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1. 发明申请

US20140163135A1 HYDROPHILIC SILICONE MONOMERS, PROCESS FOR THEIR PREPARATION AND THIN FILMS CONTAINING THE SAME 有权
标题翻译：亲水硅胶单体，其制备方法和含有其的薄膜
公开(公告)号：US20140163135A1
公开(公告)日：2014-06-12
申请号：US14182709
申请日：2014-02-18
申请人： Kendall Louis Guyer , Kenrick Martin Lewis , Senthilkumar Umapathy , Anubhav Saxena , Yi-Feng Wang
发明人： Kendall Louis Guyer , Kenrick Martin Lewis , Senthilkumar Umapathy , Anubhav Saxena , Yi-Feng Wang
IPC分类号： C08L33/14 , G02C7/04
CPC分类号： C08L33/14 , C07F7/0838 , C07F7/21 , G02C7/04
摘要： There is provided new mono-(meth)acrylate functionalized hydrophilic silicone monomers containing a polyether with branched linking group, useful in making water absorbing silicone-hydrogel films for contact lens applications. This invention also provides homo-polymers and copolymers made from the mono-(meth)acrylate functionalized hydrophilic silicone monomers described herein. Also provided is a process for producing the monomers and polymers described herein and contact lenses produced from the same.
摘要翻译：提供了含有具有支链连接基团的聚醚的新的单（甲基）丙烯酸酯官能化亲水硅氧烷单体，可用于制备用于隐形眼镜应用的吸水硅氧烷水凝胶膜。本发明还提供由本文所述的单（甲基）丙烯酸酯官能化的亲水硅氧烷单体制备的均聚物和共聚物。还提供了制备本文所述的单体和聚合物的方法以及由其制备的隐形眼镜。

2. 发明授权

US08686099B2 Hydrophilic silicone monomers, process for their preparation and thin films containing the same 有权
标题翻译：亲水硅氧烷单体，其制备方法和含有相同的薄膜
公开(公告)号：US08686099B2
公开(公告)日：2014-04-01
申请号：US13122255
申请日：2009-10-05
申请人： Kendall Louis Guyer , Kenrick Martin Lewis , Sentihilkumar Umapathy , Anubhav Saxena , Yi-Feng Wang
发明人： Kendall Louis Guyer , Kenrick Martin Lewis , Sentihilkumar Umapathy , Anubhav Saxena , Yi-Feng Wang
IPC分类号： C08F30/08
CPC分类号： C08L33/14 , C07F7/0838 , C07F7/21 , G02C7/04
摘要： There is provided a mono-(meth)acrylate functionalized hydrophilic silicone monomers containing a polyether with branched linking group, useful in making water absorbing silicone-hydrogel films for contact lens applications. This invention also provides homo-polymers and copolymers made from the mono-(meth)acrylate functionalized hydrophilic silicone monomers described herein. Also provided is a process for producing the monomers and polymers described herein and contact lenses produced from the same.
摘要翻译：提供了含有具有支链连接基团的聚醚的单（甲基）丙烯酸酯官能化的亲水性硅氧烷单体，可用于制造用于隐形眼镜应用的吸水硅胶 - 水凝胶膜。本发明还提供由本文所述的单（甲基）丙烯酸酯官能化的亲水硅氧烷单体制备的均聚物和共聚物。还提供了制备本文所述的单体和聚合物的方法以及由其制备的隐形眼镜。

