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1. 发明申请

US20160184356A1 ARSENIC-BASED TREATMENT OF CANCERS AND INFLAMMATORY DISORDERS 审中-公开
标题翻译：基于ARSENIC的癌症治疗和炎症性疾病
公开(公告)号：US20160184356A1
公开(公告)日：2016-06-30
申请号：US14776929
申请日：2014-03-14
申请人： Ke Jian Jim LIU , Laurie HUDSON , Karen COOPER , Xixi ZHOU , STC.UNM
发明人： Ke Jian Jim Liu , Laurie Hudson , Karen Cooper , Xixi Zhou
IPC分类号： A61K33/36 , A61K45/06 , A61K41/00
CPC分类号： A61K33/36 , A61K31/166 , A61K31/407 , A61K31/4184 , A61K31/4188 , A61K31/454 , A61K31/502 , A61K31/5025 , A61K31/55 , A61K31/555 , A61K31/7068 , A61K41/0038 , A61K45/06 , A61N2005/1098 , A61K2300/00
摘要： In one embodiment, the invention provides a method of treating a subject who suffers from a cancer (particularly a chemotherapeutic or radiotherapeutic-resistant cancer) or from an inflammatory disorder, the method comprising co-administering to the subject a pharmaceutically-effective amount of: (a) one or more elements or compounds selected from the group consisting of arsenic, an arsenite and arsenic trioxide (ATO); and optionally (b) at least one anticancer agent (preferably a DNA damaging agent); and/or (c) at least one or more Poly(ADP-ribose) polymerase (PARP) inhibitors other than arsenic, an arsenite and arsenic trioxide (ATO). In preferred embodiments, the arsenic for the treatment of cancer, arsenite and ATO serve as radio sensitizers for concomitant radiotherapy as well as PARP inhibitors. Methods for treating inflammatory disease are also disclosed. Related pharmaceutical formulations are also provided.
摘要翻译：在一个实施方案中，本发明提供了治疗患有癌症（特别是化学治疗或放射治疗耐药性癌症）或炎症性疾病的受试者的方法，所述方法包括向受试者共同施用药物有效量的：（a）选自砷，亚砷酸钠和三氧化二砷（ATO）中的一种或多种元素或化合物; 和（b）至少一种抗癌剂（优选DNA损伤剂）; 和/或（c）至少一种或多种除砷以外的聚（ADP-核糖）聚合酶（PARP）抑制剂，亚砷酸钠和三氧化二砷（ATO））。在优选实施方案中，用于治疗癌症，亚砷酸盐和ATO的砷用作伴随放射治疗的放射敏化剂以及PARP抑制剂。还公开了治疗炎性疾病的方法。还提供了相关的药物制剂。

2. 发明申请

US20100121299A1 WRAPPING PACKAGE 审中-公开
标题翻译：包装包装
公开(公告)号：US20100121299A1
公开(公告)日：2010-05-13
申请号：US12511293
申请日：2009-07-29
申请人： Karen Cooper
发明人： Karen Cooper
IPC分类号： A61F13/551 , A61F13/20
CPC分类号： A61F13/5518 , A61F13/5519 , A61F15/003
摘要： A wrapping package for storing one or more unused articles such as a new tampon, and one or more used articles such as a used tampon, includes a base member, a flap member, and a covering member. The base member includes a first section, a second section, and a middle section configured in between the first section and the second section. An end portion of the flap member is capable of being resealably coupled with the first section for configuring a first enclosure, which is capable of storing the one or more unused articles. The covering member is coupled with the second section of the base member for configuring a second enclosure, which is capable of receiving the one or more used articles. Further disclosed is a method of accessing the one or more unused articles and disposing the one or more used articles.
摘要翻译：一种用于储存一个或多个未使用的物品（例如新棉条）和一个或多个使用过的制品（例如使用过的棉条）的包装包装件包括基底构件，折板构件和覆盖构件。基部构件包括构造在第一部分和第二部分之间的第一部分，第二部分和中间部分。挡板构件的端部能够与第一部分可重新密封地联接，用于构造能够存储一个或多个未使用的物品的第一外壳。覆盖部件与基部部件的第二部分连接，用于构造能够接收一个或多个废弃物品的第二外壳。进一步披露的是访问一个或多个未使用的物品并布置一个或多个废弃物品的方法。

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