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    • 3. 发明授权
    • Method of producing water-insolubilized regenerated collagen fiber
    • 生产水不溶性再生胶原纤维的方法
    • US06242573B1
    • 2001-06-05
    • US09431669
    • 1999-11-01
    • Masaoki GotoShinichi SakashitaKunihiko Matsumura
    • Masaoki GotoShinichi SakashitaKunihiko Matsumura
    • A61K3817
    • D01F4/00
    • A regenerated collagen fiber is subjected to water-insolubilizing treatment with a monofunctional epoxy compound to produce a water-insolubilized regenerated collagen fiber which can substantially maintain the color and the high knot tenacity, inherent in the collagen. Where the monofunctional epoxy compound is an epihalohydrin, a regenerated collagen fiber can be treated with this epihalohydrin and a sulfur compound to produce a water-insolubilized regenerated collagen fiber which can be permanent-wave set. In addition, the water-insolubilized regenerated collagen fiber can be converted into a fiber which can be permanent-wave set, by introducing a disulfide linkage into carboxylic groups of the collagen, which remain unmodified by the insolubilizing treatment.
    • 再生胶原纤维用单官能环氧化合物进行水不溶化处理以产生水不溶性的再生胶原纤维,其可以基本上保持胶原固有的颜色和高结强度。 当单官能环氧化合物是表卤代醇时,再生的胶原纤维可用该表卤代醇和硫化合物处理,以产生可以永久凝固的不溶于水的再生胶原纤维。 此外,水不溶性再生胶原纤维可以通过将二硫键引入胶原蛋白的羧基,通过不溶化处理而保持未改性,可以将其变成可永久凝固的纤维。