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1. 发明授权

US5576212A Oxidizing composition in powder form 失效
标题翻译：粉末形式的氧化组合物
公开(公告)号：US5576212A
公开(公告)日：1996-11-19
申请号：US338740
申请日：1994-11-09
申请人： Katsu Honzawa , Seiji Kawaguchi , Kazuhiro Atsumi , Fumihiko Shimomura , Takahiko Ishiguro , Hisaya Motojima
发明人： Katsu Honzawa , Seiji Kawaguchi , Kazuhiro Atsumi , Fumihiko Shimomura , Takahiko Ishiguro , Hisaya Motojima
IPC分类号： G01N21/76 , G01N33/52 , G01N33/58
CPC分类号： G01N33/582 , G01N33/52 , Y10T436/10
摘要： An oxidizing composition in the form of powder for oxidizing a chemiluminescent substance, including an oxidizing agent and a binder.
摘要翻译：一种用于氧化化学发光物质（包括氧化剂和粘合剂）的粉末形式的氧化组合物。

2. 发明授权

US5523845A A fiber optic device for measuring liquids which are drawn into an end of the device to a predetermined distance from the end of the optical fibers 失效
标题翻译：一种用于测量液体的光纤装置，其被拉入设备的端部到与光纤端部预定距离
公开(公告)号：US5523845A
公开(公告)日：1996-06-04
申请号：US378369
申请日：1995-01-25
申请人： Katsu Honzawa , Kazuhiro Atsumi , Humihiko Shimomura , Seiji Kawaguchi , Yuichiro Sakamoto , Hisaya Motojima , Masayuki Masuko , Tsuyoshi Hayakawa
发明人： Katsu Honzawa , Kazuhiro Atsumi , Humihiko Shimomura , Seiji Kawaguchi , Yuichiro Sakamoto , Hisaya Motojima , Masayuki Masuko , Tsuyoshi Hayakawa
IPC分类号： G01N21/63 , G01N1/00 , G01N21/15 , G01N21/17 , G01N35/10 , G01N21/11 , G01N21/64 , G01N21/65
CPC分类号： G01N21/15 , G01N2035/1062
摘要： The first branch 1a of the optical fiber 1 is connected to the light source 2, and the second branch 1b is connected to the optical measuring unit 3. A taper-shaped tip member 8 is fitted to a tip end of the optical fiber unit 1 with the use of a jig member 4. The inner hollow space 7 in the tip member 8 is connected with the air suction device 11, through the gap 5 formed between the optical fiber unit 1 and the jig member 4 and the air suction tube 10. The air suction device 11 discharges air from the inner hollow space 7 to suck liquid through the through-hole 6 into the inner hollow space. The air suction device 11 is controlled by the controller 12. Because the optical fiber unit can directly irradiate liquid with light, measurement can be performed with high sensitivity. The optical fiber unit is prevented from contamination.
摘要翻译：光纤1的第一分支1a连接到光源2，第二分支1b连接到光学测量单元3.锥形尖端构件8装配到光纤单元1的末端通过使用夹具构件4.通过形成在光纤单元1和夹具构件4之间的间隙5和吸气管10，尖端构件8中的内部中空空间7与吸气装置11连接吸气装置11从内部中空空间7排出空气，通过通孔6将液体吸入内部中空空间。吸气装置11由控制器12控制。由于光纤单元可以直接用光照射液体，因此可以以高灵敏度进行测量。防止光纤单元的污染。

3. 发明授权

US5637874A Apparatus and method for measuring chemiluminescence 失效
标题翻译：用于测量化学发光的装置和方法
公开(公告)号：US5637874A
公开(公告)日：1997-06-10
申请号：US393387
申请日：1995-02-23
申请人： Katsu Honzawa , Kazuhiro Atsumi , Fumihiko Shimomura , Masayuki Masuko , Tsuyoshi Hayakawa
发明人： Katsu Honzawa , Kazuhiro Atsumi , Fumihiko Shimomura , Masayuki Masuko , Tsuyoshi Hayakawa
IPC分类号： G01N21/75 , C12M1/34 , G01N21/03 , G01N21/76
CPC分类号： G01N21/76
摘要： The present invention provides a chemiluminescence measuring apparatus which is small in size and high in operability and has a function of performing accurate quantitative analysis and the like. The apparatus includes at least a box-like housing having an opening, a cover provided on a top surface of the housing and having a through hole for introducing a first detachable vessel into the inner space of the housing, a holder having a concave portion and enclosing the opening of the housing, the hollow chamber having an opening at a side wall thereof and partially housing a second vessel, a photo-sensing unit for detecting luminescence from the second vessel via the through hole of the hollow chamber, and a shutter mechanism for intermittently cutting optical path between the photo-sensing unit and the second vessel. Particularly, the shutter mechanism includes a rotatable hollow chamber partially housing the vessel, provided in the hollow chamber and having an opening at a side wall thereof, and a driving motor rotating the rotatable hollow chamber.
摘要翻译：本发明提供一种尺寸小，操作性高的化学发光测定装置，具有进行准确的定量分析等功能。该装置至少包括具有开口的盒状壳体，设置在壳体的顶表面上的盖，并具有用于将第一可拆卸容器引入壳体的内部空间的通孔，具有凹部和封闭壳体的开口，中空室在其侧壁处具有开口并且部分地容纳第二容器，用于经由中空室的通孔检测来自第二容器的发光的光感测单元，以及快门机构用于间歇地切割感光单元和第二容器之间的光路。特别地，闸门机构包括：可旋转的中空室，其设置在中空室中，部分地容纳容器，并且在其侧壁具有开口;以及驱动马达，其旋转可旋转中空室。

