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1. 发明授权

US5422360A Maillard reaction inhibitor 失效
标题翻译：美拉德反应抑制剂
公开(公告)号：US5422360A
公开(公告)日：1995-06-06
申请号：US95994
申请日：1993-07-23
申请人： Keisuke Miyajima , Bonpei Yasui , Masaaki Motoyama , Shintaro Ishikawa , Koichi Yasumura
发明人： Keisuke Miyajima , Bonpei Yasui , Masaaki Motoyama , Shintaro Ishikawa , Koichi Yasumura
IPC分类号： C07D233/88 , C07D233/96 , C07D277/20 , C07D277/54 , C07D487/04 , C07D513/04 , A61K31/415 , C07D233/70
CPC分类号： C07D277/20 , C07D233/88 , C07D233/96 , C07D277/54 , C07D487/04 , C07D513/04
摘要： A novel Maillard reaction inhibitor containing at least one compound represented by formula (1) and the salts thereof; methods for producing the compounds of formula (1) and the salts thereof; a composition for inhibiting the Maillard reaction in living body comprising at least one compound of formula (1) and the salts thereof; and a method for inhibiting the Maillard reaction in living body by administration of a compound of formula (1') or a salt thereof are disclosed.
摘要翻译：一种含有至少一种式（1）表示的化合物及其盐的新颖的美拉德反应抑制剂; 制备式（1）化合物及其盐的方法; 用于抑制活体中美拉德反应的组合物，其包含至少一种式（1）化合物及其盐; 公开了通过给予式（1'）化合物或其盐抑制活体中美拉德反应的方法。

2. 发明授权

US5677322A Maillard reaction inhibitor 失效
标题翻译：美拉德反应抑制剂
公开(公告)号：US5677322A
公开(公告)日：1997-10-14
申请号：US325233
申请日：1994-10-21
申请人： Koichi Yasumura , Keisuke Miyajima , Takao Nagahama , Shintaro Ishikawa , Yuko Nakagawa , Kazuhisa Sugiyama
发明人： Koichi Yasumura , Keisuke Miyajima , Takao Nagahama , Shintaro Ishikawa , Yuko Nakagawa , Kazuhisa Sugiyama
IPC分类号： C07D233/44 , A61K31/415 , A61K31/425 , A61K31/426 , A61K31/44 , A61K31/4427 , A61K31/4433 , A61K31/47 , A61P3/08 , A61P3/10 , A61P43/00 , C07D233/88 , C07D277/20 , C07D277/50 , C07D277/54 , C07D277/82 , C07D401/04 , C07D403/06 , C07D409/04 , C07D409/12 , C07D417/04 , C07D417/06 , C07D417/12 , C07D487/04 , C07D487/08
CPC分类号： C07D403/06 , C07D233/88 , C07D277/50 , C07D277/54 , C07D277/82 , C07D409/12 , C07D417/04 , C07D417/06 , C07D417/12 , C07D487/04
摘要： A compound represented by the following formula is disclosed: ##STR1## wherein the all symbols are defined in the disclosure. A process for producing the compound, and a method for treating diseases caused by a Maillard reaction in living body using the compound are also disclosed.
摘要翻译： PCT No.PCT / JP94 / 00260 Sec。 371日期：1994年10月21日 102（e）日期1994年10月21日PCT 1994年2月21日PCT PCT。第WO94 / 19335号公报 1994年9月1日公开了下列化学式表示的化合物：其中全部符号在本公开内容中定义。还公开了一种制备该化合物的方法以及使用该化合物治疗由生物体中的美拉德反应引起的疾病的方法。

3. 发明授权

US06197774B1 Pyrimidine derivative 失效
标题翻译：嘧啶衍生物
公开(公告)号：US06197774B1
公开(公告)日：2001-03-06
申请号：US09380742
申请日：1999-09-13
申请人： Satoshi Yamada , Naosumi Kinoshita , Koichi Yasumura , Kouji Edamatsu , Takao Nagahama , Shintaro Ishikawa , Takeshi Yamauchi , Kazumasa Kishi , Kazuhisa Sugiyama
发明人： Satoshi Yamada , Naosumi Kinoshita , Koichi Yasumura , Kouji Edamatsu , Takao Nagahama , Shintaro Ishikawa , Takeshi Yamauchi , Kazumasa Kishi , Kazuhisa Sugiyama
IPC分类号： C07D48704
CPC分类号： C07D487/04
摘要： The present invention provides a novel pyrimidine derivative represented by the general formula (1): (wherein R, R4 and R8 are the same as defined in the specification) or pharmaceutically acceptable salt thereof, which possesses an excellent activity for inhibiting the formation of NO (nitrogen oxide) in vivo.
摘要翻译：本发明提供由通式（1）表示的新型嘧啶衍生物（其中R，R 4和R 8与说明书中定义的相同）或其药学上可接受的盐，其具有优异的抑制NO形成的活性（氮氧化物）。

