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1. 发明申请

US20190197674A1 FEATURE-BASED IMAGE PROCESSING USING FEATURE IMAGES EXTRACTED FROM DIFFERENT ITERATIONS 审中-公开
公开(公告)号：US20190197674A1
公开(公告)日：2019-06-27
申请号：US16325213
申请日：2017-08-22
申请人： KONINKLIJKE PHILIPS N.V.
发明人： Chuanyong BAI , Andriy ANDREYEV , Bin ZHANG , Yang-Ming ZHU , Xiyun SONG , Jinghan YE , Zhiqiang HU
IPC分类号： G06T5/50 , G06T11/00 , G06K9/62
CPC分类号： G06T5/50 , G06K9/6232 , G06T11/006 , G06T11/008 , G06T2207/10104 , G06T2207/10108 , G06T2207/20221 , G06T2207/20224 , G06T2211/424
摘要： Image processing performed by a computer (22) includes iterative image reconstruction or refinement (26, 56) that produces a series of update images ending in an iteratively reconstructed or refined image. A difference image (34, 64) is computed between a first update image (30, 60) and a second update image (32, 62) of the series. The difference image is converted to a feature image (40) and is used in the iterative processing (26, 56) or in post-processing (44) performed on the iteratively reconstructed or refined images or images from different reconstruction or refinement techniques. In another embodiment, first and second image reconstructions (81, 83) are performed to generate respective first and second reconstructed images (80, 82). A difference image (84) is computed between two images each selected from the group: the first reconstructed image, an update image of the first reconstruction, the second reconstructed image, and an update image of the second reconstruction. A feature image is generated from the difference image and used to combine the first and second reconstructed images.

2. 发明申请

US20200301030A1 SHORT LEADING AND TRAILING FRAMES TO IMPROVE IMAGE QUALITY IN POSITRON EMISSION TOMOGRPAHY (PET) 审中-公开
公开(公告)号：US20200301030A1
公开(公告)日：2020-09-24
申请号：US16763457
申请日：2018-11-06
申请人： KONINKLIJKE PHILIPS N.V.
发明人： Andriy ANDREYEV , Chuanyong BAI , Xiyun SONG , Jinghan YE
IPC分类号： G01T1/29 , A61B6/00 , A61B6/03
摘要： A non-transitory computer-readable medium storing instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an image reconstruction method (100). The method includes: receiving a surview image of a target anatomy acquired by an image acquisition device (12); selecting an axial field of view (FOV) of an imaging volume using the received surview image; optimizing axial boundaries of leading and trailing frames respective to the selected axial FOV of the imaging volume; operating a positron emission tomography (PET) imaging device (14) to acquire PET imaging data including acquiring PET imaging data for the leading frame followed by acquiring PET imaging data for the imaging volume followed by acquiring PET imaging data for the trailing frame; and reconstructing the PET imaging data to generate an image of the selected imaging volume including out-of-axial FOV scatter correction performed using the PET imaging data acquired for at least one of the leading and trailing frames.

3. 发明申请

US20200294285A1 RECONSTRUCTING IMAGES FOR A WHOLE BODY POSITRON EMISSION TOMOGRAPY (PET) SCAN WITH OVERLAP AND VARYING EXPOSURE TIME FOR INDIVIDUAL BED POSITIONS 审中-公开
公开(公告)号：US20200294285A1
公开(公告)日：2020-09-17
申请号：US16758005
申请日：2018-10-19
申请人： KONINKLIJKE PHILIPS N.V.
发明人： Xiyun SONG , Andriy ANDREYEV , Chuanyong BAI , Jinghan YE , Chi-Hua TUNG , Bin ZHANG , Xiangyu WU , Changhong DAI , Tianrui GUO , Zhiqiang HU
IPC分类号： G06T11/00 , G06T5/50 , G01T1/29
摘要： A non-transitory computer-readable medium stores instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an image reconstruction method (100). The method includes: operating a positron emission tomography (PET) imaging device (12) to acquire imaging data on a frame by frame basis for frames along an axial direction with neighboring frames overlapping along the axial direction wherein the frames include a frame (k), a preceding frame (k−1) overlapping the frame (k), and a succeeding frame (k+1) overlapping the frame (k); reconstructing an image of the frame (k) using imaging data from the frame (k), the preceding frame (k−1), and the succeeding frame (k+1).

