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    • 2. 发明申请
    • Substituted heterocyclic compounds and methods of use
    • 取代的杂环化合物及其使用方法
    • US20050209221A1
    • 2005-09-22
    • US10875896
    • 2004-06-23
    • Joseph NunesXiaotian ZhuPatricia AmouzeghChiara GhironDavid JohnstonEoin Power
    • Joseph NunesXiaotian ZhuPatricia AmouzeghChiara GhironDavid JohnstonEoin Power
    • C07D213/82C07D239/46C07D239/48C07D417/02A61K31/4439A61K31/496A61K31/513A61K31/5377A61K31/541C07D413/02C07D43/02
    • C07D213/82C07D239/47C07D239/48
    • The present invention relates to pyrimidine or pyridine carboxamides or pharmaceutically-acceptable salts thereof. Also included is a method of treatment of inflammation, inhibition of T cell activation and proliferation, arthritis, rheumatoid arthritis, psoriatic arthritis, osteoarthritis, organ transplant, acute transplant or heterograft or homograft rejection, transplantation tolerance induction, ischemic or reperfusion injury, myocardial infarction, stroke, multiple sclerosis, inflammatory bowel disease, including ulcerative colitis, Crohn's disease, lupus, contact hypersensitivity, delayed-type hypersensitivity, and gluten-sensitive enteropathy, type 1 diabetes, psoriasis, contact dermatitis, Hashimoto's thyroiditis, Sjogren's syndrome, autoimmune hyperthyroidism, Addison's disease, autoimmune polyglandular disease, autoimmune alopecia, pernicious anemia, vitiligo, autoimmune hypopituatarism, Guillain-Barre syndrome, glomerulonephritis, serum sickness, uticaria, allergic diseases, asthma, hayfever, allergic rhinitis, scleracielma, mycosis fungoides, dermatomyositis, alopecia areata, chronic actinic dermatitis, eczema, Behcet's disease, Pustulosis palmoplanteris, Pyoderma gangrenum, Sezary's syndrome, atopic dermatitis, systemic schlerosis, morphea, atopic dermatitis, colon carcinoma or thymoma in a mammal comprising administering a therapeutically-effective amount a compound as described above.
    • 本发明涉及嘧啶或吡啶甲酰胺或其药学上可接受的盐。 还包括治疗炎症,抑制T细胞活化和增殖,关节炎,类风湿性关节炎,银屑病关节炎,骨关节炎,器官移植,急性移植或异种移植或同种移植物排斥,移植耐受性诱导,缺血或再灌注损伤,心肌梗死的方法 ,中风,多发性硬化,炎症性肠病,包括溃疡性结肠炎,克罗恩病,狼疮,接触性超敏反应,迟发型超敏反应和麸质敏感性肠病,1型糖尿病,牛皮癣,接触性皮炎,桥本氏甲状腺炎,干燥综合征,自身免疫性甲状腺功能亢进 ,艾迪生病,自身免疫性多腺病,自身免疫性脱发,恶性贫血,白癜风,自身免疫性低位症,吉兰巴利综合征,肾小球性肾炎,血清病,荨麻疹,过敏性疾病,哮喘,高粱,过敏性鼻炎,巩膜瘤,蕈样真菌病,皮肌炎,斑秃 ,慢性交感 包括给予治疗有效量的如上所述的化合物,包括给予治疗有效量的上述化合物,其中,所述治疗有效量的治疗有效量的药物组合物包括给予治疗有效量的上述化合物。
    • 5. 发明申请
    • DEVICE, METHOD, AND SYSTEM FOR SECURE TRUST ANCHOR PROVISIONING AND PROTECTION USING TAMPER-RESISTANT HARDWARE
    • 使用防潮硬件安全信赖锚定器和保护的装置,方法和系统
    • US20140095867A1
    • 2014-04-03
    • US13631562
    • 2012-09-28
    • Ned M. SmithDavid JohnstonGeorge W. CoxAdi Shaliv
    • Ned M. SmithDavid JohnstonGeorge W. CoxAdi Shaliv
    • H04L29/06H04L9/32G06F17/30H04L9/00H04L9/08
    • H04L63/061H04L9/0822H04L9/0866H04L9/3231H04L63/0861H04L2209/127
    • A method and device for securely provisioning trust anchors includes generating a database wrapper key as a function of computing device hardware. The database wrapper key encrypts a key database when it is not in use by a trusted execution environment and may be generated using a Physical Unclonable Function (PUF). A local computing device establishes a secure connection and security protocols with a remote computing device. In establishing the secure connection, the local computing device and remote computing device may exchange and/or authenticate cryptographic keys, including Enhanced Privacy Identification (EPID) keys, and establish a session key and device identifier(s). One or more trust anchors are then provisioned depending on whether unilateral, bilateral, or multilateral trust is established. The local computing device may act as a group or domain controller in establishing multilateral trust. Any of the devices may also require user presence to be verified.
    • 用于安全地配置信任锚的方法和设备包括生成作为计算设备硬件的函数的数据库包装密钥。 数据库包装器密钥在密钥数据库不被可信执行环境使用时加密,并且可以使用物理不可克隆功能(PUF)生成密钥数据库。 本地计算设备与远程计算设备建立安全连接和安全协议。 在建立安全连接时,本地计算设备和远程计算设备可以交换和/或验证密码密钥,包括增强型隐私标识(EPID)密钥,并建立会话密钥和设备标识符。 根据单方面,双边或多边信托是否建立了一个或多个信托基金。 本地计算设备可以充当组或域控制器来建立多边信任。 任何设备也可能要求验证用户存在。
    • 8. 发明授权
    • Techniques for communicating information over management channels
    • 通过管理渠道传达信息的技术
    • US08375205B2
    • 2013-02-12
    • US11864123
    • 2007-09-28
    • David Johnston
    • David Johnston
    • H04L29/06
    • H04W12/02H04L63/0428H04L63/105H04L63/162H04W8/00H04W80/02H04W84/12
    • Techniques for communicating information over management channels are described. An apparatus may comprise a classifier module operative to classify management information for a wireless communications network as media access control security management information or media access control management information. The apparatus may further comprise a wireless transceiver to couple to the classifier module, the wireless transceiver operative to communicate the media access control security management information over an insecure management connection and the media access control management information over a secure management connection. Other embodiments are described and claimed.
    • 描述了通过管理通道传递信息的技术。 装置可以包括分类器模块,用于将无线通信网络的管理信息分类为媒体访问控制安全管理信息或媒体访问控制管理信息。 该装置还可以包括无线收发器以耦合到分类器模块,无线收发器可操作以通过不安全的管理连接传送媒体访问控制安全管理信息,并通过安全管理连接传送媒体访问控制管理信息。 描述和要求保护其他实施例。