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    • 2. 发明申请
    • SYSTEMS AND METHODS FOR THE TREATMENT OF PAIN THROUGH NEURAL FIBER STIMULATION
    • 通过神经纤维刺激治疗疼痛的系统和方法
    • US20120310314A1
    • 2012-12-06
    • US13309024
    • 2011-12-01
    • Maria E. BENNETTJoseph W. BOGGS, IIWarren M. GRILLJohn CHAE
    • Maria E. BENNETTJoseph W. BOGGS, IIWarren M. GRILLJohn CHAE
    • A61N1/04
    • A61N1/36071A61N1/36003A61N1/36017A61N1/36021A61N1/36057
    • Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate afferent pathways in a manner approximating natural afferent activity. The afferent fibers may be associated with primary receptors of muscle spindles, golgi tendon organs, secondary receptors of muscle spindles, joint receptors, touch receptors, and other types of mechanoreceptors and/or proprioceptors. If efferent fibers are stimulated, alone or in combination with afferent fibers, a therapeutically effective amount of electrical stimulation is applied to activate intrafusal and/or extrafusal muscle fibers, which results in an indirect activation of afferent fibers associated therewith.
    • 本发明的实施方案提供了通过激活选择性神经纤维来治疗疼痛的系统和方法。 神经纤维可以包含一个或多个传入神经纤维和/或一个或多个传出神经纤维。 如果传入纤维被单独或与传出纤维组合刺激,则施用治疗有效量的电刺激以以接近自然传入活性的方式激活传入途径。 传入纤维可能与肌肉锭,高尔基体腱器官,肌肉锭子的次要受体,关节受体,触觉受体和其他类型的机械感受器和/或本体感受器的主要受体相关联。 如果传出纤维被单独或与传入纤维组合刺激,则施加治疗有效量的电刺激以激活内部和/或外部肌肉纤维,这导致与其相关联的传入纤维的间接活化。