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    • 2. 发明授权
    • Phosphorus-containing isoprenoid derivatives
    • 含磷类异戊二烯衍生物
    • US5453524A
    • 1995-09-26
    • US199231
    • 1994-02-22
    • Katsuya TagamiIchirou YoshidaNaoki KobayashiYoshio FukudaYoshihito EguchiMakoto NakagawaHironobu HiyoshiHironori IkutaMakoto KainoKenji HayashiIssei OhtsukaShinya AbeShigeru Souda
    • Katsuya TagamiIchirou YoshidaNaoki KobayashiYoshio FukudaYoshihito EguchiMakoto NakagawaHironobu HiyoshiHironori IkutaMakoto KainoKenji HayashiIssei OhtsukaShinya AbeShigeru Souda
    • A61K31/66A61P3/06C07C211/21C07C233/03C07F9/38C07F9/40C07F9/02
    • C07F9/405C07C211/21C07C233/03C07F9/3808C07F9/3826C07F9/3843C07F9/3873C07F9/4006C07F9/4015C07F9/4025
    • The present invention provides a phosphorus-containing isoprenoid derivative represented by the following general formula (I) or a pharmacologically acceptable salt thereof, which is useful as a preventive and therapeutic agent for diseases for which a squalene synthetase inhibiting action is efficacious: ##STR1## wherein R.sup.1 and R.sup.2 each represent a hydrogen atom, a lower alkyl, cycloalkyl, alkenyl or alkynyl group, an aryl group which may be substituted, an arylalkyl group in which the aryl group may be substituted, or a heteroaryl or heteroarylalkyl group: R.sup.3 and R.sup.4 each represent a hydrogen atom, a lower alkyl group or an alkali metal; Y represents a group represented by the formula: ##STR2## (wherein R.sup.5 and R.sup.6 each represent a hydrogen atom, a lower alkyl group or an alkali metal or a group represented by the formula: --CO.sub.2 R.sup.7 (wherein R.sup.7 represents a hydrogen atom, a lower alkyl group or an alkali metal); Z represents a group represented by the Formula: --(CH.sub.2).sub.m -- (wherein m is an integer of 0 to 3), a group represented by the formula: --(CH.sub.2).sub.p --CH.dbd.CH--(CH.sub.2).sub.q -- (wherein p is 0 or 1 and q is 1 or 2) or a group represented by the Formula: ##STR3## (wherein R.sup.8 represents a hydrogen atom or a lower alkyl group; A represents an alkylene chain which has 1 to 5 carbon atoms and which may have a substituent on each carbon atom; and r is zero or an integer of 1 to 5); and n is zero or an integer of 1 to 5.
    • PCT No.PCT / JP92 / 01082 Sec。 371日期:1994年2月22日 102(e)日期1994年2月22日PCT提交1992年8月27日PCT公布。 公开号WO93 / 04073 日本1993年3月4日。本发明提供由以下通式(I)表示的含磷类异戊二烯衍生物或其药理学上可接受的盐,其可用作抑制角鲨烯合成酶的疾病的预防和治疗剂 作用有效:其中R 1和R 2各自表示氢原子,低级烷基,环烷基,烯基或炔基,可被取代的芳基,芳基可以被取代的芳基烷基 或杂芳基或杂芳基烷基:R 3和R 4各自表示氢原子,低级烷基或碱金属; Y表示由下式表示的基团:其中R 5和R 6各自表示氢原子,低级烷基或碱金属或由下式表示的基团:-CO 2 R 7(其中R 7表示氢原子, 低级烷基或碱金属); Z表示由下式表示的基团: - (CH 2)m - (其中m为0至3的整数),由下式表示的基团: - (CH 2)p-CH = CH-(CH 2)q - (其中p为0或1,q为1或2)或由下式表示的基团:其中R8表示氢原子或低级烷基; A表示亚烷基 具有1至5个碳原子并且在每个碳原子上可以具有取代基的链;并且r为0或1至5的整数); n为0或1至5的整数。
    • 4. 发明授权
    • On-vehicle apparatus theft deterrence system
    • 车载设备盗窃威慑系统
    • US07550869B2
    • 2009-06-23
    • US11812806
    • 2007-06-21
    • Takashi HiguchiIchirou Yoshida
    • Takashi HiguchiIchirou Yoshida
    • B60R25/04
    • B60R25/24B60R2325/105
    • A navigation apparatus is detachably installed to a vehicle and is lockable to implement activation lock of the navigation apparatus. The navigation apparatus stores all of manufacturer serial numbers of wireless IC tags and an ID code. Each IC tag stores the ID code and is attached to a corresponding one of portable items, such as a driver's license, a cellular phone, a wallet and a commutation pass, which are generally used daily. In the navigation system, the manufacturer serial numbers are registered in such a manner that each of manufacturer serial numbers is linked with an icon of a corresponding one of the portable items. When the ID code of the IC tag, which is attached to the corresponding portable item carried by a vehicle occupant, is determined to be valid, the activation lock of the navigation apparatus is released.