3. 发明申请

US20110181833A1 HYDROPHILIC SILICONE MONOMERS, PROCESS FOR THEIR PREPARATION AND THIN FILMS CONTAINING THE SAME 有权
标题翻译：亲水硅胶单体，其制备方法和含有其的薄膜
公开(公告)号：US20110181833A1
公开(公告)日：2011-07-28
申请号：US13122255
申请日：2009-10-05
申请人： Kendall Louis Guyer , Kenrick Martin Lewis , Sentihikumar Umapathy , Anubhav Saxena , Yi-Feng Wang
发明人： Kendall Louis Guyer , Kenrick Martin Lewis , Sentihikumar Umapathy , Anubhav Saxena , Yi-Feng Wang
IPC分类号： G02C7/04 , C07F7/08 , C07F7/21 , C08F120/28 , C08F220/28 , C08F220/56 , C08F226/08 , C08L43/04
CPC分类号： C08L33/14 , C07F7/0838 , C07F7/21 , G02C7/04
摘要： There is provided a mono-(meth)acrylate functionalized hydrophilic silicone monomers containing a polyether with branched linking group, useful in making water absorbing silicone-hydrogel films for contact lens applications. This invention also provides homo-polymers and copolymers made from the mono-(meth)acrylate functionalized hydrophilic silicone monomers described herein. Also provided is a process for producing the monomers and polymers described herein and contact lenses produced from the same.
摘要翻译：提供了含有具有支链连接基团的聚醚的单（甲基）丙烯酸酯官能化的亲水性硅氧烷单体，可用于制造用于隐形眼镜应用的吸水硅胶 - 水凝胶膜。本发明还提供由本文所述的单（甲基）丙烯酸酯官能化的亲水硅氧烷单体制备的均聚物和共聚物。还提供了制备本文所述的单体和聚合物的方法以及由其制备的隐形眼镜。

4. 发明授权

US09459378B2 Hydrophilic silicone monomers, process for preparation thereof and thin films containing the same 有权
标题翻译：亲水硅氧烷单体，其制备方法和含有它们的薄膜
公开(公告)号：US09459378B2
公开(公告)日：2016-10-04
申请号：US14492489
申请日：2014-09-22
申请人： Anubhav Saxena , Shreedhar Bhat , Senthilkumar Umapathy , Kenrick M. Lewis
发明人： Anubhav Saxena , Shreedhar Bhat , Senthilkumar Umapathy , Kenrick M. Lewis
IPC分类号： G02B1/04 , A61K8/81 , A61Q5/02 , C09D143/04 , D21H17/59 , C08F230/08 , C08G77/388 , C08G77/46 , D06M15/643 , C08G77/20
CPC分类号： G02B1/043 , A61K8/8158 , A61K8/898 , A61K2800/10 , A61Q5/02 , A61Q19/00 , C08F230/08 , C08G77/20 , C08G77/388 , C08G77/46 , C09D143/04 , D06M15/643 , D06M15/6436 , D06M2200/50 , D21H17/59 , C08F220/54 , C08F220/20 , C08F226/10 , C08F2222/1013 , C08L101/14 , C08L33/24 , C08L83/12
摘要： The present invention relates to a fast curing compositions comprising a (meth)acrylamide functionalized hydrophilic silicone monomers having a polyether moiety containing a branched linking group. In one embodiment, such compositions are useful for preparing water-absorbing silicone-hydrogel films for contact lens applications. In one embodiment, the (meth)acrylamide monomers disclosed here have a branched linking group on the polyether moiety which makes it possible to produce hydrophilic polyether modified silicone copolymers without the need to separate various by-products including, but not limited to, unreacted, isomerized polyether and associated high molecular weight by-products.
摘要翻译：本发明涉及快速固化组合物，其包含具有含有支链连接基团的聚醚部分的（甲基）丙烯酰胺官能化的亲水硅氧烷单体。在一个实施方案中，这样的组合物可用于制备用于隐形眼镜应用的吸水硅氧烷水凝胶膜。在一个实施方案中，本文公开的（甲基）丙烯酰胺单体在聚醚部分上具有支链连接基团，这使得可以制备亲水性聚醚改性的硅氧烷共聚物，而不需要分离各种副产物，包括但不限于未反应的，异构化的聚醚和相关的高分子量副产物。

