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1. 发明授权

US08410277B2 Method for manufacturing heterocycle substituted pyridine derivatives 失效
标题翻译：制备杂环取代吡啶衍生物的方法
公开(公告)号：US08410277B2
公开(公告)日：2013-04-02
申请号：US12809011
申请日：2008-12-25
申请人： Jun Niijima , Kazuhiro Yoshizawa , Yuki Kosaka , Shinya Abe
发明人： Jun Niijima , Kazuhiro Yoshizawa , Yuki Kosaka , Shinya Abe
IPC分类号： C07D413/14
CPC分类号： C07D498/04 , C07D213/46 , C07D213/643 , C07D413/04 , C07D413/14 , Y02P20/55
摘要： It is an object of the present invention to provide an efficient method for manufacturing heterocycle-substituted pyridine derivatives. The present invention provides a method for manufacturing a compound represented by the following formula (I): the method including reacting a compound represented by the following formula (III): and a compound represented by the following formula (II): in a solvent and in the presence of a palladium catalyst and a base, wherein R1 represents a hydrogen atom, etc.; R2 represents a hydrogen atom, a C1-6 alkyl group, an amino group that may be protected with a protective group, etc.; one of X and Y represents a nitrogen atom and the other represents a nitrogen atom or an oxygen atom; Q represents a leaving group; the ring A represents a 5- or 6-member heteroaryl ring or a benzene ring, which may have one or two halogen atoms or C1-6 alkyl groups; Z represents a single bond, a methylene group, an ethylene group, an oxygen atom, etc.; R represents a hydrogen atom or a C1-6 alkyl group, etc.; R3 represents a hydrogen atom or a halogen atom, etc.; and R4 represents a hydrogen atom or a halogen atom; provided that when Z represents a single bond, or when R3 represents a hydrogen atom, then R1, R2, and R4 cannot all be a hydrogen atom at the same time.
摘要翻译：本发明的目的是提供一种制备杂环取代的吡啶衍生物的有效方法。本发明提供下述式（I）表示的化合物的制造方法：使下述式（III）表示的化合物与下述式（II）所示的化合物反应的方法：在溶剂和在钯催化剂和碱的存在下，其中R1表示氢原子等; R2表示氢原子，C1-6烷基，可被保护基保护的氨基等; X和Y中的一个表示氮原子，另一个表示氮原子或氧原子; Q表示离去组; 环A表示可具有一个或两个卤素原子或C 1-6烷基的5-或6-元杂芳环或苯环; Z表示单键，亚甲基，亚乙基，氧原子等; R表示氢原子或C 1-6烷基等; R3表示氢原子或卤素原子等; R4代表氢原子或卤原子; 条件是当Z表示单键时，或当R3表示氢原子时，则R1，R2和R4不能同时为氢原子。

2. 发明申请

US20110263845A1 METHOD FOR MANUFACTURING HETEROCYCLE SUBSTITUTED PYRIDINE DERIVATIVES 失效
标题翻译：制备杂环取代的吡啶衍生物的方法
公开(公告)号：US20110263845A1
公开(公告)日：2011-10-27
申请号：US12809011
申请日：2008-12-25
申请人： Jun Niijima , Kazuhiro Yoshizawa , Yuki Kosaka , Shinya Abe
发明人： Jun Niijima , Kazuhiro Yoshizawa , Yuki Kosaka , Shinya Abe
IPC分类号： C07D498/04 , C07D413/04 , C07F5/02 , C07D213/64 , C07D413/14 , C07F5/04
CPC分类号： C07D498/04 , C07D213/46 , C07D213/643 , C07D413/04 , C07D413/14 , Y02P20/55
摘要： It is an object of the present invention to provide an efficient method for manufacturing heterocycle-substituted pyridine derivatives. The present invention provides a method for manufacturing a compound represented by the following formula (I): the method including reacting a compound represented by the following formula (III): and a compound represented by the following formula (II): in a solvent and in the presence of a palladium catalyst and a base, wherein R1 represents a hydrogen atom, etc.; R2 represents a hydrogen atom, a C1-6 alkyl group, an amino group that may be protected with a protective group, etc.; one of X and Y represents a nitrogen atom and the other represents a nitrogen atom or an oxygen atom; Q represents a leaving group; the ring A represents a 5- or 6-member heteroaryl ring or a benzene ring, which may have one or two halogen atoms or C1-6 alkyl groups; Z represents a single bond, a methylene group, an ethylene group, an oxygen atom, etc.; R represents a hydrogen atom or a C1-6 alkyl group, etc.; R3 represents a hydrogen atom or a halogen atom, etc.; and R4 represents a hydrogen atom or a halogen atom; provided that when Z represents a single bond, or when R3 represents a hydrogen atom, then R1, R2, and R4 cannot all be a hydrogen atom at the same time.
摘要翻译：本发明的目的是提供一种制备杂环取代的吡啶衍生物的有效方法。本发明提供下述式（I）表示的化合物的制造方法：使下述式（III）表示的化合物与下述式（II）所示的化合物反应的方法：在溶剂和在钯催化剂和碱的存在下，其中R1表示氢原子等; R2表示氢原子，C1-6烷基，可被保护基保护的氨基等; X和Y中的一个表示氮原子，另一个表示氮原子或氧原子; Q表示离去组; 环A表示可具有一个或两个卤素原子或C 1-6烷基的5-或6-元杂芳环或苯环; Z表示单键，亚甲基，亚乙基，氧原子等; R表示氢原子或C 1-6烷基等; R3表示氢原子或卤素原子等; R4代表氢原子或卤原子; 条件是当Z表示单键时，或当R3表示氢原子时，则R1，R2和R4不能同时为氢原子。

