会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 2. 发明申请
    • N-SUBSTITUTED OXINDOLINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS
    • N-取代的氧化硅衍生物作为钙通道阻断剂
    • US20100204247A1
    • 2010-08-12
    • US12678820
    • 2008-09-30
    • Joseph L. DuffyScott B. HoytClare LondonChristian P. Stevenson
    • Joseph L. DuffyScott B. HoytClare LondonChristian P. Stevenson
    • A61K31/506A61K31/4439A61P25/08A61K31/4196
    • A61K31/405
    • A series of N-substituted oxindole derivatives represented by Formula I, or pharmaceutically acceptable salts thereof. Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more other therapeutically active compounds, and a pharmaceutically acceptable carrier. Methods of treating conditions associated with, or caused by, calcium channel activity, including, for example, acute pain, chronic pain, visceral pain, inflammatory pain, neuropathic pain, urinary incontinence, itchiness, allergic dermatitis, epilepsy, diabetic neuropathy, irritable bowel syndrome, depression, anxiety, multiple sclerosis, sleep disorder, bipolar disorder and stroke, comprise administering an effective amount of the present compounds, either alone, or in combination with one or more other therapeutically active compounds.
    • 一系列由式I表示的N-取代的羟基吲哚衍生物或其药学上可接受的盐。 药物组合物包含单独的或与一种或多种其它治疗活性化合物组合的有效量的本发明化合物和药学上可接受的载体。 治疗与钙通道活性相关或由其引起的疾病的方法,包括例如急性疼痛,慢性疼痛,内脏痛,炎性疼痛,神经性疼痛,尿失禁,瘙痒,过敏性皮炎,癫痫,糖尿病性神经病,肠易激综合征 综合征,抑郁症,焦虑症,多发性硬化症,睡眠障碍,双相性精神障碍和中风,包括单独施用有效量的本发明化合物或与一种或多种其它治疗活性化合物组合施用。
    • 3. 发明授权
    • N-substituted oxindoline derivatives as calcium channel blockers
    • N-取代的羟基吲哚衍生物作为钙通道阻断剂
    • US08273749B2
    • 2012-09-25
    • US12678357
    • 2008-09-30
    • Joseph L. DuffyScott B. HoytClare London
    • Joseph L. DuffyScott B. HoytClare London
    • A61K31/4015C07D209/34C07D241/14C07D401/04
    • C07D403/14C07D401/04C07D401/14C07D403/04
    • A series of N-substituted oxindole derivatives represented by Formula I, or pharmaceutically acceptable salts thereof. Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more other therapeutically active compounds, and a pharmaceutically acceptable carrier. Methods of treating conditions associated with, or caused by, calcium channel activity, including, for example, acute pain, chronic pain, visceral pain, inflammatory pain, neuropathic pain, urinary incontinence, itchiness, allergic dermatitis, epilepsy, diabetic neuropathy, irritable bowel syndrome, depression, anxiety, multiple sclerosis, sleep disorder, bipolar disorder and stroke, comprise administering an effective amount of the present compounds, either alone, or in combination with one or more other therapeutically active compounds.
    • 一系列由式I表示的N-取代的羟基吲哚衍生物或其药学上可接受的盐。 药物组合物包含单独的或与一种或多种其它治疗活性化合物组合的有效量的本发明化合物和药学上可接受的载体。 治疗与钙通道活性相关或由其引起的疾病的方法,包括例如急性疼痛,慢性疼痛,内脏痛,炎性疼痛,神经性疼痛,尿失禁,瘙痒,过敏性皮炎,癫痫,糖尿病性神经病,肠易激综合征 综合征,抑郁症,焦虑症,多发性硬化症,睡眠障碍,双相性精神障碍和中风,包括单独施用有效量的本发明化合物或与一种或多种其它治疗活性化合物组合施用。
    • 5. 发明授权
    • Benzaepinones as sodium channel blockers
    • Benzaepinones作为钠通道阻滞剂
    • US07888345B2
    • 2011-02-15
    • US12308209
    • 2007-06-05
    • Scott B. HoytClare LondonDong OkWilliam H. Parsons
    • Scott B. HoytClare LondonDong OkWilliam H. Parsons
    • C07D223/16A61K31/55A61P29/02
    • C07D223/16C07D401/12C07D403/12C07D409/12C07D413/12
    • Benzazepinone compounds represented by Formula (I), or pharmaceutically acceptable salts thereof. Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more other therapeutically active compounds, and a pharmaceutically acceptable carrier. Methods of treating conditions associated with, or caused by, sodium channel activity, including, for example, acute pain, chronic pain, visceral pain, inflammatory pain, neuropathic pain, epilepsy, irritable bowel syndrome, urinary incontinence, pruritis, itchiness, allergic dermatitis, depression, anxiety, multiple sclerosis, and bipolar disorder, comprise administering an effective amount of the present compounds, either alone, or in combination with one or more other therapeutically active compounds. A method of administering local anesthesia comprises administering an effective amount of a compound of the instant invention, either alone, or in combination with one or more other therapeutically active compounds, and a pharmaceutically acceptable carrier.
    • 由式(I)表示的苯并氮杂酮化合物或其药学上可接受的盐。 药物组合物包含单独的或与一种或多种其它治疗活性化合物组合的有效量的本发明化合物和药学上可接受的载体。 治疗与钠通道活性相关或由其引起的症状的方法,包括例如急性疼痛,慢性疼痛,内脏痛,炎性疼痛,神经性疼痛,癫痫,肠易激综合征,尿失禁,瘙痒,瘙痒,过敏性皮炎 抑郁,焦虑,多发性硬化和双相性精神障碍,包括单独施用有效量的本发明化合物或与一种或多种其它治疗活性化合物组合施用。 施用局部麻醉的方法包括单独施用有效量的本发明化合物或与一种或多种其它治疗活性化合物和药学上可接受的载体组合施用。