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1. 发明申请

US20130202566A1 METHOD FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS TO NERVE CELLS USING SOUND WAVES 有权
标题翻译：使用声波诱导神经干细胞分化为神经细胞的方法
公开(公告)号：US20130202566A1
公开(公告)日：2013-08-08
申请号：US13702982
申请日：2011-06-08
申请人： Jung-Keug Park , Moon Young Yoon , Hyun Jin Cho , Young-Kwon Seo , Song Hee Jeon , Hee Hoon Yoon
发明人： Jung-Keug Park , Moon Young Yoon , Hyun Jin Cho , Young-Kwon Seo , Song Hee Jeon , Hee Hoon Yoon
IPC分类号： C12N13/00
CPC分类号： C12N5/0619 , C12N5/0618 , C12N13/00 , C12N2506/1346 , C12N2506/1353 , C12N2506/1361 , C12N2506/1369 , C12N2506/1384 , C12N2529/00
摘要： The present invention relates to a method for differentiation of mesenchymal stem cells. More specifically, the invention relates to a method for differentiating mesenchymal stem cells to neural cells by treating the mesenchymal stem cells with low-frequency sound waves. The differentiation method of the present invention can induce differentiation even with low-cost media rather than induced neural differentiation mediums which are expensive due to addition of growth factors, and the neural cells differentiated according to the present invention may be useful for treatment of neurological diseases.
摘要翻译：本发明涉及分化间充质干细胞的方法。更具体地，本发明涉及通过用低频声波处理间充质干细胞来将间充质干细胞分化为神经细胞的方法。本发明的分化方法即使使用低成本培养基也可诱导分化，而不是由于生长因子的添加而引起的神经分化培养基昂贵，根据本发明分化的神经细胞可用于治疗神经系统疾病。

2. 发明授权

US08753881B2 Method for inducing differentiation of mesenchymal stem cells to nerve cells using sound waves 有权
标题翻译：使用声波诱导间充质干细胞分化为神经细胞的方法
公开(公告)号：US08753881B2
公开(公告)日：2014-06-17
申请号：US13702982
申请日：2011-06-08
申请人： Jung-Keug Park , Moon Young Yoon , Hyun Jin Cho , Young-Kwon Seo , Song Hee Jeon , Hee Hoon Yoon
发明人： Jung-Keug Park , Moon Young Yoon , Hyun Jin Cho , Young-Kwon Seo , Song Hee Jeon , Hee Hoon Yoon
IPC分类号： C12N5/00 , C12N5/079 , C12N5/077
CPC分类号： C12N5/0619 , C12N5/0618 , C12N13/00 , C12N2506/1346 , C12N2506/1353 , C12N2506/1361 , C12N2506/1369 , C12N2506/1384 , C12N2529/00
摘要： The present invention relates to a method for differentiation of mesenchymal stem cells. More specifically, the invention relates to a method for differentiating mesenchymal stem cells to neural cells by treating the mesenchymal stem cells with low-frequency sound waves. The differentiation method of the present invention can induce differentiation even with low-cost media rather than induced neural differentiation mediums which are expensive due to addition of growth factors, and the neural cells differentiated according to the present invention may be useful for treatment of neurological diseases.
摘要翻译：本发明涉及分化间充质干细胞的方法。更具体地，本发明涉及通过用低频声波处理间充质干细胞来将间充质干细胞分化为神经细胞的方法。本发明的分化方法即使使用低成本培养基也可诱导分化，而不是由于生长因子的添加而引起的神经分化培养基昂贵，根据本发明分化的神经细胞可用于治疗神经系统疾病。