3. 发明申请

US20100094001A1 COMPOSITION CONTAINING STABILITY-IMPROVED CHLOROMETHYL PHOSPHATE DERIVATIVE AND PROCESS FOR PRODUCING SAME 审中-公开
标题翻译：包含稳定性改进的氯代氯代磷酸酯衍生物的组合物及其生产方法
公开(公告)号：US20100094001A1
公开(公告)日：2010-04-15
申请号：US12526905
申请日：2008-03-05
申请人： Keizo Sato , Shinya Abe , Kazuhiro Yoshizawa , Kazunori Wakasugi , Shigeto Negi , Mamoru Miyazawa
发明人： Keizo Sato , Shinya Abe , Kazuhiro Yoshizawa , Kazunori Wakasugi , Shigeto Negi , Mamoru Miyazawa
IPC分类号： C07D265/30 , C07F9/06
CPC分类号： C07F9/025 , C07F9/091
摘要： The present invention provides a process or the like which is employed for producing chloromethyl phosphate derivatives that are useful for producing water-soluble prodrugs, and which are excellent from the points of view of workability, operativity and energy saving. According to the present invention, there is provided a process for producing a composition containing a compound represented by the following formula (I) and a tertiary amine, (wherein R1 and R2 are identical or different from each other, and represent a C1-C6 alkyl group, a C2-C6 alkenyl group or a C6-C14 aryl C1-C6 alkyl group which may have a substituent, and R1 and R2 may together form a ring), the process comprising the step of adding the tertiary amine having a boiling point at 1 atmosphere of 150° C. or higher to the compound represented by formula (I).
摘要翻译：本发明提供了用于制备可用于制备水溶性前药的氯甲基磷酸酯衍生物的方法等，从可加工性，操作性和节能性的观点出发，优选。根据本发明，提供一种制备含有下式（I）表示的化合物和叔胺的组合物的方法，其中R1和R2彼此相同或不同，并表示C1-C6 烷基，C 2 -C 6烯基或可以具有取代基的C 6 -C 14芳基C 1 -C 6烷基，R 1和R 2可以一起形成环），该方法包括将具有沸点在由式（I）表示的化合物的150℃以上的1个大气压下进行。

4. 发明授权

US08953090B2 Camera device, interchangeable lens device, camera main body, and focus control method 有权
标题翻译：相机装置，可互换镜头装置，相机主体和聚焦控制方法
公开(公告)号：US08953090B2
公开(公告)日：2015-02-10
申请号：US14129861
申请日：2012-02-28
申请人： Takeru Hokkezu , Shinya Abe
发明人： Takeru Hokkezu , Shinya Abe
IPC分类号： H04N5/232 , H04N5/76 , H04N5/217 , H04N5/225 , G02B7/36 , G03B3/10 , G03B17/14
CPC分类号： H04N5/2254 , G02B7/36 , G03B3/10 , G03B17/14 , G03B2205/0007 , H04N5/232 , H04N5/23209 , H04N5/23212
摘要： A lens controller of a camera device includes: a driving amount calculator that samples, for each first time period, a lens position signal indicating a lens position detected by a lens position detector and a target position signal indicating a target position of a focus lens on an optical axis transmitted from a control unit and calculates a driving amount output of the focus lens based on the sampled lens position signal and target position signal; an up-sampling unit that performs up-sampling on the driving amount output obtained by the driving amount calculator at a second time period which is a period obtained by dividing the first time period by an integer; and a resonance suppression calculator that performs calculation on a result obtained by sampling the driving amount output at the second time period to suppress a higher-order resonant frequency component in a specified resonant frequency band.
摘要翻译：相机装置的镜头控制器包括：驱动量计算器，对于每个第一时间段，对表示由镜头位置检测器检测到的镜头位置的镜头位置信号和指示聚焦透镜的目标位置的目标位置信号进行采样从控制单元发送的光轴，并基于所取得的透镜位置信号和目标位置信号，计算出聚焦透镜的驱动量输出; 上采样单元，在通过将第一时间段除以整数而获得的周期的第二时间段，对由驱动量计算器获得的驱动量输出进行上采样; 以及共振抑制计算器，其对通过对在第二时间段输出的驱动量进行采样而获得的结果进行计算，以抑制特定谐振频带中的高次谐振频率分量。

