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1. 发明申请

US20060272716A1 METHOD OF ADHESIVELESS LAMINATION OF POLYMER FILMS INTO MICROFLUIDIC NETWORKS WITH HIGH DIMENSIONAL FIDELITY 审中-公开
标题翻译：将聚合物薄膜粘贴到具有高维度的微流网络中的方法
公开(公告)号：US20060272716A1
公开(公告)日：2006-12-07
申请号：US11382779
申请日：2006-05-11
申请人： Kenneth Hawkins , David Markel , Paul Yager , Matthew Munson
发明人： Kenneth Hawkins , David Markel , Paul Yager , Matthew Munson
IPC分类号： F15C1/06
CPC分类号： F15C1/06 , Y10T137/2224
摘要： A method for fabricating an adhesiveless microfluidic device using solvent assisted thermal welding is provided. The method comprises use of a plurality of device layers of a bulk chemical conformation composition having a glass transition temperature that can be disrupted by a disrupting agent without total solvation, wherein the plurality of device layers when assembled define a plurality of defined component features. The device layers are immersed into the disrupting agent for a time period sufficient to disrupt the glass transition temperature of a defined depth of the surfaces of the device layers prior to their removal from the disrupting agent. The plurality of device layers are assembled and registered by contacting the plurality of device layer surfaces to form the defined component features. Pressure and heat are simultaneously applied to bring the assembly to a temperature below the pressure-specific, glass transition temperature of the bulk chemical conformation composition; but above the pressure-specific, glass transition temperature of the disrupted surface layer of the composition, for a time period sufficient to affect a weld between the contacted surfaces of the plurality of device layers. The temperature of the assembly is reduced over a time period sufficient to anneal the contacted surfaces of the plurality of device layers to form the microfluidic device.
摘要翻译：提供了使用溶剂辅助热焊接制造无粘合微流体装置的方法。该方法包括使用大量化学构象组合物的多个器件层，其具有玻璃化转变温度，所述玻璃化转变温度可被破坏剂破坏而不具有全部溶剂化，其中所述多个器件层在组装时限定多个限定的部件特征。将装置层浸入破碎剂中足以破坏装置层的表面的规定深度的玻璃化转变温度，然后再将其从干扰剂中除去。多个器件层通过接触多个器件层表面来组装和注册以形成限定的部件特征。同时施加压力和热量以使组件达到低于本体化学构象组合物的压力特定玻璃化转变温度的温度; 但高于组合物破坏的表面层的压力特定的玻璃化转变温度，持续足以影响多个器件层的接触表面之间的焊接的时间段。组件的温度在足以退火多个器件层的接触表面以形成微流体器件的时间段内减小。

2. 发明申请

US20060166375A1 Microscale diffusion immunoassay utilizing multivalent reactants 有权
公开(公告)号：US20060166375A1
公开(公告)日：2006-07-27
申请号：US11226054
申请日：2005-09-14
申请人： Kenneth Hawkins , Paul Yager
发明人： Kenneth Hawkins , Paul Yager
IPC分类号： G01N33/551
CPC分类号： G01N33/558 , B01L3/5027 , B01L2200/0636 , G01N33/54366 , Y10T436/117497 , Y10T436/118339 , Y10T436/2575
摘要： An improved microscale diffusion immunoassay utilizing multivalent reactants is disclosed. In particular, a method for detecting the presence of analyte particles in an analyte fluid is disclosed, the method comprising: (a) providing the analyte fluid comprising the analyte particles; (b) providing a diffusion fluid comprising binding particles capable of binding with the analyte particles; (c) flowing the analyte fluid and the diffusion fluid in adjacent laminar flow through a microfluidic channel; (d) allowing the analyte particles to diffuse into the diffusion fluid and bind with the binding particles to form analyte/binding particle complexes; and (e) detecting the presence of the analyte particles and the analyte/binding particle complexes, wherein each of the binding particles is capable of binding with more than one analyte particle, and wherein each of the analyte particles is capable of binding with more than one binding particle. Methods for determining the concentration of the analyte particles are also disclosed.

