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    • 1. 发明授权
    • Method of preparing iodine seed for treating eye disease or cancer, and iodine seed prepared thereby
    • 制备碘晶种治疗眼病或癌症的方法及由此制备的碘种子
    • US09421282B2
    • 2016-08-23
    • US13765072
    • 2013-02-12
    • Kang Hyuk ChoiKwang Jae SonJin-Hee LeeSung-Soo NamSun Ju Choi
    • Kang Hyuk ChoiKwang Jae SonJin-Hee LeeSung-Soo NamSun Ju Choi
    • A61M36/14A61K51/00A61K51/02A61K51/12
    • A61K51/00A61K51/02A61K51/1282
    • The present invention provides a technique for adsorbing I-125 on a support for treating cancer and a method of preparing an I-125 seed using the same. Since a method of preparing iodine according to the present invention uses an intermediate having phosphate-based, oxalate-based, or arsenate-based anions introduced thereinto, the intermediate has a substitution effect of iodine 3 to 5 times higher than that of a typically used intermediate having chlorine anions introduced thereinto. According to the substitution effect, control of a radiation dose may be possible during the manufacturing of an iodine seed and an iodine seed may be prepared within a shorter period of time. Also, since an amount of residual radioactive iodine may be decreased as a result of a large amount of adsorption, an amount of radioactive iodine (I-125) waste may be decreased, and the effect thereof may be also high environmentally.
    • 本发明提供了用于将I-125吸附在用于治疗癌症的支持体上的技术,以及使用该技术制备I-125种子的方法。 由于根据本发明的制备碘的方法使用引入其中含有基于磷酸盐,草酸盐或砷酸盐的阴离子的中间体,所以中间体具有碘的替代效应,比通常使用的碘的比例高3至5倍 带有氯阴离子的中间体。 根据替代效果,在制造碘种子期间可以控制辐射剂量,并且可以在更短的时间内制备碘种子。 另外,由于吸附量大,残留的放射性碘量可能会降低,因此放射性碘(I-125)废物的量可能会降低,其效果也可能较高。