4. 发明申请

US20170046857A1 PET RANDOM COINCIDENCE CORRECTION 审中-公开
标题翻译： PET随机梳理校正
公开(公告)号：US20170046857A1
公开(公告)日：2017-02-16
申请号：US15304538
申请日：2015-04-23
申请人： KONINKLIJKE PHILIPS N.V.
发明人： Jinghan YE , Xiyun SONG
IPC分类号： G06T11/00 , G06T3/40 , G06T7/00
CPC分类号： G06T11/005 , G06T3/40 , G06T7/0012 , G06T2207/10104 , G06T2207/30242
摘要： A positron emission tomography (PET) imaging system (10) includes a singles unit (24), a delay unit (26), a scaling unit (28), and a reconstruction unit (30). The singles unit (24) is configured to generate a correction sinogram of random coincidences defined by a coincidence time window tw and a time period t based on rij=2 t si sj where rij is an estimate of the random coincidences in the time period t between singles at detector locations si and sj. The delay unit (26) is configured to determine delay coincidences in the time period t defined by a delay coincidence time window of a paired coincidences including tw to 2 tw. The scaling unit (28) is configured to scale the correction sinogram of random coincidences based on the delay coincidences. The reconstruction unit (30) is configured to iteratively reconstruct one or more images based on the scaled random sinogram and a prompt sinogram for the time period t.
摘要翻译：正电子发射断层摄影（PET）成像系统（10）包括单打单元（24），延迟单元（26），缩放单元（28）和重建单元（30）。单位单元（24）被配置为生成基于rij = 2t si sj的符合时间窗tw和时间段t所定义的随机重合的校正正弦图，其中rij是时间段t内的随机重合的估计在检测器位置si和sj处的单个之间。延迟单元（26）被配置为确定由包括tw至2 tw的成对重合的延迟符合时间窗口定义的时间段t中的延迟重合。缩放单元（28）被配置为基于延迟重合来缩放随机重合的校正中心图。重建单元（30）被配置为基于缩放的随机正弦图和时间段t的提示正弦曲线迭代地重构一个或多个图像。

5. 发明申请

US20210375009A1 SCATTER CORRECTION FOR POSITRON EMISSION TOMOGRAPHY (PET) 有权
公开(公告)号：US20210375009A1
公开(公告)日：2021-12-02
申请号：US16963343
申请日：2019-01-24
申请人： KONINKLIJKE PHILIPS N.V.
发明人： Jinghan YE , Xiyun SONG , Chuanyong BAI , Andriy ANDREYEV , Chi-Hua TUNG , Zhiqiang HU
IPC分类号： G06T11/00
摘要： A non-transitory computer-readable medium stores instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an image reconstruction method (100). The method includes: generating, from received imaging data, a plurality of intermediate images reconstructed without scatter correction from data partitioned into different energy windows; generating a fraction of true counts and a fraction of scatter events in the generated intermediate images; generating a final reconstructed image from the intermediate images, the fraction of true counts in the intermediate images, and the fraction of scatter counts in the intermediate images; and at least one of controlling the non-transitory computer readable medium to store the final image and control a display device (24) to display the final image.

6. 发明申请

US20210209817A1 OPTIMIZATION-BASED RECONSTRUCTION WITH AN IMAGE-TOTAL-VARIATION CONSTRAINT IN PET 有权
公开(公告)号：US20210209817A1
公开(公告)日：2021-07-08
申请号：US16070791
申请日：2017-02-13
申请人： KONINKLIJKE PHILIPS N.V. , UNIVERSITY OF CHICAGO
发明人： Xiaochuan PAN , Jinghan YE , Amy PERKINS , Chi-Hua TUNG , Zheng ZHANG
IPC分类号： G06T11/00 , A61B6/03 , A61B6/00
摘要： In an emission imaging method, emission imaging data are acquired for a subject using an emission imaging scanner (10) including radiation detectors (12). The emission imaging data are reconstructed to generate a reconstructed image by executing a constrained optimization program including a measure of data fidelity between the acquired emission imaging data an a reconstruct-image transformed by a data model of the imaging scanner to emission imaging data. During the reconstructing, each iteration of the constrained optimization program is constrained by an image variability constraint. The reconstructed image is displayed the reconstructed image on a display device. The emission imaging may be positron emission tomography (PET) imaging data, optionally acquired using a sparse detector array. The image variability constraint may be a constraint that an image total variation (image TV) of a latent image defined using a Gaussian blurring matrix be less than a maximum value.

