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1. 发明申请

US20080132516A1 INDOLE, AZAINDOLE AND RELATED HETEROCYCLIC N-SUBSTITUTED PIPERAZINE DERIVATIVES 有权
标题翻译：吲哚，氮杂和相关杂环N-取代的哌嗪衍生物
公开(公告)号：US20080132516A1
公开(公告)日：2008-06-05
申请号：US12028189
申请日：2008-02-08
申请人： Kap-Sun Yeung , Michelle E. Farkas , John F. Kadow , Nicholas A. Meanwell , Malcolm Taylor , David Johnston , Thomas Stephen Coulter , J.J Kim Wright
发明人： Kap-Sun Yeung , Michelle E. Farkas , John F. Kadow , Nicholas A. Meanwell , Malcolm Taylor , David Johnston , Thomas Stephen Coulter , J.J Kim Wright
IPC分类号： A61K31/496 , C07D401/14 , A61P31/18
CPC分类号： C07D413/14 , C07D401/12 , C07D401/14 , C07D403/12 , C07D471/04 , C07D491/04
摘要： This invention provides compounds of Formula I, including pharmaceutically acceptable salts thereof, having drug and bio-affecting properties, their pharmaceutical compositions and method of use. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS. The compounds of Formula I have the formula wherein: Z is Q is selected from the group consisting of m is 2; A is selected from the group consisting of cinnolinyl, napthyridinyl, quinoxalinyl, pyridinyl, pyrimidinyl, quinolinyl, isoquinolinyl, quinazolinyl, azabenzofuryl, and phthalazinyl each of which may be optionally substituted with one or two groups independently selected from methyl, methoxy, hydroxy, amino and halogen; and —W— is
摘要翻译：本发明提供具有药物和生物影响性质的式I化合物，包括其药学上可接受的盐，其药物组合物和使用方法。这些化合物具有独特的抗病毒活性，无论是单独使用还是与其他抗病毒药，抗感染剂，免疫调节剂或HIV进入抑制剂组合使用。更具体地说，本发明涉及艾滋病毒和艾滋病的治疗。式I的化合物具有下式：其中：Z为Q选自m为2; A选自噌啉基，萘啶基，喹喔啉基，吡啶基，嘧啶基，喹啉基，异喹啉基，喹唑啉基，氮杂苯并呋喃基和酞嗪基，其各自可以任选被一个或两个独立地选自甲基，甲氧基，羟基，氨基和卤素; 和-W-是

2. 发明授权

US08039486B2 Indole, azaindole and related heterocyclic N-substituted piperazine derivatives 有权
标题翻译：吲哚，氮杂吲哚和相关杂环N-取代的哌嗪衍生物
公开(公告)号：US08039486B2
公开(公告)日：2011-10-18
申请号：US12028189
申请日：2008-02-08
申请人： Kap-Sun Yeung , Michelle E. Farkas , John F. Kadow , Nicholas A. Meanwell , Malcolm Taylor , David Johnston , Thomas Stephen Coulter , J. J. Kim Wright
发明人： Kap-Sun Yeung , Michelle E. Farkas , John F. Kadow , Nicholas A. Meanwell , Malcolm Taylor , David Johnston , Thomas Stephen Coulter , J. J. Kim Wright
IPC分类号： A61K31/04 , C07D215/38
CPC分类号： C07D413/14 , C07D401/12 , C07D401/14 , C07D403/12 , C07D471/04 , C07D491/04
摘要： This invention provides compounds of Formula I, including pharmaceutically acceptable salts thereof, having drug and bio-affecting properties, their pharmaceutical compositions and method of use. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS. The compounds of Formula I have the formula wherein: Z is Q is selected from the group consisting of m is 2; A is selected from the group consisting of cinnolinyl, napthyridinyl, quinoxalinyl, pyridinyl, pyrimidinyl, quinolinyl, isoquinolinyl, quinazolinyl, azabenzofuryl, and phthalazinyl each of which may be optionally substituted with one or two groups independently selected from methyl, methoxy, hydroxy, amino and halogen; and —W— is
摘要翻译：本发明提供具有药物和生物影响性质的式I化合物，包括其药学上可接受的盐，其药物组合物和使用方法。这些化合物具有独特的抗病毒活性，无论是单独使用还是与其他抗病毒药，抗感染剂，免疫调节剂或HIV进入抑制剂组合使用。更具体地说，本发明涉及艾滋病毒和艾滋病的治疗。式I的化合物具有下式：其中：Z为Q选自m为2; A选自噌啉基，萘啶基，喹喔啉基，吡啶基，嘧啶基，喹啉基，异喹啉基，喹唑啉基，氮杂苯并呋喃基和酞嗪基，其各自可以任选被一个或两个独立地选自甲基，甲氧基，羟基，氨基和卤素; 和-W-是