4. 发明授权

US6094265A Calibrator for non-destructive transmission optical measuring apparatus 失效
标题翻译：无损传输光学测量仪的校准器
公开(公告)号：US6094265A
公开(公告)日：2000-07-25
申请号：US311879
申请日：1999-05-14
申请人： Shintaro Ishikawa , Junji Iida , Akira Terashima
发明人： Shintaro Ishikawa , Junji Iida , Akira Terashima
IPC分类号： G01N21/01 , G01N21/27 , G01N21/35 , G01N21/359 , G01N21/59 , G01N33/02
CPC分类号： G01N21/59 , G01N33/025
摘要： In a calibrator used for a non-destructive transmission optical measuring apparatus for quantitatively determining a specific component contained in a measuring object by making light incident on the measuring object at its light-incident area, detecting the light having entered, and having been transmitted through, the interior of the measuring object, at its light-emergent area set at a position different from the light-incident area, and measuring absorption of the light to quantitatively determine the specific component contained in the measuring object, the calibrator comprises a closed body having a light inlet and a light outlet, the interior of which is provided with a substrate having light absorption characteristics identical or similar to those of the specific component, and in which a light path length from the light inlet to the light outlet is so set as to be equal or substantially equal to an effective light path length of the light transmitted through the interior of the measuring object. This calibrator can make calibration on the non-destructive transmission optical measuring apparatus without destroying measuring objects and in a high precision and a good reproducibility and also in a simple way and short time.
摘要翻译：在用于非破坏性透射光学测量装置的校准器中，用于通过使入射到测量对象的光入射区域上的光入射来定量地测定包含在测量对象中的特定成分，检测已经进入并已被传送的光，测量对象的内部，在其出光区域设置在与光入射区域不同的位置，并且测量光的吸收以定量地确定包含在测量对象中的特定部件，校准器包括封闭体具有光入口和光出口，其内部设置有具有与特定部件相同或相似的光吸收特性的基板，并且其中从入光口到光出口的光路长度被设定以等于或基本上等于透射通过内部的光的有效光路长度 e测量对象。该校准器可以对非破坏性透射光学测量装置进行校准，而不会以高精度和良好的再现性，也能以简单的方式和短时间破坏测量对象。

5. 发明授权

US4262454A Workpiece rotational speed controller for cam grinding machine 失效
标题翻译：凸轮磨床工件转速控制器
公开(公告)号：US4262454A
公开(公告)日：1981-04-21
申请号：US44654
申请日：1979-06-01
申请人： Wataru Iida , Toshio Tsujiuchi , Shintaro Ishikawa
发明人： Wataru Iida , Toshio Tsujiuchi , Shintaro Ishikawa
IPC分类号： B24B19/12
CPC分类号： B24B19/125 , Y10T409/305824
摘要： A workpiece rotational speed controller having a pulse counter responsive to a pulse signal generated from a pulse generator for indicating the actual angular position of a cam shaft during grinding on a cam grinding machine and a comparator for comparing a count value of the counter with any one of set values which are set in a plurality of digital switches to designate respective speed change positions. A region detection counter is further provided, which counts any coincidence signal from the comparator so as to enable a command voltage generator to apply to a servomotor for cam shaft drive a command voltage that changes step by step in correspondence to the region detection counter output. This counter output is also applied to a gate circuit, which is thus enabled to selectively apply the set values of the digital switches to the comparator.
摘要翻译：一种工件转速控制器，其具有响应于脉冲发生器产生的脉冲信号的脉冲计数器，用于在凸轮磨床上研磨期间指示凸轮轴的实际角度位置，以及用于将计数器的计数值与任一个设置在多个数字开关中以设定各个变速位置的设定值。进一步提供区域检测计数器，其对来自比较器的任何符合信号进行计数，以便能够使指令电压发生器向伺服马达施加凸轮轴驱动，该指令电压相应于区域检测计数器输出逐步改变。该计数器输出也被施加到门电路，从而能够选择性地将数字开关的设定值应用于比较器。

6. 发明授权

US06504154B2 Non-destructive sugar content measuring apparatus 失效
标题翻译：无损糖含量测定装置
公开(公告)号：US06504154B2
公开(公告)日：2003-01-07
申请号：US09783994
申请日：2001-02-16
申请人： Junji Iida , Akira Terashima , Kazuo Maeda , Shintaro Ishikawa , Shinji Yamauchi
发明人： Junji Iida , Akira Terashima , Kazuo Maeda , Shintaro Ishikawa , Shinji Yamauchi
IPC分类号： G01N2135
CPC分类号： G01N21/3563 , G01N33/025
摘要： A non-destructive sugar content measuring apparatus having a plurality of trays on which vegetables and fruits are to be placed, a transport device for successively delivering the trays at appropriate intervals, and first, second and third measuring sections provided in the course of a transport path and at which laser beams having wavelengths &lgr;1, &lgr;2 and &lgr;3 are respectively made incident on each vegetable or fruit and the amount of light of each laser beam emergent from the vegetable or fruit is measured with a detector provided at each measuring section and the absorbance of each laser beam is determined from the amount of incident light made incident on the vegetable or fruit and the amount of detected light which has been measured with the detector, to measure the sugar content of the vegetables and fruits on the basis of each absorbance.
摘要翻译：一种无损糖测量装置，具有多个托盘，蔬菜和水果放置在其上，用于以适当的间隔连续输送托盘的运送装置以及在运输过程中设置的第一，第二和第三测量部分路径，并且具有波长lambd1，lambd2和lambd3的激光束分别入射到每个蔬菜或水果上，并且用在每个测量部分提供的检测器测量从蔬菜或水果出射的每个激光束的光量，并且吸光度根据入射到植物或果实上的入射光量和用检测器测量的检测光的量来确定每个激光束，以根据每个吸光度测量蔬菜和水果的糖含量。

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