4. 发明授权

US5286848A Lanthanide cryptate of trisphenanthroline 失效
标题翻译：三菲啉的镧系元素穴晶
公开(公告)号：US5286848A
公开(公告)日：1994-02-15
申请号：US51819
申请日：1993-04-26
申请人： Katsu Honzawa
发明人： Katsu Honzawa
IPC分类号： C07D487/22 , G01N33/533 , C07K3/08 , C07K13/00
CPC分类号： C07D487/22 , G01N33/533 , Y10S530/83
摘要： A photoactive lanthanide complex of 2,2',2",9,9',9"-bis[nitrilotri(methylene)]tris(1,10-phenanthroline) and its functional derivative capable of bonding with substrate such as polymer and protein are provided. The lanthanide complex is usable for photosynthesis and photoimmunoassay.
摘要翻译： 2,2'，2“，9,9'，9” - 双[次氮基（亚甲基）]三（1,10-菲咯啉）及其与底物如聚合物键合的功能衍生物的光活性镧系元素络合物并提供蛋白质。镧系元素络合物可用于光合作用和光免疫测定。

5. 发明授权

US07608404B2 Disease determination method, data generation method for disease determination and data generation system for disease determination 失效
标题翻译：疾病确定方法，疾病确定数据生成方法和疾病测定数据生成系统
公开(公告)号：US07608404B2
公开(公告)日：2009-10-27
申请号：US10533116
申请日：2003-10-30
申请人： Akimitsu Kakui , Katsu Honzawa , Yukiko Sato
发明人： Akimitsu Kakui , Katsu Honzawa , Yukiko Sato
IPC分类号： G01N33/53 , G01N33/566
CPC分类号： G01N21/6428 , G01N21/77 , G01N2021/6417 , G01N2021/7786
摘要： Supernatant of the urinary sample (SP1) was mixed with an acid or alkali and heated (SP2) and the sample for fluorescence assay was prepared after adjusting its acidity to alkaline (SP3). Next, using fluorometry, three-dimensional fluorescence spectrum consisted of an excitation light wavelength, fluorescence wavelength and fluorescence intensity (SP4). Then, a relative maximum peak is detected as a specific point in the three-dimensional fluorescence spectrum to specify a specific point attribute (peak number, peak position and fluorescence intensity) and then the urinary sample is sorted based on the attribute (SP5). Finally, the presence or absence of a disease such as a malignant tumor is determined based on the sorting results of the urinary sample (P6).
摘要翻译：将尿样（SP1）的上清液与酸或碱混合并加热（SP2），并在调节其酸性至碱性（SP 3）后制备用于荧光测定的样品。接下来，使用荧光测定，三维荧光光谱由激发光波长，荧光波长和荧光强度（SP4）组成。然后，检测相对最大峰作为三维荧光光谱中的特定点，以指定特定点属性（峰值，峰位置和荧光强度），然后基于属性（SP5）对尿样进行分类。最后，基于尿样（P6）的分选结果确定恶性肿瘤等疾病的存在或不存在。

6. 发明申请

US20050019844A1 Method of detecting malignant tumor and detection kit 审中-公开
标题翻译：检测恶性肿瘤和检测试剂盒的方法
公开(公告)号：US20050019844A1
公开(公告)日：2005-01-27
申请号：US10495876
申请日：2002-11-20
申请人： Katsu Honzawa
发明人： Katsu Honzawa
IPC分类号： G01N33/50 , G01N21/78 , G01N33/483 , G01N33/574
CPC分类号： G01N33/57488
摘要： A malignant tumor detection method suitable for the primary screening for a malignant tumor, and a detection kit using the method are provided. Considering various amino group-containing low molecular weight tumor markers in a sample, a tumor marker is labeled under suitable conditions using an amino group labeling dye which reacts specifically with it. The labeled tumor marker is subjected to spectroscopic measurement, and the tumor marker amount present in the sample is calculated. The presence or absence of a malignant tumor is detected by comparing the tumor marker amount with a threshold value for the tumor marker obtained from healthy persons. The series of these steps is performed using the detection kit.
摘要翻译：提供了适用于恶性肿瘤的初步筛选的恶性肿瘤检测方法和使用该方法的检测试剂盒。考虑到样品中含有各种含氨基的低分子量肿瘤标志物，使用与其特异性反应的氨基标记染料，在合适的条件下标记肿瘤标志物。对标记的肿瘤标记物进行光谱测量，并计算样品中存在的肿瘤标志物量。通过将肿瘤标志物量与从健康人获得的肿瘤标志物的阈值进行比较来检测是否存在恶性肿瘤。这些步骤的一系列使用检测工具进行。

7. 发明授权

US5019416A Method of modifying the surface of a particle comprising a magnetic particle 失效
标题翻译：改性包含磁性颗粒的颗粒表面的方法
公开(公告)号：US5019416A
公开(公告)日：1991-05-28
申请号：US497200
申请日：1990-03-22
申请人： Katsu Honzawa
发明人： Katsu Honzawa
IPC分类号： A61B10/00 , B01J19/00 , C09C3/08 , C09C3/10 , G01N33/543 , G01N33/544 , G01N33/553
CPC分类号： G01N33/5434 , G01N2446/80
摘要： A particle comprising a magnetic particle is placed in a liquid having a monomolecular film formed on its surface. Then, the particle is pulled up by means of a pair of electromagets facing each other with the air-liquid interface present therebetween so that the particle passes through the interface. As a result, a monomolecular coat is formed on the surface of the particle. A monomolecular built-up coat is formed by repeating the above procedure predetermined times.

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