3. 发明申请

US20050261296A1 Indole, azaindole and related heterocyclic N-substituted piperazine derivatives 审中-公开
标题翻译：吲哚，氮杂吲哚和相关杂环N-取代的哌嗪衍生物
公开(公告)号：US20050261296A1
公开(公告)日：2005-11-24
申请号：US11029673
申请日：2005-01-05
申请人： Kap-Sun Yeung , Michelle Farkas , John Kadow , Nicholas Meanwell , Malcolm Taylor , David Johnston , Thomas Coulter , J. Wright
发明人： Kap-Sun Yeung , Michelle Farkas , John Kadow , Nicholas Meanwell , Malcolm Taylor , David Johnston , Thomas Coulter , J. Wright
IPC分类号： A61K31/405 , A61K31/4745 , A61K31/496 , A61K31/497 , A61K31/498 , A61K31/502 , A61K31/517 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D413/14 , C07D471/02 , C07D471/04 , C07D487/04 , C07D491/04 , C07D43/14
CPC分类号： C07D413/14 , C07D401/12 , C07D401/14 , C07D403/12 , C07D471/04 , C07D491/04
摘要： This invention provides compounds of Formula I, including pharmaceutically accceptable salts thereof, having drug and bio-affecting properties, their pharmaceutical compositions and method of use. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS. The compounds of Formula I have the formula wherein: Z is Q is selected from the group consisting of m is 2; A is selected from the group consisting of cinnolinyl, napthyridinyl, quinoxalinyl, pyridinyl, pyrimidinyl, quinolinyl, isoquinolinyl, quinazolinyl, azabenzofuryl, and phthalazinyl each of which may be optionally substituted with one or two groups independently selected from methyl, methoxy, hydroxy, amino and halogen; and —W— is
摘要翻译：本发明提供具有药物和生物影响性质的式I化合物，包括其药学上可接受的盐，其药物组合物和使用方法。这些化合物具有独特的抗病毒活性，无论是单独使用还是与其他抗病毒药，抗感染剂，免疫调节剂或HIV进入抑制剂组合使用。更具体地说，本发明涉及艾滋病毒和艾滋病的治疗。式I的化合物具有下式：其中：Z为Q选自m为2; A选自噌啉基，萘啶基，喹喔啉基，吡啶基，嘧啶基，喹啉基，异喹啉基，喹唑啉基，氮杂苯并呋喃基和酞嗪基，其各自可以任选被一个或两个独立地选自甲基，甲氧基，羟基，氨基和卤素; 和-W-是

4. 发明申请

US20050075364A1 Indole, azaindole and related heterocyclic N-substituted piperazine derivatives 审中-公开
公开(公告)号：US20050075364A1
公开(公告)日：2005-04-07
申请号：US10871931
申请日：2004-06-18
申请人： Kap-Sun Yeung , Michelle Farkas , John Kadow , Nicholas Meanwell , Malcolm Taylor , David Johnston , Thomas Coulter , J. J. Wright
发明人： Kap-Sun Yeung , Michelle Farkas , John Kadow , Nicholas Meanwell , Malcolm Taylor , David Johnston , Thomas Coulter , J. J. Wright
IPC分类号： A61K31/405 , A61K31/4745 , A61K31/496 , A61K31/497 , A61K31/498 , A61K31/502 , A61K31/517 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D413/14 , C07D471/02 , C07D471/04 , C07D487/04 , C07D491/04
CPC分类号： C07D413/14 , C07D401/12 , C07D401/14 , C07D403/12 , C07D471/04 , C07D491/04
摘要： This invention provides compounds of Formula I, including pharmaceutically accceptable salts thereof, having drug and bio-affecting properties, their pharmaceutical compositions and method of use. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS. The compounds of Formula I have the formula wherein: Z is Q is selected from the group consisting of m is 2; A is selected from the group consisting of cinnolinyl, napthyridinyl, quinoxalinyl, pyridinyl, pyrimidinyl, quinolinyl, isoquinolinyl, quinazolinyl, azabenzofuryl, and phthalazinyl each of which may be optionally substituted with one or two groups independently selected from methyl, methoxy, hydroxy, amino and halogen; and —W— is

5. 发明申请

US20200230790A1 Color-Coded Method for Combination Wrenches 审中-公开
公开(公告)号：US20200230790A1
公开(公告)日：2020-07-23
申请号：US16250083
申请日：2019-01-17
申请人： Pedro Rincon , David Johnston
发明人： Pedro Rincon , David Johnston
IPC分类号： B25B23/16
摘要： The combination key sets in mm fabrication are identified by a single color and SAE (American Standard) with a different color. Each Key has been printed in the number corresponding to the size of the logo with a different color for each color code. The Ratchet combination Key has an arrow and the numbers go in the same direction indicating the direction in which it should be used. On one side are green to tighten and on the other are red to loosen. Additionally, each key set has protective coverings that are also matched and coordinated by colors.

