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1. 发明申请

US20050124985A1 Laser induced liquid jet generatng apparatus 有权
标题翻译：激光诱导液体喷射发生装置
公开(公告)号：US20050124985A1
公开(公告)日：2005-06-09
申请号：US10989406
申请日：2004-11-17
申请人： Kazuyoshi Takayama , Takayuki Hirano , Atsuhiro Nakagawa , Hideshi Obitsu , Shigeru Omori , Takeshi Kanamaru
发明人： Kazuyoshi Takayama , Takayuki Hirano , Atsuhiro Nakagawa , Hideshi Obitsu , Shigeru Omori , Takeshi Kanamaru
IPC分类号： A61B17/32 , A61B18/26 , A61B18/18
CPC分类号： A61B18/26 , A61B17/3203 , A61B17/32037 , A61B2017/32032 , A61B2018/263
摘要： The laser induced liquid jet generating apparatus irradiates a laser beam on a liquid in a main body, guides the generated liquid jet into a catheter via a nozzle, and generates a flow in the direction opposite the liquid jet. Even by the use of a catheter having a small outside diameter, therefore, the apparatus is enabled to effect powerful laser irradiation without being thermally affected by the laser beam and consequently shatter thrombus, for example, and recover by aspiration the shattered thrombus through the distal end of the catheter.
摘要翻译：激光感应液体喷射发生装置将激光束照射在主体中的液体上，经由喷嘴将生成的液体射流引导到导管中，并且沿与液体射流相反的方向产生流动。因此，即使通过使用具有小外径的导管，该装置能够实现强大的激光照射，而不受激光束的热影响，从而例如破坏血栓，并且通过将破裂的血栓抽吸通过远端导管末端。

2. 发明授权

US07740626B2 Laser induced liquid jet generating apparatus 有权
标题翻译：激光诱导液体喷射发生装置
公开(公告)号：US07740626B2
公开(公告)日：2010-06-22
申请号：US10989406
申请日：2004-11-17
申请人： Kazuyoshi Takayama , Takayuki Hirano , Atsuhiro Nakagawa , Hideshi Obitsu , Shigeru Omori , Takeshi Kanamaru
发明人： Kazuyoshi Takayama , Takayuki Hirano , Atsuhiro Nakagawa , Hideshi Obitsu , Shigeru Omori , Takeshi Kanamaru
IPC分类号： A61B18/20
CPC分类号： A61B18/26 , A61B17/3203 , A61B17/32037 , A61B2017/32032 , A61B2018/263
摘要： The laser induced liquid jet generating apparatus irradiates a laser beam on a liquid in a main body, guides the generated liquid jet into a catheter via a nozzle, and generates a flow in the direction opposite the liquid jet. Even by the use of a catheter having a small outside diameter, therefore, the apparatus is enabled to effect powerful laser irradiation without being thermally affected by the laser beam and consequently shatter thrombus, for example, and recover by aspiration the shattered thrombus through the distal end of the catheter.
摘要翻译：激光感应液体喷射发生装置将激光束照射在主体中的液体上，经由喷嘴将生成的液体射流引导到导管中，并且沿与液体射流相反的方向产生流动。因此，即使通过使用具有小外径的导管，该装置能够实现强大的激光照射，而不受激光束的热影响，从而例如破坏血栓，并且通过将破裂的血栓抽吸通过远端导管末端。

