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1. 发明授权

US10220060B2 Agent for inducing interferon production containing lactic acid bacteria 有权
公开(公告)号：US10220060B2
公开(公告)日：2019-03-05
申请号：US15367649
申请日：2016-12-02
申请人： KIRIN HOLDINGS KABUSHIKI KAISHA
发明人： Daisuke Fujiwara , Kenta Jonai , Tetsu Sugimura
IPC分类号： A61K35/744 , A23C19/06 , A23C9/123 , A61K35/747 , C12N1/20 , A61K31/711 , C12N15/74 , C12Q1/6809 , G01N33/68 , A23C19/032 , A23L33/135 , A61K9/00 , C12R1/01
摘要： This invention provides an IFN inducer comprising, as an active ingredient, lactic acid bacteria and capable of inducing IFN production, an immunopotentiating agent or prophylactic agent against virus infection comprising such inducer, and a food or drink product comprising such IFN inducer and having IFN-inducing activity, immunopotentiating activity, or prophylactic activity against virus infection. The agent for inducing IFN production comprises, as active ingredients, lactic acid bacteria that can activate plasmacytoid dendritic cells (pDCs) and promote IFN production, such as Lactococcus garvieae NBRC100934, Lactococcus lactis subsp. cremoris JCM16167, Lactococcus lactis subsp. cremoris NBRC100676, Lactococcus lactis subsp. hordniae JCM1180, Lactococcus lactis subsp. hordniae JCM11040, Lactococcus lactis subsp. lactis NBRC12007, Lactococcus lactis subsp. lactis NRIC1150, Lactococcus lactis subsp. lactis JCM5805, Lactococcus lactis subsp. lactis JCM20101, Leuconostoc lactis NBRC12455, Leuconostoc lactis NRIC1540, Pediococcus damnosus JCM5886, or Streptococcus thermophilus TA-45.

2. 发明授权

US11224623B2 Agent for inducing interferon production containing lactic acid bacteria 有权
公开(公告)号：US11224623B2
公开(公告)日：2022-01-18
申请号：US16290581
申请日：2019-03-01
申请人： KIRIN HOLDINGS KABUSHIKI KAISHA
发明人： Daisuke Fujiwara , Kenta Jonai , Tetsu Sugimura
IPC分类号： A61K35/744 , A23L33/135 , A23C9/123 , A61K35/747 , C12N1/20 , A23C19/032 , A23C19/06 , A61K31/711 , C12N15/74 , C12Q1/6809 , G01N33/68 , A61K9/00 , C12R1/01
摘要： This invention provides an IFN inducer comprising, as an active ingredient, lactic acid bacteria and capable of inducing IFN production, an immunopotentiating agent or prophylactic agent against virus infection comprising such inducer, and a food or drink product comprising such IFN inducer and having IFN-inducing activity, immunopotentiating activity, or prophylactic activity against virus infection. The agent for inducing IFN production comprises, as active ingredients, lactic acid bacteria that can activate plasmacytoid dendritic cells (pDCs) and promote IFN production, such as Lactococcus garvieae NBRC100934, Lactococcus lactis subsp. cremoris JCM16167, Lactococcus lactis subsp. cremoris NBRC100676, Lactococcus lactis subsp. hordniae JCM1180, Lactococcus lactis subsp. hordniae JCM11040, Lactococcus lactis subsp. lactis NBRC12007, Lactococcus lactis subsp. lactis NRIC1150, Lactococcus lactis subsp. lactis JCM5805, Lactococcus lactis subsp. lactis JCM20101, Leuconostoc lactis NBRC12455, Leuconostoc lactis NRIC1540, Pediococcus damnosus JCM5886, or Streptococcus thermophilus TA-45.