7. 发明申请

US20190361136A1 DEAD PIXEL CORRECTION FOR DIGITAL PET RECONSTRUCTION 审中-公开
公开(公告)号：US20190361136A1
公开(公告)日：2019-11-28
申请号：US16469605
申请日：2017-12-06
申请人： KONINKLIJKE PHILIPS N.V.
发明人： Xiyun SONG , Chuanyong BAI , Andriy ANDREYEV , Bin ZHANG , Sushen LIN , Jinghan YE , Michael Allen MILLER , Zhiqiang HU
IPC分类号： G01T1/29 , G01T7/00 , G06T5/00 , A61B6/03 , A61B6/00 , G01T1/24
摘要： A PET detector array (8) comprising detector pixels acquires PET detection counts along lines of response (LORs). The counts are reconstructed to generate a reconstructed PET image (36, 46). The reconstructing is corrected for missing LORs which are missing due to dead detector pixels of the PET detector array. The correction may be by estimating counts along the missing LORs (60) by interpolating counts along LORs (66) neighboring the missing LORs. The interpolation may be iterative to handle contiguous groups of missing detector pixels. The correction may be by computing a sensitivity matrix having matrix elements corresponding to image elements (80, 82) of the reconstructed PET image. In this case, each matrix element is computed as a summation over all LORs intersecting the corresponding image element excepting the missing LORs. The computed sensitivity matrix is used in the reconstructing.

8. 发明申请

US20200093452A1 IMAGE-ASSISTED AUTOMATIC PATIENT POSITINING FOR IMPROVED IMAGING PERFORMANCE 审中-公开
公开(公告)号：US20200093452A1
公开(公告)日：2020-03-26
申请号：US16471655
申请日：2017-12-20
申请人： KONINKLIJKE PHILIPS N.V.
发明人： Chuanyong BAI , Andriy ANDREYEV , Yanfei MAO , Bin ZHANG , Xiyun SONG , Jinghan YE , Shekhar DWIVEDI , Zhiqiang HU
IPC分类号： A61B6/00 , A61B6/03 , A61B6/04
摘要： An imaging apparatus includes a nuclear medicine imaging device (10), a patient table (14), and a table controller (18) comprising an electronic processor and actuators configured to position the patient table along an axial direction and in a transverse plane that is transverse to the axial direction. An automatic positioning engine (40) comprises an electronic processor (42) programmed to determine an optimal position of the patient table in the transverse plane for imaging a target of interest in a patient based on a prior image (20, 34) of the patient. The table controller operates the patient table to position the patient table in accord with the determined optimal position of the patient table.

9. 发明申请

US20190339403A1 TIME-OF-FLIGHT RESOLUTION-ADAPTIVE IMAGE REGULARIZATION AND FILTERING IN POSITRON EMISSION TOMOGRAPHY 审中-公开
公开(公告)号：US20190339403A1
公开(公告)日：2019-11-07
申请号：US16470730
申请日：2017-12-18
申请人： KONINKLIJKE PHILIPS N.V.
发明人： Chuanyong BAI , Andriy ANDREYEV , Andre Frank SALOMON , Andreas GOEDICKE , Jinghan YE , Yu-Lung HSIEH , Bin ZHANG , Xiyun SONG , Manoj NARAYANAN , Zhiqiang HU
IPC分类号： G01T1/29
摘要： A time of flight (TOF) positron emission tomography (PET) image (38) is generated from TOF PET imaging data (10) acquired of a subject using a TOF PET imaging data acquisition device (6). Iterative image reconstruction (30) of the TOF PET imaging data is performed with TOF localization of counts along respective lines of response (LORs) to iteratively update a reconstructed image (32). Values for at least one regularization or filtering parameter are assigned to the TOF PET imaging data or to voxels of the reconstructed image based on an estimated TOF localization resolution for the TOF PET imaging data or voxels. Regularization (34) or filtering (36) of the reconstructed image is performed using the assigned values for the at least one regularization or filtering parameter. In some embodiments, the varying TOF localization resolution for the TOF PET imaging data or voxels is estimated based on related N acquisition characteristics such as count rates or operating temperature of the detectors.

10. 发明申请

US20180021009A1 PET DETECTOR TIMING CALIBRATION 有权
公开(公告)号：US20180021009A1
公开(公告)日：2018-01-25
申请号：US15520898
申请日：2015-10-15
申请人： KONINKLIJKE PHILIPS N.V.
发明人： Jinghan YE , Xiyun SONG , Thomas Leroy LAURENCE , Sharon Xiaorong WANG
IPC分类号： A61B6/00 , A61B6/03
CPC分类号： A61B6/583 , A61B6/037 , A61B6/4266 , G01T1/2985
摘要： A diagnostic imaging system comprises a plurality of radiation detectors (20) configured to detect radiation events emanating from an imaging region. The system comprises a calibration phantom (14) configured to be disposed in the imaging region spanning substantially an entire field of view and to generate radiation event pairs that define lines-of-response, wherein the calibration phantom is thin such that each LOR intersects the calibration phantom along its length, the thickness of the phantom being smaller than the length of the LORs. A calibration processor (24) receives input of the radiation detectors and calculates an incidence angle independent crystal delay τi for each detector. The calibration processor (24) constructs a first look-up table for the timing correction of each LOR and a second look-up table for the angle depth of interaction correction for each crystal by combining τi and ηi

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