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1. 发明申请

US20070072270A1 Polypeptide 有权
公开(公告)号：US20070072270A1
公开(公告)日：2007-03-29
申请号：US11635511
申请日：2006-12-08
申请人： Karsten Kragh , Harm Mulder , Steffen Petersen , Helle Fomsgaard , Oene Veltman
发明人： Karsten Kragh , Harm Mulder , Steffen Petersen , Helle Fomsgaard , Oene Veltman
IPC分类号： C12N9/24 , C12P21/06 , C07H21/04 , C12N1/21 , C12N15/74
CPC分类号： A21D8/042 , A23K20/189 , A23L29/35 , C12N9/2417 , C12Y302/0106
摘要： We disclose a PS4 variant polypeptide derivable from a parent polypeptide, the parent polypeptide having non-maltogenic exoamylase activity, which PS4 variant polypeptide comprises one or more of the following substitutions: G69P, A141P, G223A, A268P, G313P, S399P and G400P, with reference to the position numbering of a Pseudomonas saccharophilia exoamylase sequence shown as SEQ ID NO: 1. Such PS4 variant polypeptides may be used as exo-amylases, particularly as non-maltogenic exoamylases. Combinations of such PS4 variant polypeptides together with Novamyl are disclosed.

2. 发明申请

US20050037391A1 Polypeptide 有权
标题翻译：多肽
公开(公告)号：US20050037391A1
公开(公告)日：2005-02-17
申请号：US10864874
申请日：2004-06-10
申请人： Karsten Kragh , Harm Mulder , Steffan Petersen , Helle Fomsgaard , Oene Robert Veltman
发明人： Karsten Kragh , Harm Mulder , Steffan Petersen , Helle Fomsgaard , Oene Robert Veltman
IPC分类号： A21D8/04 , A23K1/165 , A23L1/09 , C07H21/04 , C12N9/24 , C12N9/28 , C12N9/52 , C12N15/74 , C12Q1/68 , G01N33/554 , G01N33/569
CPC分类号： A21D8/042 , A23K20/189 , A23L29/35 , C12N9/2417 , C12Y302/0106
摘要： We disclose a PS4 variant polypeptide derivable from a parent polypeptide, the parent polypeptide having non-maltogenic exoamylase activity, which PS4 variant polypeptide comprises one or more of the following substitutions: G69P, A141P, G223A, A268P, G313P, S399P and G400P, with reference to the position numbering of a Pseudomonas saccharophilia exoamylase sequence shown as SEQ ID NO: 1. Such PS4 variant polypeptides may be used as exo-amylases, particularly as non-maltogenic exoamylases. Combinations of such PS4 variant polypeptides together with Novamyl are disclosed.
摘要翻译：我们公开了可从母体多肽衍生的PS4变体多肽，该亲本多肽具有非产麦芽糖外切酶活性，该PS4变体多肽包含一个或多个以下取代：G69P，A141P，G223A，A268P，G313P，S399P和G400P，具有提及如SEQ ID NO：1所示的假单胞菌糖酵母外切酶序列的位置编号。这样的PS4变体多肽可以用作外切淀粉酶，特别是作为非发酵的外消旋酶。公开了这些PS4变体多肽与Novamyl的组合。

3. 发明授权

US07858352B2 Polypeptide 有权
标题翻译：多肽
公开(公告)号：US07858352B2
公开(公告)日：2010-12-28
申请号：US11635511
申请日：2006-12-08
申请人： Karsten Matthias Kragh , Harm Mulder , Steffen Petersen , Helle Fomsgaard , Oene Robert Veltman
发明人： Karsten Matthias Kragh , Harm Mulder , Steffen Petersen , Helle Fomsgaard , Oene Robert Veltman
IPC分类号： C12N9/28 , C12N15/00 , C12N9/88
CPC分类号： A21D8/042 , A23K20/189 , A23L29/35 , C12N9/2417 , C12Y302/0106
摘要： We disclose a PS4 variant polypeptide derivable from a parent polypeptide, the parent polypeptide having non-maltogenic exoamylase activity, which PS4 variant polypeptide comprises one or more of the following substitutions: G69P, A141P, G223A, A268P, G313P, S399P and G400P, with reference to the position numbering of a Pseudomonas saccharophilia exoamylase sequence shown as SEQ ID NO: 1. Such PS4 variant polypeptides may be used as exo-amylases, particularly as non-maltogenic exoamylases. Combinations of such PS4 variant polypeptides together with Novamyl are disclosed.
摘要翻译：我们公开了可从母体多肽衍生的PS4变体多肽，该亲本多肽具有非产麦芽糖外切酶活性，该PS4变体多肽包含一个或多个以下取代：G69P，A141P，G223A，A268P，G313P，S399P和G400P，具有提及如SEQ ID NO：1所示的假单胞菌糖酵母外切酶序列的位置编号。这样的PS4变体多肽可以用作外切淀粉酶，特别是作为非发酵的外消旋酶。公开了这些PS4变体多肽与Novamyl的组合。

