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1. 发明授权

US06383040B2 Jet propulsion system for watercraft 有权
标题翻译：喷气推进系统
公开(公告)号：US06383040B2
公开(公告)日：2002-05-07
申请号：US09682031
申请日：2001-07-12
申请人： Kazumasa Ito , Tetsuya Ishino , Chihiro Matsumoto
发明人： Kazumasa Ito , Tetsuya Ishino , Chihiro Matsumoto
IPC分类号： B63H1100
CPC分类号： B63H11/08
摘要： A jet propelled watercraft having an improved extension assembly for dampening pulsations from the impeller of the jet propulsion unit and also for mounting the jet propulsion unit. The structure simplifies the overall assembly and permits individual tuning with conventional units.
摘要翻译：一种具有改进的延伸组件的喷射推进的船舶，用于衰减来自喷射推进单元的叶轮的脉动，并且还用于安装喷气推进单元。该结构简化了整体组装，并允许使用常规单元进行单独调谐。

2. 发明授权

US06431925B1 Jet propulsion system for watercraft 有权
标题翻译：喷气推进系统
公开(公告)号：US06431925B1
公开(公告)日：2002-08-13
申请号：US09630668
申请日：2000-08-02
申请人： Kazumasa Ito , Tetsuya Ishino
发明人： Kazumasa Ito , Tetsuya Ishino
IPC分类号： B63H1100
CPC分类号： B63H11/08
摘要： A jet propelled watercraft having an improved extension assembly for dampening pulsations from the impeller of the jet propulsion unit and also an improved exhaust system having a separate idle discharge for permitting lower idle speeds without restriction of the idle exhaust gas flow.
摘要翻译：一种具有改进的延伸组件的喷射器，其具有用于衰减来自喷射推进单元的叶轮的脉动，并且还具有改进的排气系统，该排气系统具有单独的怠速排放，以允许较低的怠速而不限制怠速废气流。

3. 发明授权

US08722622B2 FGF21 conjugates and anti-diabetic uses thereof 失效
标题翻译： FGF21缀合物及其抗糖尿病用途
公开(公告)号：US08722622B2
公开(公告)日：2014-05-13
申请号：US13289533
申请日：2011-11-04
申请人： Tapan Kanti Das , Tamara Shafer Hodge , Tetsuya Ishino , Nancy Jane Levin , Moorthy Sitharamaiah Suriyanarayana Palanki , Erin Kristen Parsons , Bernard Norman Violand
发明人： Tapan Kanti Das , Tamara Shafer Hodge , Tetsuya Ishino , Nancy Jane Levin , Moorthy Sitharamaiah Suriyanarayana Palanki , Erin Kristen Parsons , Bernard Norman Violand
IPC分类号： A61K38/18 , A61K39/395
CPC分类号： C07K16/40 , A61K38/00 , A61K47/6815 , A61K47/6835 , A61K47/6889 , C07K14/50 , C07K2319/30 , C07K2319/31 , C07K2319/75
摘要： The present invention provides a FGF21 molecule covalently attached to the combining site of an antibody via a linker, wherein the linker is covalently attached to the side chain of a linking residue within FGF21. Various uses of the compounds are provided, including methods to prevent or treat diabetes or diabetes-related conditions.
摘要翻译：本发明提供通过接头共价连接到抗体的结合位点的FGF21分子，其中接头共价连接到FGF21内的连接残基的侧链上。提供了化合物的各种用途，包括预防或治疗糖尿病或糖尿病相关病症的方法。

4. 发明申请

US20120282279A1 Anti-Diabetic Compounds 失效
标题翻译：抗糖尿病化合物
公开(公告)号：US20120282279A1
公开(公告)日：2012-11-08
申请号：US13289533
申请日：2011-11-04
申请人： Tapan Kanti Das , Tamara Shafer Hodge , Tetsuya Ishino , Nancy Jane Levin , Moorthy Sitharamaiah Suriyanarayana Palanki , Erin Kristan Parsons , Bernard Norman Violand
发明人： Tapan Kanti Das , Tamara Shafer Hodge , Tetsuya Ishino , Nancy Jane Levin , Moorthy Sitharamaiah Suriyanarayana Palanki , Erin Kristan Parsons , Bernard Norman Violand
IPC分类号： A61K39/44 , A61P3/10 , A61P3/04 , A61P3/08 , A61P9/12 , A61P1/16 , A61P9/00 , A61P5/48 , C07K19/00 , A61P3/06
CPC分类号： C07K16/40 , A61K38/00 , A61K47/6815 , A61K47/6835 , A61K47/6889 , C07K14/50 , C07K2319/30 , C07K2319/31 , C07K2319/75
摘要： The present invention provides a FGF21 molecule covalently attached to the combining site of an antibody via a linker, wherein the linker is covalently attached to the side chain of a linking residue within FGF21. Various uses of the compounds are provided, including methods to prevent or treat diabetes or diabetes-related conditions.
摘要翻译：本发明提供通过接头共价连接到抗体的结合位点的FGF21分子，其中接头共价连接到FGF21内的连接残基的侧链上。提供了化合物的各种用途，包括预防或治疗糖尿病或糖尿病相关病症的方法。

