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1. 发明申请

US20080208291A1 FREQUENCY SHIFT KEYING (FSK) MAGNETIC TELEMETRY FOR IMPLANTABLE MEDICAL DEVICES AND ASSOCIATED SYSTEMS AND METHODS 审中-公开
标题翻译：用于可移植医疗设备和相关系统和方法的频移键控（FSK）磁电报
公开(公告)号：US20080208291A1
公开(公告)日：2008-08-28
申请号：US11923553
申请日：2007-10-24
申请人： Kent Leyde , Michael Bland
发明人： Kent Leyde , Michael Bland
IPC分类号： A61N1/08
CPC分类号： G01D21/00 , A61B5/0031
摘要： A telemetry receive unit for use in an implantable medical device or system can include a coil unit, a single-bit analog to digital converter (ADC), a finite impulse response filter (FIR) coupled to the single-bit ADC, and an accumulator coupled to one or more filter taps of the FIR filter. The accumulator, in operation, can produce one or more data recognition signals corresponding to sampled bits at least temporarily stored at the FIR filter. In several examples, the data recognition signals discriminate between frequency modulated signals that are received at the coil unit, including frequency shift keying (FSK) modulated signals.
摘要翻译：用于可植入医疗设备或系统的遥测接收单元可以包括线圈单元，单比特模数转换器（ADC），耦合到单比特ADC的有限脉冲响应滤波器（FIR）和累加器耦合到FIR滤波器的一个或多个滤波器抽头。在操作中，累加器可以产生一个或多个对应于至少临时存储在FIR滤波器的采样位的数据识别信号。在几个示例中，数据识别信号区分在线圈单元接收的频率调制信号，包括频移键控（FSK）调制信号。

2. 发明授权

US09788744B2 Systems for monitoring brain activity and patient advisory device 有权
公开(公告)号：US09788744B2
公开(公告)日：2017-10-17
申请号：US12180996
申请日：2008-07-28
申请人： Michael Bland , Kent W. Leyde , Neil G. McIlvaine , Shan Gaw , Peter Weiss , John F. Harris
发明人： Michael Bland , Kent W. Leyde , Neil G. McIlvaine , Shan Gaw , Peter Weiss , John F. Harris
IPC分类号： A61B5/04 , A61B5/0478 , A61B5/042 , A61B5/0432 , A61B5/044 , A61B5/0448 , A61B5/0476 , A61B5/0496 , A61B5/00
CPC分类号： A61B5/0476 , A61B5/0031 , A61B5/4094
摘要： A patient advisory device (“PAD”) and its methods of use. The PAD may be configured to alert the patient about an estimated brain state of the patient. In preferred embodiments, the PAD is adapted to alert the patient of the patient's brain state, which corresponds to the patient's propensity of transitioning into an ictal brain state, e.g., having a seizure. Based on the specific type of alert, the patient will be made aware whether they are highly unlikely to have a seizure for a given period of time, an elevated propensity of having a seizure, a seizure is occurring or imminent, or the patient's brain state is unknown.

3. 发明授权

US09643019B2 Neurological monitoring and alerts 有权
公开(公告)号：US09643019B2
公开(公告)日：2017-05-09
申请号：US13026961
申请日：2011-02-14
申请人： Jason A. Higgins , Michael Bland , Kent W. Leyde , W. Douglas Sheffield , John F. Harris , David M. Himes
发明人： Jason A. Higgins , Michael Bland , Kent W. Leyde , W. Douglas Sheffield , John F. Harris , David M. Himes
IPC分类号： A61B5/04 , A61N1/372 , A61B5/00 , A61N1/00 , A61N1/05
CPC分类号： A61N1/37258 , A61B5/4094 , A61N1/00 , A61N1/0529 , G16H40/67
摘要： A system for providing alerts of neurological events occurring in a human subject is provided. The system includes: a monitoring module adapted to detect and sample a neurological signal; an event detection module coupled to the monitoring module for detecting one or more types of predetermined reportable events based on the detected neurological signal; and an alert module coupled to the event detection module, wherein upon the detection of a reportable event by the event detection module, said alert module selects a first alert contact from a plurality of contacts contained in a contact list, and generates a first alert communication to the first alert contact.

