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1. 发明申请

US20070224615A1 METHODS FOR ASSAYING PROTEIN-PROTEIN INTERACTIONS 审中-公开
标题翻译：测定蛋白质 - 蛋白质相互作用的方法
公开(公告)号：US20070224615A1
公开(公告)日：2007-09-27
申请号：US11687549
申请日：2007-03-16
申请人： Kevin Lee , Brian Pollok , Zhong Zhong
发明人： Kevin Lee , Brian Pollok , Zhong Zhong
IPC分类号： C12Q1/68 , C12Q1/37
CPC分类号： C12Q1/6897
摘要： The invention relates, in part, to methods for detecting, monitoring, measuring or assessing an interaction between at least two proteins. The invention also relates, in part, to methods for determining if a test compound, or a mix of compounds, modulates an interaction between at least two proteins. In some embodiments, determination is made possible via the use of two recombinant molecules, e.g., one of which contains a first protein cleavage site for a proteolytic molecules, and an activator of a gene. A second recombinant molecule may include a second protein and the proteolytic molecule. Various other formats are provided by the invention. In some embodiments, if the test compound binds to the first protein, a reaction is initiated whereby the activator is cleaved, and activates a reporter gene.
摘要翻译：本发明部分地涉及用于检测，监测，测量或评估至少两种蛋白质之间相互作用的方法。本发明还部分涉及用于确定测试化合物或化合物混合物是否调节至少两种蛋白质之间的相互作用的方法。在一些实施方案中，通过使用两个重组分子（例如其中一个含有蛋白水解分子的第一蛋白切割位点）和基因的活化剂来进行测定。第二重组分子可以包括第二蛋白质和蛋白水解分子。本发明提供了各种其他格式。在一些实施方案中，如果测试化合物与第一种蛋白质结合，则开始反应，由此激活剂被切割，并激活报告基因。

2. 发明授权

US09984164B2 Search systems and methods with integration of aggregate user annotations 有权
公开(公告)号：US09984164B2
公开(公告)日：2018-05-29
申请号：US13192805
申请日：2011-07-28
申请人： Eckart Walther , Qi Lu , David Ku , Kevin Lee , Chung-Man Tam , Ali Diab
发明人： Eckart Walther , Qi Lu , David Ku , Kevin Lee , Chung-Man Tam , Ali Diab
IPC分类号： G06F17/30
CPC分类号： G06F17/30867 , G06F17/30696 , G06F17/30864 , G06F17/30882 , G06F17/30935 , Y10S707/99942 , Y10S707/99943 , Y10S707/99944 , Y10S707/99945
摘要： Computer systems and methods allow users to annotate content items found in a corpus such as the World Wide Web Annotations, which can include any descriptive and/or evaluative metadata related to a document, are collected from a user and stored in association with that user. Users are able to annotate and view their annotations for any document they encounter while interacting with the corpus, including hits returned in a search of the corpus. Users are also able to search their annotations or to limit searches to documents they have annotated. Metadata from annotations can also be aggregated across users and aggregated metadata applied in generating search results.

3. 发明申请

US20160324222A1 Adhesive Bra Construction For Deep Plunge Apparel 有权
标题翻译：深层服装胶粘胸罩
公开(公告)号：US20160324222A1
公开(公告)日：2016-11-10
申请号：US15065544
申请日：2016-03-09
申请人： Beverly Ann Deal , Rebecca Harmon , Kevin Lee
发明人： Beverly Ann Deal , Rebecca Harmon , Kevin Lee
IPC分类号： A41C3/06 , A41C5/00 , A41C3/00
CPC分类号： A41C3/065 , A41C3/0007 , A41C5/005
摘要： A bra comprised of separate left and right breast support members where each breast support member comprises a section of flexible sheet material formed to define a concave cavity and having tabs projecting radially outwardly from the cavity rim. Each breast support member defines a rear facing surface encompassing the cavity and tabs, which carries a pressure sensitive adhesive for adhering to a user's skin. The concave cavity constitutes a cup for accommodating the user's breast while the tabs enable the user to readily manipulate the support member for optimally positioning the user's breast relative to the cut of a deep plunge garment.
摘要翻译：一种由单独的左和右乳房支撑构件组成的胸罩，其中每个乳房支撑构件包括形成为限定凹腔的柔性片材的一部分，并且具有从腔缘径向向外突出的突出部。每个乳房支撑构件限定包围空腔和突出部的后向表面，该表面携带用于粘附到使用者皮肤的压敏粘合剂。凹腔构成用于容纳使用者的乳房的杯子，而翼片使得使用者能够容易地操纵支撑构件，以便相对于深穿衣服的切口最佳地定位使用者的乳房。

