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1. 发明申请

US20140105789A1 OPTICAL-WAVEGUIDE SENSOR CHIP, METHOD OF MANUFACTURING THE SAME, METHOD OF MEASURING SUBSTANCE, SUBSTANCE-MEASURING KIT AND OPTICAL-WAVEGUIDE SENSOR 有权
标题翻译：光波导传感器芯片，其制造方法，测量物质的方法，物质测量套件和光波导传感器
公开(公告)号：US20140105789A1
公开(公告)日：2014-04-17
申请号：US14141268
申请日：2013-12-26
申请人： KABUSHIKI KAISHA TOSHIBA
发明人： Shingo KASAI , Ikuo UEMATSU , Ichiro TONO , Tomohiro TAKASE , Isao NAWATA , Kayoko OOMIYA , Yuriko OYAMA , Tsutomu HONJOH
IPC分类号： G01N21/75
CPC分类号： G01N21/75 , G01N21/552 , G01N21/7703 , G01N33/54313 , G01N33/54373 , G02B6/12007 , G02B6/124
摘要： An optical-waveguide sensor chip includes an optical waveguide having a first substance immobilized on the surface thereof, the first substance being specifically reactive with an analyte substance, and fine particles dispersed on the optical waveguide and having a second substance immobilized on the surface thereof, the second substance being specifically reactive with the analyte substance.
摘要翻译：光波导传感器芯片包括具有固定在其表面上的第一物质的光波导，第一物质与分析物质特异性反应，以及分散在光波导上并且固定在其表面上的第二物质的细颗粒，第二物质与分析物质特异性反应。

2. 发明申请

US20150177125A1 MEASUREMENT SYSTEM USING OPTICAL WAVEGUIDE 审中-公开
标题翻译：使用光波导的测量系统
公开(公告)号：US20150177125A1
公开(公告)日：2015-06-25
申请号：US14569885
申请日：2014-12-15
申请人： Kabushiki Kaisha Toshiba
发明人： Shingo KASAI
IPC分类号： G01N21/17
CPC分类号： G01N21/7703 , G01N21/552 , G01N33/54333 , G01N2021/1727 , G01N2021/7783
摘要： According to one embodiment, a measurement system which includes an optical waveguide, magnetic fine particles, a first magnetic field application unit, a second magnetic field application unit and a controller is provided. A first material specifically bonding with a target substance is immobilized on a surface of the optical waveguide. A second material specifically bonding with the target substance is immobilized on a surface of the magnetic fine particle. The first magnetic field application unit generates a magnetic field that moves the magnetic fine particles in a direction away from the optical waveguide. The second magnetic field application unit generates a magnetic field that moves the magnetic fine particles in a direction of approaching the optical waveguide. The controller controls the first magnetic field application unit to apply the magnetic field intermittently in a state where the second magnetic field application unit applies the magnetic field.
摘要翻译：根据一个实施例，提供一种包括光波导，磁性细颗粒，第一磁场施加单元，第二磁场施加单元和控制器的测量系统。与目标物质特异性结合的第一种材料固定在光波导的表面上。与目标物质特异性结合的第二种材料被固定在磁性细颗粒的表面上。第一磁场施加单元产生使磁性微粒沿远离光波导的方向移动的磁场。第二磁场施加单元产生使磁性微粒沿接近光波导的方向移动的磁场。控制器控制第一磁场施加单元在第二磁场施加单元施加磁场的状态下间歇地施加磁场。

3. 发明申请

US20130309779A1 OPTICAL WAVEGUIDE MEASUREMENT SYSTEM AND METHOD FOR MEASURING GLYCATED HEMOGLOBIN 审中-公开
标题翻译：光学波形测量系统和测量糖化血红蛋白的方法
公开(公告)号：US20130309779A1
公开(公告)日：2013-11-21
申请号：US13834958
申请日：2013-03-15
申请人： KABUSHIKI KAISHA TOSHIBA
发明人： Shingo KASAI , Ichiro TONO
IPC分类号： G01N33/543
CPC分类号： G01N33/54373 , G01N33/54333 , G01N33/723
摘要： According one embodiment, an optical waveguide measurement system includes a first optical waveguide immobilizing a first substance, the first substance being able to be specifically bound to glycated hemoglobin; a plurality of first magnetic microparticles immobilizing a second substance immobilized, the second substance being able to be specifically bound to the glycated hemoglobin at a first site different from a second site, and the first substance can be specifically bound to the glycated hemoglobin at the second site; a first magnetic field applying section provided above the first optical waveguide and being able to move at least one of the plurality of first magnetic microparticles by magnetic force; a first light source being able to inject light into the first optical waveguide; and a first light receiving element being able to receive light ejected from the first optical waveguide.
摘要翻译：根据一个实施例，光波导测量系统包括固定第一物质的第一光波导，第一物质能够特异性结合糖化血红蛋白; 多个第一磁性微粒固定化固定的第二物质，所述第二物质能够在不同于第二位点的第一位置与所述糖化血红蛋白特异性结合，所述第一物质可以在第二物质上特异性地结合到糖化血红蛋白现场; 第一磁场施加部，设置在所述第一光波导的上方，能够通过磁力移动所述多个第一磁性微粒中的至少一个; 能够将光注入到第一光波导中的第一光源; 以及能够接收从第一光波导排出的光的第一光接收元件。

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