 , G01R33/5635
摘要： A system and method for enhanced contrast MR imaging include a computer programmed to perform a first scan of an imaging object based on a first fast spin echo (FSE) scan sequence comprising a first series of RF pulses having a first flip angle sequence to acquire a first MR data set and perform a second scan of the imaging object based on a second FSE scan sequence comprising a second series of RF pulses having a second flip angle sequence, wherein the second flip angle sequence is different from the first flip angle sequence to acquire a second MR data set. The computer is further programmed to generate a difference image based on the first and second MR data sets.
摘要翻译：用于增强对比度MR成像的系统和方法包括被编程为基于包括具有第一翻转角序列的第一系列RF脉冲的第一快速自旋回波（FSE）扫描序列执行成像对象的第一扫描的计算机，以获取第一MR数据集，并且基于包括具有第二翻转角序列的第二系列RF脉冲的第二FSE扫描序列执行成像对象的第二扫描，其中所述第二翻转角序列与所述第一翻转角序列不同以获取第二MR数据集。计算机还被编程为基于第一和第二MR数据集产生差分图像。

9. 发明授权

US07649354B2 Method and apparatus for acquiring magnetic resonance imaging data 有权
标题翻译：用于获取磁共振成像数据的方法和装置
公开(公告)号：US07649354B2
公开(公告)日：2010-01-19
申请号：US11861916
申请日：2007-09-26
申请人： Ersin Bayram , Charles R. Michelich , Anthony T. Vu , Reed F. Busse
发明人： Ersin Bayram , Charles R. Michelich , Anthony T. Vu , Reed F. Busse
IPC分类号： G01V3/00
CPC分类号： G01R33/561 , A61B5/7285 , G01R33/4818 , G01R33/4824 , G01R33/5611
摘要： A multi-shot three-dimensional (3D) magnetic resonance imaging (MRI) data view-ordering strategy for uniform or variable density k-space sampling schemes is presented. The ky-kz plane is partitioned into multiple wedge-shaped “blades” (or radial fan beams). The angular size of individual blades may be adjusted according to the desired number of views for each blade. Each blade includes views near the origin that contain low-frequency information about the imaged object such that views having the most desirable characteristics may be used to fill the central portions of k-space.
摘要翻译：提出了用于均匀或可变密度k空间采样方案的多次立体（3D）磁共振成像（MRI）数据视图排序策略。 ky-kz平面分为多个楔形“叶片”（或径向扇形横梁）。单个叶片的角度尺寸可以根据每个叶片的期望数量来调节。每个刀片包括原点附近的包含关于成像对象的低频信息的视图，使得具有最理想特性的视图可以用于填充k空间的中心部分。

10. 发明申请

US20090082656A1 METHOD AND APPARATUS FOR ACQUIRING MAGNETIC RESONANCE IMAGING DATA 有权
标题翻译：用于获取磁共振成像数据的方法和装置
公开(公告)号：US20090082656A1
公开(公告)日：2009-03-26
申请号：US11861916
申请日：2007-09-26
申请人： Ersin Bayram , Charles R. Michelich , Anthony T. Vu , Reed F. Busse
发明人： Ersin Bayram , Charles R. Michelich , Anthony T. Vu , Reed F. Busse
IPC分类号： A61B5/055 , G01R33/20
CPC分类号： G01R33/561 , A61B5/7285 , G01R33/4818 , G01R33/4824 , G01R33/5611
摘要： A multi-shot three-dimensional (3D) magnetic resonance imaging (MRI) data view-ordering strategy for uniform or variable density k-space sampling schemes is presented. The ky-kz plane is partitioned into multiple wedge-shaped “blades” (or radial fan beams). The angular size of individual blades may be adjusted according to the desired number of views for each blade. Each blade includes views near the origin that contain low-frequency information about the imaged object such that views having the most desirable characteristics may be used to fill the central portions of k-space.
摘要翻译：提出了用于均匀或可变密度k空间采样方案的多次立体（3D）磁共振成像（MRI）数据视图排序策略。 ky-kz平面分为多个楔形“叶片”（或径向扇形横梁）。单个叶片的角度尺寸可以根据每个叶片的期望数量来调节。每个刀片包括原点附近的包含关于成像对象的低频信息的视图，使得具有最理想特性的视图可以用于填充k空间的中心部分。

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