4. 发明授权

US09489463B2 Search systems and methods with integration of user annotations 有权
标题翻译：搜索系统和方法与用户注释集成
公开(公告)号：US09489463B2
公开(公告)日：2016-11-08
申请号：US13104569
申请日：2011-05-10
申请人： Eckart Walther , Qi Lu , David Ku , Kevin Lee , Chung-Man Tam , Ali Diab
发明人： Eckart Walther , Qi Lu , David Ku , Kevin Lee , Chung-Man Tam , Ali Diab
IPC分类号： G06F17/30
CPC分类号： G06F17/30867 , G06F17/30696 , G06F17/30864 , G06F17/30882 , G06F17/30935 , Y10S707/99942 , Y10S707/99943 , Y10S707/99944 , Y10S707/99945
摘要： Computer systems and methods allow users to annotate content items found in a corpus such as the World Wide Web. Annotations, which can include any descriptive and/or evaluative metadata related to a document, are collected from a user and stored in association with that user. Users are able to annotate and view their annotations for any document they encounter while interacting with the corpus, including hits returned in a search of the corpus. Users are also able to search their annotations or to limit searches to documents they have annotated. Metadata from annotations can also be aggregated across users and aggregated metadata applied in generating search results.
摘要翻译：计算机系统和方法允许用户注释在诸如万维网的语料库中发现的内容项。可以包括与文档相关的任何描述性和/或评估性元数据的注释，从用户收集并与该用户相关联地存储。用户可以在与语料库进行交互的同时，为他们遇到的任何文档注释并查看其注释，包括在语料库搜索中返回的命中。用户还可以搜索其注释或将搜索限制为已注释的文档。来自注释的元数据也可以跨用户聚合，并在生成搜索结果时应用汇总的元数据。

5. 外观设计

USD755693S1 Automotive wheel 有权
公开(公告)号：USD755693S1
公开(公告)日：2016-05-10
申请号：US29515748
申请日：2015-01-26
申请人： Kevin Lee
设计人： Kevin Lee

6. 发明申请

US20150191987A1 Underwater Noise Abatement Apparatus and Deployment System 有权
标题翻译：水下消声装置及部署系统
公开(公告)号：US20150191987A1
公开(公告)日：2015-07-09
申请号：US14590177
申请日：2015-01-06
申请人： Mark Wochner , Andrew McNeese , Preston Wilson , Kevin Lee
发明人： Mark Wochner , Andrew McNeese , Preston Wilson , Kevin Lee
IPC分类号： E21B33/10
CPC分类号： E21B33/10 , E21B41/0007 , G10K11/172 , G10K2200/11
摘要： A deployable underwater noise abatement system allowing packing and deploying an organized set of grouped resonators is disclosed. The system allows relatively compact storage and transportation of the noise abatement apparatus when not in use, then, when deployed, the apparatus can be lowered into the water and extended.
摘要翻译：公开了一种可部署的水下噪声消除系统，允许打包和部署一组有组织的分组谐振器。该系统在不使用时允许噪声消除装置的相对紧凑的存储和运输，然后在部署时，该装置可以被降低到水中并延伸。

7. 外观设计

USD706193S1 Automotive wheel 有权
公开(公告)号：USD706193S1
公开(公告)日：2014-06-03
申请号：US29467764
申请日：2013-09-23
申请人： Kevin Lee
设计人： Kevin Lee