5. 发明授权

US07845367B2 Lock device for operation pattern selecting valve 有权
标题翻译：操作模式选择阀锁定装置
公开(公告)号：US07845367B2
公开(公告)日：2010-12-07
申请号：US11828914
申请日：2007-07-26
申请人： Shinya Abe
发明人： Shinya Abe
IPC分类号： F16K35/06
CPC分类号： F16K35/06 , Y10T70/5615 , Y10T70/5624 , Y10T70/5637 , Y10T137/7069 , Y10T137/7256
摘要： A lock device includes a first bracket 34 fixed to a screw element 33 and formed with a lock hole 34b; a second bracket 35 which has a fitting portion 35a fitted to the turn-type control lever 30 of an operation pattern selecting valve 16 and which is formed with a lock hole 35f; and a lock 36. The screw element 33 is screwed into a threaded hole 32 formed in an end plate 29 of the operation pattern selecting valve 16 to secure the first bracket 34 to the end plate 29. The fitting portion 35a of the second bracket 35 is fitted to the turn-type control lever 30 to connect the second bracket 35 to the turn-type control lever 30. The lock 36 is insertably attached to the respective lock holes 34b and 35f of the first bracket 34 and second bracket 35 for locking the turn-type control lever 30. With such a structure, the lock device can be manufactured relatively easily without the necessity of processing the operation pattern selecting valve.
摘要翻译：锁定装置包括：第一支架34，其固定在螺钉元件33上并形成有锁定孔34b; 第二支架35，其具有嵌合在操作模式选择阀16的转动型控制杆30上并且形成有锁定孔35f的嵌合部35a; 螺钉元件33旋入形成在操作模式选择阀16的端板29上的螺纹孔32中，以将第一托架34固定在端板29上。第二托架35的嵌合部分35a 安装在转向型控制杆30上，以将第二支架35连接到转向控制杆30.锁36可插入地附接到第一支架34的相应的锁定孔34b和35f以及用于锁定的第二支架35 通过这种结构，可以相对容易地制造锁定装置，而无需处理操作模式选择阀。

6. 发明授权

US07782746B2 Optical information recording medium and method for manufacturing same 失效
标题翻译：光学信息记录介质及其制造方法
公开(公告)号：US07782746B2
公开(公告)日：2010-08-24
申请号：US11956127
申请日：2007-12-13
申请人： Keiji Nishikiori , Eiji Ohno , Shinya Abe
发明人： Keiji Nishikiori , Eiji Ohno , Shinya Abe
IPC分类号： G11B7/24
CPC分类号： G11B7/24067 , G11B7/24053
摘要： An optical information recording medium that has a simple structure and with which warpage is kept to a minimum even under environmental changes over a wide range, and a method for manufacturing this medium are provided. The optical information recording medium is an optical information recording medium used for the reproduction of recorded information and for recording and reproduction, including a substrate having an information recording layer, and a light transmitting layer that covers the information recording layer and is composed of a radiation curable resin, wherein a warpage adjusting layer for adjusting warpage of the light transmitting layer caused by temperature changes is disposed on the opposite side of the substrate from the side on which the information recording layer is formed. There is included at least a temperature region that satisfies the relationship that the coefficient of linear expansion CL of the light transmitting layer
摘要翻译：提供具有简单结构并且即使在宽范围内的环境变化下翘曲也保持最小的光学信息记录介质，以及制造该介质的方法。光信息记录介质是用于再现记录信息并用于记录和再现的光学信息记录介质，包括具有信息记录层的基板和覆盖信息记录层并由辐射组成的光透射层固化树脂，其中用于调节由温度变化引起的透光层的翘曲的翘曲调节层设置在从形成信息记录层的一侧的基板的相对侧。至少包含满足在室温下的透光层的线膨胀系数CL（翘曲调节层的线膨胀系数SL）的系数的关系的温度区域。