    • 导航装置可拆卸地安装在车辆上,并可锁定以实现导航装置的启动锁定。 导航装置存储无线IC标签的所有制造商序列号和ID码。 每个IC标签存储ID代码,并且被附加到通常每天使用的便携式项目中的相应的一个,例如驾驶执照,蜂窝电话,钱包和换向券。 在导航系统中,制造商序列号以这样一种方式进行登记,即每个制造商序列号与便携式物品中相应的一个的图标相链接。 当确定附着在车辆乘客所携带的对应便携式物品上的IC标签的ID码有效时,导航装置的启动锁定被解除。
    • 5. 发明授权
    • Intersection information provision system and driving assist system
    • 交叉口信息提供系统和驾驶辅助系统
    • US07777616B2
    • 2010-08-17
    • US11889077
    • 2007-08-09
    • Kenji MaseIchirou Yoshida
    • Kenji MaseIchirou Yoshida
    • B60Q1/00
    • G08G1/164
    • In an intersection information provision system, multiple cameras are installed oriented towards the direction where each road extends from the intersection. Each camera captures as an image or video the state ranging from the intersection to each road. Therefore, the area of the captured image by each camera is narrowed down. When this captured image is displayed in a display unit of a navigation apparatus in a vehicle, the driver of the vehicle can perform safety check easily. Furthermore, according to the traveling direction of the vehicle at the intersection, a display pattern of several captured images to be displayed is determined. According to the determined display pattern, multiple captured images are displayed in order. Therefore, image information required to pass through the intersection safely can be offered without shortage to the driver of the vehicle.
    • 在交叉口信息提供系统中,安装多个照相机,朝向每个道路从交叉路口延伸的方向。 每个相机拍摄的图像或视频的状态范围从交叉路口到每条道路。 因此,每个摄像机拍摄的图像的面积变窄。 当该拍摄图像显示在车辆中的导航装置的显示单元中时,车辆的驾驶员可以容易地执行安全检查。 此外,根据车辆在十字路口的行进方向,确定要显示的几个拍摄图像的显示图案。 根据确定的显示图案,依次显示多个拍摄图像。 因此,可以提供通过交叉点安全地所需的图像信息,而不会不利于车辆的驾驶员。
    • 8. 发明申请
    • Intersection information provision system and driving assist system
    • 交叉口信息提供系统和驾驶辅助系统
    • US20080055056A1
    • 2008-03-06
    • US11889077
    • 2007-08-09
    • Kenji MaseIchirou Yoshida
    • Kenji MaseIchirou Yoshida
    • B60Q1/00
    • G08G1/164
    • In an intersection information provision system, multiple cameras are installed oriented towards the direction where each road extends from the intersection. Each camera captures as an image or video the state ranging from the intersection to each road. Therefore, the area of the captured image by each camera is narrowed down. When this captured image is displayed in a display unit of a navigation apparatus in a vehicle, the driver of the vehicle can perform safety check easily. Furthermore, according to the traveling direction of the vehicle at the intersection, a display pattern of several captured images to be displayed is determined. According to the determined display pattern, multiple captured images are displayed in order. Therefore, image information required to pass through the intersection safely can be offered without shortage to the driver of the vehicle.
    • 在交叉口信息提供系统中,安装多个照相机,朝向每个道路从交叉路口延伸的方向。 每个相机拍摄的图像或视频的状态范围从交叉路口到每条道路。 因此,每个摄像机拍摄的图像的面积变窄。 当该拍摄图像显示在车辆中的导航装置的显示单元中时,车辆的驾驶员可以容易地执行安全检查。 此外,根据车辆在十字路口的行进方向,确定要显示的几个拍摄图像的显示图案。 根据确定的显示图案,依次显示多个拍摄图像。 因此,可以提供通过交叉点安全地所需的图像信息,而不会不利于车辆的驾驶员。
    • 9. 发明申请
    • On-vehicle apparatus theft deterrence system
    • 车载设备盗窃威慑系统
    • US20070296563A1
    • 2007-12-27
    • US11812806
    • 2007-06-21
    • Takashi HiguchiIchirou Yoshida
    • Takashi HiguchiIchirou Yoshida
    • B60R25/10
    • B60R25/24B60R2325/105
    • A navigation apparatus is detachably installed to a vehicle and is lockable to implement activation lock of the navigation apparatus. The navigation apparatus stores all of manufacturer serial numbers of wireless IC tags and an ID code. Each IC tag stores the ID code and is attached to a corresponding one of portable items, such as a driver's license, a cellular phone, a wallet and a commutation pass, which are generally used daily. In the navigation system, the manufacturer serial numbers are registered in such a manner that each of manufacturer serial numbers is linked with an icon of a corresponding one of the portable items. When the ID code of the IC tag, which is attached to the corresponding portable item carried by a vehicle occupant, is determined to be valid, the activation lock of the navigation apparatus is released.
    • 导航装置可拆卸地安装在车辆上,并可锁定以实现导航装置的启动锁定。 导航装置存储无线IC标签的所有制造商序列号和ID码。 每个IC标签存储ID代码,并且被附加到通常每天使用的便携式项目中的相应的一个,例如驾驶执照,蜂窝电话,钱包和换向券。 在导航系统中,制造商序列号以这样一种方式进行登记,即每个制造商序列号与便携式物品中相应的一个的图标相链接。 当确定附着在车辆乘客所携带的对应便携式物品上的IC标签的ID码有效时,导航装置的启动锁定被解除。