3. 发明授权

US07011791B2 Microfluidic devices for rotational manipulation of the fluidic interface between multiple flow streams 有权
标题翻译：用于旋转操纵多个流动之间的流体界面的微流体装置
公开(公告)号：US07011791B2
公开(公告)日：2006-03-14
申请号：US09956467
申请日：2001-09-18
申请人： Bernhard H. Weigl , Ronald L. Bardell , Andrew Kamholz , Matthew Munson , Eric Schilling , Kenneth Hawkins
发明人： Bernhard H. Weigl , Ronald L. Bardell , Andrew Kamholz , Matthew Munson , Eric Schilling , Kenneth Hawkins
IPC分类号： G01N21/00 , G01N31/22 , G01N15/06 , G01N33/00 , G01N33/48
CPC分类号： F15C1/14 , B01F5/0646 , B01F5/0647 , B01F13/0059 , B01F13/0093 , B01F15/0203 , B01F15/0233 , B01F2005/0031 , B01F2215/0431 , B01J19/0093 , B01L3/502776 , B01L2200/0621 , B01L2200/0636 , B01L2300/0867 , B01L2300/087 , B01L2300/0874 , B01L2300/161 , B01L2400/0406 , B01L2400/0457 , B01L2400/0655 , B01L2400/0688 , F16K99/0001 , F16K2099/0074 , F16K2099/0078 , F16K2099/008 , F16K2099/0084 , G01N21/07 , G01N2035/00237 , G01N2035/00495 , Y10T436/11 , Y10T436/117497 , Y10T436/118339 , Y10T436/25 , Y10T436/2575
摘要： Microfluidic devices and methods are provided for enhancing detection of a diffusion pattern formed by particles diffusing between at least two fluid streams in parallel laminar flow such that an interface is formed between them by increasing the dimension of the streams in the diffusion direction. This may be accomplished by flowing the streams through a transforming turn, or by flowing the streams through a channel having diverging walls. Devices and methods are also provided for enhancing diffusion between two streams comprising changing the interface between said streams from a narrow interface to a broad interface.
摘要翻译：提供了微流体装置和方法，用于增强由在平行层流中的至少两个流体流之间扩散的颗粒形成的扩散图案的检测，使得通过增加流在扩散方向上的尺寸而在它们之间形成界面。这可以通过使流流经转化回转，或者使流流过具有发散壁的通道来实现。还提供了用于增强两个流之间的扩散的装置和方法，包括将所述流之间的界面从窄界面改变为宽界面。

4. 发明申请

US20060005764A1 Transfer glue system and method for a right angle gluing machine 失效
公开(公告)号：US20060005764A1
公开(公告)日：2006-01-12
申请号：US11208685
申请日：2005-08-22
申请人： Joseph Walsh , Kenneth Hawkins
发明人： Joseph Walsh , Kenneth Hawkins
IPC分类号： B05B15/02 , B05C5/00
CPC分类号： B31B50/00 , B31B50/624 , B31B50/81 , B31B2105/00 , B31B2120/20 , B31B2241/001 , Y10T156/1798
摘要： Disclosed herein is a method and apparatus for applying adhesive to packaging in a variety of configurations. The adhesive may be applied by a nozzle in a first direction, a second direction and a stationary spot, wherein the first direction and the second direction are transverse to each other.

