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1. 发明申请

US20110256193A1 Use Of Copolymers Based On Polyethers And Vinyl Monomers As Stabilizing Agents For Emulsions 审中-公开
标题翻译：使用基于聚醚和乙烯基单体的共聚物作为乳液的稳定剂
公开(公告)号：US20110256193A1
公开(公告)日：2011-10-20
申请号：US13141481
申请日：2009-12-10
申请人： Kathrin Meyer-Bohm , Rainer Dobrawa , Karl Kolter
发明人： Kathrin Meyer-Bohm , Rainer Dobrawa , Karl Kolter
IPC分类号： A61K8/06 , A61K9/107 , A61K47/32
CPC分类号： B01F17/005 , A61K8/06 , A61K8/062 , A61K8/8182 , A61K8/86 , A61Q19/00
摘要： Use of water-soluble or water-dispersible copolymers which are obtained by polymerization of vinyl acetate and N-vinyllactams in the presence of a polyether, as stabilizing agents for emulsions.
摘要翻译：在聚醚存在下通过聚合乙酸乙烯酯和N-乙烯基内酰胺获得的水溶性或水分散性共聚物作为乳液的稳定剂的用途。

2. 发明申请

US20090036550A1 Copolymers Based on Polyalkylene Oxide-Modified N-Vinyl Lactam Copolymers 审中-公开
标题翻译：基于聚环氧烷改性N-乙烯基内酰胺共聚物的共聚物
公开(公告)号：US20090036550A1
公开(公告)日：2009-02-05
申请号：US12096527
申请日：2006-11-30
申请人： Nathalie Bouillo , Alexander Khvorost , Ingo Munster , Rainer Dobrawa , Kathrin Meyer-Bohm , Ronald Frans Maria Lange
发明人： Nathalie Bouillo , Alexander Khvorost , Ingo Munster , Rainer Dobrawa , Kathrin Meyer-Bohm , Ronald Frans Maria Lange
IPC分类号： A61K47/32 , C08F26/06
CPC分类号： A61K8/90 , A61K8/86 , A61K47/32 , A61Q19/00 , C08G65/33348 , C08G81/025 , C08G2261/126 , C08L71/02 , C08L2205/05 , C08L39/06
摘要： Vinyllactam copolymers modified with polyalkylene oxide side-chains, and use thereof as solubilizers for substances which are sparingly soluble in water, and preparations comprising such copolymers.
摘要翻译：用聚环氧烷侧链改性的乙烯基内酰胺共聚物及其作为微溶于水的物质的增溶剂的用途，以及包含这些共聚物的制剂。

3. 发明申请

US20080300320A1 Use of Polyvinyl Lactam-Polyalkylene Block Copolymers as Solubilisers for Poorly Water-Soluble Compounds 审中-公开
标题翻译：使用聚乙烯基内酰胺 - 聚亚烷基嵌段共聚物作为不溶于水的化合物的增溶剂
公开(公告)号：US20080300320A1
公开(公告)日：2008-12-04
申请号：US12096544
申请日：2006-11-30
申请人： Ronald Frans Maria Lange , Nathalie Bouillo , Ingo Munster , Klemens Mathauer , Kathrin Meyer-Bohm , Rainer Dobrawa
发明人： Ronald Frans Maria Lange , Nathalie Bouillo , Ingo Munster , Klemens Mathauer , Kathrin Meyer-Bohm , Rainer Dobrawa
IPC分类号： A61K47/30 , A61K8/90 , A01N25/00 , A23L1/00
CPC分类号： A61K47/34 , A01N25/02 , A01N25/30 , A23L29/00 , A23L29/288 , A61K8/90 , A61K2800/54 , A61Q19/00
摘要： Use of polyvinyllactam-polyalkylene oxide block copolymers as solubilizers for sub-stances which are sparingly soluble in water.
摘要翻译：使用聚乙烯内酰胺 - 聚环氧烷嵌段共聚物作为微溶于水的子体的增溶剂。

4. 发明申请

US20080293828A1 Use of Copolymers as Solubilizers For Slightly Water-Soluble Compounds 有权
标题翻译：共聚物用作轻微水溶性化合物的增溶剂
公开(公告)号：US20080293828A1
公开(公告)日：2008-11-27
申请号：US12092676
申请日：2006-10-25
申请人： Nathalie Bouillo , Marianna Pierobon , Ralf Widmaier , Rainer Dobrawa , Kathrin Meyer-Bohm , Ronald Frans-Maria Lange
发明人： Nathalie Bouillo , Marianna Pierobon , Ralf Widmaier , Rainer Dobrawa , Kathrin Meyer-Bohm , Ronald Frans-Maria Lange
IPC分类号： A61K47/34 , A61K8/86
CPC分类号： A61K47/34 , A61K8/86 , A61K9/08 , A61K9/146 , A61K9/2077 , A61Q19/00 , C08F218/08 , C08F220/06
摘要： The use of copolymers obtained by free-radical polymerization of a mixture of i) 30 to 80% by weight of N-vinyllactam, ii) 10 to 50% by weight of vinyl acetate, and iii) 10 to 50% by weight of a polyether, with the proviso that the total of components i), ii) and iii) equals 100% by weight, as solubilizers for slightly water-soluble substances.
摘要翻译：使用通过自由基聚合获得的共混物，i）30至80重量％的N-乙烯基内酰胺，ii）10至50重量％的乙酸乙烯酯，和iii）10至50重量％的聚醚，条件是组分i），ii）和iii）的总量等于100重量％，作为轻微水溶性物质的增溶剂。

