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1. 发明授权

US07466131B1 System and method for designing multi-channel RF pulses for MR imaging 有权
标题翻译：用于MR成像设计多通道RF脉冲的系统和方法
公开(公告)号：US07466131B1
公开(公告)日：2008-12-16
申请号：US11738225
申请日：2007-04-20
申请人： Dan Xu , Kevin F. King , Zhi-Pei Liang
发明人： Dan Xu , Kevin F. King , Zhi-Pei Liang
IPC分类号： G01V3/00
CPC分类号： G01R33/4836 , G01R33/4824 , G01R33/4833
摘要： A system and method are provided for designing RF pulses for multi-channel and/or multi-dimensional spatially-selective applications using a linear approximation. Embodiments of the system and method may use a generalized linear-class large tip angle approximation to design RF pulses for multi-channel and parallel transmission. Further, some of these approximations allow for the design of arbitrarily large flip angles, irregularly-shaped flip angle profiles, or arbitrary initial magnetization values. Embodiments of the system and method may also provide for the design of k-space trajectories which aid in maintaining assumptions of the various linear class approximations.
摘要翻译：提供了一种系统和方法，用于使用线性近似来设计用于多通道和/或多维空间选择性应用的RF脉冲。该系统和方法的实施例可以使用广义线性级大尖角近似来设计用于多通道和并行传输的RF脉冲。此外，这些近似中的一些允许设计任意大的翻转角，不规则形状的翻转轮廓或任意的初始磁化值。系统和方法的实施例还可以提供有助于维持各种线性类近似的假设的k空间轨迹的设计。

2. 发明申请

US20080238425A1 SYSTEM AND METHOD FOR DESIGNING IMPROVED RF PULSE PROFILES 有权
标题翻译：用于设计改进的RF脉冲轮廓的系统和方法
公开(公告)号：US20080238425A1
公开(公告)日：2008-10-02
申请号：US11694617
申请日：2007-03-30
申请人： Dan Xu , Kevin F. King , Zhi-Pei Liang
发明人： Dan Xu , Kevin F. King , Zhi-Pei Liang
IPC分类号： G01R33/32
CPC分类号： G01R33/4833
摘要： A system and method are provided for designing RF pulses which have improved magnetization profiles. By utilizing an optimal control approach as an alternative to, or in combination with, non-iterative approximations, RF pulses generated by the system and method described herein will exhibit less deviation from that of “ideal” Bloch solutions. Consequently, the magnetization profiles produced by the RF pulses generated by the system and method described herein will be closer to the desired profiles. In addition, limitations of non-iterative approximations, such as maximum tip angle limits and linearity constraints, can be avoided.
摘要翻译：提供了一种用于设计具有改进的磁化分布的RF脉冲的系统和方法。通过利用最优控制方法作为非迭代近似的替代方案或与非迭代近似组合，由本文描述的系统和方法产生的RF脉冲将表现出与“理想”Bloch解决方案的偏差较小的偏差。因此，由本文所述的系统和方法产生的RF脉冲产生的磁化曲线将更接近所需的轮廓。此外，可以避免非迭代近似的限制，例如最大尖角限制和线性约束。

3. 发明授权

US07705594B2 System and method for designing improved RF pulse profiles 有权
标题翻译：用于设计改进的RF脉冲谱的系统和方法
公开(公告)号：US07705594B2
公开(公告)日：2010-04-27
申请号：US11694617
申请日：2007-03-30
申请人： Dan Xu , Kevin F. King , Zhi-Pei Liang
发明人： Dan Xu , Kevin F. King , Zhi-Pei Liang
IPC分类号： G01V3/00
CPC分类号： G01R33/4833
摘要： A system and method are provided for designing RF pulses which have improved magnetization profiles. By utilizing an optimal control approach as an alternative to, or in combination with, non-iterative approximations, RF pulses generated by the system and method described herein will exhibit less deviation from that of “ideal” Bloch solutions. Consequently, the magnetization profiles produced by the RF pulses generated by the system and method described herein will be closer to the desired profiles. In addition, limitations of non-iterative approximations, such as maximum tip angle limits and linearity constraints, can be avoided.
摘要翻译：提供了一种用于设计具有改进的磁化分布的RF脉冲的系统和方法。通过利用最优控制方法作为非迭代近似的替代方案或与非迭代近似组合，由本文描述的系统和方法产生的RF脉冲将显示出与“理想”Bloch解决方案的偏差较小的偏差。因此，由本文所述的系统和方法产生的RF脉冲产生的磁化曲线将更接近所需的轮廓。此外，可以避免非迭代近似的限制，例如最大尖角限制和线性约束。

