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1. 发明授权

US08846750B2 Pharmaceutical and food compositions for preventing or treating diabetes or obesity 有权
公开(公告)号：US08846750B2
公开(公告)日：2014-09-30
申请号：US13878196
申请日：2011-07-01
申请人： Joung Han Yim , Il Chan Kim , Doc Kyu Kim , Se Jong Han , Hyoung Seok Lee , Bhattarai Hari Datta , Jung Eun Kim , Tai Kyoung Kim , Hyun Cheol Oh , Dong-Gyu Jo , Cheolsoon Lee , Keun-Sik Kim , Pyung Cheon Lee , Mi Ra Park , Yu-Kyung Park , Sung Jin Kim , Pil-Sung Kang , Heeyong Park , Ha Ju Park
发明人： Joung Han Yim , Il Chan Kim , Doc Kyu Kim , Se Jong Han , Hyoung Seok Lee , Bhattarai Hari Datta , Jung Eun Kim , Tai Kyoung Kim , Hyun Cheol Oh , Dong-Gyu Jo , Cheolsoon Lee , Keun-Sik Kim , Pyung Cheon Lee , Mi Ra Park , Yu-Kyung Park , Sung Jin Kim , Pil-Sung Kang , Heeyong Park , Ha Ju Park
IPC分类号： A61K31/357 , C07D321/10 , A61K36/09 , A23L1/30 , C07D307/88 , C07D307/89 , C07D313/12
CPC分类号： C07D321/10 , A23L33/105 , A23V2002/00 , A61K36/09 , C07D307/88 , C07D307/89 , C07D313/12 , A23V2200/3262 , A23V2200/332 , A23V2250/202
摘要： The present invention relates to pharmaceutical and food compositions for preventing or treating diabetes or obesity, and more particularly to pharmaceutical compositions and functional foods for preventing or treating diabetes or obesity, which contain, as an active ingredient, a novel compound synthesized from a compound separated from an extract of the Stereocaulon alpinum. The novel compounds of the invention have very excellent PTP-1b (protein tyrosine phosphatase-1b) inhibitory activities, act selectively only on PTP-1b among protein tyrosine phosphatases, and are substantial PTP-1b inhibitors which are effective in preventing or treating diabetes or obesity.

2. 发明申请

US20130261174A1 PHARMACEUTICAL AND FOOD COMPOSITIONS FOR PREVENTING OR TREATING DIABETES OR OBESITY 有权
标题翻译：用于预防或治疗糖尿病或肥胖的药物和食品组合物
公开(公告)号：US20130261174A1
公开(公告)日：2013-10-03
申请号：US13878196
申请日：2011-07-01
申请人： Joung Han Yim , Il Chan Kim , Doc Kyu Kim , Se Jong Han , Hyoung Seok Lee , Bhattarai Hari Datta , Jung Eun Kim , Tai Kyoung Kim , Hyun Cheol Oh , Dong-Gyu Jo , Cheolsoon Lee , Keun-Sik Kim , Pyung Cheon Lee , Mi Ra Park , Yu-Kyung Park , Sung Jin Kim , Pil-Sung Kang , Heeyong Park , Ha Ju Park
发明人： Joung Han Yim , Il Chan Kim , Doc Kyu Kim , Se Jong Han , Hyoung Seok Lee , Bhattarai Hari Datta , Jung Eun Kim , Tai Kyoung Kim , Hyun Cheol Oh , Dong-Gyu Jo , Cheolsoon Lee , Keun-Sik Kim , Pyung Cheon Lee , Mi Ra Park , Yu-Kyung Park , Sung Jin Kim , Pil-Sung Kang , Heeyong Park , Ha Ju Park
IPC分类号： C07D321/10
CPC分类号： C07D321/10 , A23L33/105 , A23V2002/00 , A61K36/09 , C07D307/88 , C07D307/89 , C07D313/12 , A23V2200/3262 , A23V2200/332 , A23V2250/202
摘要： The present invention relates to pharmaceutical and food compositions for preventing or treating diabetes or obesity, and more particularly to pharmaceutical compositions and functional foods for preventing or treating diabetes or obesity, which contain, as an active ingredient, a novel compound synthesized from a compound separated from an extract of the Stereocaulon alpinum. The novel compounds of the invention have very excellent PTP-1b (protein tyrosine phosphatase-1b) inhibitory activities, act selectively only on PTP-1b among protein tyrosine phosphatases, and are substantial PTP-1b inhibitors which are effective in preventing or treating diabetes or obesity.
摘要翻译：本发明涉及用于预防或治疗糖尿病或肥胖症的药物和食品组合物，更具体地涉及用于预防或治疗糖尿病或肥胖症的药物组合物和功能性食品，其含有由分离的化合物合成的新化合物作为活性成分从Stereocaulon alpinum的提取物。本发明的新型化合物具有非常优异的PTP-1b（蛋白酪氨酸磷酸酶-1b）抑制活性，仅在蛋白酪氨酸磷酸酶中仅对PTP-1b起作用，并且是可有效预防或治疗糖尿病的实质性PTP-1b抑制剂肥胖。