5. 发明申请

US20080213361A1 Method for Production of Directly Compressible Ibuprofen Formulations 有权
标题翻译：生产直接可压缩布洛芬配方的方法
公开(公告)号：US20080213361A1
公开(公告)日：2008-09-04
申请号：US12089416
申请日：2006-10-05
申请人： Kathrin Meyer-Bohm , Karl Kolter , Anisul Quadir
发明人： Kathrin Meyer-Bohm , Karl Kolter , Anisul Quadir
IPC分类号： A61K9/20 , A61K31/192 , A61P29/00
CPC分类号： A61K31/192 , A61K9/1688 , A61K9/2009 , A61K9/2054 , A61K9/2095
摘要： A directly tabletable ibuprofen formulation comprising a) 50-99% by weight of crystalline ibuprofen, b) 1-15% by weight of a finely divided excipient with a surface area of at least 100 m2/g, and c) 0-40% by weight of further excipients, with the proviso that the total amount of components a) to c) corresponds to 100% by weight, where at least 50% of the surface of the ibuprofen crystals are covered with the finely divided excipient.
摘要翻译：一种可直接压片的布洛芬制剂，其包含a）50-99重量％的结晶布洛芬，b）1-15重量％的表面积至少为100微米/ ，和c）0-40重量％的其它赋形剂，条件是组分a）至c）的总量对应于100重量％，其中至少50％的布洛芬晶体的表面被覆盖精细分散的赋形剂。

6. 发明申请

US20080200564A1 Copolymers Based on N-Vinylpyrrolidone and Branched Aliphatic Carbonxylic Acids, and Their Use as Solubilizers 审中-公开
标题翻译：基于N-乙烯基吡咯烷酮和支链脂肪族羧酸的共聚物及其作为增溶剂的用途
公开(公告)号：US20080200564A1
公开(公告)日：2008-08-21
申请号：US11997208
申请日：2006-07-21
申请人： Maximilian Angel , Kathrin Meyer-Bohm
发明人： Maximilian Angel , Kathrin Meyer-Bohm
IPC分类号： A61K47/32
CPC分类号： C08F226/10 , C08F218/08 , C08F218/10 , C08F226/02
摘要： Copolymers comprising: (a) 60 to 99% by weight of at least one monomer selected from the group consisting of N-vinyllactams, N-vinylamides, and mixtures thereof; (1) 1 to 40% by weight of at least one monomer selected from the group consisting of vinyl esters of aliphatic branched C8-C30-carboxylic acids; (c) 0 to 30% by weight of vinyl acetate; and (d) 0 to 39% by weight of at least one additional free-radically copolymnerizable monomer; wherein the % by weight content of components (a), (b), (c) and (d) totals 100%, and with the proviso that the total amount of component (b) and component (c) combined is 1 to 40% by weight based on the copolymer, are described along with methods of using such copolymers to solubilize substances which are insoluble in water, substances which are only sparingly soluble in water, and combinations thereof.
摘要翻译：包括：（a）60至99重量％的至少一种选自N-乙烯基内酰胺，N-乙烯基酰胺及其混合物的单体; （1）1至40重量％的至少一种选自脂肪族支链C 8 -C 30 - 羧酸的乙烯基酯的单体; （c）0至30重量％的乙酸乙烯酯; 和（d）0至39重量％的至少一种另外的自由基共聚单体; 其中组分（a），（b），（c）和（d）的重量含量总计为100％，条件是组合物（b）和组分（c）的总量为1至40 基于共聚物的重量％以及使用这些共聚物溶解不溶于水的物质，仅微溶于水的物质及其组合的方法进行了描述。

7. 发明申请

US20090036551A1 COPOLYMERS BASED ON N-VINYL LACTAMS AND OLEFINS AS THEIR USE AS SOLUBILIZERS FOR SLIGHTLY WATER-SOLUBLE COMPOUNDS 审中-公开
标题翻译：基于N-乙烯酰胺和烯烃的共聚物作为其用于轻度水溶性化合物的溶解剂
公开(公告)号：US20090036551A1
公开(公告)日：2009-02-05
申请号：US12185329
申请日：2008-08-04
申请人： Rajan Venkatesh , Murat Mertoglu , Kathrin Meyer-Bohm
发明人： Rajan Venkatesh , Murat Mertoglu , Kathrin Meyer-Bohm
IPC分类号： A61K47/32 , A61K8/81
CPC分类号： C08F226/10 , C08F212/14 , C08F210/14
摘要： The use of copolymers obtained by free-radical polymerization of a mixture ofi) 0.1 to 40% by weight of an olefine, andii) 60 to 99.9% by weight of N-vinyl lactam,with the proviso that the total of components i), ii) and iii) equals 100% by weight, as solubilizers for slightly water-soluble bioactive substances.
摘要翻译：使用通过自由基聚合i）0.1至40重量％的烯烃和ii）60至99.9重量％的N-乙烯基内酰胺的共聚物获得的，条件是组分i ），ii）和iii）等于100重量％，作为轻微水溶性生物活性物质的增溶剂。

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