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1. 发明授权

US07863896B2 Systems and methods for calibrating functional magnetic resonance imaging of living tissue 有权
标题翻译：用于校准活组织功能磁共振成像的系统和方法
公开(公告)号：US07863896B2
公开(公告)日：2011-01-04
申请号：US12170181
申请日：2008-07-09
申请人： Keith David White
发明人： Keith David White
IPC分类号： G01V3/00
CPC分类号： G01R33/58 , G01R33/4806
摘要： Embodiments of the present invention relate to systems and methods for calibrating functional magnetic resonance imaging of living tissue. For example, a calibration method includes providing a contrast signal simulation device configured for generating one or more pre-determined contrast simulation signals selected from a group consisting of BOLD and BOSS contrast simulation signals that simulate at least one contrast signal generated by living tissue of a subject and positioning the contrast signal simulation device adjacent to the subject. The method includes using an imaging instrument to take first and second data sets from the subject's tissue while the contrast signal simulation device is disposed adjacent to the subject and while generating and not generating the one or more pre-determined contrast simulation signals, respectively. The method also includes using the first and second data sets to determine at least one figure of merit of the imaging instrument, the contrast simulation device, and/or the living tissue.
摘要翻译：本发明的实施例涉及用于校准活体组织的功能磁共振成像的系统和方法。例如，校准方法包括提供对比度信号模拟装置，该对比度信号模拟装置被配置用于生成从由BOLD和BOSS对比度模拟信号组成的组中选择的一个或多个预定对比度模拟信号，该模拟信号模拟由生物体组织产生的至少一个对比度信号对象和定位与对象相邻的对比度信号模拟设备。该方法包括使用成像仪器从对象的组织拍摄第一和第二数据集，同时对比度信号模拟装置被设置为与被摄体相邻并且同时产生并且不产生一个或多个预定的对比度模拟信号。该方法还包括使用第一和第二数据集来确定成像仪器，对比度模拟装置和/或生物体组织的至少一个品质因数。

2. 发明授权

US09767552B2 Systems and methods for detecting the presence of anomalous material within tissue 有权
公开(公告)号：US09767552B2
公开(公告)日：2017-09-19
申请号：US14342976
申请日：2012-09-06
申请人： Jon Paul Dobson , Mark Rogers Davidson , Yunmei Chen , Keith David White
发明人： Jon Paul Dobson , Mark Rogers Davidson , Yunmei Chen , Keith David White
IPC分类号： G06T7/00 , G01R33/50 , G01R33/56 , A61B5/00
CPC分类号： G06T7/0012 , A61B5/4088 , G01R33/50 , G01R33/5608 , G06T2200/04 , G06T2207/10088 , G06T2207/20076 , G06T2207/30016
摘要： In one embodiment, the presence of anomalous material within tissue is detected by scanning a patient using magnetic resonance imaging (MRI) to obtain MRI data, identifying individual voxels of the MRI data, identifying multiple parameters of each voxel, and determining as to each voxel based upon the identified parameters the likelihood of tissue represented by the voxel containing anomalous material.

3. 发明申请

US20140219535A1 Systems and Methods for Detecting the Presence of Anomalous Material within Tissue 有权
标题翻译：检测组织中异常物质存在的系统和方法
公开(公告)号：US20140219535A1
公开(公告)日：2014-08-07
申请号：US14342976
申请日：2012-09-06
申请人： Yunmei Chen , Mark Rogers Davidson , Keith David White , Jon Paul Dobson
发明人： Yunmei Chen , Mark Rogers Davidson , Keith David White , Jon Paul Dobson
IPC分类号： G06T7/00 , G01R33/56 , G01R33/50
CPC分类号： G06T7/0012 , A61B5/4088 , G01R33/50 , G01R33/5608 , G06T2200/04 , G06T2207/10088 , G06T2207/20076 , G06T2207/30016
摘要： In one embodiment, the presence of anomalous material within tissue is detected by scanning a patient using magnetic resonance imaging (MRI) to obtain MRI data, identifying individual voxels of the MRI data, identifying multiple parameters of each voxel, and determining as to each voxel based upon the identified parameters the likelihood of tissue represented by the voxel containing anomalous material.
摘要翻译：在一个实施例中，通过使用磁共振成像（MRI）扫描患者来检测组织内异常材料的存在，以获得MRI数据，识别MRI数据的各个体素，识别每个体素的多个参数，以及确定每个体素基于所识别的参数，由含有异常材料的体素表示的组织的可能性。

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