3. 发明申请

US20060064114A1 Wire to remove intravascular foreign body and medical instrument 审中-公开
标题翻译：电线去除血管内异物和医疗器械
公开(公告)号：US20060064114A1
公开(公告)日：2006-03-23
申请号：US11232021
申请日：2005-09-22
申请人： Hideshi Obitsu , Takeshi Kanamaru
发明人： Hideshi Obitsu , Takeshi Kanamaru
IPC分类号： A61B17/26
CPC分类号： A61B17/221 , A61B2017/00398 , A61B2017/00867 , A61B2017/2212
摘要： A wire to remove an intravascular foreign body includes a flexible long wire body, a foreign body capturing portion to capture a foreign body in a vessel, and an operating wire to deform the foreign body capturing portion. The foreign body capturing portion includes a first capturing part and a second capturing part. The first capturing part is formed from a filament which assumes a helical shape in its natural state and is arranged on the forward end of the wire body. The second capturing part is formed from a filament which assumes a helical shape in its natural state and is arranged on the forward end of the first capturing part. The first and second capturing parts together form a rearwardly open space for capturing the foreign body when the wire is moved rearwardly relative to the foreign body. The second capturing part is deformable such that the distance between its adjacent filaments decreases upon operation of the operating wire. The wire is capable of surely capturing and removing a foreign body in the vessel.
摘要翻译：用于去除血管内异物的线包括柔性长线体，捕获血管中的异物的异物捕获部分和使异物捕获部分变形的操作线。异物捕获部分包括第一捕获部分和第二捕获部分。第一捕获部分由长丝形成，该细丝处于其天然状态的螺旋形状并且布置在线体的前端。第二捕获部分由其自然状态呈螺旋状的细丝形成，并布置在第一捕获部分的前端。当线相对于异物向后移动时，第一和第二捕获部分一起形成用于捕获异物的向后开放的空间。第二捕获部分是可变形的，使得它的相邻细丝之间的距离在操作线的操作时减小。电线能够可靠地捕获和除去容器中的异物。

4. 发明授权

US08303612B2 Intravascular foreign matter removing wire and medical implement 有权
标题翻译：血管外异物去除电线和医疗器具
公开(公告)号：US08303612B2
公开(公告)日：2012-11-06
申请号：US11921935
申请日：2006-06-07
申请人： Koji Nakao , Hideshi Obitsu , Takeshi Kanamaru
发明人： Koji Nakao , Hideshi Obitsu , Takeshi Kanamaru
IPC分类号： A61B17/22
CPC分类号： A61B17/221 , A61B2017/22034 , A61B2017/2212
摘要： An intravascular foreign matter removing wire has a flexible long wire body, a first catching section located on the tip side of the wire body and operative to catch a foreign matter present inside a blood vessel, and a second catching section located in the vicinity of and on the base end side of the first catching section and operative to catch a foreign matter present inside a blood vessel.
摘要翻译：血管内异物去除线具有柔性长线体，位于线体的末端侧的第一捕获部，并且可操作以捕获存在于血管内的异物，以及第二捕获部，其位于在第一捕捉部分的基端侧，并且用于捕获存在于血管内的异物。

5. 发明申请

US20060293697A1 Wire for removing an intravascular foreign body and medical instrument 审中-公开
标题翻译：用于去除血管内异物和医疗器械的电线
公开(公告)号：US20060293697A1
公开(公告)日：2006-12-28
申请号：US11455794
申请日：2006-06-20
申请人： Koji Nakao , Hideshi Obitsu , Takeshi Kanamaru
发明人： Koji Nakao , Hideshi Obitsu , Takeshi Kanamaru
IPC分类号： A61B17/22
CPC分类号： A61B17/221 , A61B2017/22035 , A61B2017/2212
摘要： A wire for removing an intravascular foreign body according to the present invention is a wire for removing an intravascular foreign body, including: a long or elongated wire body with flexibility; and a capturing portion including a foreign body capturing space which captures a foreign body in a blood vessel therein, the capturing portion being provided on a distal end of the wire body, in which the capturing portion includes: at least two branch wires branching from the distal end of the wire body; and a plurality of filaments bridged between the two branch wires, and at least one of the filaments includes a plurality of curved projections bent in a direction deviated from an extension line of a central axis of a proximal end of the filament. In accordance with the wire for removing an intravascular foreign body according to the present invention, the foreign body in the blood vessel can be surely captured and removed.
摘要翻译：根据本发明的用于去除血管内异物的线是用于去除血管内异物的线，包括：具有柔性的长或细长的线体; 以及捕获部，其包括捕获其中的血管中的异物的异物捕获空间，所述捕获部设置在所述线体的远端，所述捕获部包括：至少两根分支线，线体的末端; 以及桥接在两个分支线之间的多个细丝，并且所述长丝中的至少一个包括多个弯曲突起，所述多个弯曲突起沿与灯丝的近端的中心轴线的延伸线偏离的方向弯曲。根据本发明的用于除去血管内异物的线，可以可靠地捕获和除去血管中的异物。