4. 发明授权

US07592809B1 Hybrid k-t method of dynamic imaging with improved spatiotemporal resolution 有权
标题翻译：动态成像的混合k-t方法具有改进的时空分辨率
公开(公告)号：US07592809B1
公开(公告)日：2009-09-22
申请号：US11287184
申请日：2005-11-23
申请人： Kevin F. King , Dan Xu , Zhi-Pei Liang
发明人： Kevin F. King , Dan Xu , Zhi-Pei Liang
IPC分类号： G01V3/00
CPC分类号： G01R33/5611 , G01R33/56308
摘要： Variable-density (VD), sequentially-interleaved sampling of k-space coupled with the acquisition of reference frames of data is carried out to improve spatiotemporal resolution, image quality, and signal-to-noise ratio (SNR) of dynamic images. In one example, ktSENSE is implemented with a non-static regularization image, such as that provided by RIGR or similar technique, to acquire and reconstruct dynamic images. The integration of ktSENSE and RIGR, for example, provides dynamic images with higher spatiotemporal resolution and lower image artifacts compared to dynamic images acquired and reconstructed using ktSENSE alone.
摘要翻译：执行可变密度（VD），与数据参考帧的采集相结合的k空间的顺序交错采样，以改善动态图像的时空分辨率，图像质量和信噪比（SNR）。在一个示例中，ktSENSE通过诸如由RIGR或类似技术提供的非静态正则化图像来实现以获取和重建动态图像。例如，与使用ktSENSE单独获取和重建的动态图像相比，ktSENSE和RIGR的集成提供了具有更高时空分辨率和较低图像伪影的动态图像。

5. 发明授权

US06784664B2 Fast method for dynamic MR imaging 有权
标题翻译：动态MR成像的快速方法
公开(公告)号：US06784664B2
公开(公告)日：2004-08-31
申请号：US10317462
申请日：2002-12-11
申请人： Zhi-Pei Liang , Norbert J. Pelc
发明人： Zhi-Pei Liang , Norbert J. Pelc
IPC分类号： G01V300
CPC分类号： G01R33/561 , G01R33/4824 , G01R33/56308
摘要： Generalized series-based image reconstruction as used in dynamic imaging for high-speed imaging with limited k-space coverage for each time frame. Further, in acquiring low resolution data for a plurality of image frames, a full k-space data set is generated for each time frame with the measured low-resolution data and high spatial frequency data generated by the GS model constructed based on the high-resolution image(s). The algorithms of the invention have computational complexity of O(N log N) and arc capable of producing high-resolution dynamic images with a small number of Fourier transform samples.
摘要翻译：广泛的基于系列的图像重建，用于动态成像，用于高速成像，每个时间帧有限的k空间覆盖。此外，在获取多个图像帧的低分辨率数据时，针对每个时间帧生成具有所测量的低分辨率数据和由基于高分辨率图像构建的GS模型生成的高空间频率数据的全k空间数据集，分辨率图像。本发明的算法具有O（N log N）和弧的计算复杂度，其能够产生具有少量傅立叶变换样本的高分辨率动态图像。

6. 发明授权

US6088611A Model based method for high resolution dynamic imaging 失效
标题翻译：基于模型的高分辨率动态成像方法
公开(公告)号：US6088611A
公开(公告)日：2000-07-11
申请号：US516789
申请日：1995-08-18
申请人： Paul C. Lauterbur , Zhi-Pei Liang , Hong Jiang
发明人： Paul C. Lauterbur , Zhi-Pei Liang , Hong Jiang
IPC分类号： A61B5/055 , G01R33/561 , A61B5/00
CPC分类号： G01R33/561 , A61B5/055 , G01R33/56308 , Y10S378/901
摘要： Described here, is a method for obtaining high-resolution snap-shot images of moving objects in MR imaging applications through the elimination of ghosting and other image artifacts by estimating motion frequency data, estimating amplitude data for the motion frequency data, interpolating the motion frequency data and the amplitude data to generate snap-shot data frames, and generating snapshot images of each data frame.
摘要翻译：这里描述的是通过估计运动频率数据，估计运动频率数据的幅度数据，内插运动频率来获得MR成像应用中的移动物体的高分辨率快照图像的方法，通过消除重影和其他图像伪像数据和振幅数据以产生快照数据帧，并且生成每个数据帧的快照图像。

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