5. 发明授权

US10101499B2 Hydrophilic macromers and hydrogels comprising the same 有权
公开(公告)号：US10101499B2
公开(公告)日：2018-10-16
申请号：US14492722
申请日：2014-09-22
申请人： Anubhav Saxena , Monjit Phukan , Shreedhar Bhat , Kenrick M. Lewis , Senthilkumar Umapathy
发明人： Anubhav Saxena , Monjit Phukan , Shreedhar Bhat , Kenrick M. Lewis , Senthilkumar Umapathy
IPC分类号： C08G77/20 , G02B1/04 , C08G77/46 , C08L83/04 , C08L83/08
摘要： A composition, suitable for use in producing hydrogel polymer films from which biomedical devices such as contact lenses can be made, comprising at least one hydrophilic silicone macromer. In one aspect, a hydrophilic silicone macromer is of the Formula 1: X—Si(R1)(R2)O—(Si(R3)(R4)O)a—Si(R5)(R6)—Y (1) wherein R1, R2, R3 R4, R5 and R6 are independently selected from a monovalent linear, branched, or cyclic radical with 1 to 50 carbon atoms, that can optionally contain a heteroatom or I; I is RL—RP; Y is a free radical polymerization-effective hydrophilic group with the general structure: RL—RP—Z; RL is a linking residue from a non-isomerizable hydrosilylation effective terminal olefin comprising the general structure —CH2—C(RbR7)—(CR8R9)n, the subscript n is selected from integers from 1 to 10; R7, R8, and R9 can be selected from hydrogen and a mono-valent hydrocarbon radical with 1 to 10 carbon atoms that optionally contain a heteroatom; Rb is selected from a monovalent hydrocarbon radical with 1 to 6 carbon atoms; RP is a spacer group comprising a diavelant hydrophilic organic radical with 0 to 100 carbon atoms and optionally contains heteroatoms, and X is a free radical polymerizable group. The said composition can be polymers and films suitable for use in making contact lenses.

6. 发明申请

US20150011667A1 HYDROPHILIC MACROMERS AND HYDROGELS COMPRISING THE SAME 审中-公开
标题翻译：水解胶体和包含其的水解胶
公开(公告)号：US20150011667A1
公开(公告)日：2015-01-08
申请号：US14492722
申请日：2014-09-22
申请人： Anubhav Saxena , Monjit Phukan , Shreedhar Bhat , Kenrick M. Lewis , Senthilkumar Umapathy
发明人： Anubhav Saxena , Monjit Phukan , Shreedhar Bhat , Kenrick M. Lewis , Senthilkumar Umapathy
IPC分类号： G02B1/04 , C08L83/08 , C08L83/04
CPC分类号： G02B1/043 , C08G77/20 , C08G77/46 , C08L83/04 , C08L83/08 , C08L2201/10
摘要： A composition, suitable for use in producing hydrogel polymer films from which biomedical devices such as contact lenses can be made, comprising at least one hydrophilic silicone macromer. In one aspect, a hydrophilic silicone macromer is of the Formula 1: X—Si(R1)(R2)O—(Si(R3)(R4)O)a—Si(R5)(R6)—Y (1) wherein R1, R2, R3 R4, R5 and R6 are independently selected from a monovalent linear, branched, or cyclic radical with 1 to 50 carbon atoms, that can optionally contain a heteroatom or I; I is RL-RP; Y is a free radical polymerization-effective hydrophilic group with the general structure:RL-RP—Z; RL is a linking residue from a non-isomerizable hydrosilylation effective terminal olefin comprising the general structure —CH2—C(RbR7)—(CR8R9)m, the subscript n is selected from integers from 1 to 10; R7, R8, and R9 can be selected from hydrogen and a mono-valent hydrocarbon radical with 1 to 10 carbon atoms that optionally contain a heteroatom; Rb is selected from a monovalent hydrocarbon radical with 1 to 6 carbon atoms; RP is a spacer group comprising a diavelant hydrophilic organic radical with 0 to 100 carbon atoms and optionally contains heteroatoms, and X is a free radical polymerizable group. The said composition can be polymers and films suitable for use in making contact lenses.
摘要翻译：一种适用于生产水凝胶聚合物膜的组合物，其中可以制备诸如隐形眼镜的生物医学装置，其包含至少一种亲水硅氧烷大分子单体。一方面，亲水性硅氧烷大分子单体为式1：X-Si（R1）（R2）O-（Si（R3）（R4）O）a-Si（R5）（R6）-Y（1）其中 R 1，R 2，R 3，R 4，R 5和R 6独立地选自具有1至50个碳原子的一价直链，支链或环状基团，其可任选地含有杂原子或I; 我是RL-RP; Y是具有一般结构的自由基聚合有效的亲水基团：RL-RP-Z; RL是来自包含通式-CH 2 -C（RbR 7） - （CR 8 R 9）m的非异构化氢化硅烷化有效末端烯烃的连接残基，下标n选自1至10的整数; R 7，R 8和R 9可以选自氢和具有1-10个碳原子的任选含有杂原子的一价烃基; Rb选自具有1至6个碳原子的一价烃基; RP是包含具有0至100个碳原子的疏水性亲水性有机基团并且任选地含有杂原子的间隔基，X是可自由基聚合的基团。所述组合物可以是适合用于制造隐形眼镜的聚合物和薄膜。