4. 发明申请

US20110201944A1 NEUROLOGICAL MONITORING AND ALERTS 有权
标题翻译：神经监测和警报
公开(公告)号：US20110201944A1
公开(公告)日：2011-08-18
申请号：US13026961
申请日：2011-02-14
申请人： Jason A. Higgins , Michael Bland , Kent W. Leyde , W. Douglas Sheffield , John F. Harris , David M. Himes
发明人： Jason A. Higgins , Michael Bland , Kent W. Leyde , W. Douglas Sheffield , John F. Harris , David M. Himes
IPC分类号： A61B5/0205 , A61B5/0476 , A61N1/36
CPC分类号： A61N1/37258 , A61B5/4094 , A61N1/00 , A61N1/0529 , G16H40/67
摘要： A system for providing alerts of neurological events occurring in a human subject is provided. The system includes: a monitoring module adapted to detect and sample a neurological signal; an event detection module coupled to the monitoring module for detecting one or more types of predetermined reportable events based on the detected neurological signal; and an alert module coupled to the event detection module, wherein upon the detection of a reportable event by the event detection module, said alert module selects a first alert contact from a plurality of contacts contained in a contact list, and generates a first alert communication to the first alert contact.
摘要翻译：提供了一种用于提供在人类受试者中发生的神经系统事件的警报的系统。该系统包括：适于检测和采样神经信号的监测模块; 事件检测模块，耦合到监视模块，用于基于检测到的神经信号检测一种或多种类型的预定可报告事件; 以及耦合到所述事件检测模块的警报模块，其中当所述事件检测模块检测到可报告事件时，所述警报模块从包含在联系人列表中的多个联系人中选择第一警报联系人，并且生成第一警报通信到第一个警报联系人。

5. 发明申请

US20220387482A1 PERFORMANCE ENHANCEMENT DELIVERY SYSTEM 有权
公开(公告)号：US20220387482A1
公开(公告)日：2022-12-08
申请号：US17803148
申请日：2022-03-04
申请人： Michael Bland
发明人： Michael Bland
IPC分类号： A61K33/00 , A61K31/122 , A61K31/198 , A61P3/02 , A23L33/105 , A23L33/155 , A23L33/175 , A23L33/16 , A23L33/125 , A23P10/30 , A23P10/40
摘要： The present disclosure provides an improvement of existing L-arginine containing supplements by providing both hydrogen crystals (H2) and co-enzyme Q10 (Co-Q10) to produce a nutrient formulation, including compositions containing said formulation and methods of administering such formulation.

6. 发明申请

US20090171168A1 Systems and Method for Recording Clinical Manifestations of a Seizure 审中-公开
标题翻译：记录癫痫发作临床表现的系统和方法
公开(公告)号：US20090171168A1
公开(公告)日：2009-07-02
申请号：US12343376
申请日：2008-12-23
申请人： Kent W. Leyde , Michael Bland
发明人： Kent W. Leyde , Michael Bland
IPC分类号： A61B5/0476 , A61B5/024
CPC分类号： A61B5/4094 , A61B5/0031 , A61B5/04012 , A61B5/0478 , A61B5/048 , A61B5/11 , A61B5/7221 , A61B5/7246 , A61B5/7275 , A61N1/36082
摘要： A method of comparing a patient's neurological data to data that is indicative of the patient's clinical manifestation of a seizure. In some embodiments, the method includes the steps of monitoring neurological data from a patient indicative of the patient's propensity for having a seizure; automatically recording clinical manifestation data from the patient that may be indicative of the occurrence of a clinical seizure; and analyzing the automatically recorded clinical manifestation data and the monitored neurological data to determine if one of the clinical manifestation data and the neurological data indicates the occurrence of a seizure while the other does not. Systems are described including a monitoring device having a communication assembly for receiving neurological data transmitted external to a patient from a transmitter implanted in a patient; a processor that processes the neurological data to estimate the patient's brain state; and an assembly for automatically recording clinical manifestation data in response to a brain state estimate by the processor.
摘要翻译：将患者的神经学数据与指示患者临床表现为癫痫发作的数据进行比较的方法。在一些实施例中，该方法包括以下步骤：监测来自患者的指示患者癫痫发作倾向的神经学数据; 自动记录患者临床表现资料，可能表明临床发作的发生; 并分析自动记录的临床表现数据和所监测的神经学数据，以确定临床表现数据和神经学数据之一是否表明癫痫发作，而另一个不发生。描述了系统，其包括具有通信组件的监视设备，该通信组件用于从植入患者体内的发射器接收从患者外部传输的神经学数据; 处理器，处理神经学数据以估计患者的大脑状态; 以及用于响应于处理器的脑状态估计自动记录临床表现数据的组件。

7. 发明申请

US20090062682A1 Patient Advisory Device 有权
标题翻译：患者咨询设备
公开(公告)号：US20090062682A1
公开(公告)日：2009-03-05
申请号：US12180996
申请日：2008-07-28
申请人： Michael Bland , Kent W. Leyde , Neil G. McIlvaine , Shan Gaw , Peter Weiss , John F. Harris
发明人： Michael Bland , Kent W. Leyde , Neil G. McIlvaine , Shan Gaw , Peter Weiss , John F. Harris
IPC分类号： A61B5/0476
CPC分类号： A61B5/0476 , A61B5/0031 , A61B5/4094
摘要： A patient advisory device (“PAD”) and its methods of use. The PAD may be configured to alert the patient about an estimated brain state of the patient. In preferred embodiments, the PAD is adapted to alert the patient of the patient's brain state, which corresponds to the patient's propensity of transitioning into an ictal brain state, e.g., having a seizure. Based on the specific type of alert, the patient will be made aware whether they are highly unlikely to have a seizure for a given period of time, an elevated propensity of having a seizure, a seizure is occurring or imminent, or the patient's brain state is unknown.
摘要翻译：患者咨询器（“PAD”）及其使用方法。 PAD可以被配置为警告患者关于患者的估计的脑状态。在优选实施例中，PAD适于警告患者患者的脑状态，其对应于患者转变为脑血管状态的倾向，例如具有癫痫发作。根据具体的警戒类型，患者将会意识到他们是否不太可能在给定的时间内癫痫发作，癫痫发作，癫痫发作或迫在眉睫的倾向，或患者的大脑状态是未知数