6. 发明授权

US09544139B2 Method and apparatus for a non-deterministic random bit generator (NRBG) 有权
标题翻译：用于非确定性随机位发生器（NRBG）的方法和装置
公开(公告)号：US09544139B2
公开(公告)日：2017-01-10
申请号：US13976175
申请日：2011-12-29
申请人： George W. Cox , David Johnston , Martin G. Dixon , Stephen A. Fischer , Jason W. Brandt
发明人： George W. Cox , David Johnston , Martin G. Dixon , Stephen A. Fischer , Jason W. Brandt
IPC分类号： H04L9/00 , H04L9/08 , H04L9/06 , G06F7/58 , G06F9/30 , G06F15/16
CPC分类号： H04L9/0869 , G06F7/588 , G06F9/30007 , H04L9/0662 , H04L2209/24
摘要： A hardware-based digital random number generator is provided. In one embodiment, a processor includes a digital random number generator (DRNG) to condition entropy data provided by an entropy source, to generate a plurality of deterministic random bit (DRB) strings, and to generate a plurality of nondeterministic random bit (NRB) strings, and an execution unit coupled to the DRNG, in response to a first instruction to read a seed value, to retrieve one of the NRB strings from the DRNG and to store the NRB string in a destination register specified by the first instruction.
摘要翻译：提供了一种基于硬件的数字随机数发生器。在一个实施例中，处理器包括数字随机数发生器（DRNG），用于对熵源提供的熵数据进行条件生成，以产生多个确定性随机位（DRB）串，并产生多个非确定性随机位（NRB）响应于读取种子值的第一指令，从DRNG检索NRB字符串中的一个并将NRB字符串存储在由第一指令指定的目的地寄存器中，耦合到DRNG的执行单元。

7. 发明申请

US20140095867A1 DEVICE, METHOD, AND SYSTEM FOR SECURE TRUST ANCHOR PROVISIONING AND PROTECTION USING TAMPER-RESISTANT HARDWARE 有权
标题翻译：使用防潮硬件安全信赖锚定器和保护的装置，方法和系统
公开(公告)号：US20140095867A1
公开(公告)日：2014-04-03
申请号：US13631562
申请日：2012-09-28
申请人： Ned M. Smith , David Johnston , George W. Cox , Adi Shaliv
发明人： Ned M. Smith , David Johnston , George W. Cox , Adi Shaliv
IPC分类号： H04L29/06 , H04L9/32 , G06F17/30 , H04L9/00 , H04L9/08
CPC分类号： H04L63/061 , H04L9/0822 , H04L9/0866 , H04L9/3231 , H04L63/0861 , H04L2209/127
摘要： A method and device for securely provisioning trust anchors includes generating a database wrapper key as a function of computing device hardware. The database wrapper key encrypts a key database when it is not in use by a trusted execution environment and may be generated using a Physical Unclonable Function (PUF). A local computing device establishes a secure connection and security protocols with a remote computing device. In establishing the secure connection, the local computing device and remote computing device may exchange and/or authenticate cryptographic keys, including Enhanced Privacy Identification (EPID) keys, and establish a session key and device identifier(s). One or more trust anchors are then provisioned depending on whether unilateral, bilateral, or multilateral trust is established. The local computing device may act as a group or domain controller in establishing multilateral trust. Any of the devices may also require user presence to be verified.
摘要翻译：用于安全地配置信任锚的方法和设备包括生成作为计算设备硬件的函数的数据库包装密钥。数据库包装器密钥在密钥数据库不被可信执行环境使用时加密，并且可以使用物理不可克隆功能（PUF）生成密钥数据库。本地计算设备与远程计算设备建立安全连接和安全协议。在建立安全连接时，本地计算设备和远程计算设备可以交换和/或验证密码密钥，包括增强型隐私标识（EPID）密钥，并建立会话密钥和设备标识符。根据单方面，双边或多边信托是否建立了一个或多个信托基金。本地计算设备可以充当组或域控制器来建立多边信任。任何设备也可能要求验证用户存在。