7. 发明申请

US20150011661A1 HYDROPHILIC SILICONE MONOMERS, PROCESS FOR PREPARATION THEREOF AND THIN FILMS CONTAINING THE SAME 有权
标题翻译：亲水硅胶单体，其制备方法和含有其的薄膜
公开(公告)号：US20150011661A1
公开(公告)日：2015-01-08
申请号：US14492489
申请日：2014-09-22
申请人： Anubhav Saxena , Shreedhar Bhat , Senthilkumar Umapathy , Kenrick M. Lewis
发明人： Anubhav Saxena , Shreedhar Bhat , Senthilkumar Umapathy , Kenrick M. Lewis
IPC分类号： G02B1/04 , A61Q5/02 , C09D143/04 , D21H17/59 , A61K8/81
CPC分类号： G02B1/043 , A61K8/8158 , A61K8/898 , A61K2800/10 , A61Q5/02 , A61Q19/00 , C08F230/08 , C08G77/20 , C08G77/388 , C08G77/46 , C09D143/04 , D06M15/643 , D06M15/6436 , D06M2200/50 , D21H17/59 , C08F220/54 , C08F220/20 , C08F226/10 , C08F2222/1013 , C08L101/14 , C08L33/24 , C08L83/12
摘要： The present invention relates to a fast curing compositions comprising a (meth)acrylamide functionalized hydrophilic silicone monomers having a polyether moiety containing a branched linking group. In one embodiment, such compositions are useful for preparing water-absorbing silicone-hydrogel films for contact lens applications. In one embodiment, the (meth)acrylamide monomers disclosed here have a branched linking group on the polyether moiety which makes it possible to produce hydrophilic polyether modified silicone copolymers without the need to separate various by-products including, but not limited to, unreacted, isomerized polyether and associated high molecular weight by-products.
摘要翻译：本发明涉及快速固化组合物，其包含具有含有支链连接基团的聚醚部分的（甲基）丙烯酰胺官能化的亲水硅氧烷单体。在一个实施方案中，这样的组合物可用于制备用于隐形眼镜应用的吸水硅氧烷水凝胶膜。在一个实施方案中，本文公开的（甲基）丙烯酰胺单体在聚醚部分上具有支链连接基团，这使得可以制备亲水性聚醚改性的硅氧烷共聚物，而不需要分离各种副产物，包括但不限于未反应的，异构化的聚醚和相关的高分子量副产物。

8. 发明申请

US20150011788A1 ORGANO-MODIFIED SILICONE POLYMERS 有权
标题翻译：有机改性硅酮聚合物
公开(公告)号：US20150011788A1
公开(公告)日：2015-01-08
申请号：US14492378
申请日：2014-09-22
申请人： Anubhav Saxena , Sandeep Shashikant Naik , Monjit Phukan , Shreedhar Bhat
发明人： Anubhav Saxena , Sandeep Shashikant Naik , Monjit Phukan , Shreedhar Bhat
IPC分类号： C07F7/18 , C07F7/21
CPC分类号： C08F283/124 , C07F7/1804 , C07F7/21 , C08F230/08 , C08G77/38 , C08G77/48 , C08G77/50 , C08G2210/00 , C08K3/20 , C08L83/14 , G02B1/043 , G02B2207/109 , C08L83/04 , C08L101/14 , C08L71/00
摘要： A linear silicone polymer suitable for use in producing homopolymers, copolymers, polymerized emulsions, latex compositions, and hydrogel polymer films. In one aspect, a hydrophilic silicone monomer is of the Formula 1: WAmBnW (1) Where, A is a divalent block comprising a silicone-containing pendant group. In one embodiment, the silicone-containing pendant group comprises polyalkylene oxide groups. The structure of the polymer can be controlled and tuned to provide a material with excellent wettability and oxygen permeability. The polymers are suitable for use in a variety of applications including in providing a film for forming contact lenses.
摘要翻译：适用于生产均聚物，共聚物，聚合乳液，胶乳组合物和水凝胶聚合物膜的线性硅氧烷聚合物。一方面，亲水性有机硅单体为式1：其中A为包含含硅氧烷的侧基的二价嵌段。在一个实施方案中，含硅氧烷的侧基包括聚环氧烷基团。可以控制和调整聚合物的结构，以提供具有优异的润湿性和透氧性的材料。该聚合物适用于各种应用，包括提供用于形成隐形眼镜的膜。

