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1. 发明授权

US06258299B1 Device for molding ophthalmic lens material and method of molding therewith 失效
标题翻译：眼镜片材料成型装置及其成型方法
公开(公告)号：US06258299B1
公开(公告)日：2001-07-10
申请号：US09319960
申请日：1999-06-14
申请人： Keiji Yamashita , Tatsuya Ojio , Tohru Kawaguchi
发明人： Keiji Yamashita , Tatsuya Ojio , Tohru Kawaguchi
IPC分类号： B29D1100
CPC分类号： B29C39/24 , B29C39/26 , B29D11/00538 , Y10S425/808
摘要： A device comprises a lower die 6 composed of a lower die base portion and a lower die columnar portion of which tip surface is formed with a lower die molding surface corresponding to one surface of an ocular lens material; an upper die 8 composed of an upper die base portion that is fitted into an upper portion of a hollow hole of the cylindrical main body for parting the hollow hole into two, forming an intermediate chamber 18 between itself and the lower die base portion into which the monomer composition is filled, and forming an exterior accumulating chamber 20 on a side of an upper aperture of the hollow hole into which the monomer composition is accumulated, and an upper die columnar portion of which tip surface is formed with an upper die molding surface corresponding to another surface of the ocular lens material, wherein a molding cavity 22 having a communicating portion 24 is formed between the upper die molding surface and the lower die molding surface; and not less than three piercing holes 16 provided as to pierce the upper die base portion of the upper die in a vertical direction and as to be positioned at equal intervals around the upper die columnar portion. Simplification of the die arrangement of the molding device for molding ocular lens materials through polymerization in a mold can be effectively achieved, and superior transcriptability and uniform lens shape can be realized.
摘要翻译：一个装置包括一个下模6，下模6由一个下模底部和一个下模柱形部分构成，其顶端表面形成有一个对应于眼透镜材料的一个表面的下模成型表面; 上模8由上模底座部分组成，上模底座部分装配到圆筒形主体的中空孔的上部，用于将中空孔分成两部分，在其自身与下模基部之间形成中间室18，单体组合物被填充，并且在聚合有单体组合物的中空孔的上孔的一侧上形成外部积聚室20，并且其顶端表面形成有上模成型表面的上模柱状部分对应于眼透镜材料的另一表面，其中在上模成型表面和下模成型表面之间形成具有连通部分24的模制腔22; 并且不小于三个穿孔16，其设置成在垂直方向上刺穿上模的上模底座部分，并且以相等的间隔设置在上模柱状部分周围。可以有效地实现用于通过模具中的聚合来模制眼镜片材料的模制装置的模具布置的简化，并且可以实现优异的转录性和均匀的透镜形状。

2. 发明授权

US6159242A Intraocular lens having support member fixed in hole formed in insert embedded in lens body, and method of producing the same 失效
标题翻译：具有固定在嵌入在镜体内的插入件中形成的孔中的支撑构件的人工晶状体及其制造方法
公开(公告)号：US6159242A
公开(公告)日：2000-12-12
申请号：US226958
申请日：1999-01-08
申请人： Keiji Yamasita , Tatsuya Ojio , Tohru Kawaguchi
发明人： Keiji Yamasita , Tatsuya Ojio , Tohru Kawaguchi
IPC分类号： A61L27/00 , A61F2/16
CPC分类号： A61F9/0017 , A61F2/16 , A61F2002/1681 , A61F2002/1686
摘要： A method of producing an intraocular lens including a lens body, and at least one support member each of which is inserted into a mounting hole open in a circumferential surface of the lens body, the lens body being obtained by polymerization of a monomer composition in a mold assembly which defines a mold cavity having a profile following that of the lens body, the method comprising the steps of: installing a separately prepared insert member on the mold assembly such that the insert member is located within the mold assembly at a position of the mold cavity corresponding to a region of the lens body where the mounting hole is formed; polymerizing the monomer composition in the mold assembly to provide a workpiece which gives the lens body, such that the workpiece includes the insert member; obtaining the lens body from the workpiece such that at least a portion of the insert member is embedded as an insert in the region of the lens body; and forming the mounting hole in the insert.
摘要翻译：一种制造包括透镜体的人工晶状体的方法，以及至少一个支撑构件，每个支撑构件插入到在透镜体的圆周表面上开口的安装孔中，所述透镜体通过单体组合物在模具组件，其限定具有与透镜主体相似的轮廓的模腔，该方法包括以下步骤：将单独制备的插入构件安装在模具组件上，使得插入构件位于模具组件内的位置处模腔，其与形成有安装孔的透镜体的区域相对应; 在模具组件中聚合单体组合物以提供给予透镜体的工件，使得工件包括插入构件; 从所述工件获得所述透镜体，使得所述插入构件的至少一部分作为插入件嵌入所述透镜体的区域中; 以及在所述插入件中形成所述安装孔。