8. 发明申请

US20140032933A1 PROVIDING ACCESS TO ENCRYPTED DATA 审中-公开
标题翻译：提供访问加密数据
公开(公告)号：US20140032933A1
公开(公告)日：2014-01-30
申请号：US13557079
申请日：2012-07-24
申请人： Ned M. Smith , George W. Cox , David Johnston
发明人： Ned M. Smith , George W. Cox , David Johnston
IPC分类号： G06F21/24
CPC分类号： H04L9/0866 , G06F21/31 , G06F21/6209 , G06F21/74 , G06F2221/2107 , H04L9/0822 , H04L9/3226
摘要： Embodiments of methods, systems, and storage medium associated with providing access to encrypted data for authorized users are disclosed herein. In one instance, the method may include obtaining a derived value for an authenticated user based on user personalization data of the authenticated user, and generating a user-specific encryption key based on the derived value. The derived value may have entropy in excess of a predetermined level. The user-specific encryption key may enable the authenticated user to access the encrypted data stored at the storage device. Other embodiments may be described and/or claimed.
摘要翻译：这里公开了与为授权用户提供对加密数据的访问相关联的方法，系统和存储介质的实施例。在一个实例中，该方法可以包括基于认证用户的用户个性化数据获得经认证的用户的导出值，并且基于导出的值生成用户特定加密密钥。导出值可能具有超过预定水平的熵。用户专用加密密钥可以使经认证的用户能够访问存储在存储设备上的加密数据。可以描述和/或要求保护其他实施例。

9. 发明授权

US08489660B2 Digital random number generator using partially entropic data 有权
标题翻译：使用部分熵数据的数字随机数发生器
公开(公告)号：US08489660B2
公开(公告)日：2013-07-16
申请号：US12459142
申请日：2009-06-26
申请人： Howard C. Herbert , George W. Cox , Shay Gueron , Jesse Walker , Charles E. Dike , Stephen A. Fischer , Ernie Brickell , Martin G. Dixon , David Johnston , Gunendran Thuraisingham , Edward V. Gamsaragan , James S. Coke , Greg W. Piper
发明人： Howard C. Herbert , George W. Cox , Shay Gueron , Jesse Walker , Charles E. Dike , Stephen A. Fischer , Ernie Brickell , Martin G. Dixon , David Johnston , Gunendran Thuraisingham , Edward V. Gamsaragan , James S. Coke , Greg W. Piper
IPC分类号： G06F7/58
CPC分类号： G06F7/588 , G06F9/30007 , H04L9/0861
摘要： A hardware-based digital random number generator is provided. The digital random number generator is a randomly behaving random number generator based on a set of nondeterministic behaviors. The nondeterministic behaviors include temporal asynchrony between subunits, entropy source “extra” bits, entropy measurement, autonomous deterministic random bit generator reseeding and consumption from a shared resource.
摘要翻译：提供了一种基于硬件的数字随机数发生器。数字随机数发生器是基于一组非确定性行为的随机行为随机数发生器。非确定性行为包括子单元之间的时间不同步，熵源“额外”比特，熵测量，自主确定性随机比特生成器重新获取和来自共享资源的消费。

10. 发明授权

US08375205B2 Techniques for communicating information over management channels 失效
标题翻译：通过管理渠道传达信息的技术
公开(公告)号：US08375205B2
公开(公告)日：2013-02-12
申请号：US11864123
申请日：2007-09-28
申请人： David Johnston
发明人： David Johnston
IPC分类号： H04L29/06
CPC分类号： H04W12/02 , H04L63/0428 , H04L63/105 , H04L63/162 , H04W8/00 , H04W80/02 , H04W84/12
摘要： Techniques for communicating information over management channels are described. An apparatus may comprise a classifier module operative to classify management information for a wireless communications network as media access control security management information or media access control management information. The apparatus may further comprise a wireless transceiver to couple to the classifier module, the wireless transceiver operative to communicate the media access control security management information over an insecure management connection and the media access control management information over a secure management connection. Other embodiments are described and claimed.
摘要翻译：描述了通过管理通道传递信息的技术。装置可以包括分类器模块，用于将无线通信网络的管理信息分类为媒体访问控制安全管理信息或媒体访问控制管理信息。该装置还可以包括无线收发器以耦合到分类器模块，无线收发器可操作以通过不安全的管理连接传送媒体访问控制安全管理信息，并通过安全管理连接传送媒体访问控制管理信息。描述和要求保护其他实施例。

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