5. 发明授权

US06623321B2 Air induction system for small watercraft 失效
公开(公告)号：US06623321B2
公开(公告)日：2003-09-23
申请号：US10212635
申请日：2002-08-02
申请人： Tetsuya Ishino
发明人： Tetsuya Ishino
IPC分类号： B63H2110
CPC分类号： F02M35/167 , B63B35/731 , B63H21/24 , B63J2/06 , F02M35/168
摘要： An induction system for a watercraft is configured to guide air into an engine disposed within the watercraft for combustion therein. The induction system includes an inlet assembly. The inlet assembly includes various constructions for enhancing water preclusive effects.

6. 发明授权

US06517397B1 Air induction system for small watercraft 失效
标题翻译：小型船舶空气感应系统
公开(公告)号：US06517397B1
公开(公告)日：2003-02-11
申请号：US09669484
申请日：2000-09-25
申请人： Yoshihiro Gohara , Yoshihide Fukuda , Tetsuya Ishino
发明人： Yoshihiro Gohara , Yoshihide Fukuda , Tetsuya Ishino
IPC分类号： B63H2110
CPC分类号： F02M35/10144 , B63B35/731 , B63J2/06 , F02B61/045 , F02M35/116 , F02M35/1261 , F02M35/168
摘要： An induction system for a watercraft includes a first intake air chamber communicating with at least one combustion chamber of an engine of the watercraft, and a second intake air chamber communicating with the first intake air chamber via a conduit. The second intake air chamber may be arranged in various orientations and/or with various other features which improve attenuation of induction noises and/or the preclusion of water from entering the engine through the induction system.
摘要翻译：用于船舶的感应系统包括与船舶的发动机的至少一个燃烧室连通的第一进气室和经由导管与第一进气室连通的第二进气室。第二进气室可以以各种取向和/或各种其它特征布置，这些特征改善了感应噪声的衰减和/或通过感应系统进入发动机的排水。

7. 发明授权

US07980070B2 Exhaust gas cooling system for engine 有权
标题翻译：发动机排气冷却系统
公开(公告)号：US07980070B2
公开(公告)日：2011-07-19
申请号：US11946699
申请日：2007-11-28
申请人： Tetsuya Mashiko , Tetsuya Ishino
发明人： Tetsuya Mashiko , Tetsuya Ishino
IPC分类号： F01N3/00
CPC分类号： F01N3/04 , F01N13/004 , F01N13/12 , F01N2470/24 , F01N2490/04 , F01N2490/08 , Y02T10/20
摘要： An exhaust gas cooling system for an engine includes an exhaust gas conduit having an inner tube defining an exhaust gas passage and an exhaust coupler surrounding the inner tube and defining a cooling water passage together with the inner tube therebetween, and a water-lock coupled with a downstream end of the exhaust gas conduit through an exhaust gas conduit coupling section which extends from an upstream end of the water-lock. The exhaust gas conduit coupling section and the exhaust coupler are coupled with each other and the inner tube extends into the interior of the water-lock. A downstream end part of the inner tube can be formed to be a wide portion having a bell mouth configuration. A diameter of the downstream end part becomes larger as a portion thereof exists closer to the end of the downstream end part. The exhaust gas cooling system for the engine can be provided for a water vehicle.
摘要翻译：用于发动机的废气冷却系统包括排气导管，其具有限定排气通道的内管和围绕内管的排气联接器，并且与其间的内管一起限定冷却水通道，并且将水锁与通过从水锁的上游端延伸的排气管道连接部分排出废气导管的下游端。排气管道联接部分和排气联接器彼此联接并且内管延伸到水锁的内部。内管的下游端部可以形成为具有喇叭口构造的宽部。下游端部的直径越靠近下游端部的端部越靠近，用于发动机的废气冷却系统可以提供给水车辆。