3. 发明授权

US08673605B2 Method for inducing differentiation of adult stem cells and nerve cells using electromagnetic field 有权
标题翻译：使用电磁场诱导成体干细胞和神经细胞分化的方法
公开(公告)号：US08673605B2
公开(公告)日：2014-03-18
申请号：US13702975
申请日：2011-06-08
申请人： Jung-Keug Park , Sung Min Kim , Soo Chan Kim , Moon Young Yoon , Hyun Jin Cho , Young-Kwon Seo , Hee Hoon Yoon
发明人： Jung-Keug Park , Sung Min Kim , Soo Chan Kim , Moon Young Yoon , Hyun Jin Cho , Young-Kwon Seo , Hee Hoon Yoon
IPC分类号： A01N63/00 , C12N13/00 , C12N5/0793
CPC分类号： C12N5/0619 , C12N5/0618 , C12N13/00 , C12N2506/1346 , C12N2506/1353 , C12N2506/1361 , C12N2506/1369 , C12N2506/1384 , C12N2529/00
摘要： The present invention relates to a method for differentiation of mesenchymal stem cells or dental pulp stem cells. More specifically, the invention relates to a method for differentiating stem cells to neural cells by applying mesenchymal stem cells or dental pulp stem cells with a low-frequency electromagnetic field. The differentiation method according to the present invention can induce differentiation even with low-cost mediums rather than induced neural differentiation mediums which are expensive due to addition of growth factors, and the neural cells differentiated according to the present invention may be useful for treatment of neurological brain diseases.
摘要翻译：本发明涉及分化间充质干细胞或牙髓干细胞的方法。更具体地，本发明涉及通过用低频电磁场施用间充质干细胞或牙髓干细胞来分化干细胞与神经细胞的方法。根据本发明的分化方法即使使用低成本培养基也可诱导分化，而不是由于生长因子的添加而昂贵的诱导神经分化培养基，并且根据本发明分化的神经细胞可用于治疗神经系统脑疾病

4. 发明申请

US20130202565A1 METHOD FOR INDUCING DIFFERENTIATION OF ADULT STEM CELLS AND NERVE CELLS USING ELECTROMAGNETIC FIELD 有权
标题翻译：使用电磁场诱导成年干细胞和神经细胞分化的方法
公开(公告)号：US20130202565A1
公开(公告)日：2013-08-08
申请号：US13702975
申请日：2011-06-08
申请人： Jung-Keug Park , Sung Min Kim , Soo Chan Kim , Moon Young Yoon , Hyun Jin Cho , Young-Kwon Seo , Hee Hoon Yoon
发明人： Jung-Keug Park , Sung Min Kim , Soo Chan Kim , Moon Young Yoon , Hyun Jin Cho , Young-Kwon Seo , Hee Hoon Yoon
IPC分类号： C12N13/00
CPC分类号： C12N5/0619 , C12N5/0618 , C12N13/00 , C12N2506/1346 , C12N2506/1353 , C12N2506/1361 , C12N2506/1369 , C12N2506/1384 , C12N2529/00
摘要： The present invention relates to a method for differentiation of mesenchymal stem cells or dental pulp stem cells. More specifically, the invention relates to a method for differentiating stem cells to neural cells by applying mesenchymal stem cells or dental pulp stem cells with a low-frequency electromagnetic field. The differentiation method according to the present invention can induce differentiation even with low-cost mediums rather than induced neural differentiation mediums which are expensive due to addition of growth factors, and the neural cells differentiated according to the present invention may be useful for treatment of neurological brain diseases.
摘要翻译：本发明涉及分化间充质干细胞或牙髓干细胞的方法。更具体地，本发明涉及通过用低频电磁场施用间充质干细胞或牙髓干细胞来分化干细胞与神经细胞的方法。根据本发明的分化方法即使使用低成本培养基也可诱导分化，而不是由于生长因子的添加而昂贵的诱导神经分化培养基，并且根据本发明分化的神经细胞可用于治疗神经系统脑疾病