4. 发明授权

US07166453B2 Polypeptide 有权
标题翻译：多肽
公开(公告)号：US07166453B2
公开(公告)日：2007-01-23
申请号：US10864874
申请日：2004-06-10
申请人： Karsten Matthias Kragh , Harm Mulder , Steffen Petersen , Helle Fomsgaard , Oene Robert Veltman
发明人： Karsten Matthias Kragh , Harm Mulder , Steffen Petersen , Helle Fomsgaard , Oene Robert Veltman
IPC分类号： C12N9/28 , C12N15/00 , C12N9/88 , C07H21/04
CPC分类号： A21D8/042 , A23K20/189 , A23L29/35 , C12N9/2417 , C12Y302/0106
摘要： We disclose a PS4 variant polypeptide derivable from a parent polypeptide, the parent polypeptide having non-maltogenic exoamylase activity, which PS4 variant polypeptide comprises one or more of the following substitutions: G69P, A141P, G223A, A268P, G313P, S399P and G400P, with reference to the position numbering of a Pseudomonas saccharophilia exoamylase sequence shown as SEQ ID NO: 1. Such PS4 variant polypeptides may be used as exo-amylases, particularly as non-maltogenic exoamylases. Combinations of such PS4 variant polypeptides together with Novamyl are disclosed.
摘要翻译：我们公开了可从母体多肽衍生的PS4变体多肽，该亲本多肽具有非产麦芽糖外切酶活性，该PS4变体多肽包含一个或多个以下取代：G69P，A141P，G223A，A268P，G313P，S399P和G400P，具有提及如SEQ ID NO：1所示的假单胞菌糖酵母外切酶序列的位置编号。这样的PS4变体多肽可以用作外切淀粉酶，特别是作为非发酵的外消旋酶。公开了这些PS4变体多肽与Novamyl的组合。

5. 发明授权

US08791232B2 Proteins 有权
标题翻译：蛋白质
公开(公告)号：US08791232B2
公开(公告)日：2014-07-29
申请号：US12915204
申请日：2010-10-29
申请人： Patrick Maria Franciscus Derkx , Harm Mulder , Igor Nikolaev
发明人： Patrick Maria Franciscus Derkx , Harm Mulder , Igor Nikolaev
IPC分类号： C07K14/195 , C07K2/00
CPC分类号： C12N11/14 , C12N9/0006 , C12P19/00
摘要： An amino acid sequence is described. The amino acid may comprise a signal sequence that is SEQ ID NO. 1a (or a variant or homologue or derivative or fragment thereof) that is expressed as a fusion protein that comprises a protein of interest. The signal sequence directs secretion of the protein of interest. The protein of interest may be a heterologous protein. Secretion of the fusion protein aids purification.
摘要翻译：描述了氨基酸序列。氨基酸可以包含SEQ ID NO：1的信号序列。 1a（或其变体或同系物或其衍生物或片段），其表达为包含感兴趣的蛋白质的融合蛋白。信号序列指导目标蛋白的分泌。感兴趣的蛋白质可以是异源蛋白质。融合蛋白的分泌有助于净化。

