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    • 1. 发明申请
    • ENDOLUMINAL PROSTHESIS
    • 内分泌疾病
    • US20140081386A1
    • 2014-03-20
    • US13618356
    • 2012-09-14
    • Kenneth A. HaselbyKeith MilnerShruti MishraSara M. Sherman
    • Kenneth A. HaselbyKeith MilnerShruti MishraSara M. Sherman
    • A61F2/06B29C47/06
    • A61F2/07A61F2/915A61F2002/072A61F2002/91575A61F2240/001A61F2250/0036
    • An endoluminal prosthesis for placement within a body vessel may include a tubular support structure including a proximal end segment, a distal end segment, an intermediate segment positioned between the proximal end segment and the distal end segment, a lumen extending longitudinally within the support structure, a luminal surface, and an abluminal surface opposite the luminal surface. The prosthesis may include a first layer of nonwoven electrospun fibers positioned on the luminal surface of the support structure. The prosthesis may include a second layer of nonwoven electrospun fibers positioned on the abluminal surface of the support structure. At least one of the proximal end segment or the distal end segment of the support structure may be encapsulated within a covering including the first layer of nonwoven electrospun fibers and the second layer of nonwoven electrospun fibers. The intermediate segment of the support structure may be unencapsulated within the covering.
    • 用于放置在体容器内的腔内假体可以包括管状支撑结构,其包括近端段,远端段,位于近端段和远端段之间的中间段,在支撑结构内纵向延伸的腔, 管腔表面和与腔表面相对的腹膜表面。 假体可以包括位于支撑结构的腔表面上的第一非织造电纺纤维层。 假体可以包括位于支撑结构的外侧表面上的第二非织造电纺纤维层。 支撑结构的近端段或远端段中的至少一个可以封装在包括非织造电纺纤维的第一层和非织造电纺纤维的第二层的覆盖物内。 支撑结构的中间段可以在封套内未被包封。
    • 2. 发明授权
    • Electrospun patterned stent graft covering
    • 电纺图案支架移植覆盖物
    • US09175427B2
    • 2015-11-03
    • US13295589
    • 2011-11-14
    • Kenneth A. HaselbyKeith R. MilnerSara M. ShermanSeoggwan KimRichard A. Swift
    • Kenneth A. HaselbyKeith R. MilnerSara M. ShermanSeoggwan KimRichard A. Swift
    • B32B3/24D04H1/728D01D5/00A61F2/07
    • D04H1/728A61F2/07A61F2250/0001D01D5/0076Y10T428/24273
    • An endoluminal prosthesis and systems and methods for making the prosthesis are provided. In one example, a patterned graft material for a prosthesis includes a network of electrospun fibers. The network of electrospun fibers may include a plurality of continuous electrospun fibers. The fibers may be collected on a collector plate using an electrospinning process to form the network of fibers. The patterned graft material also may include a plurality of openings in the network of electrospun fibers. The plurality of openings may be arranged in a pattern. The network of electrospun fibers may include a plurality of edges, each surrounding a corresponding one of the plurality of openings. Each of the plurality of edges may include at least one electrospun fiber of the network of electrospun fibers. A majority of the electrospun fibers of the plurality of edges may be continuous at the edges.
    • 提供了一种用于制造假体的腔内假体和系统和方法。 在一个实例中,用于假体的图案化移植材料包括电纺纤维网络。 电纺纤维的网络可以包括多个连续的电纺丝纤维。 可以使用电纺丝方法将纤维收集在收集板上以形成纤维网。 图案化的移植材料还可以包括电纺纤维网络中的多个开口。 多个开口可以以图案布置。 电纺纤维的网络可以包括多个边缘,每个边缘围绕多个开口中的对应的一个开口。 多个边缘中的每一个可以包括电纺纤维网络的至少一个电纺纤维。 多个边缘中的大多数电纺丝纤维可以在边缘处是连续的。