3. 发明授权

US08809578B2 Compound ramalin and use thereof 有权
标题翻译：化合物ramalin及其用途
公开(公告)号：US08809578B2
公开(公告)日：2014-08-19
申请号：US13128586
申请日：2009-11-10
申请人： Joung Han Yim , Hong Kum Lee , Hari Datta Bhattarai , Paudel Babita , Il Chan Kim , Soon Gyu Hong , Doc Kyu Kim , Yoo Kyung Lee , Sung Gu Lee , Hyun Cheol Oh
发明人： Joung Han Yim , Hong Kum Lee , Hari Datta Bhattarai , Paudel Babita , Il Chan Kim , Soon Gyu Hong , Doc Kyu Kim , Yoo Kyung Lee , Sung Gu Lee , Hyun Cheol Oh
IPC分类号： A61Q19/02 , A61Q19/08 , A23L1/29 , A61K8/42 , C07C243/34
CPC分类号： C07C243/34 , A23L33/00 , A23V2002/00 , A61K8/42 , A61K2800/522 , A61Q19/02 , A61Q19/08 , A23V2200/02 , A23V2200/302
摘要： The present invention relates to a novel compound having excellent antioxidant activity, isolated from Ramalina terebrata, and more particularly to a novel compound, RAMALIN™, having excellent antioxidant activity, isolated from the Antarctic lichen Ramalina terebrata, a method for preparing the RAMALIN™, and a pharmaceutical composition, a functional food and a functional cosmetic composition, which contain the RAMALIN™ as an active ingredient. The RAMALIN™ according to the invention has significantly excellent antioxidant effects compared to commercially available antioxidants, and thus can be widely used in agents for treating oxidation-related diseases, anti-aging functional foods, functional cosmetic products for skin whitening and wrinkle reduction, etc.
摘要翻译：本发明涉及一种从Ramalina terebrata分离得到的具有优异抗氧化活性的新型化合物，更具体地说涉及一种从南极地衣Ramalina terebrata分离得到的抗氧化活性优异的新型化合物RAMALIN TM，制备RAMALIN TM的方法，以及含有RAMALIN TM作为活性成分的药物组合物，功能性食品和功能性化妆品组合物。根据本发明的RAMALIN TM与市售抗氧化剂相比具有显着优异的抗氧化作用，因此可广泛用于治疗氧化相关疾病，抗衰老功能性食品，用于皮肤美白和皱纹减少的功能性化妆品等。。