3. 发明授权

US6140438A Soft intraocular lens material 有权
标题翻译：软性眼内透镜材料
公开(公告)号：US6140438A
公开(公告)日：2000-10-31
申请号：US132055
申请日：1998-08-11
申请人： Tatsuya Ojio , Kazuharu Niwa , Tohru Kawaguchi
发明人： Tatsuya Ojio , Kazuharu Niwa , Tohru Kawaguchi
IPC分类号： G02C7/04 , A61L27/00 , A61L27/16 , A61L27/50 , C08F20/28 , C08F20/56 , C08F26/06 , C08F226/10
CPC分类号： A61L27/50 , A61F2/16 , A61L27/16 , A61L2430/16
摘要： A soft intraocular lens material which consists essentially of a polymer obtained by polymerizing polymerizable components containing a hydrophilic monomer, and which has a water absorptivity of from 1.5 to 4.5 wt %.
摘要翻译：一种软性眼内透镜材料，其基本上由通过聚合含有亲水性单体的可聚合组分获得的聚合物组成，并且其吸水率为1.5至4.5重量％。

4. 发明授权

US06326448B1 Soft intraocular lens material 有权
标题翻译：软性眼内透镜材料
公开(公告)号：US06326448B1
公开(公告)日：2001-12-04
申请号：US09252222
申请日：1999-02-18
申请人： Tatsuya Ojio , Kazuharu Niwa , Tohru Kawaguchi
发明人： Tatsuya Ojio , Kazuharu Niwa , Tohru Kawaguchi
IPC分类号： C08F12606
CPC分类号： A61L27/50 , A61L27/16 , A61L2430/16 , C08L39/06 , C08L33/06 , C08L33/26 , C08L33/14
摘要： A soft intraocular lens material which consists essentially of a polymer obtained by polymerizing polymerizable components containing a hydrophilic monomer, and which has a water absorptivity of from 1.5 to 4.5 wt %.
摘要翻译：一种软性眼内透镜材料，其基本上由通过聚合含有亲水性单体的可聚合组分获得的聚合物组成，并且其吸水率为1.5至4.5重量％。

5. 发明授权

US06355190B1 Method of molding ophthalmic lens product, and mold assembly used in the method 失效
标题翻译：眼镜镜片产品的成型方法以及该方法中使用的模具组装
公开(公告)号：US06355190B1
公开(公告)日：2002-03-12
申请号：US09333401
申请日：1999-06-15
申请人： Tatsuya Ojio , Kazuharu Niwa , Keiji Yamashita , Akihiro Yasuda
发明人： Tatsuya Ojio , Kazuharu Niwa , Keiji Yamashita , Akihiro Yasuda
IPC分类号： B29D1100
CPC分类号： B29C31/04 , B29C33/0061 , B29C39/24 , B29C2043/3618 , B29D11/00317 , B29D11/00432 , B29D11/023 , B29K2105/0002 , B29L2011/0041 , Y10S425/808
摘要： A method of molding an ophthalmic lens product by using a mold assembly which has a mold cavity, the lens product having a configuration corresponding to that of an ophthalmic lens or a precursor of the ophthalmic lens and being obtained by polymerizing a liquid monomer composition in the mold cavity to provide a polymer product which gives the lens product, the method comprising the steps of: preparing the mold assembly having a monomer storage space for storing the liquid monomer composition, which storage space is held in fluid communication with the mold cavity; filling the mold cavity of the mold assembly with the liquid monomer composition while the liquid monomer composition is accommodated in the monomer storage space; and polymerizing the liquid monomer composition at a temperature of 10-80° C. while a pressure higher than the atmospheric pressure is applied directly to a liquid surface of a mass of the liquid monomer composition accommodated in the monomer storage space.
摘要翻译：一种通过使用具有模具腔的模具组件来模制眼用透镜产品的方法，所述透镜产品具有与眼科镜片或眼科镜片的前体相对应的构造，并且通过使液体单体组合物在模腔以提供给予透镜产品的聚合物产品，该方法包括以下步骤：制备具有用于储存液体单体组合物的单体储存空间的模具组件，该储存空间保持与模腔流体连通; 当液体单体组合物容纳在单体储存空间中时，用液体单体组合物填充模具组件的模腔; 并在10-80℃的温度下使液体单体组合物聚合，同时将高于大气压的压力直接施加到容纳在单体储存空间中的液体单体组合物的液体表面。