7. 发明申请

US20100168173A1 HETEROCYCLES SUBSTITUTED PYRIDINE DERIVATIVES AND ANTIFUNGAL AGENT CONTAINING THEREOF 有权
公开(公告)号：US20100168173A1
公开(公告)日：2010-07-01
申请号：US12704637
申请日：2010-02-12
申请人： Keigo Tanaka , Satoshi Inoue , Norio Murai , Masayuki Matsukura , Kazutaka Nakamoto , Shuji Shirotori , Shinya Abe
发明人： Keigo Tanaka , Satoshi Inoue , Norio Murai , Masayuki Matsukura , Kazutaka Nakamoto , Shuji Shirotori , Shinya Abe
IPC分类号： A61K31/444 , C07D413/04 , A61K31/4439 , C07D401/14 , A61P31/10
CPC分类号： A01N43/56 , A01N43/80 , C07D401/04 , C07D401/14 , C07D413/04 , C07D413/14 , C07D417/14
摘要： An object of the present invention is to provide an antifungal agent which has excellent antifungal effects and is superior in terms of its physical properties, safety and metabolic stability. According to the present invention, there is disclosed a compound represented by the following formula (I), or a salt thereof: wherein R1 represents a hydrogen atom, a halogen atom, an amino group, a C1-6 alkyl group, a C1-6 alkoxy group or a C1-6 alkoxy C1-6 alkyl group; R2 represents a hydrogen atom, a C1-6 alkyl group, an amino group or a di C1-6 alkylamino group; one of X and Y is a nitrogen atom while the other is a nitrogen atom or an oxygen atom; ring A represents a 5- or 6-member heteroaryl ring or a benzene ring which may have a halogen atom, or 1 or 2 C1-6 alkyl groups; Z represents a single bond, a methylene group, an ethylene group, an oxygen atom, a sulfur atom, —CH2O—, —OCH2—, —NH—, —CH2NH—, —NHCH2—, —CH2S—, or —SCH2—; R3 represents a hydrogen atom, a halogen atom, a C1-6 alkyl group, a C3-8 cycloalkyl group, a C6-10 aryl group, a 5- or 6-member heteroaryl group, or 5- or 6-member non-aromatic heterocyclic group which may have 1 or 2 substituents; and R4 represents a hydrogen atom or a halogen atom.

8. 发明授权

US07616552B2 Phase-change optical recording medium having first and second track pitches 有权
标题翻译：具有第一和第二轨道间距的相变光学记录介质
公开(公告)号：US07616552B2
公开(公告)日：2009-11-10
申请号：US10504292
申请日：2003-02-10
申请人： Shinya Abe , Shin-ichi Tanaka , Hiroshi Ogawa , Jacobus Petrus Josephus Heemskerk , Tamotsu Yamagami , Cornelis Marinus Schep
发明人： Shinya Abe , Shin-ichi Tanaka , Hiroshi Ogawa , Jacobus Petrus Josephus Heemskerk , Tamotsu Yamagami , Cornelis Marinus Schep
IPC分类号： G11B7/24
CPC分类号： G11B23/284 , G11B7/0053 , G11B7/00736 , G11B7/24079 , G11B20/00086 , G11B20/1217 , G11B20/1403 , G11B23/0042 , G11B23/30 , G11B2020/122 , G11B2020/1238 , G11B2020/1277 , G11B2220/2537
摘要： An optical disc or other optical recording medium enables reading barcode-shaped-BCA marks in a burst cutting area (BCA) with tracking on while making tampering with the BCA marks difficult. The optical disc 100 has a first area 102 containing tracks at a first track pitch d2, and a second area 101 containing tracks at a second track pitch d1. The barcode-shaped marks 104 are recorded in the second area, and the second track pitch is wider than the first track pitch.
摘要翻译：光盘或其它光学记录介质能够在具有追踪功能的突发切割区域（BCA）中读取条形码形BCA标记，同时难以篡改BCA标记。光盘100具有包含第一轨道间距d2的轨道的第一区域102和包含第二轨道间距d1的轨道的第二区域101。条形码标记104被记录在第二区域中，并且第二轨道间距比第一轨道间距宽。