4. 发明申请

US20110262374A1 NOVEL COMPOUND RAMALIN AND USE THEREOF 有权
标题翻译：新型化合物及其用途
公开(公告)号：US20110262374A1
公开(公告)日：2011-10-27
申请号：US13128586
申请日：2009-11-10
申请人： Joung Han Yim , Hong Kum Lee , Hari Datta Bhattarai , Paudel Babita , Il Chan Kim , Soon Gyu Hong , Doc Kyu Kim , Yoo Kyung Lee , Sung Gu Lee , Hyun Cheol Oh
发明人： Joung Han Yim , Hong Kum Lee , Hari Datta Bhattarai , Paudel Babita , Il Chan Kim , Soon Gyu Hong , Doc Kyu Kim , Yoo Kyung Lee , Sung Gu Lee , Hyun Cheol Oh
IPC分类号： A61K31/197 , A61P35/00 , A61P17/18 , A61P9/10 , A61K8/44 , A61P25/08 , A61P25/28 , A61Q19/02 , A61Q19/00 , C07C229/42 , A61P3/10
CPC分类号： C07C243/34 , A23L33/00 , A23V2002/00 , A61K8/42 , A61K2800/522 , A61Q19/02 , A61Q19/08 , A23V2200/02 , A23V2200/302
摘要： The present invention relates to a novel compound having excellent antioxidant activity, isolated from Ramalina terebrata, and more particularly to a novel compound, Ramalin, having excellent antioxidant activity, isolated from the Antarctic lichen Ramalina terebrata, a method for preparing the Ramalin, and a pharmaceutical composition, a functional food and a functional cosmetic composition, which contain the Ramalin as an active ingredient. The Ramalin according to the invention has significantly excellent antioxidant effects compared to commercially available antioxidants, and thus can be widely used in agents for treating oxidation-related diseases, anti-aging functional foods, functional cosmetic products for skin whitening and wrinkle reduction, etc.
摘要翻译：本发明涉及一种从Ramalina terebrata分离得到的具有优异抗氧化活性的新型化合物，更具体地说涉及一种从南极地衣Ramalina terebrata中分离得到的具有优异抗氧化活性的新化合物Ramalin，制备Ramalin的方法和药物组合物，功能性食品和功能性化妆品组合物，其含有拉马林作为活性成分。根据本发明的拉马林与市售的抗氧化剂相比具有显着优异的抗氧化作用，因此可广泛用于治疗氧化相关疾病，抗衰老功能性食品，用于皮肤美白和皱纹减少的功能性化妆品等。

5. 发明授权

US08454113B2 Ink discharge device of inkjet head and control method thereof 有权
标题翻译：喷墨头喷墨装置及其控制方法
公开(公告)号：US08454113B2
公开(公告)日：2013-06-04
申请号：US12923921
申请日：2010-10-14
申请人： Dong Woo Paeng , Kang Woong Ko , Jong Han Oh , Hyun Cheol Oh
发明人： Dong Woo Paeng , Kang Woong Ko , Jong Han Oh , Hyun Cheol Oh
IPC分类号： B41J2/205 , B41J29/38
CPC分类号： B41J2/2128 , B41J2202/12
摘要： Example embodiments are directed to an ink discharge device that discharges uniform amounts of ink droplets from an inkjet head, and a control method thereof. Voltages applied to plural nozzles of the ink-head are changed based on different characteristics of the respective nozzles to discharge uniform amounts of ink droplets from the nozzles. Voltage increments are calculated using a fixed target color value so as to set color value dispersion and voltage increments are calculated using different target color values according to the nozzles so as to satisfy color value differences between the neighboring pixels and thus time required for a DPN process is shortened, and excessive changes of the applied voltages are prevented and thus a preparatory period required to mass-produce an LCD panel is shortened and yield of the LCD panel is increased.
摘要翻译：示例性实施例涉及从喷墨头排出均匀量的墨滴的排墨装置及其控制方法。基于各喷嘴的不同特性来改变施加到墨头的多个喷嘴的电压，以从喷嘴排出均匀的墨滴量。使用固定的目标色彩值计算电压增量，以便设定颜色色散，并根据喷嘴使用不同的目标色彩值来计算电压增量，以便满足相邻像素之间的颜色值差异，从而满足DPN处理所需的时间并且防止施加电压的过度变化，因此大量生产LCD面板所需的准备时间缩短，并且LCD面板的产量增加。

6. 发明申请

US20110122187A1 Ink discharge device of inkjet head and control method thereof 有权
标题翻译：喷墨头喷墨装置及其控制方法
公开(公告)号：US20110122187A1
公开(公告)日：2011-05-26
申请号：US12923921
申请日：2010-10-14
申请人： Dong Woo Paeng , Kang Woong Ko , Jong Han Oh , Hyun Cheol Oh
发明人： Dong Woo Paeng , Kang Woong Ko , Jong Han Oh , Hyun Cheol Oh
IPC分类号： B41J2/205
CPC分类号： B41J2/2128 , B41J2202/12
摘要： Example embodiments are directed to an ink discharge device that discharges uniform amounts of ink droplets from an inkjet head, and a control method thereof. Voltages applied to plural nozzles of the ink-head are changed based on different characteristics of the respective nozzles to discharge uniform amounts of ink droplets from the nozzles. Voltage increments are calculated using a fixed target color value so as to set color value dispersion and voltage increments are calculated using different target color values according to the nozzles so as to satisfy color value differences between the neighboring pixels and thus time required for a DPN process is shortened, and excessive changes of the applied voltages are prevented and thus a preparatory period required to mass-produce an LCD panel is shortened and yield of the LCD panel is increased.
摘要翻译：示例性实施例涉及从喷墨头排出均匀量的墨滴的排墨装置及其控制方法。基于各喷嘴的不同特性来改变施加到墨头的多个喷嘴的电压，以从喷嘴排出均匀的墨滴量。使用固定的目标色彩值计算电压增量，以便设定颜色色散，并根据喷嘴使用不同的目标色彩值来计算电压增量，以便满足相邻像素之间的颜色值差异，从而满足DPN处理所需的时间并且防止施加电压的过度变化，因此大量生产LCD面板所需的准备时间缩短，并且LCD面板的产量增加。

