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    • 7. 发明授权
    • Analyzer
    • 分析仪
    • US07955556B2
    • 2011-06-07
    • US11062933
    • 2005-02-23
    • Hiroki KoikeMasayuki Ikeda
    • Hiroki KoikeMasayuki Ikeda
    • G01N21/00
    • G01N35/04G01N35/0095Y10T436/113332Y10T436/114165
    • An analyzer capable of operating in a normal processing mode performing sequential analysis of a plurality of specimens and in an interrupting mode performing analysis of an urgent specimen that comprising a suction unit for suctioning an urgent specimen, an analysis unit for analyzing an urgent specimen suctioned by the suction unit, an urgent specimen container holder for holding an urgent specimen container containing an urgent specimen, and a moving mechanism for moving the urgent specimen container holder between a placement position at which an urgent specimen container is placed in the holder, and a suction position at which an urgent specimen is suctioned from an urgent specimen container, wherein the moving mechanism comprises a movement force supplying mechanism for supplying a force to move the urgent specimen container holder from the suction position to the placement position is disclosed.
    • 一种能够以正常处理模式操作的分析器,对多个样本进行顺序分析,并且执行对包括用于抽吸紧急样本的抽吸单元的紧急样本进行分析的中断模式,分析单元,用于分析由 抽吸单元,用于容纳装有紧急样本的紧急样本容器的紧急检体容器保持器和用于使紧急检体容器保持件在紧固检体容器被放置在保持器中的位置与吸引口之间移动的移动机构 公开了一种紧急样本从紧急样本容器抽吸的位置,其中移动机构包括用于提供将紧急样本容器保持器从抽吸位置移动到放置位置的力的移动力供给机构。
    • 8. 发明申请
    • Analyzer
    • 分析仪
    • US20050186113A1
    • 2005-08-25
    • US11062933
    • 2005-02-23
    • Hiroki KoikeMasayuki Ikeda
    • Hiroki KoikeMasayuki Ikeda
    • G01N35/02G01N35/00G01N35/04
    • G01N35/04G01N35/0095Y10T436/113332Y10T436/114165
    • An analyzer capable of operating in a normal processing mode performing sequential analysis of a plurality of specimens and in an interrupting mode performing analysis of an urgent specimen that comprising a suction unit for suctioning an urgent specimen, an analysis unit for analyzing an urgent specimen suctioned by the suction unit, an urgent specimen container holder for holding an urgent specimen container containing an urgent specimen, and a moving mechanism for moving the urgent specimen container holder between a placement position at which an urgent specimen container is placed in the holder, and a suction position at which an urgent specimen is suctioned from an urgent specimen container, wherein the moving mechanism comprises a movement force supplying mechanism for supplying a force to move the urgent specimen container holder from the suction position to the placement position is disclosed.
    • 一种能够以正常处理模式操作的分析器,对多个样本进行顺序分析,并且执行对包括用于抽吸紧急样本的抽吸单元的紧急样本进行分析的中断模式,分析单元,用于分析由 抽吸单元,用于容纳装有紧急样本的紧急样本容器的紧急检体容器保持器和用于使紧急检体容器保持件在紧固检体容器被放置在保持器中的位置与吸引口之间移动的移动机构 公开了一种紧急样本从紧急样本容器抽吸的位置,其中移动机构包括用于提供将紧急样本容器保持器从抽吸位置移动到放置位置的力的移动力供给机构。
    • 9. 发明授权
    • Chromane substituted benzimidazole derivatives
    • 苯并二氢苯并咪唑衍生物
    • US07723321B2
    • 2010-05-25
    • US11612583
    • 2006-12-19
    • Takeshi HanazawaHiroki Koike
    • Takeshi HanazawaHiroki Koike
    • A61K31/4184C07D405/02C07D407/02
    • C07D405/12C07D409/12
    • This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: A, B, X, R1, R2, R3, R4, R5, R6, R7 and R8 are each as described herein or a pharmaceutically acceptable salt, and compositions containing such compounds and the use of such compounds in the treatment of a condition mediated by acid pump antagonistic activity such as, but not limited to, as gastrointestinal disease, gastroesophageal disease, gastroesophageal reflux disease (GERD), peptic ulcer, gastric ulcer, duodenal ulcer, NSAID-induced ulcers, gastritis, infection of Helicobacter pylori, dyspepsia, functional dyspepsia, Zollinger-Ellison syndrome, non-erosive reflux disease (NERD), visceral pain, heartburn, nausea, esophagitis, dysphagia, hypersalivation, airway disorders or asthma.
    • 本发明涉及式(I)化合物或其药学上可接受的盐,其中:A,B,X,R 1,R 2,R 3,R 4,R 5,R 6,R 7和R 8各自如本文所述, 可接受的盐和含有这些化合物的组合物,以及这些化合物在治疗由酸泵拮抗活性(例如但不限于胃肠疾病,胃食管疾病,胃食管反流病(GERD)),消化性溃疡 ,胃溃疡,十二指肠溃疡,NSAID诱发的溃疡,胃炎,幽门螺杆菌感染,消化不良,功能性消化不良,佐林格 - 埃利森综合征,非侵蚀性反流病(NERD),内脏痛,胃灼热,恶心,食管炎,吞咽困难,过度激素 ,气道障碍或哮喘。
    • 10. 发明授权
    • Chromane substituted benzimidazole derivatives as acid pump antagonists
    • 色烷取代的苯并咪唑衍生物作为酸泵拮抗剂
    • US07718809B2
    • 2010-05-18
    • US11916671
    • 2006-06-02
    • Hiroki KoikeSachiko Sakakibara
    • Hiroki KoikeSachiko Sakakibara
    • A61K31/4184C07D405/12
    • C07D405/12C07D405/14
    • This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: A, B, X, R1, R2, R3, R4, R5 and R6, R7, R8 and R9 are each as described herein or a pharmaceutically acceptable salt, and compositions containing such compounds and the use of such compounds in the treatment of a condition mediated by acid pump antagonistic activity such as, but not limited to, as gastrointestinal disease, gastroesophageal disease, gastroesophageal reflux disease (GERD), peptic ulcer, gastric ulcer, duodenal ulcer, NSAID-induced ulcers, gastritis, infection of Helicobacter pylori, dyspepsia, functional dyspepsia, Zollinger-Ellison syndrome, non-erosive reflux disease (NERD), visceral pain, heartburn, nausea, esophagitis, dysphagia, hypersalivation, airway disorders or asthma.
    • 本发明涉及式(I)化合物或其药学上可接受的盐,其中:A,B,X,R 1,R 2,R 3,R 4,R 5和R 6,R 7,R 8和R 9各自如本文所述或 药学上可接受的盐,以及含有这些化合物的组合物,以及这些化合物在治疗由酸泵拮抗活性介导的病症中的用途,例如但不限于胃肠道疾病,胃食管疾病,胃食管反流病(GERD), 消化性溃疡,胃溃疡,十二指肠溃疡,NSAID诱导的溃疡,胃炎,幽门螺杆菌感染,消化不良,功能性消化不良,佐林格 - 埃里森综合征,非侵蚀性反流疾病(NERD),内脏痛,胃灼热,恶心,食管炎,吞咽困难 ,过度激活,气道障碍或哮喘。