8. 发明申请

US20080141666A1 EXHAUST GAS COOLING SYSTEM FOR ENGINE 有权
标题翻译：发动机排气冷却系统
公开(公告)号：US20080141666A1
公开(公告)日：2008-06-19
申请号：US11946699
申请日：2007-11-28
申请人： Tetsuya Mashiko , Tetsuya Ishino
发明人： Tetsuya Mashiko , Tetsuya Ishino
IPC分类号： F01N3/02
CPC分类号： F01N3/04 , F01N13/004 , F01N13/12 , F01N2470/24 , F01N2490/04 , F01N2490/08 , Y02T10/20
摘要： An exhaust gas cooling system for an engine includes an exhaust gas conduit having an inner tube defining an exhaust gas passage and an exhaust coupler surrounding the inner tube and defining a cooling water passage together with the inner tube therebetween, and a water-lock coupled with a downstream end of the exhaust gas conduit through an exhaust gas conduit coupling section which extends from an upstream end of the water-lock. The exhaust gas conduit coupling section and the exhaust coupler are coupled with each other and the inner tube extends into the interior of the water-lock. A downstream end part of the inner tube can be formed to be a wide portion having a bell mouth configuration. A diameter of the downstream end part becomes larger as a portion thereof exists closer to the end of the downstream end part. The exhaust gas cooling system for the engine can be provided for a water vehicle.
摘要翻译：用于发动机的废气冷却系统包括排气导管，其具有限定排气通道的内管和围绕内管的排气联接器，并且与其间的内管一起限定冷却水通道，并且将水锁与通过从水锁的上游端延伸的排气管道连接部分排出废气导管的下游端。排气管道联接部分和排气联接器彼此联接，并且内管延伸到水锁的内部。内管的下游端部可以形成为具有喇叭口构造的宽部。下游端部的直径越靠近下游端部的端部越靠近，用于发动机的废气冷却系统可以提供给水车辆。

9. 发明授权

US06827048B2 Cooling system for marine engine 有权
标题翻译：船用发动机冷却系统
公开(公告)号：US06827048B2
公开(公告)日：2004-12-07
申请号：US10112809
申请日：2002-03-29
申请人： Naoki Kinomoto , Tetsuya Ishino
发明人： Naoki Kinomoto , Tetsuya Ishino
IPC分类号： B63H2138
CPC分类号： F01P3/20 , B63B35/731 , B63H21/14 , B63H21/24 , B63H21/383 , F01P11/0276 , F01P2050/02 , F01P2050/04 , F01P2060/04 , F01P2060/16
摘要： A cooling system particularly suited for use in a small watercraft, which supplies coolant to, and evacuates coolant from, an engine of the watercraft. The engine includes an engine body defining at least one water jacket therein. An engine coolant supply passage desirably routes the coolant into thermal communication with a portion of an exhaust system, such as an exhaust manifold, before supplying the coolant to the water jacket of the engine. When the engine is shut off, coolant is permitted to drain from the water jacket through a drain passage. The drain passage is connected to the coolant supply passage at a position upstream from the exhaust system such that coolant draining from the engine travels in a reverse direction through the supply passage and is drained from the watercraft cooling system. Upon normal operation of the engine, a restriction orifice within the drain passage permits only a relatively small amount of coolant to be supplied to the engine water jacket, without being routed into thermal communication with the exhaust system.
摘要翻译：一种特别适用于小型船舶的冷却系统，该系统向船只的发动机提供冷却液，并从其中抽出冷却剂。发动机包括在其中限定至少一个水套的发动机主体。发动机冷却剂供应通道期望在将冷却剂供应到发动机的水套之前使冷却剂与诸如排气歧管的排气系统的一部分热连通。当发动机关闭时，允许冷却剂从水套通过排水通道排出。排水通道在排气系统上游的位置连接到冷却剂供应通道，使得从发动机排出的冷却剂沿相反方向通过供应通道行进并从船只冷却系统排出。在发动机正常运行时，排水通道内的限流孔仅允许相对较少量的冷却剂供给发动机水套，而不会与排气系统进行热连通。

10. 发明授权

US06435924B2 Air induction system for small watercraft 有权
标题翻译：小型船舶空气感应系统
公开(公告)号：US06435924B2
公开(公告)日：2002-08-20
申请号：US09734954
申请日：2000-12-11
申请人： Tetsuya Ishino
发明人： Tetsuya Ishino
IPC分类号： B63H2110
CPC分类号： F02M35/167 , B63B35/731 , B63H21/24 , B63J2/06 , F02M35/168
摘要： An induction system for a watercraft is configured to guide air into an engine disposed within the watercraft for combustion therein. The induction system includes an inlet assembly. The inlet assembly includes various constructions for enhancing water preclusive effects.
摘要翻译：用于船舶的感应系统被配置为将空气引导到布置在船舶内的发动机中以在其中燃烧。感应系统包括入口组件。入口组件包括用于增强排水效果的各种结构。

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