6. 发明申请

US20100016875A1 Intravascular foreign matter removing wire and medical implement 有权
标题翻译：血管外异物去除电线和医疗器具
公开(公告)号：US20100016875A1
公开(公告)日：2010-01-21
申请号：US11921935
申请日：2006-06-07
申请人： Koji Nakao , Hideshi Obitsu , Takeshi Kanamaru
发明人： Koji Nakao , Hideshi Obitsu , Takeshi Kanamaru
IPC分类号： A61B17/22
CPC分类号： A61B17/221 , A61B2017/22034 , A61B2017/2212
摘要： An intravascular foreign matter removing wire has a flexible long wire body, a first catching section located on the tip side of the wire body and operative to catch a foreign matter present inside a blood vessel, and a second catching section located in the vicinity of and on the base end side of the first catching section and operative to catch a foreign matter present inside a blood vessel.
摘要翻译：血管内异物去除线具有柔性长线体，位于线体的末端侧的第一捕获部，并且可操作以捕获存在于血管内的异物，以及第二捕获部，其位于在第一捕捉部分的基端侧，并且用于捕获存在于血管内的异物。

7. 发明授权

US07041116B2 Intravascular obstruction removing wire and medical instrument 有权
公开(公告)号：US07041116B2
公开(公告)日：2006-05-09
申请号：US10185067
申请日：2002-07-01
申请人： Katsuya Goto , Takashi Kaneko , Takeshi Kanamaru , Masahiro Takeuchi , Keiji Okada
发明人： Katsuya Goto , Takashi Kaneko , Takeshi Kanamaru , Masahiro Takeuchi , Keiji Okada
IPC分类号： A61M29/00
CPC分类号： A61B17/221 , A61B2017/2212
摘要： An intravascular obstruction removing wire includes an elongate wire body, at least two non-branched wire portions having distal ends and proximal ends which are connected to a distal end of the wire main body, and a plurality of filament portions extending across the wire portions. The non-branched wire portions and the filament portions form a trapping portion. The trapping portion is deformable from a large-diameter state in which the non-branched portions branch to the distal end of the wire body forward in different directions and the filament portions are separated from each other, so that a space surrounded by the non-branched wire portions and the filament portions is formed to trap therein an obstruction in a blood vessel, to a small-diameter state in which the non-branched wire portions are positioned so that a distance between the wire portions is smaller than that of the wire portions in the large-diameter state.

8. 发明授权

US07753919B2 Wire for removing intravascular foreign body and medical instrument 有权
标题翻译：电线去除血管内异物和医疗器械
公开(公告)号：US07753919B2
公开(公告)日：2010-07-13
申请号：US11219876
申请日：2005-09-07
申请人： Takeshi Kanamaru
发明人： Takeshi Kanamaru
IPC分类号： A61B17/24 , A61B17/26 , A61M29/00
CPC分类号： A61B17/22 , A61B17/221 , A61B2017/2212 , A61B2017/2215
摘要： A wire for removing an intravascular foreign body comprises a flexible wire body, a branch part branching out from the forward end of the wire body, and a plurality of filaments extending across the branch part. The branch part and the filaments form a space for capturing a foreign body therein. At least one of the filaments is changeable in length so that the loop formed by the filament and the branch part changes in size. The wire is capable of relatively reliably capturing and removing a foreign body in the vessel.
摘要翻译：用于去除血管内异物的线包括柔性线体，从线体的前端分支的分支部分和跨越分支部分延伸的多根细丝。分支部分和长丝形成用于捕获异物的空间。长丝中的至少一根长度是可变的，使得由灯丝和分支部分形成的环尺寸变化。导线能够相对可靠地捕获和移除容器中的异物。