6. 发明授权

US06277940B1 Material for a soft intraocular lens 有权
标题翻译：软眼内镜的材质
公开(公告)号：US06277940B1
公开(公告)日：2001-08-21
申请号：US09248265
申请日：1999-02-11
申请人： Kazuharu Niwa , Tatsuya Ojio , Toru Kawaguchi
发明人： Kazuharu Niwa , Tatsuya Ojio , Toru Kawaguchi
IPC分类号： C08F22026
CPC分类号： A61L27/16 , A61L2430/16 , C08F2220/281 , C08L33/14 , C08F2220/302 , C08F2220/1808 , C08F222/1006 , C08F220/14 , C08F2222/1013
摘要： There is provided a material for a soft intraocular lens, which has excellent transparency and flexibility, can be inserted from a small incision and has an high refractive index independent on a water content. The material comprises (A) 5-25 % by weight of acrylate containing an aromatic ring, (B) 50-90 % by weight of 2-hydroxyethyl (meth)acrylate, and (C) 5-45 % by weight of a (meth)acrylate monomer having the coefficient of water absorption of the homopolymer thereof of not more than 30 % by weight, except for (A) acrylate containing an aromatic ring and (B) 2-hydroxyethyl (meth)acrylate.
摘要翻译：提供了一种用于柔软的眼内透镜的材料，其具有优异的透明性和柔性，可以从小切口插入并且具有与水含量无关的高折射率。该材料包含（A）5-25重量％的含有芳环的丙烯酸酯，（B）50-90重量％的（甲基）丙烯酸2-羟乙酯，和（C）5-45重量％的（甲基）（A）含有芳环的丙烯酸酯和（B）（甲基）丙烯酸2-羟基乙酯以外，其均聚物的吸水系数为30重量％以下的甲基丙烯酸酯单体。

7. 发明授权

US06320008B2 Polymeric colorant and colored material for ocular lens using the colorant 有权
标题翻译：使用着色剂的聚合物着色剂和用于眼镜片的着色材料
公开(公告)号：US06320008B2
公开(公告)日：2001-11-20
申请号：US09836906
申请日：2001-04-17
申请人： Akira Tsuzuki , Kazuharu Niwa , Tatsuya Ojio
发明人： Akira Tsuzuki , Kazuharu Niwa , Tatsuya Ojio
IPC分类号： C08F12600
CPC分类号： A61L27/50 , A61L2430/16 , C08F220/14 , C08F220/30 , C08F220/34 , G02B1/043
摘要： A polymeric colorant represented by the following formula: A1—N═N—A2—O—(CH2)n-X wherein, A1 represents an aryl group which may have a substituent group, A2 represents an arylene group which may have a substituent group, X represents one of an acryloyloxy group, a methacryloyloxy group, a vinylphenyl group, a vinylphenyloxy group, and a vinylphenylalkyloxy group whose alkyl portion has 1-5 carbon atoms, and n is an integer of 1-5, and a colored material for an ocular lens which uses to the polymeric colorant is also disclosed.
摘要翻译：由下式表示的聚合物着色剂：其中，A 1表示可以具有取代基的芳基，A 2表示可以具有取代基的亚芳基，X表示丙烯酰氧基，甲基丙烯酰氧基，乙烯基苯基，乙烯基苯氧基和烷基部分具有1-5个碳原子的乙烯基苯基烷氧基，n为1-5的整数，并且还公开了用于该聚合物着色剂的用于眼用透镜的着色材料。

8. 发明授权

US06242551B1 Polymeric colorant and colored material for ocular lens using the colorant 有权
标题翻译：使用着色剂的聚合物着色剂和用于眼镜片的着色材料
公开(公告)号：US06242551B1
公开(公告)日：2001-06-05
申请号：US09251377
申请日：1999-02-17
申请人： Akira Tsuzuki , Kazuharu Niwa , Tatsuya Ojio
发明人： Akira Tsuzuki , Kazuharu Niwa , Tatsuya Ojio
IPC分类号： C08F12600
CPC分类号： D06P1/006 , C08F246/00 , C09B69/106 , D06P1/0052 , G02B1/043 , C08L33/04
摘要： A polymeric colorant represented by the following formula: A1—N═N—A2—O—(CH2)n—X wherein, A1 represents an aryl group which may have a substituent group, A2 represents an arylene group which may have a substituent group, X represents one of an acryloyloxy group, a methacryloyloxy group, a vinylphenyl group, a vinylphenyloxy group, and a vinylphenylalkyloxy group whose alkyl portion has 1-5 carbon atoms, and n is an integer of 1-5, and a colored material for an ocular lens which uses the polymeric colorant is also disclosed.
摘要翻译：由下式表示的聚合物着色剂：其中，A 1表示可以具有取代基的芳基，A 2表示可以具有取代基的亚芳基，X表示丙烯酰氧基，甲基丙烯酰氧基，乙烯基苯基，乙烯基苯氧基和烷基部分具有1-5个碳原子的乙烯基苯基烷氧基，n是1-5的整数，并且还公开了使用该聚合物着色剂的用于眼透镜的着色材料。

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