9. 发明申请

US20120323639A1 SYSTEM AND METHOD FOR DETERMINING MATURITY LEVELS FOR BUSINESS PROCESSES 审中-公开
标题翻译：用于确定业务流程成熟度的系统和方法
公开(公告)号：US20120323639A1
公开(公告)日：2012-12-20
申请号：US13162083
申请日：2011-06-16
申请人： Navin Sabharwal , Prafull Verma , Vijayakumar Chinnaswamy , Tajeshwar Singh , B Kalyan Kumar , Anubhav Saxena , Shashibhan Singh , Aushdeep Gupta , Srikrishna Ramakarthikeyan , Renju George Varghese
发明人： Navin Sabharwal , Prafull Verma , Vijayakumar Chinnaswamy , Tajeshwar Singh , B Kalyan Kumar , Anubhav Saxena , Shashibhan Singh , Aushdeep Gupta , Srikrishna Ramakarthikeyan , Renju George Varghese
IPC分类号： G06Q10/00
CPC分类号： G06Q10/067
摘要： A system, computer-readable storage medium, and computer-implemented method for determining a maturity level for a business process. Responses to questions relating to a business process for a business are received. A first business process maturity level is determined using the responses to the questions. Performance statistics are obtained from a database including historical data related to the business process. A second business process maturity level is determined using the performance statistics. A weight factor is determined using the first business process maturity level and the second business process maturity level, the weight factor corresponding to a correlation between the first business process maturity level and the second business process maturity level. A weighted business process maturity level is calculated for the business process using the first business process maturity level and the weight factor. The weighted business process maturity level for the business process is stored in the database.
摘要翻译：一种系统，计算机可读存储介质和用于确定业务流程的成熟度级别的计算机实现的方法。收到与业务业务流程相关的问题的回复。使用对问题的回答确定第一个业务流程成熟度级别。绩效统计数据是从数据库获得的，包括与业务流程相关的历史数据。使用绩效统计确定第二个业务流程成熟度级别。使用第一业务流程成熟度级别和第二业务流程成熟度级别确定权重因子，权重因子对应于第一业务流程成熟度级别和第二业务流程成熟度级别之间的相关性。使用第一个业务流程成熟度级别和权重因子为业务流程计算加权业务流程成熟度级别。业务流程的加权业务流程成熟度级别存储在数据库中。

10. 发明申请

US20120245249A1 SILOXANE MONOMERS CONTAINING HYDROLYSIS RESISTANCE CARBOSILOXANE LINKAGE, PROCESS FOR THEIR PREPARATION AND THIN FILMS CONTAINING THE SAME FOR CONTACT LENS APPLICATION 有权
标题翻译：含有水解电阻碳硅氧烷连接的硅氧烷单体，其制备用途及其接触透镜应用的薄膜
公开(公告)号：US20120245249A1
公开(公告)日：2012-09-27
申请号：US13052306
申请日：2011-03-21
申请人： Anubhav Saxena , Umapathy Senthilkumar , Kenrick M. Lewis
发明人： Anubhav Saxena , Umapathy Senthilkumar , Kenrick M. Lewis
IPC分类号： C08L43/04 , C08F230/08 , C07F7/08
CPC分类号： C08L43/04 , C07F7/0838 , C08F230/08
摘要： There is provided new mono-(meth)acrylate functionalized silicone monomers containing carbosiloxane linkage for improved hydrolysis resistance, useful in making water absorbing silicone-hydrogel films for contact lens applications. This invention also provides homo-polymers and copolymers made from the mono-(meth)acrylate functionalized hydrophilic silicone monomers described herein. Also provided is a process for producing the monomers and polymers described herein and contact lenses produced from the same.
摘要翻译：提供了含有碳硅氧烷键的新的单（甲基）丙烯酸酯官能化硅氧烷单体，以提高耐水解性，可用于制备用于隐形眼镜应用的吸水硅胶 - 水凝胶膜。本发明还提供由本文所述的单（甲基）丙烯酸酯官能化的亲水硅氧烷单体制备的均聚物和共聚物。还提供了制备本文所述的单体和聚合物的方法以及由其制备的隐形眼镜。

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