3. 发明申请

US20190192584A1 AGENT FOR INDUCING INTERFERON PRODUCTION CONTAINING LACTIC ACID BACTERIA 审中-公开
公开(公告)号：US20190192584A1
公开(公告)日：2019-06-27
申请号：US16290581
申请日：2019-03-01
申请人： KIRIN HOLDINGS KABUSHIKI KAISHA
发明人： Daisuke FUJIWARA , Kenta Jonai , Tetsu Sugimura
IPC分类号： A61K35/744 , A23L33/135 , A23C19/032 , A23C9/123 , G01N33/68 , A61K35/747 , A61K31/711 , C12Q1/6809 , C12N15/74 , A23C19/06 , C12R1/01 , A61K9/00 , C12N1/20
CPC分类号： A61K35/744 , A23C9/123 , A23C9/1236 , A23C19/0323 , A23C19/062 , A23L33/135 , A23Y2240/41 , A61K9/0053 , A61K31/711 , A61K35/747 , C12N1/20 , C12N15/746 , C12Q1/6809 , C12R1/01 , G01N33/6866
摘要： This invention provides an IFN inducer comprising, as an active ingredient, lactic acid bacteria and capable of inducing IFN production, an immunopotentiating agent or prophylactic agent against virus infection comprising such inducer, and a food or drink product comprising such IFN inducer and having IFN-inducing activity, immunopotentiating activity, or prophylactic activity against virus infection. The agent for inducing IFN production comprises, as active ingredients, lactic acid bacteria that can activate plasmacytoid dendritic cells (pDCs) and promote IFN production, such as Lactococcus garvieae NBRC100934, Lactococcus lactis subsp. cremoris JCM16167, Lactococcus lactis subsp. cremoris NBRC100676, Lactococcus lactis subsp. hordniae JCM1180, Lactococcus lactis subsp. hordniae JCM11040, Lactococcus lactis subsp. lactis NBRC12007, Lactococcus lactis subsp. lactis NRIC1150, Lactococcus lactis subsp. lactis JCM5805, Lactococcus lactis subsp. lactis JCM20101, Leuconostoc lactis NBRC12455, Leuconostoc lactis NRIC1540, Pediococcus damnosus JCM5886, or Streptococcus thermophilus TA-45.

4. 发明授权

US09549956B2 Agent for inducing interferon production containing lactic acid bacteria 有权
标题翻译：用于诱导含有乳酸菌的干扰素生产的试剂
公开(公告)号：US09549956B2
公开(公告)日：2017-01-24
申请号：US14263306
申请日：2014-04-28
申请人： KIRIN HOLDINGS KABUSHIKI KAISHA
发明人： Daisuke Fujiwara , Kenta Jonai , Tetsu Sugimura
IPC分类号： A61K35/74 , A61K35/744 , A23C9/123 , A61K35/747 , C12N1/20 , A23C19/06 , A61K31/711 , C12N15/74 , C12Q1/68 , G01N33/68 , A23C19/032
CPC分类号： A61K35/744 , A23C9/123 , A23C9/1236 , A23C19/0323 , A23C19/062 , A23L33/135 , A23Y2240/41 , A61K9/0053 , A61K31/711 , A61K35/747 , C12N1/20 , C12N15/746 , C12Q1/6809 , C12R1/01 , G01N33/6866
摘要： This invention provides an IFN inducer comprising, as an active ingredient, lactic acid bacteria and capable of inducing IFN production, an immunopotentiating agent or prophylactic agent against virus infection comprising such inducer, and a food or drink product comprising such IFN inducer and having IFN-inducing activity, immunopotentiating activity, or prophylactic activity against virus infection. The agent for inducing IFN production comprises, as active ingredients, lactic acid bacteria that can activate plasmacytoid dendritic cells (pDCs) and promote IFN production, such as Lactococcus garvieae NBRC100934, Lactococcus lactis subsp. cremoris JCM16167, Lactococcus lactis subsp. cremoris NBRC100676, Lactococcus lactis subsp. hordniae JCM1180, Lactococcus lactis subsp. hordniae JCM11040, Lactococcus lactis subsp. lactis NBRC12007, Lactococcus lactis subsp. lactis NRIC1150, Lactococcus lactis subsp. lactis JCM5805, Lactococcus lactis subsp. lactis JCM20101, Leuconostoc lactis NBRC12455, Leuconostoc lactis NRIC1540, Pediococcus damnosus JCM5886, or Streptococcus thermophilus TA-45.
摘要翻译：本发明提供一种IFN诱导剂，其包含作为活性成分的乳酸菌并能够诱导IFN产生，包含该诱导剂的免疫增强剂或抗病毒感染的预防剂，以及包含该IFN诱导剂的食品或饮品，诱导活性，免疫增强活性或针对病毒感染的预防活性。用于诱导IFN产生的药物包括作为活性成分的可激活浆细胞样树突状细胞（pDC）并促进IFN产生的乳酸菌，例如乳球乳杆菌NBRC100934，乳酸乳球菌亚种。 cremoris JCM16167，乳酸乳球菌亚种 cremoris NBRC100676，乳酸乳球菌亚种大麦草JCM1180，乳酸乳球菌亚种大麦草JCM11040，乳酸乳球菌亚种乳酸菌NBRC12007，乳酸乳球菌亚种乳酸菌NRIC1150，乳酸乳球菌亚种乳酸菌JCM5805，乳酸乳球菌亚种乳酸菌JCM20101，乳酸列表克鲁维酵母NBRC12455，乳酸列表氨酸亮氨酸NRIC1540，侏儒球菌JCM5886或嗜热链球菌TA-45。