9. 发明申请

US20060052862A1 Intravascular, indwelling instrument 审中-公开
标题翻译：血管内，留置仪器
公开(公告)号：US20060052862A1
公开(公告)日：2006-03-09
申请号：US11217452
申请日：2005-09-02
申请人： Takeshi Kanamaru , Yotaro Fujita
发明人： Takeshi Kanamaru , Yotaro Fujita
IPC分类号： A61F2/82
CPC分类号： A61L31/047 , A61L2430/36
摘要： An intravascular, indwelling instrument for placement in a blood vessel includes a body having a face in contact with a maintained blood flow to be maintained and a face in contact with a non-maintained blood flow not to be maintained, and a peptide fixed to all or part of the maintained blood flow contact face or the non-maintained blood flow contact face of the body. The peptide has specific interaction with vascular endothelial precursor cells, with the peptide permitting selective adsorption and adhesion of the vascular endothelial precursor cells to cover all or part of the maintained blood flow contact face or the non-maintained blood flow contact face of the body with the vascular endothelial precursor cells thereby reducing or inhibiting the blood flow not to be maintained.
摘要翻译：用于放置在血管中的血管内留置器械包括：身体，其具有与要维持的保持的血流接触的面和与不保持的未保持的血流接触的面，以及固定到所有的血液的肽或身体的维持的血液流动接触面或未维持的血液流动接触面的一部分。肽与血管内皮前体细胞具有特异性相互作用，其中肽允许血管内皮前体细胞的选择性吸附和粘附以覆盖身体的所有或部分维持的血液接触面或未维持的血液流动接触面，血管内皮前体细胞由此减少或抑制血流不被维持。

10. 发明授权

US07575585B2 Intravascular obstruction removing wire and medical instrument 有权
标题翻译：血管内阻塞去除电线和医疗器械
公开(公告)号：US07575585B2
公开(公告)日：2009-08-18
申请号：US11281358
申请日：2005-11-18
申请人： Katsuya Goto , Takashi Kaneko , Takeshi Kanamaru , Masahiro Takeuchi , Keiji Okada
发明人： Katsuya Goto , Takashi Kaneko , Takeshi Kanamaru , Masahiro Takeuchi , Keiji Okada
IPC分类号： A61M29/00 , A61B17/221
CPC分类号： A61B17/221 , A61B2017/2212
摘要： An intravascular obstruction removing wire includes an elongate wire body, at least two non-branched wire portions having distal ends and proximal ends which are connected to a distal end of the wire main body, and a plurality of filament portions extending across the wire portions. The non-branched wire portions and the filament portions form a trapping portion. The trapping portion is deformable from a large-diameter state in which the non-branched portions branch to the distal end of the wire body forward in different directions and the filament portions are separated from each other, so that a space surrounded by the non-branched wire portions and the filament portions is formed to trap therein an obstruction in a blood vessel, to a small-diameter state in which the non-branched wire portions are positioned so that a distance between the wire portions is smaller than that of the wire portions in the large-diameter state.
摘要翻译：血管内梗阻去除线包括细长线体，至少两个非分支线部分，其具有连接到线主体的远端的远端和近端，以及延伸穿过线部分的多个细丝部分。非分支线部分和细丝部分形成捕获部分。捕获部从大直径状态变形，其中非分支部分向线体的远端分支到不同方向的前端，并且细丝部分彼此分离，分支线部分和细丝部分形成为将血管中的梗阻捕获到非分支线部分定位的小直径状态，使得线部分之间的距离小于线的距离大直径状态的部分。

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