7. 发明授权

US08506045B2 Inkjet head cleaning apparatus and method 有权
标题翻译：喷墨头清洗装置及方法
公开(公告)号：US08506045B2
公开(公告)日：2013-08-13
申请号：US13277267
申请日：2011-10-20
申请人： Kang Woong Ko , Hyun Cheol Oh , Dong Eog Kim , Dae Jung Kim
发明人： Kang Woong Ko , Hyun Cheol Oh , Dong Eog Kim , Dae Jung Kim
IPC分类号： B41J2/165
CPC分类号： B41J2/16585 , B41J2/16526 , B41J2/16538 , B41J2/16552
摘要： According to an example embodiment, an inkjet head cleaning apparatus that removes ink residue from an inkjet head after a purging operation in a non-contact manner includes a cleaning blade and a drive unit. The cleaning blade is at a distance from a bottom of the inkjet head. The drive unit is configured to move the cleaning blade in a direction parallel to the inkjet head bottom. The cleaning blade includes a flat upper surface parallel to the inkjet head bottom, and an ink film is produced between the flat upper surface of the cleaning blade and the inkjet head bottom. The cleaning blade also includes an elongated groove longitudinally in the upper surface of the cleaning blade.
摘要翻译：根据示例性实施例，一种在非接触式清洗操作之后从喷墨头去除墨残留物的喷墨头清洁装置包括清洁刮板和驱动单元。清洁刮板与喷墨头的底部距离一定距离。驱动单元构造成沿着与喷墨头底部平行的方向移动清洁刮板。清洁刮板包括与喷墨头底部平行的平坦的上表面，并且在清洁刮板的平坦的上表面和喷墨头底部之间产生墨膜。清洁刮板还包括在清洁刮板的上表面中纵向延伸的细长槽。

8. 发明申请

US20120120151A1 Inkjet Head Cleaning Apparatus And Method 有权
标题翻译：喷墨头清洁装置及方法
公开(公告)号：US20120120151A1
公开(公告)日：2012-05-17
申请号：US13277267
申请日：2011-10-20
申请人： Kang Woong Ko , Hyun Cheol Oh , Dong Eog Kim , Dae Jung Kim
发明人： Kang Woong Ko , Hyun Cheol Oh , Dong Eog Kim , Dae Jung Kim
IPC分类号： B41J2/165
CPC分类号： B41J2/16585 , B41J2/16526 , B41J2/16538 , B41J2/16552
摘要： According to an example embodiment, an inkjet head cleaning apparatus that removes ink residue from an inkjet head after a purging operation in a non-contact manner includes a cleaning blade and a drive unit. The cleaning blade is at a distance from a bottom of the inkjet head. The drive unit is configured to move the cleaning blade in a direction parallel to the inkjet head bottom. The cleaning blade includes a flat upper surface parallel to the inkjet head bottom, and an ink film is produced between the flat upper surface of the cleaning blade and the inkjet head bottom. The cleaning blade also includes an elongated groove longitudinally in the upper surface of the cleaning blade.
摘要翻译：根据一个示例性实施例，一种在非接触式清洗操作之后从喷墨头去除油墨残留的喷墨头清洁装置包括清洁刮板和驱动单元。清洁刮板与喷墨头的底部距离一定距离。驱动单元构造成沿着与喷墨头底部平行的方向移动清洁刮板。清洁刮板包括与喷墨头底部平行的平坦的上表面，并且在清洁刮板的平坦的上表面和喷墨头底部之间产生墨膜。清洁刮板还包括在清洁刮板的上表面中纵向延伸的细长槽。

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