8. 发明授权

US08976542B2 High frequency cathode heater supply for a microwave source 有权
标题翻译：高频阴极加热器用于微波源
公开(公告)号：US08976542B2
公开(公告)日：2015-03-10
申请号：US13509191
申请日：2010-11-11
申请人： Robert Richardson , Michael Bland , Colin Bennett
发明人： Robert Richardson , Michael Bland , Colin Bennett
IPC分类号： H01J23/34 , H02M3/335 , H05B6/66 , H01J1/13 , H01J23/05 , H01J25/52 , H01J25/587
CPC分类号： H01J1/135 , H01J23/05 , H01J25/52 , H01J25/587
摘要： A high frequency cathode heater supply for a microwave source includes a SMPS inverter and an isolation transformer having a primary winding arranged to be powered by the SMPS inverter, a monitor winding passing through primary core assemblies of the primary winding and a secondary winding arranged for connection to the cathode heater. A current monitor is arranged to monitor a current in the primary windings. Signal processing modules are arranged to receive a first input signal from the monitor winding indicative of a voltage across the cathode heater and a second input signal from the current monitor indicative of a current through the cathode heater. The signal processing modules are arranged to output a control signal to the SMPS inverter to control power supplied to the cathode heater dependent on a monitored resistance of, or monitored power supplied to, the cathode heater as determined from the first input signal and the second input signal.
摘要翻译：用于微波源的高频阴极加热器电源包括SMPS逆变器和隔离变压器，其具有布置成由SMPS逆变器供电的初级绕组，通过初级绕组的初级芯组件的监视器绕组和布置成用于连接的次级绕组到阴极加热器。电流监视器用于监视初级绕组中的电流。信号处理模块被布置成从监视器绕组接收指示阴极加热器两端的电压的第一输入信号和来自电流监视器的指示通过阴极加热器的电流的第二输入信号。所述信号处理模块被布置为根据从所述第一输入信号和所述第二输入确定的所述阴极加热器的被监视电阻或监视的功率来控制向所述阴极加热器供电的功率，以输出控制信号到所述SMPS逆变器信号。

9. 发明申请

US20120280619A1 HIGH FREQUENCY CATHODE HEATER SUPPLY FOR A MICROWAVE SOURCE 有权
标题翻译：用于微波源的高频CATHODE加热器供应
公开(公告)号：US20120280619A1
公开(公告)日：2012-11-08
申请号：US13509191
申请日：2010-11-11
申请人： Robert Richardson , Michael Bland , Colin Bennett
发明人： Robert Richardson , Michael Bland , Colin Bennett
IPC分类号： H01J23/34
CPC分类号： H01J1/135 , H01J23/05 , H01J25/52 , H01J25/587
摘要： A high frequency cathode heater supply for a microwave source includes a SMPS inverter and an isolation transformer having a primary winding arranged to be powered by the SMPS inverter, a monitor winding passing through primary core assemblies of the primary winding and a secondary winding arranged for connection to the cathode heater. A current monitor is arranged to monitor a current in the primary windings. Signal processing modules are arranged to receive a first input signal from the monitor winding indicative of a voltage across the cathode heater and a second input signal from the current monitor indicative of a current through the cathode heater. The signal processing modules are arranged to output a control signal to the SMPS inverter to control power supplied to the cathode heater dependent on a monitored resistance of, or monitored power supplied to, the cathode heater as determined from the first input signal and the second input signal.
摘要翻译：用于微波源的高频阴极加热器电源包括SMPS逆变器和隔离变压器，其具有布置成由SMPS逆变器供电的初级绕组，通过初级绕组的初级芯组件的监视器绕组和布置成用于连接的次级绕组到阴极加热器。电流监视器用于监视初级绕组中的电流。信号处理模块被布置成从监视器绕组接收指示阴极加热器两端的电压的第一输入信号和来自电流监视器的指示通过阴极加热器的电流的第二输入信号。所述信号处理模块被布置为根据从所述第一输入信号和所述第二输入确定的所述阴极加热器的被监视电阻或监视的功率来控制向所述阴极加热器供电的功率，以输出控制信号到所述SMPS逆变器信号。

10. 外观设计

USD627476S1 Medical patient advisory device 有权
标题翻译：医疗顾问设备
公开(公告)号：USD627476S1
公开(公告)日：2010-11-16
申请号：US29284040
申请日：2007-08-29
申请人： Shan Gaw , Michael Bland , Peter D. Weiss , Kent W Leyde , John F. Harris
设计人： Shan Gaw , Michael Bland , Peter D. Weiss , Kent W Leyde , John F. Harris

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