5. 发明授权

US11944657B2 Agent for inducing interferon production containing lactic acid bacteria 有权
公开(公告)号：US11944657B2
公开(公告)日：2024-04-02
申请号：US17548904
申请日：2021-12-13
申请人： KIRIN HOLDINGS KABUSHIKI KAISHA
发明人： Daisuke Fujiwara , Kenta Jonai , Tetsu Sugimura
IPC分类号： A61K35/744 , A23C9/123 , A23C19/032 , A23C19/06 , A23L33/135 , A61K9/00 , A61K31/711 , A61K35/747 , C12N1/20 , C12N15/74 , C12Q1/6809 , C12R1/01 , G01N33/68
CPC分类号： A61K35/744 , A23C9/123 , A23C9/1236 , A23C19/0323 , A23C19/062 , A23L33/135 , A61K9/0053 , A61K31/711 , A61K35/747 , C12N1/20 , C12N1/205 , C12N15/746 , C12Q1/6809 , G01N33/6866 , A23V2400/231 , C12R2001/01
摘要： This invention provides an IFN inducer comprising, as an active ingredient, lactic acid bacteria and capable of inducing IFN production, an immunopotentiating agent or prophylactic agent against virus infection comprising such inducer, and a food or drink product comprising such IFN inducer and having IFN-inducing activity, immunopotentiating activity, or prophylactic activity against virus infection. The agent for inducing IFN production comprises, as active ingredients, lactic acid bacteria that can activate plasmacytoid dendritic cells (pDCs) and promote IFN production, such as Lactococcus garvieae NBRC100934, Lactococcus lactis subsp. cremoris JCM16167, Lactococcus lactis subsp. cremoris NBRC100676, Lactococcus lactis subsp. hordniae JCM1180, Lactococcus lactis subsp. hordniae JCM11040, Lactococcus lactis subsp. lactis NBRC12007, Lactococcus lactis subsp. lactis NRIC1150, Lactococcus lactis subsp. lactis JCM5805, Lactococcus lactis subsp. lactis JCM20101, Leuconostoc lactis NBRC12455, Leuconostoc lactis NRIC1540, Pediococcus damnosus JCM5886, or Streptococcus thermophilus TA-45.

6. 发明授权

US11890309B2 Composition for suppressing or improving eye fatigue 有权
公开(公告)号：US11890309B2
公开(公告)日：2024-02-06
申请号：US17838698
申请日：2022-06-13
申请人： Kirin Holdings Kabushiki Kaisha
发明人： Toshihide Kurihara , Yuji Morita , Kenta Jonai , Daisuke Fujiwara
IPC分类号： A61K35/747 , A23L33/135 , A61P27/02
CPC分类号： A61K35/747 , A23L33/135 , A61P27/02
摘要： An object of the present invention is to provide a composition for preventing visual dysfunction caused by exposure to light, such as so-called blue light. The present invention provides a composition comprising a lactic acid bacterium as an active ingredient for use in suppressing or improving conditions caused by retinal inflammation resulting from light damage. Eye discomfort is an exemplary condition caused by retinal inflammation resulting from light damage.

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