8. 发明申请

US20140058515A1 SURFACE EXPANDING SPACER 有权
标题翻译：表面膨胀间隔
公开(公告)号：US20140058515A1
公开(公告)日：2014-02-27
申请号：US13797174
申请日：2013-03-12
申请人： John Riley Hawkins , Nicholas Pavento , Christopher Ramsay , Sean Selover , Kevin Lee
发明人： John Riley Hawkins , Nicholas Pavento , Christopher Ramsay , Sean Selover , Kevin Lee
IPC分类号： A61F2/44
CPC分类号： A61F2/4455 , A61F2/4601 , A61F2/4611 , A61F2/4644 , A61F2002/30523 , A61F2002/30571 , A61F2002/30579 , A61F2002/30594 , A61F2002/30772 , A61F2002/4627 , A61F2002/4629 , A61F2002/4645
摘要： An interbody spacer comprising a series of stacked walls connected by a common base, wherein the spacer collapses when pressed into an access delivery tube. During insertion, the walls can flex as a unit, like bending a deck of cards, to traverse bends in the access tube. Upon distally exiting the portal of the access delivery tube, the walls track apart (like spreading fingers) to create a wide base of support for the vertebral body endplate. A graft delivery device that uses a conveyor belt-type approach to deliver bone graft from the device to a location in a patient. In some embodiments, the conveyor-belt is manually actuated.
摘要翻译：一种体间隔离物，其包括通过共同基底连接的一系列堆叠壁，其中当压入进入输送管时，间隔件塌陷。在插入过程中，墙壁可以作为一个单元弯曲，如弯曲一叠卡片，以便在通道管中横越弯曲。在远端离开进入输送管的入口时，壁分开（如扩散手指），以形成用于椎体终板的宽基座。移植物输送装置，其使用输送带式方法将骨移植物从装置输送到患者的位置。在一些实施例中，手动致动传送带。

9. 发明授权

US08421397B2 System and method for fast start-up of an induction motor 有权
标题翻译：感应电动机快速启动的系统和方法
公开(公告)号：US08421397B2
公开(公告)日：2013-04-16
申请号：US13083849
申请日：2011-04-11
申请人： Anbo Yu , Lei Zhang , Kevin Lee
发明人： Anbo Yu , Lei Zhang , Kevin Lee
IPC分类号： H02P1/26
CPC分类号： H02P1/28 , H02P29/032
摘要： A system for controlling operation of a motor drive during fast start-up of an induction motor is disclosed. The system includes an AC motor drive having a PWM inverter and a control system to generate a command signal to cause the PWM inverter to control an output of the AC motor drive. The control system includes a start-up modulator that is selectively operable during start-up acceleration of the AC motor, the start-up modulator programmed to determine a motor current applied to the AC motor and a voltage of a DC bus, generate a first frequency offset that causes a frequency reference of the command signal to be decreased when the motor current is greater than a reference current threshold, and generate a second frequency offset that causes the frequency reference of the command signal to be increased when the DC bus voltage is greater than a reference voltage threshold.
摘要翻译：公开了一种用于在感应电动机的快速启动期间控制电动机驱动器的操作的系统。该系统包括具有PWM逆变器的AC电动机驱动器和用于产生指令信号以使PWM逆变器控制AC电动机驱动器的输出的控制系统。控制系统包括启动调制器，其可在AC电动机的启动加速期间选择性地工作，所述启动调制器被编程以确定施加到AC电动机的电动机电流和DC总线的电压，产生第一当电动机电流大于参考电流阈值时，导致指令信号的频率参考值减小的频率偏移，并且产生第二频率偏移，当DC总线电压为DC时，使得命令信号的频率参考值增加大于参考电压阈值。

10. 外观设计

USD675972S1 Automotive wheel 有权
公开(公告)号：USD675972S1
公开(公告)日：2013-02-12
申请号：US29429520
申请日：2012-08-13
申请人： Kevin Lee
设计人： Kevin Lee

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