6. 发明申请

US20100030875A1 Method and System For Remote Device Management 有权
标题翻译：远程设备管理方法与系统
公开(公告)号：US20100030875A1
公开(公告)日：2010-02-04
申请号：US12512242
申请日：2009-07-30
申请人： Robert Visser , Harm Mulder
发明人： Robert Visser , Harm Mulder
IPC分类号： G06F15/177 , G06F17/30 , G06F15/16
CPC分类号： H04L41/0813 , H04L29/12783 , H04L41/0206 , H04L41/0806 , H04L41/0856 , H04L61/35 , H04L67/16
摘要： A system for remote device management includes in a network an auto-configuration server managing device, at least one database, and a plurality of auto-configuration servers. The auto-configuration server managing device and the database are coupled in a communicative connection. The database holds information for identification of electronic devices. The auto-configuration server managing device is arranged for communication with a manageable electronic device over the network. The auto-configuration server manager is further being arranged for: receiving a request from the manageable electronic device for configuration data, determining an identification of the manageable electronic device by comparing the request with the information for identification of electronic devices of the database, determining an identification of an auto-configuration server from the plurality of auto-configuration servers in accordance with the identification of the manageable electronic device.
摘要翻译：用于远程设备管理的系统在网络中包括自动配置服务器管理设备，至少一个数据库和多个自动配置服务器。自动配置服务器管理设备和数据库以通信连接耦合。数据库保存电子设备识别信息。自动配置服务器管理设备被布置为通过网络与可管理的电子设备进行通信。自动配置服务器管理器进一步被安排为：从可管理电子设备接收用于配置数据的请求，通过将该请求与用于识别数据库的电子设备的信息进行比较来确定可管理电子设备的标识，根据可管理电子设备的识别，从多个自动配置服务器识别自动配置服务器。

7. 发明申请

US20110256571A1 PROTEINS 有权
标题翻译：蛋白质
公开(公告)号：US20110256571A1
公开(公告)日：2011-10-20
申请号：US12915204
申请日：2010-10-29
申请人： Patrick Maria Franciscus Derkx , Harm Mulder , Igor Nikolaev
发明人： Patrick Maria Franciscus Derkx , Harm Mulder , Igor Nikolaev
IPC分类号： C12P21/00 , C12N15/79 , C12N15/80 , C12N15/81 , C07H21/00 , C12N1/21 , C12N1/15 , C12N1/19 , C12Q1/02 , C07K14/00 , C12N15/63 , C12N1/00
CPC分类号： C12N11/14 , C12N9/0006 , C12P19/00
摘要： An amino acid sequence is described. The amino acid may comprise a signal sequence that is SEQ ID NO. 1a (or a variant or homologue or derivative or fragment thereof) that is expressed as a fusion protein that comprises a protein of interest. The signal sequence directs secretion of the protein of interest. The protein of interest may be a heterologous protein. Secretion of the fusion protein aids purification.
摘要翻译：描述了氨基酸序列。氨基酸可以包含SEQ ID NO：1的信号序列。 1a（或其变体或同系物或其衍生物或片段），其表达为包含感兴趣的蛋白质的融合蛋白。信号序列指导目标蛋白的分泌。感兴趣的蛋白质可以是异源蛋白质。融合蛋白的分泌有助于净化。

8. 发明申请

US20110236935A1 OXIDATION PROCESS 有权
标题翻译：氧化工艺
公开(公告)号：US20110236935A1
公开(公告)日：2011-09-29
申请号：US12915853
申请日：2010-10-29
申请人： Jørn Dalgaard Mikkelsen , Karsten Matthias Kragh , Rene Mikkelsen , Patrick Maria Franciscus Derkx , Shukun Yu , Harm Mulder , Igor Nikolaev
发明人： Jørn Dalgaard Mikkelsen , Karsten Matthias Kragh , Rene Mikkelsen , Patrick Maria Franciscus Derkx , Shukun Yu , Harm Mulder , Igor Nikolaev
IPC分类号： C12P19/04 , C12P19/00 , C12P19/12 , C12P19/10 , C08B37/16 , C08B31/18 , C08B37/00 , C12N9/04 , C12N15/53 , C12N15/63 , C12N1/21 , C12N1/15 , C12N1/19
CPC分类号： C12N11/14 , C12N9/0006 , C12P19/00
摘要： A method of oxidising a saccharide, by contacting the saccharide with an alcohol dehydrogenase (ADH) enzyme selected from a quinone redox cofactor-dependent ADH, a nicotinamide adenine dinucleotide (NAD+) redox cofactor-dependent ADH, a nicotinamide adenine dinucleotide phosphate (NADP+) redox cofactor-dependent ADH, and any combination thereof is described. An oxidised saccharide obtainable by the method and products, in particular food products and paper products, containing the oxidised saccharide, are also described.
摘要翻译：通过使糖与选自醌氧化还原辅因子ADH，烟酰胺腺嘌呤二核苷酸（NAD +）氧化还原辅因子依赖性ADH，烟酰胺腺嘌呤二核苷酸磷酸（NADP +）的NADP +）的醇脱氢酶（ADH）酶接触来进行氧化糖的方法，描述了氧化还原辅因子依赖性ADH及其任何组合。还描述了通过该方法获得的氧化糖，特别是含有氧化糖的食品和纸制品。