9. 发明授权

US07539121B2 Optical recording medium and process for producing the same 有权
标题翻译：光记录介质及其制造方法
公开(公告)号：US07539121B2
公开(公告)日：2009-05-26
申请号：US10550069
申请日：2004-04-01
申请人： Morio Tomiyama , Shinya Abe , Yuuko Kawaguchi , Eiji Ohno
发明人： Morio Tomiyama , Shinya Abe , Yuuko Kawaguchi , Eiji Ohno
IPC分类号： G11B7/24
CPC分类号： G11B7/24079 , G11B7/24038 , G11B7/24085
摘要： An optical recording medium is provided with: a first substrate having first pits on one face thereof; a first reflective layer that is formed on the face bearing the first pits of the first substrate in a manner so as to reflect lands and recesses of the first pits; a second substrate that is formed on the first reflective layer, with second pits being formed on a face on the side opposite to the first reflective layer; a second reflective layer that is formed on the face bearing the second pits of the second substrate in a manner so as to reflect lands and recesses of the second pits; and a cover layer formed on the second reflective layer. In this structure, the first pit depth d1 that is a difference between lands and recesses of the first reflective layer, the wavelength λ of signal-reproducing laser light and the refractive index n1 of the second substrate satisfy the following relational expressions: λ/(5n1)≦d1≦λ/(3n1) and d1≠λ/(4n1). Moreover, the second pit depth d2, which is a difference between lands and recesses of the second reflective layer, the wavelength λ of signal-reproducing laser light and the refractive index n2 of the cover layer satisfy the following relational expressions: λ/(5n2)≦d2≦λ/(3n2) and d2≠λ/(4n2).
摘要翻译：光记录介质设置有：第一基板，其一面上具有第一凹坑; 第一反射层，其形成在承载第一基板的第一凹坑的表面上，以便反映第一凹坑的凹槽和凹陷; 形成在第一反射层上的第二基板，第二凹坑形成在与第一反射层相对的一侧的表面上; 第二反射层，其形成在承载第二基板的第二凹坑的表面上，以便反射第二凹坑的凹陷和凹陷; 以及形成在所述第二反射层上的覆盖层。在该结构中，作为第一反射层的区域和凹部之间的差的第一凹坑深度d1，信号再现激光的波长λ和第二基板的折射率n1满足以下关系式：λ/（ 5n1）<= d1 <= lambda /（3n1）和d1 <> lambda /（4n1）。此外，作为第二反射层的区域和凹部之间的差异的第二凹坑深度d2，信号再现激光的波长λ和覆盖层的折射率n2满足以下关系式：λ/（5n2 ）<= d2 <= lambda /（3n2）和d2 <λλ/（4n2）。

10. 发明授权

US07236434B2 Exposure apparatus of an optical disk master, method of exposing an optical disk master, and wavefront fluctuation correction mechanism 失效
标题翻译：光盘主机的曝光装置，曝光光盘主机的方法以及波前波动校正机构
公开(公告)号：US07236434B2
公开(公告)日：2007-06-26
申请号：US10975605
申请日：2004-10-28
申请人： Masahiko Tsukuda , Shinya Abe , Morio Tomiyama , Shuji Sato , Eiichi Ito
发明人： Masahiko Tsukuda , Shinya Abe , Morio Tomiyama , Shuji Sato , Eiichi Ito
IPC分类号： G11B7/26 , G11B7/135
CPC分类号： G11B7/261 , G11B7/128 , G11B7/1378
摘要： Apparatus and method for exposing an optical disk master having a laser source, a deflector for deflecting a recording laser beam based on the laser beam of the laser source and an objective lens for focusing the recording laser beam on an optical disk master, including a liquid crystal plate provided between the laser source and the deflector, a parallel flat plate provided between the deflector and the objective lens, a photodetector that detects reflected light from the parallel flat plate, and an adjusting device for adjusting a voltage applied to the liquid crystal plate based on information on wavefront fluctuation of the recording laser beam detected by the photodetector.
摘要翻译：用于曝光具有激光源的光盘主机的装置和方法，用于基于激光源的激光束偏转记录激光束的偏转器和用于将记录激光束聚焦在包括液体的光盘主机的物镜设置在激光源和偏转器之间的晶体板，设置在偏转器和物镜之间的平行平板，检测来自平行平板的反射光的光电检测器，以及用于调节施加到液晶板的电压的调节装置基于由光电检测器检测的记录激光束的波前波动的信息。

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