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1. 发明授权

US06752148B1 Medicament dry powder inhaler dispensing device 失效
标题翻译：药物干粉吸入器分配装置
公开(公告)号：US06752148B1
公开(公告)日：2004-06-22
申请号：US09623937
申请日：2000-09-01
申请人： Joseph T. McGinn , Suggy S. Chrai , Bogdan Brycki , Bawa Singh , Peter Coyle , Gary Santonastaso , Hoi Cheong Sun
发明人： Joseph T. McGinn , Suggy S. Chrai , Bogdan Brycki , Bawa Singh , Peter Coyle , Gary Santonastaso , Hoi Cheong Sun
IPC分类号： A61M1500
CPC分类号： A61M15/0045 , A61M15/0043 , A61M15/0048 , A61M15/0051 , A61M15/0055
摘要： An inhaler disc cartridge comprises a carrier disc with radially outwardly extending resilient fingers, each with a medicament powder dosage. A sealing disc and an indexing ring are bonded to the disc. A cam sequentially and manually deflects a selected finger causing it to snap against an anvil to release the dosage by momentum energy transfer. In other embodiments, a cassette includes a carrier substrate reel of deposited powder dosages with a dosage sealing tape. The substrate comprises a belt with a plurality of transversely extending triangular fingers, each finger tip with a dosage thereon. Each finger is snapped in sequence against an anvil while a clamp secures the belt as the fingers are deflected. The spring fingers are corrugated in one embodiment cooperating with an anvil having channels and a device for inducing agglomeration breakup air streams through the channels. Other embodiments are for impact deflection of a dosage carrying substrate in a cartridge or cassette against an anvil to release the dosages.
摘要翻译：一个吸入式盘盒包括一个具有径向向外延伸的弹性指状物的承载盘，每个都带有药物粉末剂量。密封盘和分度环结合到盘上。凸轮顺序地并且手动地偏转所选择的手指，使其与砧座卡扣以通过动量能量传递释放剂量。在其他实施例中，盒包括具有剂量密封带的沉积的粉末剂量的载体衬底卷轴。衬底包括具有多个横向延伸的三角形指状物的带，每个指尖具有其上的剂量。每个手指按照砧座顺序扣合，同时当手指偏转时，夹具固定皮带。在一个实施例中，弹簧指状物是波纹状的，与具有通道的砧座配合，以及用于通过通道引起团聚分解空气流的装置。其他实施方案是用于将剂量携带衬底在药筒或药盒中抵抗砧座的冲击挠曲以释放剂量。

2. 发明授权

US06527138B2 Medication dispenser for dispensing flat dosage forms 失效
标题翻译：用于分配平坦剂型的药物分配器
公开(公告)号：US06527138B2
公开(公告)日：2003-03-04
申请号：US10122808
申请日：2002-04-15
申请人： George R. Pawlo , Gary Santonastaso , Ramaswamy Murari , Suggy Chrai
发明人： George R. Pawlo , Gary Santonastaso , Ramaswamy Murari , Suggy Chrai
IPC分类号： B65H358
CPC分类号： A61J7/0409 , A61J1/035 , B65D83/0409 , B65D83/0463 , B65D83/0472
摘要： A dispenser for storing/dispensing pharmaceutical dosages that are provided in a stamplike (flat) dosage form. In some embodiments, the present dispenser includes a housing for retaining a plurality of stacked, individual “stamp-like” pharmaceutical dosages. Disposed within the housing beneath the dosages is a bias element, such as a helical spring, that urges the dosages towards a dosage delivery port of the housing. From the dosage delivery port, dosages are dispensed through an aperture. In other embodiments, the instant dispenser includes a cylindrical main body for retaining pharmaceutical dosages having a stamp-like dosage form that are collectively organized in a roll. A dosage delivery port depending from the cylindrical main body receives dosages one at a time therefrom. The present dispenser is configured, in various embodiments, for manual, mechanically assisted, or automated dispensing. Moreover, the present dispenser includes, when appropriately automated, control electronics that (1) alert a user of a scheduled dosage, and/or (2) dispense a dosage at a prescribed time or at a prescribed time interval, and/or (3) maintain a dosage record.
摘要翻译：用于存储/分配以stamplike（扁平）剂型提供的药物剂量的分配器。在一些实施例中，本发明的分配器包括用于保持多个堆叠的，单独的“邮票状”药物剂量的壳体。在剂量下的壳体内设置有偏压元件，例如螺旋弹簧，其将剂量推向壳体的剂量输送端口。从剂量递送口中，通过孔分配剂量。在其它实施方案中，瞬时分配器包括圆柱形主体，用于保持药物剂量，其具有共同组织成卷的戳状剂型。从圆柱形主体悬挂的剂量输送口从其一次接收剂量。在各种实施例中，本发明的分配器被配置用于手动，机械辅助或自动分配。此外，当适当地自动化时，本发明的分配器包括控制电子设备，（1）向用户警告计划的剂量，和/或（2）在规定的时间或以规定的时间间隔分配剂量，和/或（3 ）维持剂量记录。

3. 发明授权

US06394306B1 Medication dispenser for dispensing flat dosage forms 失效
标题翻译：用于分配平坦剂型的药物分配器
公开(公告)号：US06394306B1
公开(公告)日：2002-05-28
申请号：US09602314
申请日：2000-06-23
申请人： George R. Pawlo , Gary Santonastaso , Ramaswamy Murari , Suggy Chrai
发明人： George R. Pawlo , Gary Santonastaso , Ramaswamy Murari , Suggy Chrai
IPC分类号： G07F1100
CPC分类号： A61J7/0409 , A61J1/035 , B65D83/0409 , B65D83/0463 , B65D83/0472
摘要： A dispenser for storing/dispensing pharmaceutical dosages that are provided in a stamp-like (flat) dosage form. In some embodiments, the present dispenser includes a housing for retaining a plurality of stacked, individual “stamp-like” pharmaceutical dosages. Disposed within the housing beneath the dosages is a bias element, such as a helical spring, that urges the dosages towards a dosage delivery port of the housing. From the dosage delivery port, dosages are dispensed through an aperture. In other embodiments, the instant dispenser includes a cylindrical main body for retaining pharmaceutical dosages having a stamp-like dosage form that are collectively organized in a roll. A dosage delivery port depending from the cylindrical main body receives dosages one at a time therefrom. The present dispenser is configured, in various embodiments, for manual, mechanically assisted, or automated dispensing. Moreover, the present dispenser includes, when appropriately automated, control electronics that (1) alert a user of a scheduled dosage, and/or (2) dispense a dosage at a prescribed time or at a prescribed time interval, and/or (3) maintain a dosage record.
摘要翻译：用于存储/分配以邮票状（平坦）剂型提供的药物剂量的分配器。在一些实施例中，本发明的分配器包括用于保持多个堆叠的，单独的“邮票状”药物剂量的壳体。在剂量下的壳体内设置有偏压元件，例如螺旋弹簧，其将剂量推向壳体的剂量输送端口。从剂量递送口中，通过孔分配剂量。在其它实施方案中，瞬时分配器包括圆柱形主体，用于保持药物剂量，其具有共同组织成卷的戳状剂型。从圆柱形主体悬挂的剂量输送口从其一次接收剂量。在各种实施例中，本发明的分配器被配置用于手动，机械辅助或自动分配。此外，当适当地自动化时，本发明的分配器包括控制电子设备，（1）向用户警告计划的剂量，和/或（2）在规定的时间或以规定的时间间隔分配剂量，和/或（3 ）维持剂量记录。

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