5. 发明授权

US07097676B2 Process and device for producing hydrogen 有权
标题翻译：生产氢气的方法和装置
公开(公告)号：US07097676B2
公开(公告)日：2006-08-29
申请号：US11005537
申请日：2004-12-06
申请人： Norman Wootan , Kenneth Hawkins
发明人： Norman Wootan , Kenneth Hawkins
IPC分类号： C10J3/00
CPC分类号： C10J3/56 , B01J19/088 , B01J19/246 , B01J2219/00121 , B01J2219/0263 , B01J2219/0813 , B01J2219/0869 , B01J2219/0886 , C01B3/06 , C10J3/54 , C10J2200/09 , C10J2300/093 , C10J2300/0936 , C10J2300/0973 , C10J2300/1646 , Y02E60/36
摘要： A process and a device are provided for producing hydrogen gas from water and carbon. The process includes introducing steam and powdered carbon in stoichiometric ratio of carbon to water into a preheated oxidization chamber in such a way that a gas plasma is produced in which the steam is decomposed into its hydrogen and oxygen gas components and oxygen is combined with carbon to form carbon dioxide gas in an exothermic reaction at temperatures above 2000° C., and separating the carbon dioxide gas from the hydrogen gas. The device for conducting this process has an oxidization chamber defined in a hollow body and being provided with a preheater and having at least one inlet port for introducing steam into the oxidization chamber, at least one inlet port for introducing powdered carbon into the oxidization chamber, and at least one exit port for carrying off generated hydrogen gas and/or generated carbon dioxide gas from the oxidization chamber.
摘要翻译：提供了一种从水和碳生产氢气的方法和装置。该方法包括将碳与水的化学计量比的蒸汽和粉末碳引入预热的氧化室中，使得产生气体等离子体，其中蒸汽分解成其氢气，氧气组分和氧气与碳组合在高于2000℃的温度下在放热反应中形成二氧化碳气体，并将二氧化碳气体与氢气分离。用于进行该方法的装置具有限定在中空体中的氧化室，并且设置有预热器，并具有用于将蒸汽引入氧化室的至少一个入口端口，用于将粉末碳引入氧化室的至少一个入口端口，以及至少一个用于从氧化室中产生的氢气和/或产生的二氧化碳气体的出口。

6. 发明申请

US20050150164A1 Process and device for producing hydrogen 有权
标题翻译：生产氢气的方法和装置
公开(公告)号：US20050150164A1
公开(公告)日：2005-07-14
申请号：US11005537
申请日：2004-12-06
申请人： Norman Wootan , Kenneth Hawkins
发明人： Norman Wootan , Kenneth Hawkins
IPC分类号： B01J19/08 , B01J19/24 , C01B3/06 , C10J3/54 , C10J3/56 , C01B3/02
CPC分类号： C10J3/56 , B01J19/088 , B01J19/246 , B01J2219/00121 , B01J2219/0263 , B01J2219/0813 , B01J2219/0869 , B01J2219/0886 , C01B3/06 , C10J3/54 , C10J2200/09 , C10J2300/093 , C10J2300/0936 , C10J2300/0973 , C10J2300/1646 , Y02E60/36
摘要： The invention relates to a process and a device for producing hydrogen gas from water and carbon. The process is characterized by introducing steam and powdered carbon in stoichiometric ratio of carbon to water into a preheated oxidization chamber (2) in such a way that a gas plasma is produced in which the steam is decomposed into its hydrogen and oxygen gas components and oxygen is combined with carbon to form carbon dioxide gas in an exothermic reaction at temperatures above 2000° C., and separating the carbon dioxide gas from the hydrogen gas. Accordingly, the device for conducting this process comprises an oxidization chamber (2) defined in a hollow body (1) made of a material withstanding temperatures above 2000° C., said oxidization chamber being provided with means (3, 16) for preheating the oxidization chamber and having at least one inlet port (9) for introducing steam into the oxidization chamber, at least one inlet port (10) for introducing powdered carbon into the oxidization chamber, and at least one exit port (14) for carrying off generated hydrogen gas and/or generated carbon dioxide gas from the oxidization chamber.
摘要翻译：本发明涉及从水和碳生产氢气的方法和装置。该方法的特征在于将碳与水的化学计量比的蒸汽和粉末碳引入预热的氧化室（2）中，使得产生气体等离子体，其中蒸汽分解成其氢气和氧气组分和氧气与碳结合，在高于2000℃的温度下在放热反应中形成二氧化碳气体，并将二氧化碳气体与氢气分离。因此，用于进行该方法的装置包括限定在由耐受温度高于2000℃的材料制成的中空体（1）中的氧化室（2），所述氧化室设置有用于预热氧化室，并且具有用于将蒸汽引入氧化室的至少一个入口端口（9），用于将粉末碳引入氧化室的至少一个入口端口（10）和至少一个出口来自氧化室的氢气和/或产生的二氧化碳气体。

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