9. 发明授权

US08886772B2 Method and system for remote device management 有权
标题翻译：用于远程设备管理的方法和系统
公开(公告)号：US08886772B2
公开(公告)日：2014-11-11
申请号：US12512242
申请日：2009-07-30
申请人： Robert Visser , Harm Mulder
发明人： Robert Visser , Harm Mulder
IPC分类号： G06F15/177 , H04L12/24 , H04L29/12
CPC分类号： H04L41/0813 , H04L29/12783 , H04L41/0206 , H04L41/0806 , H04L41/0856 , H04L61/35 , H04L67/16
摘要： A system for remote device management includes in a network an auto-configuration server managing device, at least one database, and a plurality of auto-configuration servers. The auto-configuration server managing device and the database are coupled in a communicative connection. The database holds information for identification of electronic devices. The auto-configuration server managing device is arranged for communication with a manageable electronic device over the network. The auto-configuration server manager is further being arranged for: receiving a request from the manageable electronic device for configuration data, determining an identification of the manageable electronic device by comparing the request with the information for identification of electronic devices of the database, determining an identification of an auto-configuration server from the plurality of auto-configuration servers in accordance with the identification of the manageable electronic device.
摘要翻译：用于远程设备管理的系统在网络中包括自动配置服务器管理设备，至少一个数据库和多个自动配置服务器。自动配置服务器管理设备和数据库以通信连接耦合。数据库保存电子设备识别信息。自动配置服务器管理设备被布置为通过网络与可管理的电子设备进行通信。自动配置服务器管理器进一步被安排为：从可管理电子设备接收用于配置数据的请求，通过将该请求与用于识别数据库的电子设备的信息进行比较来确定可管理电子设备的标识，根据可管理电子设备的识别，从多个自动配置服务器识别自动配置服务器。

10. 发明授权

US08802398B2 Oxidation process 有权
标题翻译：氧化工艺
公开(公告)号：US08802398B2
公开(公告)日：2014-08-12
申请号：US12915853
申请日：2010-10-29
申请人： Jorn Dalgaard Mikkelsen , Karsten Matthias Kragh , Rene Mikkelsen , Patrick Maria Franciscus Derkx , Shukun Yu , Harm Mulder , Igor Nikolaev
发明人： Jorn Dalgaard Mikkelsen , Karsten Matthias Kragh , Rene Mikkelsen , Patrick Maria Franciscus Derkx , Shukun Yu , Harm Mulder , Igor Nikolaev
IPC分类号： C12P19/04 , C12P19/10 , C12P19/00 , C12N1/21 , C12N15/63
CPC分类号： C12N11/14 , C12N9/0006 , C12P19/00
摘要： A method of oxidizing a saccharide, by contacting the saccharide with an alcohol dehydrogenase (ADH) enzyme selected from a quinone redox cofactor-dependent ADH, a nicotinamide adenine dinucleotide (NAD+) redox cofactor-dependent ADH, a nicotinamide adenine dinucleotide phosphate (NADP+) redox cofactor-dependent ADH, and any combination thereof is described. An oxidized saccharide obtainable by the method and products, in particular food products and paper products, containing the oxidized saccharide, are also described.
摘要翻译：通过使糖类与选自醌氧化还原辅因子ADH，烟酰胺腺嘌呤二核苷酸（NAD +）氧化还原辅因子ADH，烟酰胺腺嘌呤二核苷酸磷酸（NADP +））的醇脱氢酶（ADH）酶接触来进行氧化糖的方法，描述了氧化还原辅因子依赖性ADH及其任何组合。还描述了通过该方法获得的氧化糖，特别是含有氧化糖的食品和纸制品。

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