5. 发明授权

US09034394B2 Methods of preparing red clay processed material and alkali ionized water 有权
标题翻译：制备红土加工材料和碱电离水的方法
公开(公告)号：US09034394B2
公开(公告)日：2015-05-19
申请号：US13576870
申请日：2010-02-03
申请人： Jung-Keug Park , Moon Young Yoon
发明人： Jung-Keug Park , Moon Young Yoon
IPC分类号： C02F1/50 , C04B33/14 , C04B33/32 , C04B35/626
CPC分类号： C02F1/50 , C02F2303/08 , C04B33/14 , C04B33/323 , C04B35/6261 , C04B2235/3201 , C04B2235/3206 , C04B2235/3208 , C04B2235/3232 , C04B2235/3272 , C04B2235/447 , C04B2235/656 , C04B2235/6567
摘要： Provided is a method of preparing a red clay processed material using red clay and sodium hydroxide and a red clay processed material having anti-corrosive and virus disinfecting activity. Also, a method of preparing alkali ionized water having excellent anti-bacterial, virus disinfecting and anti-corrosive activity using the red clay processed material, alkali ionized water using the same, and a functional product including the same are provided. The red clay processed material and the method of preparing alkali ionized water using the same can reduce the reaction temperature and reaction time compared to a conventional process, thereby significantly reducing the production cost. The red clay processed material and the alkali ionized water have excellent anti-bacterial, anti-corrosive, and virus disinfecting activity and are not toxic, so they can be widely applied in various health-care and agricultural, livestock, and marine fields such as an agent for preventing viral infectious diseases, a food preservative, a natural agricultural pesticide or fertilizer, paint, feed, an eco-friendly construction material, a red tide/green tide inhibitor, a cosmetic additive, or an anti-corrosive agent.
摘要翻译：提供了使用红粘土和氢氧化钠制备红土加工材料的方法和具有防腐和病毒消毒活性的红土加工材料。此外，提供了使用红粘土处理材料制备具有优异的抗细菌，病毒消毒和抗腐蚀活性的碱性离子水的方法，使用该离子水的碱性电离水以及包含它们的功能性产物。红粘土处理材料和使用其的碱性电离水的制备方法可以降低与常规方法相比的反应温度和反应时间，从而显着降低生产成本。红土加工材料和碱性电离水具有优良的抗菌，抗腐蚀和病毒消毒活性，无毒，可广泛应用于各种保健，农业，畜牧，海洋等领域防止病毒性传染病的药剂，食品防腐剂，天然农药或肥料，油漆，饲料，环保建筑材料，红潮/绿潮抑制剂，化妆品添加剂或防腐剂。

6. 发明申请

US20120321725A1 METHODS OF PREPARING RED CLAY PROCESSED MATERIAL AND ALKALI IONIZED WATER 有权
标题翻译：制备红色粘土材料和碱性离子水的方法
公开(公告)号：US20120321725A1
公开(公告)日：2012-12-20
申请号：US13576870
申请日：2010-02-03
申请人： Jung-Keug Park , Moon Young Yoon
发明人： Jung-Keug Park , Moon Young Yoon
IPC分类号： A01N59/00 , A01P1/00 , C09K15/02
CPC分类号： C02F1/50 , C02F2303/08 , C04B33/14 , C04B33/323 , C04B35/6261 , C04B2235/3201 , C04B2235/3206 , C04B2235/3208 , C04B2235/3232 , C04B2235/3272 , C04B2235/447 , C04B2235/656 , C04B2235/6567
摘要： Provided is a method of preparing a red clay processed material using red clay and sodium hydroxide and a red clay processed material having anti-corrosive and virus disinfecting activity. Also, a method of preparing alkali ionized water having excellent anti-bacterial, virus disinfecting and anti-corrosive activity using the red clay processed material, alkali ionized water using the same, and a functional product including the same are provided. The red clay processed material and the method of preparing alkali ionized water using the same can reduce the reaction temperature and reaction time compared to a conventional process, thereby significantly reducing the production cost. The red clay processed material and the alkali ionized water have excellent anti-bacterial, anti-corrosive, and virus disinfecting activity and are not toxic, so they can be widely applied in various health-care and agricultural, livestock, and marine fields such as an agent for preventing viral infectious diseases, a food preservative, a natural agricultural pesticide or fertilizer, paint, feed, an eco-friendly construction material, a red tide/green tide inhibitor, a cosmetic additive, or an anti-corrosive agent.
摘要翻译：提供了使用红粘土和氢氧化钠制备红土加工材料的方法和具有防腐和病毒消毒活性的红土加工材料。此外，提供了使用红粘土处理材料制备具有优异的抗细菌，病毒消毒和抗腐蚀活性的碱性离子水的方法，使用该离子水的碱性电离水以及包含它们的功能性产物。红粘土处理材料和使用其的碱性电离水的制备方法可以降低与常规方法相比的反应温度和反应时间，从而显着降低生产成本。红土加工材料和碱性电离水具有优良的抗菌，抗腐蚀和病毒消毒活性，无毒，可广泛应用于各种保健，农业，畜牧，海洋等领域防止病毒性传染病的药剂，食品防腐剂，天然农药或肥料，油漆，饲料，环保建筑材料，红潮/绿潮抑制剂，化妆品添加剂或防腐剂。

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